Generation of neuropeptidergic hypothalamic neurons from human pluripotent stem cells

Development (Cambridge)

Volumn 142, Issue 4, 2015, Pages 633-643

  Merkle, Florian T ^a,b,c,d   Maroof, Asif ^a,c,d   Wataya, Takafumi ^e,f   Sasai, Yoshiki ^e   Studer, Lorenz ^g   Eggan, Kevin ^a,b,c,d   Schier, Alexander F ^b,c  

^a Harvard University   (United States)

^b HARVARD UNIVERSITY   (United States)

^c HARVARD STEM CELL INSTITUTE   (United States)

^d BROAD INSTITUTE OF MIT AND HARVARD   (United States)

^e RIKEN   (Japan)

^f HOSPITAL FOR SICK CHILDREN   (Canada)

^g MEMORIAL SLOAN KETTERING CANCER CENTER   (United States)

Author keywords

Differentiation; Human; Hypothalamus; Mouse; Narcolepsy; Neuropeptide; Pluripotent; Stem cell

Indexed keywords

4 AMINOBUTYRIC ACID; ARGIPRESSIN; CORTICOTROPIN RELEASING FACTOR; DYNORPHIN A; GLIAL FIBRILLARY ACIDIC PROTEIN; GROWTH HORMONE RELEASING FACTOR; KISSPEPTIN; MELANIN CONCENTRATING HORMONE; OREXIN; OXYTOCIN; PENTRAXIN; PROOPIOMELANOCORTIN; PROTEIN KINASE B; TRANSCRIPTION FACTOR; TRANSCRIPTION FACTOR FOXG1; TRANSCRIPTION FACTOR NKX2.1; TRANSCRIPTION FACTOR OTP; TRANSCRIPTION FACTOR RAX; TRANSCRIPTION FACTOR SIM1; TYROSINE 3 MONOOXYGENASE; UNCLASSIFIED DRUG; AGOUTI RELATED PROTEIN; HYPOPHYSIS HORMONE; HYPOTHALAMUS HORMONE; MELANIN; MELANIN-CONCENTRATING HORMONE; NEUROPEPTIDE; PROTIRELIN; SIGNAL PEPTIDE;

ADOLESCENT; ADULT; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; BRAIN CORTEX; CELL AGGREGATION; CELL DEATH; CELL DIFFERENTIATION; CELL DIVISION; CELL POPULATION; CELL STRUCTURE; CELL SURVIVAL; CONTROLLED STUDY; EMBRYONIC STEM CELL; FOREBRAIN; GLIA CELL; HUMAN; HUMAN CELL; HYPOTHALAMUS; IN VITRO STUDY; MOUSE; NERVE CELL; NERVE FIBER; NEURAL STEM CELL; NEUROEPITHELIUM; NEUROPEPTIDERGIC HYPOTHALAMIC NEURON; NONHUMAN; PLURIPOTENT STEM CELL; PRIORITY JOURNAL; PROTEIN EXPRESSION; RHOMBENCEPHALON; TELENCEPHALON; XENOTRANSPLANTATION; CYTOLOGY; METABOLISM;

AGOUTI-RELATED PROTEIN; ARGININE VASOPRESSIN; HUMANS; HYPOTHALAMIC HORMONES; HYPOTHALAMUS; INTRACELLULAR SIGNALING PEPTIDES AND PROTEINS; MELANINS; NEURONS; NEUROPEPTIDES; OREXINS; OXYTOCIN; PITUITARY HORMONES; PLURIPOTENT STEM CELLS; PRO-OPIOMELANOCORTIN; THYROTROPIN-RELEASING HORMONE;

EID: 84922571348     PISSN: 09501991     EISSN: 14779129     Source Type: Journal    
DOI: 10.1242/dev.117978     Document Type: Article

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