E3 Ubiquitin Ligase Cbl-b Regulates Pten via Nedd4 in T Cells Independently of Its Ubiquitin Ligase Activity

Cell Reports

Volumn 1, Issue 5, 2012, Pages 472-482

  Guo, Hui ^a   Qiao, Guilin ^a   Ying, Haiyan ^a   Li, Zhenping ^a   Zhao, Yixia ^a   Liang, Yanran ^a   Yang, Lifen ^a   Lipkowitz, Stanley ^b   Penninger, Josef M ^c   Langdon, Wallace Y ^d   Zhang, Jian ^a  

^a UNIVERSITY OF CHICAGO   (United States)

^b NATIONAL CANCER INSTITUTE   (United States)

^c ERICH SCHMID INSTITUTE OF MATERIALS SCIENCE   (Austria)

^d UNIVERSITY OF WESTERN AUSTRALIA   (Australia)

Author keywords

[No Author keywords available]

Indexed keywords

CBL B PROTEIN; CD28 ANTIGEN; LIGASE; PHOSPHATIDYLINOSITOL 3 KINASE; PHOSPHATIDYLINOSITOL 3,4,5 TRISPHOSPHATE 3 PHOSPHATASE; PROTEIN KINASE B; T LYMPHOCYTE RECEPTOR; UBIQUITIN PROTEIN LIGASE NEDD4; UNCLASSIFIED DRUG;

ANIMAL CELL; ARTICLE; BIOACCUMULATION; CONTROLLED STUDY; EMBRYO; ENZYME ACTIVATION; ENZYME ACTIVITY; ENZYME INACTIVATION; ENZYME INHIBITION; ENZYME REGULATION; FETUS; MOUSE; NONHUMAN; PROTEIN PROTEIN INTERACTION; T LYMPHOCYTE; UBIQUITINATION;

ADAPTOR PROTEINS, SIGNAL TRANSDUCING; ANIMALS; ANTIGENS, CD28; ENDOSOMAL SORTING COMPLEXES REQUIRED FOR TRANSPORT; FEMALE; LYMPHOCYTE ACTIVATION; MALE; MICE; MICE, INBRED BALB C; MICE, KNOCKOUT; MODELS, ANIMAL; MOLECULAR SEQUENCE DATA; PHOSPHATIDYLINOSITOL 3-KINASES; PROTO-ONCOGENE PROTEINS C-AKT; PROTO-ONCOGENE PROTEINS C-CBL; PTEN PHOSPHOHYDROLASE; RECEPTORS, ANTIGEN, T-CELL; SIGNAL TRANSDUCTION; T-LYMPHOCYTES; UBIQUITIN-PROTEIN LIGASES;

MUS;

EID: 84861716323     PISSN: None     EISSN: 22111247     Source Type: Journal    
DOI: 10.1016/j.celrep.2012.04.008     Document Type: Article

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