Cbl-b-dependent Coordinated Degradation of the Epidermal Growth Factor Receptor Signaling Complex

Journal of Biological Chemistry

Volumn 276, Issue 29, 2001, Pages 27677-27684

  Ettenberg, Seth A ^a,b   Magnifico, Alessandra ^a   Cuello, Mauricio ^a   Nau, Marion M ^a   Rubinstein, Yaffa R ^a   Yarden, Yosef ^c   Weissman, Allan M ^a   Lipkowitz, Stan ^a,b  

^a NATIONAL CANCER INSTITUTE   (United States)

^b UNIFORMED SERVICES UNIVERSITY OF THE HEALTH SCIENCES   (United States)

^c WEIZMANN INSTITUTE OF SCIENCE   (Israel)

Author keywords

[No Author keywords available]

Indexed keywords

AMINO ACIDS; DEGRADATION; ENZYMES; GROWTH KINETICS;

EPIDERMAL GROWTH FACTORS (EGF);

BIOCHEMISTRY;

EPIDERMAL GROWTH FACTOR RECEPTOR; PROTEIN CBL B; PROTEIN TYROSINE KINASE; REGULATOR PROTEIN; UNCLASSIFIED DRUG; CARRIER PROTEIN; CBL PROTEIN; CBLB PROTEIN, HUMAN; PHOSPHOPROTEIN; SIGNAL TRANSDUCING ADAPTOR PROTEIN; UBIQUITIN; UBIQUITIN PROTEIN LIGASE;

ARTICLE; BINDING KINETICS; BINDING SITE; CONTROLLED STUDY; DOWN REGULATION; ENZYME ACTIVITY; HUMAN; HUMAN CELL; IMMUNOPRECIPITATION; PRIORITY JOURNAL; PROTEIN DEGRADATION; PROTEIN EXPRESSION; REGULATORY MECHANISM; SIGNAL TRANSDUCTION; STRUCTURE ANALYSIS; CELL CULTURE; CHEMISTRY; HYDROLYSIS; METABOLISM; PHYSIOLOGY; PROTEIN CONFORMATION;

ADAPTOR PROTEINS, SIGNAL TRANSDUCING; CARRIER PROTEINS; HUMANS; HYDROLYSIS; PHOSPHOPROTEINS; PROTEIN CONFORMATION; PROTO-ONCOGENE PROTEINS C-CBL; RECEPTOR, EPIDERMAL GROWTH FACTOR; SIGNAL TRANSDUCTION; TUMOR CELLS, CULTURED; UBIQUITIN-PROTEIN LIGASES; UBIQUITINS;

EID: 0035920225     PISSN: 00219258     EISSN: None     Source Type: Journal    
DOI: 10.1074/jbc.M102641200     Document Type: Article

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