Hydration status regulates sodium flux and inflammatory pathways through epithelial sodium channel (ENaC) in the skin

Journal of Investigative Dermatology

Volumn 135, Issue 3, 2015, Pages 796-806

  Xu, Wei ^a   Hong, Seok Jong ^a   Zeitchek, Michael ^b   Cooper, Garry ^a   Jia, Shengxian ^a   Xie, Ping ^a   Qureshi, Hannan A ^a   Zhong, Aimei ^a,c   Porterfield, Marshall D ^b   Galiano, Robert D ^a   Surmeier, D James ^a   Mustoe, Thomas A ^a  

^a NORTHWESTERN UNIVERSITY   (United States)

^b PURDUE UNIVERSITY   (United States)

^c HUAZHONG UNIVERSITY OF SCIENCE AND TECHNOLOGY   (China)

Author keywords

[No Author keywords available]

Indexed keywords

2 MORPHOLINO 8 PHENYLCHROMONE; AMILORIDE; CELECOXIB; CYCLOOXYGENASE 2; CYCLOOXYGENASE 2 INHIBITOR; EPITHELIAL SODIUM CHANNEL; MESSENGER RNA; PROSTAGLANDIN E2; PROTEIN KINASE B; PHOSPHATIDYLINOSITOL 3 KINASE; SODIUM; WATER;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CELL ACTIVATION; CELL FUNCTION; COLLAGEN SYNTHESIS; CONTROLLED STUDY; ENZYME ACTIVITY; EX VIVO STUDY; EXPERIMENTAL RABBIT; FIBROBLAST; GENE EXPRESSION; GENE SILENCING; HEALTH STATUS; HUMAN; HUMAN CELL; HUMAN EX VIVO SKIN CULTURE; HUMAN TISSUE; HYDRATION; HYPERTROPHIC SCAR; IN VITRO STUDY; IN VIVO STUDY; INFLAMMATION; ION SELECTIVE ELECTRODE; KERATINOCYTE; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN PHOSPHORYLATION; PROTEIN SECRETION; RNA INTERFERENCE; SCAR FORMATION; SIGNAL TRANSDUCTION; SKIN; SKIN CULTURE; SKIN FIBROSIS; SKIN FUNCTION; SKIN HYDRATION; SODIUM METABOLISM; SODIUM TRANSPORT; UPREGULATION; WHOLE CELL PATCH CLAMP; WOUND HEALING; ANIMAL; ANTAGONISTS AND INHIBITORS; CELL COMMUNICATION; CELL CULTURE; CICATRIX; COCULTURE; DRUG EFFECTS; FEMALE; HOMEOSTASIS; METABOLISM; PATHOLOGY; PHYSIOLOGY; RABBIT;

ANIMALS; CELL COMMUNICATION; CELLS, CULTURED; CICATRIX; COCULTURE TECHNIQUES; CYCLOOXYGENASE 2; CYCLOOXYGENASE 2 INHIBITORS; DINOPROSTONE; EPITHELIAL SODIUM CHANNELS; FEMALE; FIBROBLASTS; HOMEOSTASIS; HUMANS; INFLAMMATION; KERATINOCYTES; MODELS, ANIMAL; PHOSPHATIDYLINOSITOL 3-KINASES; PROTO-ONCOGENE PROTEINS C-AKT; RABBITS; SIGNAL TRANSDUCTION; SKIN; SODIUM; WATER;

EID: 84922636594     PISSN: 0022202X     EISSN: 15231747     Source Type: Journal    
DOI: 10.1038/jid.2014.477     Document Type: Article

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