Chylomicron remnant model emulsions induce intracellular cholesterol accumulation and cell death due to lysosomal destabilization

Biochimica et Biophysica Acta - Molecular and Cell Biology of Lipids

Volumn 1851, Issue 5, 2015, Pages 598-604

  Wakita, Kyoko ^a   Morita, Shin Ya ^b   Okamoto, Naoko ^a   Takata, Eriko ^a   Handa, Tetsurou ^c   Nakano, Minoru ^d  

^a KYOTO UNIVERSITY   (Japan)

^b SHIGA UNIVERSITY OF MEDICAL SCIENCE HOSPITAL   (Japan)

^c SUZUKA UNIVERSITY OF MEDICAL SCIENCE   (Japan)

^d UNIVERSITY OF TOYAMA   (Japan)

Author keywords

ac LDL; Apolipoprotein E; Cathepsin L; J774 macrophages

Indexed keywords

APOLIPOPROTEIN A1; CASPASE 3; CATHEPSIN L; CHOLESTEROL; CHYLOMICRON REMNANT; LOW DENSITY LIPOPROTEIN; PROTEINASE; ACETYL-LDL; EMULSION; PHOSPHATIDYLCHOLINE; TRIOLEIN;

ACETYLATION; ARTICLE; CELL DEATH; CELL VIABILITY; CELLULAR DISTRIBUTION; CONTROLLED STUDY; CYTOTOXICITY; EMULSION; ENZYME ACTIVITY; IN VITRO STUDY; LYSOSOME; MACROPHAGE; PRIORITY JOURNAL; ANIMAL; CELL LINE; COMPARATIVE STUDY; METABOLISM; MOUSE; PATHOLOGY; TRANSPORT AT THE CELLULAR LEVEL;

ANIMALS; BIOLOGICAL TRANSPORT; CELL DEATH; CELL LINE; CHOLESTEROL; CHYLOMICRON REMNANTS; EMULSIONS; LIPOPROTEINS, LDL; LYSOSOMES; MACROPHAGES; MICE; PHOSPHATIDYLCHOLINES; TRIOLEIN;

EID: 84922561993     PISSN: 13881981     EISSN: 18792618     Source Type: Journal    
DOI: 10.1016/j.bbalip.2015.01.015     Document Type: Article

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