Wnt5a and Wnt11 inhibit the canonical Wnt pathway and promote cardiac progenitor development via the Caspase-dependent degradation of AKT

Developmental Biology

Volumn 398, Issue 1, 2015, Pages 80-96

  Bisson, Joseph A ^a   Mills, Bradley ^a   Helt, Jay Christian Paul ^a   Zwaka, Thomas P ^b   Cohen, Ethan David ^a  

^a UNIVERSITY OF ROCHESTER SCHOOL OF MEDICINE AND DENTISTRY   (United States)

^b MOUNT SINAI SCHOOL OF MEDICINE   (United States)

Author keywords

Akt; Cardiac progenitor cell; Caspase; Heart; Wnt signaling; Catenin

Indexed keywords

BETA CATENIN; CASPASE; CASPASE 3; CASPASE INHIBITOR; PHOSPHATIDYLINOSITOL 3 KINASE; PROTEIN KINASE B; WNT11 PROTEIN; WNT5A PROTEIN; AKT1 PROTEIN, MOUSE; WNT PROTEIN; WNT11 PROTEIN, MOUSE; WNT5A PROTEIN, MOUSE;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL TISSUE; APOPTOSIS; ARTICLE; CELL DIFFERENTIATION; CELL MATURATION; CELL MUTANT; CONTROLLED STUDY; EMBRYO; EMBRYO DEVELOPMENT; EMBRYONIC STEM CELL; ENZYME ACTIVATION; ENZYME ACTIVITY; ENZYME DEGRADATION; ENZYME INHIBITION; ENZYME PHOSPHORYLATION; FEMALE; GENE EXPRESSION; HEART DEVELOPMENT; HEART MUSCLE CELL; MOUSE; NONHUMAN; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN PHOSPHORYLATION; PROTEIN PROTEIN INTERACTION; SECOND HEART FIELD PROGENITOR CELL; SIGNAL TRANSDUCTION; STEM CELL; ANIMAL; BREEDING; CELL LINE; CYTOLOGY; EMBRYOLOGY; GENE EXPRESSION REGULATION; HEART; HEART MUSCLE; MALE; METABOLISM; MUTATION; PHOSPHORYLATION; PHYSIOLOGY; POLYMERASE CHAIN REACTION; PREGNANCY; TRANSGENIC MOUSE; WNT SIGNALING PATHWAY;

MUS;

ANIMALS; CASPASES; CELL LINE; EMBRYONIC STEM CELLS; FEMALE; GENE EXPRESSION REGULATION, DEVELOPMENTAL; HEART; MALE; MICE; MICE, TRANSGENIC; MUTATION; MYOCARDIUM; PHOSPHORYLATION; POLYMERASE CHAIN REACTION; PREGNANCY; PREGNANCY, ANIMAL; PROTO-ONCOGENE PROTEINS C-AKT; SIGNAL TRANSDUCTION; STEM CELLS; WNT PROTEINS; WNT SIGNALING PATHWAY;

EID: 84922530317     PISSN: 00121606     EISSN: 1095564X     Source Type: Journal    
DOI: 10.1016/j.ydbio.2014.11.015     Document Type: Article

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