-
1
-
-
12344271332
-
On the catalytic mechanism of choline oxidase
-
Fan, F. and Gadda, G. (2005) On the catalytic mechanism of choline oxidase J. Am. Chem. Soc. 127, 2067-2074
-
(2005)
J. Am. Chem. Soc.
, vol.127
, pp. 2067-2074
-
-
Fan, F.1
Gadda, G.2
-
2
-
-
32444447830
-
Mechanistic studies of choline oxidase with betaine aldehyde and its isosteric analogue 3,3-dimethylbutyraldehyde
-
Fan, F., Germann, M. W., and Gadda, G. (2006) Mechanistic studies of choline oxidase with betaine aldehyde and its isosteric analogue 3,3-dimethylbutyraldehyde Biochemistry 45, 1979-1986
-
(2006)
Biochemistry
, vol.45
, pp. 1979-1986
-
-
Fan, F.1
Germann, M.W.2
Gadda, G.3
-
3
-
-
84874032081
-
Relative timing of hydrogen and proton transfers in the reaction of flavin oxidation catalyzed by choline oxidase
-
Gannavaram, S. and Gadda, G. (2013) Relative timing of hydrogen and proton transfers in the reaction of flavin oxidation catalyzed by choline oxidase Biochemistry 52, 1221-1226
-
(2013)
Biochemistry
, vol.52
, pp. 1221-1226
-
-
Gannavaram, S.1
Gadda, G.2
-
4
-
-
70350050563
-
The cluster of hydrophobic residues controls the entrance to the active site of choline oxidase
-
Xin, Y., Gadda, G., and Hamelberg, D. (2009) The cluster of hydrophobic residues controls the entrance to the active site of choline oxidase Biochemistry 48, 9599-9605
-
(2009)
Biochemistry
, vol.48
, pp. 9599-9605
-
-
Xin, Y.1
Gadda, G.2
Hamelberg, D.3
-
5
-
-
67650541861
-
Contribution of flavin covalent linkage with histidine 99 to the reaction catalyzed by choline oxidase
-
Quaye, O., Cowins, S., and Gadda, G. (2009) Contribution of flavin covalent linkage with histidine 99 to the reaction catalyzed by choline oxidase J. Biol. Chem. 284, 16990-16997
-
(2009)
J. Biol. Chem.
, vol.284
, pp. 16990-16997
-
-
Quaye, O.1
Cowins, S.2
Gadda, G.3
-
6
-
-
84894127458
-
Structure of choline oxidase in complex with the reaction product glycine betaine
-
50070
-
Salvi, F., Wang, Y. F., Weber, I. T., and Gadda, G. (2014) Structure of choline oxidase in complex with the reaction product glycine betaine Acta Crystallogr. D 70, 405-413
-
(2014)
Acta Crystallogr.
, pp. 405-413
-
-
Salvi, F.1
Wang, Y.F.2
Weber, I.T.3
Gadda, G.4
-
7
-
-
58849100936
-
Hydride transfer made easy in the reaction of alcohol oxidation catalyzed by flavin-dependent oxidases
-
Gadda, G. (2008) Hydride transfer made easy in the reaction of alcohol oxidation catalyzed by flavin-dependent oxidases Biochemistry 47, 13745-13753
-
(2008)
Biochemistry
, vol.47
, pp. 13745-13753
-
-
Gadda, G.1
-
8
-
-
37849031214
-
Role of Glu312 in binding and positioning of the substrate for the hydride transfer reaction in choline oxidase
-
Quaye, O., Lountos, G. T., Fan, F., Orville, A. M., and Gadda, G. (2008) Role of Glu312 in binding and positioning of the substrate for the hydride transfer reaction in choline oxidase Biochemistry 47, 243-256
-
(2008)
Biochemistry
, vol.47
, pp. 243-256
-
-
Quaye, O.1
Lountos, G.T.2
Fan, F.3
Orville, A.M.4
Gadda, G.5
-
9
-
-
29344449107
-
Oxygen- and temperature-dependent kinetic isotope effects in choline oxidase: Correlating reversible hydride transfer with environmentally enhanced tunneling
-
Fan, F. and Gadda, G. (2005) Oxygen- and temperature-dependent kinetic isotope effects in choline oxidase: Correlating reversible hydride transfer with environmentally enhanced tunneling J. Am. Chem. Soc. 127, 17954-17961
-
(2005)
J. Am. Chem. Soc.
, vol.127
, pp. 17954-17961
-
-
Fan, F.1
Gadda, G.2
-
10
-
-
69849104100
-
Effect of a conservative mutation of an active site residue involved in substrate binding on the hydride tunneling reaction catalyzed by choline oxidase
-
Quaye, O. and Gadda, G. (2009) Effect of a conservative mutation of an active site residue involved in substrate binding on the hydride tunneling reaction catalyzed by choline oxidase Arch. Biochem. Biophys. 489, 10-14
-
(2009)
Arch. Biochem. Biophys.
, vol.489
, pp. 10-14
-
-
Quaye, O.1
Gadda, G.2
-
11
-
-
34249676309
-
An internal equilibrium preorganizes the enzyme-substrate complex for hydride tunneling in choline oxidase
-
Fan, F. and Gadda, G. (2007) An internal equilibrium preorganizes the enzyme-substrate complex for hydride tunneling in choline oxidase Biochemistry 46, 6402-6408
-
(2007)
Biochemistry
, vol.46
, pp. 6402-6408
-
-
Fan, F.1
Gadda, G.2
-
12
-
-
79952094721
-
Importance of a serine proximal to the C(4a) and N(5) flavin atoms for hydride transfer in choline oxidase
-
Yuan, H. and Gadda, G. (2011) Importance of a serine proximal to the C(4a) and N(5) flavin atoms for hydride transfer in choline oxidase Biochemistry 50, 770-779
-
(2011)
Biochemistry
, vol.50
, pp. 770-779
-
-
Yuan, H.1
Gadda, G.2
-
13
-
-
46049114878
-
On the role of histidine 351 in the reaction of alcohol oxidation catalyzed by choline oxidase
-
Rungsrisuriyachai, K. and Gadda, G. (2008) On the role of histidine 351 in the reaction of alcohol oxidation catalyzed by choline oxidase Biochemistry 47, 6762-6769
-
(2008)
Biochemistry
, vol.47
, pp. 6762-6769
-
-
Rungsrisuriyachai, K.1
Gadda, G.2
-
14
-
-
77949505450
-
Role of asparagine 510 in the relative timing of substrate bond cleavages in the reaction catalyzed by choline oxidase
-
Rungsrisuriyachai, K. and Gadda, G. (2010) Role of asparagine 510 in the relative timing of substrate bond cleavages in the reaction catalyzed by choline oxidase Biochemistry 49, 2483-2490
-
(2010)
Biochemistry
, vol.49
, pp. 2483-2490
-
-
Rungsrisuriyachai, K.1
Gadda, G.2
-
15
-
-
12344251747
-
On the catalytic role of the conserved active site residue His466 of choline oxidase
-
Ghanem, M. and Gadda, G. (2005) On the catalytic role of the conserved active site residue His466 of choline oxidase Biochemistry 44, 893-904
-
(2005)
Biochemistry
, vol.44
, pp. 893-904
-
-
Ghanem, M.1
Gadda, G.2
-
16
-
-
79956001462
-
Substrate diffusion and oxidation in GMC oxidoreductases: An experimental and computational study on fungal aryl-alcohol oxidase
-
Hernandez-Ortega, A., Borrelli, K., Ferreira, P., Medina, M., Martinez, A. T., and Guallar, V. (2011) Substrate diffusion and oxidation in GMC oxidoreductases: An experimental and computational study on fungal aryl-alcohol oxidase Biochem. J. 436, 341-350
-
(2011)
Biochem. J.
, vol.436
, pp. 341-350
-
-
Hernandez-Ortega, A.1
Borrelli, K.2
Ferreira, P.3
Medina, M.4
Martinez, A.T.5
Guallar, V.6
-
17
-
-
81555196346
-
Identification of a catalytic base for sugar oxidation in the pyranose 2-oxidase reaction
-
Wongnate, T., Sucharitakul, J., and Chaiyen, P. (2011) Identification of a catalytic base for sugar oxidation in the pyranose 2-oxidase reaction ChemBioChem 12, 2577-2586
-
(2011)
ChemBioChem
, vol.12
, pp. 2577-2586
-
-
Wongnate, T.1
Sucharitakul, J.2
Chaiyen, P.3
-
18
-
-
0037446732
-
Role of the flavin domain residues, His689 and Asn732, in the catalytic mechanism of cellobiose dehydrogenase from phanerochaete chrysosporium
-
Rotsaert, F. A., Renganathan, V., and Gold, M. H. (2003) Role of the flavin domain residues, His689 and Asn732, in the catalytic mechanism of cellobiose dehydrogenase from phanerochaete chrysosporium Biochemistry 42, 4049-4056
-
(2003)
Biochemistry
, vol.42
, pp. 4049-4056
-
-
Rotsaert, F.A.1
Renganathan, V.2
Gold, M.H.3
-
19
-
-
84879230778
-
The substrate oxidation mechanism of pyranose 2-oxidase and other related enzymes in the glucose-methanol-choline superfamily
-
Wongnate, T. and Chaiyen, P. (2013) The substrate oxidation mechanism of pyranose 2-oxidase and other related enzymes in the glucose-methanol-choline superfamily FEBS J. 280, 3009-3027
-
(2013)
FEBS J.
, vol.280
, pp. 3009-3027
-
-
Wongnate, T.1
Chaiyen, P.2
-
20
-
-
84922417266
-
Alcohol oxidation of flavoenzymes
-
Romero, E. and Gadda, G. (2014) Alcohol oxidation of flavoenzymes Biomol. Concepts 5, 299-318
-
(2014)
Biomol. Concepts
, vol.5
, pp. 299-318
-
-
Romero, E.1
Gadda, G.2
-
21
-
-
84865428476
-
Role of active site histidines in the two half-reactions of the aryl-alcohol oxidase catalytic cycle
-
Hernandez-Ortega, A., Lucas, F., Ferreira, P., Medina, M., Guallar, V., and Martinez, A. T. (2012) Role of active site histidines in the two half-reactions of the aryl-alcohol oxidase catalytic cycle Biochemistry 51, 6595-6608
-
(2012)
Biochemistry
, vol.51
, pp. 6595-6608
-
-
Hernandez-Ortega, A.1
Lucas, F.2
Ferreira, P.3
Medina, M.4
Guallar, V.5
Martinez, A.T.6
-
22
-
-
33644868234
-
Effects of reversing the protein positive charge in the proximity of the flavin N(1) locus of choline oxidase
-
Ghanem, M. and Gadda, G. (2006) Effects of reversing the protein positive charge in the proximity of the flavin N(1) locus of choline oxidase Biochemistry 45, 3437-3447
-
(2006)
Biochemistry
, vol.45
, pp. 3437-3447
-
-
Ghanem, M.1
Gadda, G.2
-
24
-
-
0000986544
-
The reaction of hydroxylamine with activated acyl groups. II. Mechanism of the reaction
-
Jencks, W. P. (1958) The reaction of hydroxylamine with activated acyl groups. II. Mechanism of the reaction J. Am. Chem. Soc. 80, 4585-4588
-
(1958)
J. Am. Chem. Soc.
, vol.80
, pp. 4585-4588
-
-
Jencks, W.P.1
-
25
-
-
0000373822
-
Reactions of isopropyl methylphosphonofluoridate with substituted phenols. I.
-
Epstein, J., Plapinger, R. E., Michel, H. O., Cable, J. R., Stephani, R. A., Hester, R. J., Billington, C., Jr., and List, G. R. (1964) Reactions of isopropyl methylphosphonofluoridate with substituted phenols. I. J. Am. Chem. Soc. 86, 3075-3084
-
(1964)
J. Am. Chem. Soc.
, vol.86
, pp. 3075-3084
-
-
Epstein, J.1
Plapinger, R.E.2
Michel, H.O.3
Cable, J.R.4
Stephani, R.A.5
Hester, R.J.6
Billington, C.7
List, G.R.8
-
26
-
-
0347594221
-
Spectroscopic and kinetic properties of recombinant choline oxidase from Arthrobacter globiformis
-
Ghanem, M., Fan, F., Francis, K., and Gadda, G. (2003) Spectroscopic and kinetic properties of recombinant choline oxidase from Arthrobacter globiformis Biochemistry 42, 15179-15188
-
(2003)
Biochemistry
, vol.42
, pp. 15179-15188
-
-
Ghanem, M.1
Fan, F.2
Francis, K.3
Gadda, G.4
-
27
-
-
0030758374
-
Glycerol-assisted restorative adjustment of flavoenzyme conformation perturbed by site-directed mutagenesis
-
Raibekas, A. A. and Massey, V. (1997) Glycerol-assisted restorative adjustment of flavoenzyme conformation perturbed by site-directed mutagenesis J. Biol. Chem. 272, 22248-22252
-
(1997)
J. Biol. Chem.
, vol.272
, pp. 22248-22252
-
-
Raibekas, A.A.1
Massey, V.2
-
28
-
-
0029845775
-
Glycerol-induced development of catalytically active conformation of Crotalus adamanteus l -amino acid oxidase in vitro
-
Raibekas, A. A. and Massey, V. (1996) Glycerol-induced development of catalytically active conformation of Crotalus adamanteus l -amino acid oxidase in vitro Proc. Natl. Acad. Sci. U.S.A. 93, 7546-7551
-
(1996)
Proc. Natl. Acad. Sci. U.S.A.
, vol.93
, pp. 7546-7551
-
-
Raibekas, A.A.1
Massey, V.2
-
29
-
-
0000171230
-
A new method for preparing flavin-adenine dinucleotide
-
Whitby, L. G. (1953) A new method for preparing flavin-adenine dinucleotide Biochem. J. 54, 437-442
-
(1953)
Biochem. J.
, vol.54
, pp. 437-442
-
-
Whitby, L.G.1
-
30
-
-
0001909564
-
Improved WATERGATE pulse sequences for solvent suppression in NMR spectroscopy
-
Liu, M. L., Mao, X. A., Ye, C. H., Huang, H., Nicholson, J. K., and Lindon, J. C. (1998) Improved WATERGATE pulse sequences for solvent suppression in NMR spectroscopy J. Magn. Reson. 132, 125-129
-
(1998)
J. Magn. Reson.
, vol.132
, pp. 125-129
-
-
Liu, M.L.1
Mao, X.A.2
Ye, C.H.3
Huang, H.4
Nicholson, J.K.5
Lindon, J.C.6
-
31
-
-
0348109494
-
Cloning, sequence analysis, and purification of choline oxidase from Arthrobacter globiformis: A bacterial enzyme involved in osmotic stress tolerance
-
Fan, F., Ghanem, M., and Gadda, G. (2004) Cloning, sequence analysis, and purification of choline oxidase from Arthrobacter globiformis: A bacterial enzyme involved in osmotic stress tolerance Arch. Biochem. Biophys. 421, 149-158
-
(2004)
Arch. Biochem. Biophys.
, vol.421
, pp. 149-158
-
-
Fan, F.1
Ghanem, M.2
Gadda, G.3
-
32
-
-
77956177377
-
Structural and kinetic studies on the Ser101Ala variant of choline oxidase: Catalysis by compromise
-
Finnegan, S., Yuan, H., Wang, Y. F., Orville, A. M., Weber, I. T., and Gadda, G. (2010) Structural and kinetic studies on the Ser101Ala variant of choline oxidase: Catalysis by compromise Arch. Biochem. Biophys. 501, 207-213
-
(2010)
Arch. Biochem. Biophys.
, vol.501
, pp. 207-213
-
-
Finnegan, S.1
Yuan, H.2
Wang, Y.F.3
Orville, A.M.4
Weber, I.T.5
Gadda, G.6
-
33
-
-
77950407407
-
Role of valine 464 in the flavin oxidation reaction catalyzed by choline oxidase
-
Finnegan, S., Agniswamy, J., Weber, I. T., and Gadda, G. (2010) Role of valine 464 in the flavin oxidation reaction catalyzed by choline oxidase Biochemistry 49, 2952-2961
-
(2010)
Biochemistry
, vol.49
, pp. 2952-2961
-
-
Finnegan, S.1
Agniswamy, J.2
Weber, I.T.3
Gadda, G.4
-
34
-
-
0024533010
-
The temperature and pH dependence of some properties of p -hydroxybenzoate hydroxylase from Pseudomonas fluorescenn
-
van Berkel, W. J. H. and Muller, F. (1989) The temperature and pH dependence of some properties of p -hydroxybenzoate hydroxylase from Pseudomonas fluorescenn Eur. J. Biochem. 179, 307-314
-
(1989)
Eur. J. Biochem.
, vol.179
, pp. 307-314
-
-
Van Berkel, W.J.H.1
Muller, F.2
-
35
-
-
0034584873
-
The use of circular dichroism in the investigation of protein structure and function
-
Kelly, S. M. and Price, N. C. (2000) The use of circular dichroism in the investigation of protein structure and function Curr. Protein Pept. Sci. 1, 349-384
-
(2000)
Curr. Protein Pept. Sci.
, vol.1
, pp. 349-384
-
-
Kelly, S.M.1
Price, N.C.2
-
36
-
-
0018463141
-
A study of flavin-protein and flavoprotein-ligand interactions
-
Shiga, K., Horuke, K., Nishina, Y., Otani, S., Watari, H., and Yamano, T. (1978) A study of flavin-protein and flavoprotein-ligand interactions J. Biochem. 85, 931-941
-
(1978)
J. Biochem.
, vol.85
, pp. 931-941
-
-
Shiga, K.1
Horuke, K.2
Nishina, Y.3
Otani, S.4
Watari, H.5
Yamano, T.6
-
37
-
-
0029062806
-
Changes in secondary structure and flavin microenvironment between Azotobacter vinelandii lipoamide dehydrogenase and several deletion mutants from circular dischroism
-
Visser, A. J. W. G., van Berkel, W. J. H., and de Kok, A. (1995) Changes in secondary structure and flavin microenvironment between Azotobacter vinelandii lipoamide dehydrogenase and several deletion mutants from circular dischroism Biochim. Biophys. Acta 1229, 381-385
-
(1995)
Biochim. Biophys. Acta
, vol.1229
, pp. 381-385
-
-
Visser, A.J.W.G.1
Van Berkel, W.J.H.2
De Kok, A.3
-
39
-
-
0141976293
-
PH and deuterium kinetic isotope effects studies on the oxidation of choline to betaine-aldehyde catalyzed by choline oxidase
-
Gadda, G. (2003) pH and deuterium kinetic isotope effects studies on the oxidation of choline to betaine-aldehyde catalyzed by choline oxidase Biochim. Biophys. Acta 1650, 4-9
-
(2003)
Biochim. Biophys. Acta
, vol.1650
, pp. 4-9
-
-
Gadda, G.1
-
40
-
-
0032584261
-
The enhancement of enzymatic rate accelerations by Bronsted acid-base catalysis
-
Richard, J. P. (1998) The enhancement of enzymatic rate accelerations by Bronsted acid-base catalysis Biochemistry 37, 4305-4309
-
(1998)
Biochemistry
, vol.37
, pp. 4305-4309
-
-
Richard, J.P.1
-
41
-
-
77953727643
-
Rescuing of the hydride transfer reaction in the Glu312Asp variant of choline oxidase by a substrate analogue
-
Quaye, O., Nguyen, T., Gannavaram, S., Pennati, A., and Gadda, G. (2010) Rescuing of the hydride transfer reaction in the Glu312Asp variant of choline oxidase by a substrate analogue Arch. Biochem. Biophys. 499, 1-5
-
(2010)
Arch. Biochem. Biophys.
, vol.499
, pp. 1-5
-
-
Quaye, O.1
Nguyen, T.2
Gannavaram, S.3
Pennati, A.4
Gadda, G.5
-
42
-
-
0018855280
-
Effect of hydrogen bonding on electronic spectra and reactivity of flavins
-
Yagi, K., Ohishi, N., Nishimoto, K., Choi, J. D., and Song, P. S. (1980) Effect of hydrogen bonding on electronic spectra and reactivity of flavins Biochemistry 19, 1553-1557
-
(1980)
Biochemistry
, vol.19
, pp. 1553-1557
-
-
Yagi, K.1
Ohishi, N.2
Nishimoto, K.3
Choi, J.D.4
Song, P.S.5
-
43
-
-
0018786922
-
Synthesis and spectral properties of a hydrophobic fluorescent probe: 6-Propionyl-2-(dimethylamino)naphthalene
-
Weber, G. and Farris, F. J. (1979) Synthesis and spectral properties of a hydrophobic fluorescent probe: 6-Propionyl-2-(dimethylamino)naphthalene Biochemistry 18, 3075-3078
-
(1979)
Biochemistry
, vol.18
, pp. 3075-3078
-
-
Weber, G.1
Farris, F.J.2
-
44
-
-
0014858180
-
Fluorescence properties of flavins in various solvents
-
Kotaki, A. and Yagi, K. (1970) Fluorescence properties of flavins in various solvents J. Biochem. 68, 509-516
-
(1970)
J. Biochem.
, vol.68
, pp. 509-516
-
-
Kotaki, A.1
Yagi, K.2
-
45
-
-
0015210971
-
Circular dichroism studies of the flavin chromophore and of the relation between redox properties and flavin environment in oxidases and dehydrogenases
-
Edmondson, D. E. and Tollin, G. (1971) Circular dichroism studies of the flavin chromophore and of the relation between redox properties and flavin environment in oxidases and dehydrogenases Biochemistry 10, 113-124
-
(1971)
Biochemistry
, vol.10
, pp. 113-124
-
-
Edmondson, D.E.1
Tollin, G.2
-
46
-
-
0030011584
-
Flavinylation in wild-type trimethylamine dehydrogenase and differentially charged mutant enzymes: A study of the protein environment around the N1 of the flavin isoalloxazine
-
Mewies, M., Packman, L. C., Mathews, F. S., and Scrutton, N. S. (1996) Flavinylation in wild-type trimethylamine dehydrogenase and differentially charged mutant enzymes: A study of the protein environment around the N1 of the flavin isoalloxazine Biochem. J. 317 (Part 1) 267-272
-
(1996)
Biochem. J.
, vol.317
, pp. 267-272
-
-
Mewies, M.1
Packman, L.C.2
Mathews, F.S.3
Scrutton, N.S.4
-
47
-
-
0001390566
-
Monomeric sarcosine oxidase: Structure of a covalently flavinylated amine oxidizing enzyme
-
Trickey, P., Wagner, M. A., Jorns, M. S., and Mathews, F. S. (1999) Monomeric sarcosine oxidase: Structure of a covalently flavinylated amine oxidizing enzyme Structure 7, 331-345
-
(1999)
Structure
, vol.7
, pp. 331-345
-
-
Trickey, P.1
Wagner, M.A.2
Jorns, M.S.3
Mathews, F.S.4
-
48
-
-
0042622631
-
Kinetic mechanism of choline oxidase from Arthrobacter globiformis
-
Gadda, G. (2003) Kinetic mechanism of choline oxidase from Arthrobacter globiformis Biochim. Biophys. Acta 1646, 112-118
-
(2003)
Biochim. Biophys. Acta
, vol.1646
, pp. 112-118
-
-
Gadda, G.1
|