Epithelial sodium channel in human epidermal keratinocytes: Expression of its subunits and relation to sodium transport and differentiation

Journal of Cell Science

Volumn 112, Issue 19, 1999, Pages 3343-3352

  Brouard, Michel ^a   Casado, Mariano ^b   Djelidi, Sabri ^a   Barrandon, Yann ^a   Farman, Nicolette ^a  

^a INSERM   (France)

^b ECOLE NORMALE SUPÉRIEURE   (France)

Author keywords

Amiloride; Benzamil; ENaC; Epidermis; Hair follicle; Sodium transport

Indexed keywords

MEMBRANE ENZYME; MESSENGER RNA; SODIUM CHANNEL; SODIUM ION;

ARTICLE; CELL CULTURE; CELL DIFFERENTIATION; CELL PROLIFERATION; CONTROLLED STUDY; ENZYME SUBUNIT; EPIDERMIS; GENE EXPRESSION; HUMAN; HUMAN CELL; HUMAN TISSUE; KERATINOCYTE; PATCH CLAMP; PRIORITY JOURNAL; PROTEIN EXPRESSION; SKIN; SODIUM TRANSPORT;

AMILORIDE; BIOLOGICAL TRANSPORT; CELL DIFFERENTIATION; CELL SIZE; CELLS, CULTURED; ELECTRIC CONDUCTIVITY; EPIDERMIS; EPITHELIAL SODIUM CHANNEL; GENE EXPRESSION; HAIR FOLLICLE; HUMANS; KERATINOCYTES; PATCH-CLAMP TECHNIQUES; SODIUM; SODIUM CHANNELS;

EID: 0032704935     PISSN: 00219533     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (56)

1. Barrandon, Y. and Green, H. (1985). Cell size as a determinant of the clone-forming ability of human keratinocytes. Proc. Natl. Acad. Sci. USA 82, 5390-5394.
2. Barrandon, Y. and Green, H. (1987). Three clonal types of keratinocyte with different capacities for multiplication. Proc. Natl. Acad. Sci. USA 84, 2302-2306.
3. Blot-Chabaud, M., Laplace, M., Cluzeaud, F., Capurro, C., Cassingéna, R., Vandewalle, A., Farman, N. and Bonvalet, J.-P. (1996). Characteristics of a rat cortical collecting duct cell line that maintains high transepithelial resistance. Kidney Int. 50, 367-376.
4. Canessa, C., Horisberger, J.-D. and Rossier, B. (1993). Epithelial sodium channel related to proteins involved in neurodegeneration. Nature 361, 467-470.
5. + channel is made of three homologous subunits. Nature 367, 463-467.
6. Chalfie, M. and Sulston, J. (1981). Developmental genetics of the mecanosensory neurons of Caenorhabditis elegans. Dev. Biol. 82, 358-370.
7. Chang, S., Grunder, S., Hanukoglu, A., Rösler, A., Mathew, P., Hanukoglu, I., Schild, L., Lu, Y., Shimkets, R., Nelson-Williams, C., Rossier, B. and Lifton, R. (1996). Mutations in subunits of the epithelial sodium channel cause salt wasting with hyperkalaemic acidosis, pseudohypoaldosteronism type 1. Nature genet. 12, 248-253.
8. Chapman, S. and Eady, R. (1985). Blistering in keratinocyte cultures: a regular phenomenon associated with differentiation. Eur. J. Cell Biol. 39, 352-359.
9. Corey, D. and Garcia-Anoveros, J. (1996). Mechanosensation and the DEG/ENaC ion channels. Science 273, 323-4.
10. Crabbe, J. (1964). Stimulation by aldosterone of active sodium transport across the isolated ventral skin of amphibians. Endocrinology 75, 809-811.
11. Djelidi, S., Fay, M., Cluzeaud, F., Escoubet, B., Eugene, E., Capurro, C., Bonvalet, J. P., Farman, N. and Blot-Chabaud, M. (1997). Transcriptional regulation of sodium transport by vasopressin in renal cells. J. Biol. Chem. 272, 32919-32924.
12. Driscoll, M. and Chalfie, M. (1991). The mec-4 gene is a member of a family of Caenorhabditis elegans genes that can mutate to induce neuronal degeneration. Nature 349, 588-593.
13. Duc, C., Farman, N., Canessa, C., Bonvalet, J.-P. and Rossier, B. (1994). Cell-specific expression of epithelial sodium channel α, β, and γ subunits in aldosterone-responsive epithelia from the rat: localization by in situ hybridization and immunocytochemistry. J. Cell Biol. 127, 1907-1921.
14. Eckert, R. L. (1989). Structure, function, and differenciation of the keratinocyte. Physiol. Rev. 69, 1316-1346.
15. Elias, P. M., Menon, G. K., Grayson, S. and Brown, B. E. (1988). Membrane structural alterations in murine stratum corneum: relationship to the localization of polar lipids and phospholipases. J. Invest. Dermatol. 91, 3-10.
16. Escoubet, B., Coureau, C., Bonvalet, J.-P. and Farman, N. (1997). Noncoordinate regulation of epithelial Na channel and Na pump subunit mRNAs in kydney and colon by aldosterone. Am. J. Physiol. 272, 1482-1491.
17. + channel along rat respiratory tract. Am. J. Physiol. 272, C131-141.
18. Firsov, D., Gautschi, I., Merillat, A., Rossier, B. and Schild, L. (1998). The heterotetrameric architecture of the epithelial sodium channel (ENaC). EMBO J. 17, 344-352.
19. Fuchs, E. (1995). Keratins and the skin. Ann. Rev. Cell. Dev. Biol. 11, 123-153.
20. Garcia-Anoveros, J. and Corey, D. (1997). The molecules of mechanosensation. Annu. Rev. Neurosci. 20, 567-594.
21. Garty, H. and Palmer, L. (1997). Epithelial sodium channels: function, structure, and regulation. Physiol. Rev. 77, 359-396.
22. Green, H. (1977). Terminal differenciation of cultured human epidermal cells. Cell 11, 405-416.
23. Green, H, Fuchs, E. and Watt, F. (1982). Differentiated structural components of the keratinocyte. Cold Spring Harb. Symp. Quant. Biol. 46, 293-301
24. Hamill, O., Marty, A., Neher, E., Sakmann, B. and Sigworth, F. (1981). Improved patch-clamp techniques for high-resolution current recording from cells and cell-free membrane patches. Pflügers Arch. 391, 83-100.
25. + channels. Membr. Biochem. 6, 149-171.
26. Hardman, M. J., Sisi, P., Banbury, D. N. and Byrne C. (1998). Patterned acquisition of skin barrier function during development. Development 125, 1541-1552.
27. Holbrook, K. A. and Wolff, K. (1987). The structure and development of skin. In Dermatology In General Medicine (ed. T. B. Fitzpatrick, A. Z. Lessen, K. Wolff, I. M. Freedberg and K. F. Austen), pp. 93-131. New-York: McGraw Hill.
28. Horisberger, J.-D. (1998). Amiloride-sensitive Na channels. Curr. Opin. Cell Biol. 10, 443-449.
29. Huang, M. and Chalfie, M. (1994). Gene interactions affecting mechanosensory transduction in Caenorhabditis elegans. Nature 367, 467-470.
30. Jefferson, D., Cobb, M., Gennaro, J. and Scott, W. (1980). Transporting renal epithelium: culture in hormonally defined serum-free medium. Science 210, 912-914.
31. Kitajima, Y., Eguchi, K., Ohno, T., Mori, S., Yaoita, H. (1983). Tight junctions of human keratinocytes in primary culture: a freeze-fracture study. J. Ultrastruct. Res. 82, 309-313.
32. Kuroki, D., Minden, A., Sanchez, I. and Wattenberg, E. (1997). Regulation of a c-jun amino-terminal kinase/stress-activated protein kinase cascade by a sodium-dependent signal transduction pathway. J. Biol. Chem. 272, 23905-23911.
33. Lever, J. (1979). Inducers of mammalian cell differentiation stimulate dome formation in a differentiated kidney epithelial cell line (MDCK). Proc. Natl. Acad. Sci. USA 76, 1323-1327.
34. + channel. FEBS Lett. 318, 95-99.
35. Lingueglia, E., Champigny, G., Lazdunski, M. and Barbry, P. (1995). Cloning of the amiloride-sensitive FMRFamide peptide-gated sodium channel. Nature 378, 730-733.
36. Liu, J., Schrank, B. and Waterston, R. (1996). Interaction between a putative mechanosensory membrane channel and a collagen. Science 273, 361-364.
37. ++-induced keratinocyte differentiation. J. Invest. Dermatol. 105, 203-208.
38. McDonald, F., Price, M., Snyder, P. and Welsh, M. (1995). Cloning and expression of the β- and γ-subunits of the human epithelial sodium channel. Am. J. Physiol. 268, C1157-C1163.
39. McNicholas, C. and Canessa, C. (1997). Diversity of channels generated by different combinations of epithelial sodium channel subunits. J. Gen. Physiol. 109, 681-692.
40. Quinton, P. (1987). Physiology of sweat secretion. Kidney Int. 32, S102-S108.
41. Rheinwald, J. and Green, H. (1975). Serial cultivation of strains of human epidermal keratinocytes: the formation of keratinizing colonies from single cells. Cell 6, 331-344.
42. Rice, R. H. and Green, H. (1979). Presence in human epidermal cells of a soluble protein precursor of the cross-linked envelope: activation of the cross-linking by calcium ions. Cell 18, 681-694.
43. Rochat, A., Kobayashi, K. and Barrandon, Y. (1994). Location of stem cells of human hair follicles by clonal analysis. Cell. 76, 1063-1073.
44. Roudier-Pujol, C., Rochat, A., Escoubet, B., Eugène, E., Barrandon, Y., Bonvalet, J.-P. and Farman, N. (1996). Differential expression of epithelial sodium channel subunit mRNAs in rat skin. J. Cell Sci. 109, 379-385.
45. Shimkets, R., Warnock, D., Bositis, C., Nelson-Williams, C., Hansson, J., Schambelan, M., Gill, J., Ulick, S., Milora, R., Findling, J., Canessa, C., Rossier, B. and Lifton, R. (1994). Liddle's syndrome: heritable human hypertension caused by mutations in the beta subunit of the epithelial sodium channel. Cell 79, 407-414.
46. Snyder, P., Cheng, C., Prince, L., Rogers, J. and Welsh, M. (1998). Electrophysiological and biochemical evidence that DEG/ENaC cation channels are composed of nine subunits. J. Biol. Chem. 273, 681-684.
47. Sugahara, K., Caldwell, J. and Mason, J. (1984). Electrical currents flow out of domes formed by cultured epithelial cells. J. Cell Biol. 99, 1541-1546.
48. Tavernarakis, N., Shreffler, W., Wang, S. and Driscoll, M. (1997). Unc-8, a DEG/ENaC family member, encodes a subunit of a candidate mechanically gated channel that modulates C. elegans locomotion. Neuron 18, 107-119.
49. Todaro, G. and Green, H. (1963). Quantitative studies of the growth of mouse embryo cells in culture and their development into established lines. J Cell Biol. 17, 299-312.
50. Tseng, H. and Green, H. (1994). Association of basonuclin with ability of keratinocytes to multiply and with absence of terminal differentiation. J. Cell Biol. 126, 495-506.
51. + channel: biophysical properties, pharmacology, ontogenesis, and molecular cloning. Proc. Natl. Acad. Sci. USA 91, 247-251.
52. Voilley, N., Bassilana, F., Mignon, C., Merscher, S., Mattéi, M.-G., Carle, G., Lazdunski, M. and Barbry, P. (1995). Cloning, chromosomal localization, and physical linkage of the β and γ subunits (SCNN1B and SCNN1G) of the human epithelial amiloride-sensitive sodium channel. Genomics 28, 560-565.
53. Waldmann, R., Champigny, G., Voilley, N., Lauritzen, I. and Lazdunski, M. (1996). The mammalian degenerin MDEG, an amiloride-sensitive cation channel activated by mutations causing neurodegeneration in Caenorhabditis elegans. J. Biol. Chem. 271, 10433-10436
54. Waldmann, R., Champigny, G., Bassilana, F., Heurteaux, C. and Lazdunski, M. (1997). A proton-gated cation channel involved in acid-sensing. Nature 386, 173-177.
55. Watt, F. M. and Green, H. (1981). Involucrin synthesis is correlated with cell size in human epidermal cultures. J. Cell Biol. 90, 738-742.
56. Watt, F. M. and Green, H. (1982). Stratification and terminal differentiation of cultured epidermal cells. Nature 295, 434-436.