Influence of chylomicron remnants on human monocyte activation in vitro

Nutrition, Metabolism and Cardiovascular Diseases

Volumn 21, Issue 11, 2011, Pages 871-878

  Bentley, C ^a   Hathaway, N ^a   Widdows, J ^a   Bejta, F ^a   De Pascale, C ^a   Avella, M ^a   Wheeler Jones, C P D ^a   Botham, K M ^a   Lawson, C ^a  

^a ROYAL VETERINARY COLLEGE   (United Kingdom)

Author keywords

Chemokines; Dietary fat; Inflammation; Lipid mediators; Monocytes macrophages

Indexed keywords

CCL2 PROTEIN, HUMAN; CHYLOMICRON REMNANT; INTERLEUKIN 8; MONOCYTE CHEMOTACTIC PROTEIN 1; REACTIVE OXYGEN METABOLITE;

ARTICLE; ATHEROSCLEROSIS; DRUG EFFECT; HUMAN; INFLAMMATION; METABOLISM; MONOCYTE; NEUTROPHIL CHEMOTAXIS; PATHOPHYSIOLOGY; PHYSIOLOGY; SECRETION;

ATHEROSCLEROSIS; CHEMOKINE CCL2; CHEMOTAXIS, LEUKOCYTE; CHYLOMICRON REMNANTS; HUMANS; INFLAMMATION; INTERLEUKIN-8; MONOCYTES; REACTIVE OXYGEN SPECIES;

EID: 80053951951     PISSN: 09394753     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.numecd.2010.02.019     Document Type: Article

References (45)

1. Randolph G.J. The fate of monocytes in atherosclerosis. Journal of Thrombosis and Haemostasis 2009, 7(Suppl. 1):28-30.
2. Saha P., Modarai B., Humphries J., Mattock K., Waltham M., Burnand K.G., et al. The monocyte/macrophage as a therapeutic target in atherosclerosis. Current Opinion in Pharmacology 2009, 9:109-118.
3. Hansson G.K., Libby P. The immune response in atherosclerosis: a double-edged sword. Nature Reviews 2006, 6:508-519.
4. Ross R. Atherosclerosis-an inflammatory disease. The New England Journal of Medicine 1999, 340:115-126.
5. Albertini R., Moratti R., De Luca G. Oxidation of low-density lipoprotein in atherosclerosis from basic biochemistry to clinical studies. Current Molecular Medicine 2002, 2:579-592.
6. Cabezas M.C., de Bruin T.W., Westerveld H.E., Meijer E., Erkelens D.W. Delayed chylomicron remnant clearance in subjects with heterozygous familial hypercholesterolaemia. Journal of Internal Medicine 1998, 244:299-307.
7. Redgrave T.G. Formation and metabolism of chylomicrons. International Review of Physiology 1983, 28:103-130.
8. Grieve D.J., Avella M.A., Elliott J., Botham K.M. The influence of chylomicron remnants on endothelial cell function in the isolated perfused rat aorta. Atherosclerosis 1998, 139:273-281.
9. Proctor S.D., Mamo J.C. Retention of fluorescent-labelled chylomicron remnants within the intima of the arterial wall-evidence that plaque cholesterol may be derived from post-prandial lipoproteins. European Journal of Clinical Investigation 1998, 28:497-503.
10. Mamo J.C., Proctor S.D., Smith D. Retention of chylomicron remnants by arterial tissue; importance of an efficient clearance mechanism from plasma. Atherosclerosis 1998, 141(Suppl. 1):S63-S69.
11. Proctor S.D., Mamo J.C. Arterial fatty lesions have increased uptake of chylomicron remnants but not low-density lipoproteins. Coronary Artery Disease 1996, 7:239-245.
12. Annuzzi G., De Natale C., Iovine C., Patti L., Di Marino L., Coppola S., et al. Insulin resistance is independently associated with postprandial alterations of triglyceride-rich lipoproteins in type 2 diabetes mellitus. Arteriosclerosis, Thrombosis, and Vascular Biology 2004, 24:2397-2402.
13. Ginsberg H.N., Illingworth D.R. Postprandial dyslipidemia: an atherogenic disorder common in patients with diabetes mellitus. The American Journal of Cardiology 2001, 88:9H-15H.
14. Batt K.V., Avella M., Moore E.H., Jackson B., Suckling K.E., Botham K.M. Differential effects of low-density lipoprotein and chylomicron remnants on lipid accumulation in human macrophages. Experimental Biology and Medicine (Maywood, NJ) 2004, 229:528-537.
15. Napolitano M., Bravo E. Evidence of dual pathways for lipid uptake during chylomicron remnant-like particle processing by human macrophages. Journal of Vascular Research 2006, 43:355-366.
16. De Pascale C., Avella M., Perona J.S., Ruiz-Gutierrez V., Wheeler-Jones C.P., Botham K.M. Fatty acid composition of chylomicron remnant-like particles influences their uptake and induction of lipid accumulation in macrophages. The FEBS Journal 2006, 273:5632-5640.
17. Batt K.V., Patel L., Botham K.M., Suckling K.E. Chylomicron remnants and oxidised low density lipoprotein have differential effects on the expression of mRNA for genes involved in human macrophage foam cell formation. Journal of Molecular Medicine (Berlin, Germany) 2004, 82:449-458.
18. De Pascale C., Graham V., Fowkes R.C., Wheeler-Jones C.P., Botham K.M. Suppression of nuclear factor-kappaB activity in macrophages by chylomicron remnants: modulation by the fatty acid composition of the particles. The FEBS Journal 2009, 276:5689-5702.
19. Okumura T., Fujioka Y., Morimoto S., Masai M., Sakoda T., Tsujino T., et al. Chylomicron remnants stimulate release of interleukin-1beta by THP-1 cells. Journal of Atherosclerosis and Thrombosis 2006, 13:38-45.
20. Goulter A.B., Avella M.A., Elliott J., Botham K.M. Chylomicron-remnant-like particles inhibit receptor-mediated endothelium-dependent vasorelaxation in pig coronary arteries. Clinical Science (London) 2002, 103:451-460.
21. Grieve D.J., Avella M.A., Botham K.M., Elliott J. Effects of chylomicrons and chylomicron remnants on endothelium-dependent relaxation of rat aorta. European Journal of Pharmacology 1998, 348:181-190.
22. Botham K.M., Bravo E., Elliott J., Wheeler-Jones C.P. Direct interaction of dietary lipids carried in chylomicron remnants with cells of the artery wall: implications for atherosclerosis development. Current Pharmaceutical Design 2005, 11:3681-3695.
23. Alipour A., van Oostrom A.J., Izraeljan A., Verseyden C., Collins J.M., Frayn K.N., et al. Leukocyte activation by triglyceride-rich lipoproteins. Arteriosclerosis, Thrombosis, and Vascular Biology 2008, 28:792-797.
24. van Oostrom A.J., Rabelink T.J., Verseyden C., Sijmonsma T.P., Plokker H.W., De Jaegere P.P., et al. Activation of leukocytes by postprandial lipemia in healthy volunteers. Atherosclerosis 2004, 177:175-182.
25. Wintergerst E.S., Jelk J., Rahner C., Asmis R. Apoptosis induced by oxidized low density lipoprotein in human monocyte-derived macrophages involves CD36 and activation of caspase-3. European Journal of Biochemistry/FEBS 2000, 267:6050-6059.
26. Bentley C., Bejta F., De Pascale C., Avella M., Wheeler-Jones C.P., Botham K.M., et al. Dietary fats induce human monocyte activation in vitro. Biochemical Society Transactions 2007, 35:464-465.
27. Diard P., Malewiak M.I., Lagrange D., Griglio S. Hepatic lipase may act as a ligand in the uptake of artificial chylomicron remnant-like particles by isolated rat hepatocytes. The Biochemical Journal 1994, 299(Pt 3):889-894.
28. Ginsberg H.N., Zhang Y.L., Hernandez-Ono A. Regulation of plasma triglycerides in insulin resistance and diabetes. Archives of Medical Research 2005, 36:232-240.
29. Napolitano M., Rivabene R., Avella M., Botham K.M., Bravo E. The internal redox balance of the cells influences the metabolism of lipids of dietary origin by J774 macrophages: implications for foam cell formation. Journal of Vascular Research 2001, 38:350-360.
30. Kamemura K., Fujioka Y., Takaishi H., Takahashi A., Taniguchi T., Ishikawa Y., et al. Chylomicron remnants upregulate CD40 expression via the ERK pathway and a redox-sensitive mechanism in THP-1 cells. Atherosclerosis 2006, 187:257-264.
31. Lubos E., Handy D.E., Loscalzo J. Role of oxidative stress and nitric oxide in atherothrombosis. Frontiers in Bioscience 2008, 13:5323-5344.
32. Cuzzocrea S., Chatterjee P.K., Mazzon E., Dugo L., Serraino I., Britti D., et al. Pyrrolidine dithiocarbamate attenuates the development of acute and chronic inflammation. British Journal of Pharmacology 2002, 135:496-510.
33. Hayakawa M., Miyashita H., Sakamoto I., Kitagawa M., Tanaka H., Yasuda H., et al. Evidence that reactive oxygen species do not mediate NF-kappaB activation. The EMBO Journal 2003, 22:3356-3366.
34. Brennan P., O'Neill L.A. 2-mercaptoethanol restores the ability of nuclear factor kappa B (NF kappa B) to bind DNA in nuclear extracts from interleukin 1-treated cells incubated with pyrollidine dithiocarbamate (PDTC). Evidence for oxidation of glutathione in the mechanism of inhibition of NF kappa B by PDTC. The Biochemical Journal 1996, 320(Pt 3):975-981.
35. Bellido C., Lopez-Miranda J., Blanco-Colio L.M., Perez-Martinez P., Muriana F.J., Martin-Ventura J.L., et al. Butter and walnuts, but not olive oil, elicit postprandial activation of nuclear transcription factor kappaB in peripheral blood mononuclear cells from healthy men. The American Journal of Clinical Nutrition 2004, 80:1487-1491.
36. Vignais P.V. The superoxide-generating NADPH oxidase: structural aspects and activation mechanism. Cellular and Molecular Life Sciences 2002, 59:1428-1459.
37. Cave A.C., Brewer A.C., Narayanapanicker A., Ray R., Grieve D.J., Walker S., et al. NADPH oxidases in cardiovascular health and disease. Antioxidants & Redox Signaling 2006, 8:691-728.
38. Gauss K.A., Nelson-Overton L.K., Siemsen D.W., Gao Y., DeLeo F.R., Quinn M.T. Role of NF-kappaB in transcriptional regulation of the phagocyte NADPH oxidase by tumor necrosis factor-alpha. Journal of Leukocyte Biology 2007, 82:729-741.
39. Barbieri S.S., Cavalca V., Eligini S., Brambilla M., Caiani A., Tremoli E., et al. Apocynin prevents cyclooxygenase 2 expression in human monocytes through NADPH oxidase and glutathione redox-dependent mechanisms. Free Radical Biology & Medicine 2004, 37:156-165.
40. Wang Y., Zeigler M.M., Lam G.K., Hunter M.G., Eubank T.D., Khramtsov V.V., et al. The role of the NADPH oxidase complex, p38 MAPK, and Akt in regulating human monocyte/macrophage survival. American Journal of Respiratory Cell and Molecular Biology 2007, 36:68-77.
41. Xie L., Chang L., Guan Y., Wang X. C-reactive protein augments interleukin-8 secretion in human peripheral blood monocytes. Journal of Cardiovascular Pharmacology 2005, 46:690-696.
42. Takao S., Smith E.H., Wang D., Chan C.K., Bulkley G.B., Klein A.S. Role of reactive oxygen metabolites in murine peritoneal macrophage phagocytosis and phagocytic killing. The American Journal of Physiology 1996, 271:C1278-C1284.
43. Domoto K., Taniguchi T., Takaishi H., Takahashi T., Fujioka Y., Takahashi A., et al. Chylomicron remnants induce monocyte chemoattractant protein-1 expression via p38 MAPK activation in vascular smooth muscle cells. Atherosclerosis 2003, 171:193-200.
44. Carluccio M.A., Ancora M.A., Massaro M., Carluccio M., Scoditti E., Distante A., et al. Homocysteine induces VCAM-1 gene expression through NF-kappaB and NAD(P)H oxidase activation: protective role of Mediterranean diet polyphenolic antioxidants. American Journal of Physiology 2007, 293:H2344-H2354.
45. Gerszten R.E., Garcia-Zepeda E.A., Lim Y.C., Yoshida M., Ding H.A., Gimbrone M.A., et al. MCP-1 and IL-8 trigger firm adhesion of monocytes to vascular endothelium under flow conditions. Nature 1999, 398:718-723.