E3 ubiquitin ligase Cbl-b regulates thymic-derived CD4+CD25+ regulatory T cell development by targeting Foxp3 for ubiquitination

Journal of Immunology

Volumn 194, Issue 4, 2015, Pages 1639-1645

  Zhao, Yixia ^a   Guo, Hui ^a   Qiao, Guilin ^a,b   Zucker, Mark ^a   Langdon, Wallace Y ^c   Zhang, Jian ^a,b  

^a OHIO STATE UNIVERSITY   (United States)

^b UNIVERSITY OF CHICAGO   (United States)

^c UNIVERSITY OF WESTERN AUSTRALIA   (Australia)

Author keywords

[No Author keywords available]

Indexed keywords

CASITAS B LINEAGE LYMPHOMA PROTEIN B; INTERLEUKIN 2; PROTEASOME; STUB1 PROTEIN; TRANSCRIPTION FACTOR FOXP3; UBIQUITIN PROTEIN LIGASE; UBIQUITIN PROTEIN LIGASE E3; UNCLASSIFIED DRUG; CBL PROTEIN; CBLB PROTEIN, MOUSE; CHIP PROTEIN, MOUSE; FORKHEAD TRANSCRIPTION FACTOR; FOXP3 PROTEIN, MOUSE; SIGNAL TRANSDUCING ADAPTOR PROTEIN;

ANIMAL CELL; ANIMAL EXPERIMENT; ARTICLE; BINDING AFFINITY; CD4+ CD25+ T LYMPHOCYTE; CELL MATURATION; CONTROLLED STUDY; CYTOKINE PRODUCTION; ENZYME ACTIVITY; ENZYME DEGRADATION; LYMPHOCYTE ACTIVATION; MOUSE; NONHUMAN; PROTEIN EXPRESSION; PROTEIN PROTEIN INTERACTION; REGULATORY T LYMPHOCYTE; UBIQUITINATION; ANIMAL; BAGG ALBINO MOUSE; C57BL MOUSE; CYTOLOGY; GENETIC TRANSFECTION; IMMUNOLOGY; KNOCKOUT MOUSE; METABOLISM; THYMUS;

ADAPTOR PROTEINS, SIGNAL TRANSDUCING; ANIMALS; FORKHEAD TRANSCRIPTION FACTORS; LYMPHOCYTE ACTIVATION; MICE; MICE, INBRED BALB C; MICE, INBRED C57BL; MICE, KNOCKOUT; PROTO-ONCOGENE PROTEINS C-CBL; T-LYMPHOCYTES, REGULATORY; THYMUS GLAND; TRANSFECTION; UBIQUITIN-PROTEIN LIGASES; UBIQUITINATION;

EID: 84922551915     PISSN: 00221767     EISSN: 15506606     Source Type: Journal    
DOI: 10.4049/jimmunol.1402434     Document Type: Article

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