메뉴 건너뛰기




Volumn 92, Issue 4, 2012, Pages 584-599

Application of a partial-thickness human ex vivo skin culture model in cutaneous wound healing study

Author keywords

collagen reproduction; human skin ex vivo culture; keratinocyte apoptosis; keratinocyte differentiation; keratinocyte migration; keratinocyte proliferation; wound healing

Indexed keywords

BULLOUS PEMPHIGOID ANTIGEN 1; COLLAGEN; CYTOKERATIN 6; PROTEIN;

EID: 84859332739     PISSN: 00236837     EISSN: 15300307     Source Type: Journal    
DOI: 10.1038/labinvest.2011.184     Document Type: Article
Times cited : (75)

References (47)
  • 1
    • 0034053029 scopus 로고    scopus 로고
    • Models for use in wound healing research: A survey focusing on in vitro and in vivo adult soft tissue
    • DOI 10.1046/j.1524-475X.2000.00083.x
    • Gottrup F, Agren MS, Karlsmark T. Models for use in wound healing research: a survey focusing on in vitro and in vivo adult soft tissue. Wound Repair Regen 2000;8:83-96. (Pubitemid 30238321)
    • (2000) Wound Repair and Regeneration , vol.8 , Issue.2 , pp. 83-96
    • Gottrup, F.1    Agren, M.S.2    Karlsmark, T.3
  • 2
    • 1242291507 scopus 로고    scopus 로고
    • Wound healing studies in transgenic and knockout mice. A review
    • Grose R, Werner S. Wound healing studies in transgenic and knockout mice. A review. Methods Mol Med 2003;78:191-216.
    • (2003) Methods Mol Med , vol.78 , pp. 191-216
    • Grose, R.1    Werner, S.2
  • 3
    • 9644263852 scopus 로고    scopus 로고
    • Rat models of skin wound healing: A review
    • DOI 10.1111/j.1067-1927.2004.12601.x
    • Dorsett-Martin WA. Rat models of skin wound healing: a review. Wound Repair Regen 2004;12:591-599. (Pubitemid 39579371)
    • (2004) Wound Repair and Regeneration , vol.12 , Issue.6 , pp. 591-599
    • Dorsett-Martin, W.A.1
  • 4
    • 0025327460 scopus 로고
    • Effects of ischemia on ulcer wound healing: A new model in the rabbit ear
    • Ahn ST, Mustoe TA. Effects of ischemia on ulcer wound healing: a new model in the rabbit ear. Ann Plast Surg 1990;24:17-23. (Pubitemid 20093496)
    • (1990) Annals of Plastic Surgery , vol.24 , Issue.1 , pp. 17-23
    • Ahn, S.T.1    Mustoe, T.A.2
  • 5
    • 77957176300 scopus 로고
    • A wound healing study of chlorhexidine digluconate in guinea pigs
    • DOI 10.1016/0272-0590(86)90258-7
    • Saatman RA, Carlton WW, Hubben K, et al. A wound healing study of chlorhexidine digluconate in guinea pigs. Fundam Appl Toxicol 1986;6:1-6. (Pubitemid 16177742)
    • (1986) Fundamental and Applied Toxicology , vol.6 , Issue.1 , pp. 1-6
    • Saatman, R.A.1    Carlton, W.W.2    Hubben, K.3
  • 6
    • 77953230696 scopus 로고    scopus 로고
    • A novel human skin chamber model to study wound infection ex vivo
    • Steinstraesser L, Sorkin M, Niederbichler AD, et al. A novel human skin chamber model to study wound infection ex vivo. Arch Dermatol Res 2010;302:357-365.
    • (2010) Arch Dermatol Res , vol.302 , pp. 357-365
    • Steinstraesser, L.1    Sorkin, M.2    Niederbichler, A.D.3
  • 7
    • 0032735236 scopus 로고    scopus 로고
    • Thalidomide increases human keratinocyte migration and proliferation
    • Nasca MR, O'Toole EA, Palicharla P, et al. Thalidomide increases human keratinocyte migration and proliferation. J Invest Dermatol 1999;113: 720-724.
    • (1999) J Invest Dermatol , vol.113 , pp. 720-724
    • Nasca, M.R.1    O'Toole, E.A.2    Palicharla, P.3
  • 8
    • 40249088473 scopus 로고    scopus 로고
    • In vitro human keratinocyte migration rates are associated with SNPs in the KRT1 interval
    • Tao H, Berno AJ, Cox DR, et al. In vitro human keratinocyte migration rates are associated with SNPs in the KRT1 interval. PLoS One 2007;2:e697.
    • (2007) PLoS One , vol.2
    • Tao, H.1    Berno, A.J.2    Cox, D.R.3
  • 9
    • 78650419019 scopus 로고    scopus 로고
    • MMP- and TIMP-secretion by human cutaneous keratinocytes and fibroblasts-impact of coculture and hydration
    • Tandara AA, Mustoe TA. MMP- and TIMP-secretion by human cutaneous keratinocytes and fibroblasts-impact of coculture and hydration. J Plast Reconstr Aesthet Surg 2011;64:108-116.
    • (2011) J Plast Reconstr Aesthet Surg , vol.64 , pp. 108-116
    • Tandara, A.A.1    Mustoe, T.A.2
  • 10
    • 34147174468 scopus 로고    scopus 로고
    • A new in vitro wound model based on the co-culture of human dermal microvascualr endothelial cells and human dermal fibroblasts
    • DOI 10.1042/BC20060116
    • Oberringer M, Meins C, Bubel M, et al. A new in vitro wound model based on the co-culture of human dermal microvascular endothelial cells and human dermal fibroblasts. Biol Cell 2007;99:197-207. (Pubitemid 46567177)
    • (2007) Biology of the Cell , vol.99 , Issue.4 , pp. 197-207
    • Oberringer, M.1    Meins, C.2    Bubel, M.3    Pohlemann, T.4
  • 11
    • 0028361407 scopus 로고
    • Fate of human keratinocytes during reepithelialization in an organotypic culture model
    • Garlick JA, Taichman LB. Fate of human keratinocytes during reepithelialization in an organotypic culture model. Lab Invest 1994;70:916-924. (Pubitemid 24209493)
    • (1994) Laboratory Investigation , vol.70 , Issue.6 , pp. 916-924
    • Garlick, J.A.1    Taichman, L.B.2
  • 12
    • 0034083737 scopus 로고    scopus 로고
    • Keratinocyte growth regulation in defined organotypic cultures through IL-1-induced keratinocyte growth factor expression in resting fibroblasts
    • DOI 10.1046/j.1523-1747.2000.00987.x
    • Maas-Szabowski N, Stark HJ, Fusenig NE. Keratinocyte growth regulation in defined organotypic cultures through IL-1-induced keratinocyte growth factor expression in resting fibroblasts. J Invest Dermatol 2000;114:1075-1084. (Pubitemid 30415221)
    • (2000) Journal of Investigative Dermatology , vol.114 , Issue.6 , pp. 1075-1084
    • Maas-Szabowski, N.1    Stark, H.-J.2    Fusenig, N.E.3
  • 13
    • 58549117679 scopus 로고    scopus 로고
    • Novel organotypic cultures of human skin explants with an implant-tissue biomaterial interface
    • Peramo A, Marcelo CL, Goldstein SA, et al. Novel organotypic cultures of human skin explants with an implant-tissue biomaterial interface. Ann Biomed Eng 2009;37:401-409.
    • (2009) Ann Biomed Eng , vol.37 , pp. 401-409
    • Peramo, A.1    Marcelo, C.L.2    Goldstein, S.A.3
  • 14
    • 0026733679 scopus 로고
    • Full-thickness skin wound explants in tissue culture: A mechanical evaluation of healing
    • Greenwald DP, Gottlieb LJ, Mass DP, et al. Full-thickness skin wound explants in tissue culture: a mechanical evaluation of healing. Plast Reconstr Surg 1992;90:289-294.
    • (1992) Plast Reconstr Surg , vol.90 , pp. 289-294
    • Greenwald, D.P.1    Gottlieb, L.J.2    Mass, D.P.3
  • 16
    • 0036668148 scopus 로고    scopus 로고
    • Tissue response and biomaterial integration: The efficacy of in vitro methods
    • Kirkpatrick CJ, Krump-Konvalinkova V, Unger RE, et al. Tissue response and biomaterial integration: the efficacy of in vitro methods. Biomol Eng 2002;19:211-217.
    • (2002) Biomol Eng , vol.19 , pp. 211-217
    • Kirkpatrick, C.J.1    Krump-Konvalinkova, V.2    Unger, R.E.3
  • 18
    • 0024447475 scopus 로고
    • Cultures of fibroblasts in fibrin lattices: Models for the study of metabolic activities of the cells in physiological conditions
    • Gillery P, Bellon G, Coustry F, et al. Cultures of fibroblasts in fibrin lattices: models for the study of metabolic activities of the cells in physiological conditions. J Cell Physiol 1989;140:483-490. (Pubitemid 19241764)
    • (1989) Journal of Cellular Physiology , vol.140 , Issue.3 , pp. 483-490
    • Gillery, P.1    Bellon, G.2    Coustry, F.3    Borel, J.-P.4
  • 19
    • 0031656035 scopus 로고    scopus 로고
    • Human psoriatic skin in organ culture: Comparison with normal skin exposed to exogenous growth factors and effects of an antibody to the EGF receptor
    • DOI 10.1159/000028031
    • Varani J, Kang S, Stoll S, et al. Human psoriatic skin in organ culture: comparison with normal skin exposed to exogenous growth factors and effects of an antibody to the EGF receptor. Pathobiology 1998;66:253-259. (Pubitemid 28470300)
    • (1998) Pathobiology , vol.66 , Issue.6 , pp. 253-259
    • Varani, J.1    Kang, S.2    Stoll, S.3    Elder, J.T.4
  • 20
    • 0028940048 scopus 로고
    • Detection of inflammatory cytokines in psoriatic skin
    • Yoshinaga Y, Higaki M, Terajima S, et al. Detection of inflammatory cytokines in psoriatic skin. Arch Dermatol Res 1995;287:158-164.
    • (1995) Arch Dermatol Res , vol.287 , pp. 158-164
    • Yoshinaga, Y.1    Higaki, M.2    Terajima, S.3
  • 21
    • 0028894842 scopus 로고
    • In situ behavior of human Langerhans cells in skin organ culture
    • Rambukkana A, Bos JD, Irik D, et al. In situ behavior of human Langerhans cells in skin organ culture. Lab Invest 1995;73:521-531.
    • (1995) Lab Invest , vol.73 , pp. 521-531
    • Rambukkana, A.1    Bos, J.D.2    Irik, D.3
  • 27
    • 22744439621 scopus 로고    scopus 로고
    • Reorganization of hair follicles in human skin organ culture induced by cultured human follicle-derived cells
    • DOI 10.1111/j.0906-6705.2005.00330.x
    • Krugluger W, Rohrbacher W, Laciak K, et al. Reorganization of hair follicles in human skin organ culture induced by cultured human follicle-derived cells. Exp Dermatol 2005;14:580-585. (Pubitemid 41030924)
    • (2005) Experimental Dermatology , vol.14 , Issue.8 , pp. 580-585
    • Krugluger, W.1    Rohrbacher, W.2    Laciak, K.3    Moser, K.4    Moser, C.5    Hugeneck, J.6
  • 28
    • 0033497525 scopus 로고    scopus 로고
    • Maintenance of human skin in organ culture: Role for insulin-like growth factor-1 receptor and epidermal growth factor receptor
    • Tavakkol A, Varani J, Elder JT, et al. Maintenance of human skin in organ culture: role for insulin-like growth factor-1 receptor and epidermal growth factor receptor. Arch Dermatol Res 1999;291: 643-651. (Pubitemid 30326286)
    • (1999) Archives of Dermatological Research , vol.291 , Issue.12 , pp. 643-651
    • Tavakkol, A.1    Varani, J.2    Elder, J.T.3    Zouboulis, C.C.4
  • 29
    • 0031879461 scopus 로고    scopus 로고
    • Characterization of epidermal wound healing in a human skin organ culture model: Acceleration by transplanted keratinocytes
    • DOI 10.1046/j.1523-1747.1998.00265.x
    • Moll I, Houdek P, Schmidt H, et al. Characterization of epidermal wound healing in a human skin organ culture model: acceleration by transplanted keratinocytes. J Invest Dermatol 1998;111:251-258. (Pubitemid 28354712)
    • (1998) Journal of Investigative Dermatology , vol.111 , Issue.2 , pp. 251-258
    • Moll, I.1    Houdek, P.2    Schmidt, H.3    Moll, R.4
  • 30
    • 0020601705 scopus 로고
    • Methods for cultivation of keratinocytes with an air-liquid interface
    • Prunieras M, Regnier M, Woodley D. Methods for cultivation of keratinocytes with an air-liquid interface. J Invest Dermatol 1983;81 (1 Suppl):28s-33s. (Pubitemid 13030410)
    • (1983) Journal of Investigative Dermatology , vol.81 , Issue.1 SUPPL.
    • Prunieras, M.1    Regnier, M.2    Woodley, D.3
  • 32
    • 33845425028 scopus 로고    scopus 로고
    • Towards the development of a simplified long-term organ culture method for human scalp skin and its appendages under serum-free conditions
    • DOI 10.1111/j.1600-0625.2006.00510.x
    • Lu Z, Hasse S, Bodo E, et al. Towards the development of a simplified long-term organ culture method for human scalp skin and its appendages under serum-free conditions. Exp Dermatol 2007;16: 37-44. (Pubitemid 44890349)
    • (2007) Experimental Dermatology , vol.16 , Issue.1 , pp. 37-44
    • Lu, Z.1    Hasse, S.2    Bodo, E.3    Rose, C.4    Funk, W.5    Paus, R.6
  • 33
    • 77953229791 scopus 로고    scopus 로고
    • A human full-skin culture system for interventional studies
    • Steinstraesser L, Rittig A, Gevers K, et al. A human full-skin culture system for interventional studies. Eplasty 2009;9:e5.
    • (2009) Eplasty , vol.9
    • Steinstraesser, L.1    Rittig, A.2    Gevers, K.3
  • 34
    • 0032532129 scopus 로고    scopus 로고
    • The two functional keratin 6 genes of mouse are differentially regulated and evolved independently from their human orthologs
    • DOI 10.1006/geno.1998.5476
    • Takahashi K, Yan B, Yamanishi K, et al. The two functional keratin 6 genes of mouse are differentially regulated and evolved independently from their human orthologs. Genomics 1998;53: 170-183. (Pubitemid 28496607)
    • (1998) Genomics , vol.53 , Issue.2 , pp. 170-183
    • Takahashi, K.1    Yan, B.2    Yamanishi, K.3    Imamura, S.4    Coulombe, P.A.5
  • 35
    • 0024558106 scopus 로고
    • Structure and biological activity of basement membrane proteins
    • DOI 10.1111/j.1432-1033.1989.tb14673.x
    • Timpl R. Structure and biological activity of basement membrane proteins. Eur J Biochem 1989;180:487-502. (Pubitemid 19111111)
    • (1989) European Journal of Biochemistry , vol.180 , Issue.3 , pp. 487-502
    • Timpl, R.1
  • 36
    • 3042733154 scopus 로고    scopus 로고
    • Inhibition of basement membrane formation by a nidogen-binding laminin gamma1-chain fragment in human skin-organotypic cocultures
    • DOI 10.1242/jcs.01127
    • Breitkreutz D, Mirancea N, Schmidt C, et al. Inhibition of basement membrane formation by a nidogen-binding laminin gamma1-chain fragment in human skin-organotypic cocultures. J Cell Sci 2004;117(Part 12):2611-2622. (Pubitemid 38877856)
    • (2004) Journal of Cell Science , vol.117 , Issue.12 , pp. 2611-2622
    • Breitkreutz, D.1    Mirancea, N.2    Schmidt, C.3    Beck, R.4    Werner, U.5    Stark, H.-J.6    Gerl, M.7    Fusenig, N.E.8
  • 37
    • 0027256508 scopus 로고
    • Multi-faceted regulation of cell differentiation by extracellular matrix
    • Lin CQ, Bissell MJ. Multi-faceted regulation of cell differentiation by extracellular matrix. FASEB J 1993;7:737-743. (Pubitemid 23199531)
    • (1993) FASEB Journal , vol.7 , Issue.9 , pp. 737-743
    • Lin, C.Q.1    Bissell, M.J.2
  • 38
    • 0031845096 scopus 로고    scopus 로고
    • Dynamics of basement membrane formation by keratinocyte-fibroblast interactions in organotypic skin culture
    • DOI 10.1006/excr.1997.3910
    • Smola H, Stark HJ, Thiekotter G, et al. Dynamics of basement membrane formation by keratinocyte-fibroblast interactions in organotypic skin culture. Exp Cell Res 1998;239:399-410. (Pubitemid 28366640)
    • (1998) Experimental Cell Research , vol.239 , Issue.2 , pp. 399-410
    • Smola, H.1    Stark, H.-J.2    Thiekotter, G.3    Mirancea, N.4    Krieg, T.5    Fusenig, N.E.6
  • 39
    • 0031864355 scopus 로고    scopus 로고
    • Organized skin structure is regenerated in vivo from collagen-GAG matrices seeded with autologous keratinocytes
    • DOI 10.1046/j.1523-1747.1998.00200.x
    • Compton CC, Butler CE, Yannas IV, et al. Organized skin structure is regenerated in vivo from collagen-GAG matrices seeded with autologous keratinocytes. J Invest Dermatol 1998;110:908-916. (Pubitemid 28237697)
    • (1998) Journal of Investigative Dermatology , vol.110 , Issue.6 , pp. 908-916
    • Compton, C.C.1    Butler, C.E.2    Yannas, I.V.3    Warland, G.4    Orgill, D.P.5
  • 40
    • 0034028524 scopus 로고    scopus 로고
    • Higher numbers of autologous fibroblasts in an artificial dermal substitute improve tissue regeneration and modulate scar tissue formation
    • DOI 10.1002/(SICI)1096-9896(200004)190:5<595::AID-PATH572>3.0.CO;2- V
    • Lamme EN, Van Leeuwen RT, Brandsma K, et al. Higher numbers of autologous fibroblasts in an artificial dermal substitute improve tissue regeneration and modulate scar tissue formation. J Pathol 2000;190: 595-603. (Pubitemid 30164490)
    • (2000) Journal of Pathology , vol.190 , Issue.5 , pp. 595-603
    • Lamme, E.N.1    Van Leeuwen, R.T.J.2    Brandsma, K.3    Van Marie, J.4    Middelkoop, E.5
  • 41
    • 0033845319 scopus 로고    scopus 로고
    • Evaluation of dermal-epidermal skin equivalents ('composite-skin') of human keratinocytes in a collagen-glycosaminoglycan matrix (Integra(TM) artificial skin)
    • DOI 10.1054/bjps.2000.3368
    • Kremer M, Lang E, Berger AC. Evaluation of dermal-epidermal skin equivalents ('composite-skin') of human keratinocytes in a collagen- glycosaminoglycan matrix (integra artificial skin). Br J Plast Surg 2000;53:459-465. (Pubitemid 30649036)
    • (2000) British Journal of Plastic Surgery , vol.53 , Issue.6 , pp. 459-465
    • Kremer, M.1    Lang, E.2    Berger, A.3
  • 42
    • 0034333782 scopus 로고    scopus 로고
    • The effect of a tissue engineered bilayered living skin analog, over meshed split-thickness autografts on the healing of excised burn wounds
    • DOI 10.1016/S0305-4179(00)00017-6, PII S0305417900000176
    • Waymack P, Duff RG, Sabolinski M. The effect of a tissue engineered bilayered living skin analog, over meshed split-thickness autografts on the healing of excised burn wounds. The Apligraf Burn Study Group. Burns 2000;26:609-619. (Pubitemid 30488056)
    • (2000) Burns , vol.26 , Issue.7 , pp. 609-619
    • Waymack, P.1    Duff, R.G.2    Sabolinski, M.3
  • 45
    • 0028249248 scopus 로고
    • Endothelial cell markers CD31, CD34, and BNH9 antibody to H- and Y-antigens-evaluation of their specificity and sensitivity in the diagnosis of vascular tumors and comparison with von Willebrand factor
    • Miettinen M, Lindenmayer AE, Chaubal A. Endothelial cell markers CD31, CD34, and BNH9 antibody to H- and Y-antigens-evaluation of their specificity and sensitivity in the diagnosis of vascular tumors and comparison with von Willebrand factor. Mod Pathol 1994;7:82-90.
    • (1994) Mod Pathol , vol.7 , pp. 82-90
    • Miettinen, M.1    Lindenmayer, A.E.2    Chaubal, A.3
  • 46
    • 0029900944 scopus 로고    scopus 로고
    • Immunohistochemical study of CD34-positive dendritic cells of human dermis
    • DOI 10.1097/00000372-199606000-00008
    • Narvaez D, Kanitakis J, Faure M, et al. Immunohistochemical study of CD34-positive dendritic cells of human dermis. Am J Dermatopathol 1996;18:283-288. (Pubitemid 26230854)
    • (1996) American Journal of Dermatopathology , vol.18 , Issue.3 , pp. 283-288
    • Narvaez, D.1    Kanitakis, J.2    Faure, M.3    Claudy, A.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.