Rescuing of the hydride transfer reaction in the Glu312Asp variant of choline oxidase by a substrate analogue

Archives of Biochemistry and Biophysics

Volumn 499, Issue 1-2, 2010, Pages 1-5

  Quaye, Osbourne ^a   Nguyen, Tranbao ^a   Gannavaram, Swathi ^a   Pennati, Andrea ^a   Gadda, Giovanni ^a  

^a GEORGIA STATE UNIVERSITY   (United States)

Author keywords

Choline oxidase; Flavoprotein; Hydride transfer; Oxidase; Reductive half reaction; Substrate analogue

Indexed keywords

3 HYDROXYPROPYL TRIMETHYLAMINE; ALCOHOL; ASPARTIC ACID; CHOLINE OXIDASE; ENZYME VARIANT; GLUTAMINE; HYDROGEN; TRIMETHYLAMINE; UNCLASSIFIED DRUG; ALCOHOL DEHYDROGENASE; CHOLINE; DRUG DERIVATIVE; METHYLAMINE;

ARTICLE; CATALYSIS; CONTROLLED STUDY; ENZYME ACTIVE SITE; ENZYME KINETICS; ENZYME MODIFICATION; ENZYME SUBSTRATE COMPLEX; MOLECULAR INTERACTION; OXIDATION; PRIORITY JOURNAL; PROTON TRANSPORT; STEADY STATE; AMINO ACID SUBSTITUTION; ARTHROBACTER; CHEMISTRY; ENZYME SPECIFICITY; ENZYMOLOGY; GENETIC VARIABILITY; GENETICS; KINETICS; METABOLISM; PH;

ALCOHOL OXIDOREDUCTASES; AMINO ACID SUBSTITUTION; ARTHROBACTER; CATALYTIC DOMAIN; CHOLINE; GENETIC VARIATION; HYDROGEN-ION CONCENTRATION; KINETICS; METHYLAMINES; SUBSTRATE SPECIFICITY;

EID: 77953727643     PISSN: 00039861     EISSN: 10960384     Source Type: Journal    
DOI: 10.1016/j.abb.2010.04.024     Document Type: Article

References (23)

1. Gadda G. Biochemistry 2008, 47:13745-13753.
2. Ikuta S., Imamura S., Misaki H., Horiuti Y. J. Biochem. 1977, 82:1741-1749.
3. Gadda G. Biochim. Biophys. Acta 2003, 1646:112-118.
4. Ghoul M., Bernard T., Cormier M. Appl. Environ. Microbiol. 1990, 56:551-554.
5. Kappes R.M., Kempf B., Bremer E. J. Bacteriol. 1996, 178:5071-5079.
6. Garcia-Estepa R., Canovas D., Iglesias-Guerra F., Ventosa A., Csonka L.N., Nieto J.J., Vargas C. Syst. Appl. Microbiol. 2006, 29:626-633.
7. Sharmila P., Phanindra M.L., Anwar F., Singh K., Gupta S., Pardha Saradhi P. Plant Physiol. Biochem. 2009, 47:391-396.
8. Kathuria H., Giri J., Nataraja K.N., Murata N., Udayakumar M., Tyagi A.K. Plant Biotechnol. J. 2009, 7:512-526.
9. Park E.J., Jeknic Z., Pino M.T., Murata N., Chen T.H. Plant Cell Environ. 2007, 30:994-1005.
10. Park E.J., Jeknic Z., Sakamoto A., DeNoma J., Yuwansiri R., Murata N., Chen T.H. Plant J. 2004, 40:474-487.
11. Mohanty A., Kathuria H., Ferjani A., Sakamoto A., Mohanty P., Murata N., Tyagi A.K. Theor. Appl. Genet. 2002, 106:51-57.
12. Fan F., Gadda G. J. Am. Chem. Soc. 2005, 127:2067-2074.
13. Fan F., Gadda G. J. Am. Chem. Soc. 2005, 127:17954-17961.
14. Quaye O., Gadda G. Arch. Biochem. Biophys. 2009, 489:10-14.
15. Quaye O., Cowins S., Gadda G. J. Biol. Chem. 2009, 284:16990-16997.
16. Quaye O., Lountos G.T., Fan F., Orville A.M., Gadda G. Biochemistry 2008, 47:243-256.
17. Yorita K., Matsuoka T., Misaki H., Massey V. Proc. Natl. Acad. Sci. USA 2000, 97:13039-13044.
18. Yorita K., Misaki H., Palfey B.A., Massey V. Proc. Natl. Acad. Sci. USA 2000, 97:2480-2485.
19. Ghanem M., Fan F., Francis K., Gadda G. Biochemistry 2003, 42:15179-15188.
20. Fan F., Germann M.W., Gadda G. Biochemistry 2006, 45:1979-1986.
21. Fan F., Gadda G. Biochemistry 2007, 46:6402-6408.
22. Mattevi A. Trends Biochem. Sci. 2006, 31:276-283.
23. Ghanem M., Gadda G. Biochemistry 2005, 44:893-904.