Free Cholesterol Loading of Macrophages Is Associated with Widespread Mitochondrial Dysfunction and Activation of the Mitochondrial Apoptosis Pathway

Journal of Biological Chemistry

Volumn 276, Issue 45, 2001, Pages 42468-42476

  Yao, Pin Mei ^b   Tabas, Ira ^a  

^a Och Spine at New York Presbyterian Hospitals   (United States)

^b NONE

Author keywords

[No Author keywords available]

Indexed keywords

CHOLESTEROL; CYTOLOGY; ENZYMES;

MACROPHAGES;

BIOCHEMISTRY;

7 OXOCHOLESTEROL; CASPASE 9; CHOLESTEROL; CYTOCHROME C; GLUTATHIONE; PROTEIN BAX; BAX PROTEIN, MOUSE; CASP9 PROTEIN, MOUSE; CASPASE; FAS ANTIGEN; ONCOPROTEIN; PROTEIN BCL 2;

ANIMAL CELL; APOPTOSIS; ARTICLE; ATHEROSCLEROSIS; ATHEROSCLEROTIC PLAQUE; BLOOD VESSEL OCCLUSION; CELL DEATH; CONTROLLED STUDY; DISORDERS OF MITOCHONDRIAL FUNCTIONS; ENZYME ACTIVATION; MACROPHAGE; MEMBRANE POTENTIAL; MITOCHONDRIAL MEMBRANE; MOUSE; NONHUMAN; PERITONEUM MACROPHAGE; PRIORITY JOURNAL; ANIMAL; ARTERIOSCLEROSIS; BIOSYNTHESIS; C57BL MOUSE; DRUG EFFECT; MITOCHONDRION; PATHOLOGY; PHYSIOLOGY; SECRETION;

ANIMALIA;

ANIMALS; ANTIGENS, CD95; APOPTOSIS; ARTERIOSCLEROSIS; BCL-2-ASSOCIATED X PROTEIN; CASPASE 9; CASPASES; CHOLESTEROL; CYTOCHROME C GROUP; GLUTATHIONE; MACROPHAGES; MICE; MICE, INBRED C57BL; MITOCHONDRIA; PROTO-ONCOGENE PROTEINS; PROTO-ONCOGENE PROTEINS C-BCL-2;

EID: 0035834740     PISSN: 00219258     EISSN: None     Source Type: Journal    
DOI: 10.1074/jbc.M101419200     Document Type: Article

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