Substrate diffusion and oxidation in GMC oxidoreductases: An experimental and computational study on fungal aryl-alcohol oxidase

Biochemical Journal

Volumn 436, Issue 2, 2011, Pages 341-350

  Hernández Ortega, Aitor ^a   Borrelli, Kenneth ^b   Ferreira, Patricia ^c   Medina, Milagros ^c   Martínez, Angel T ^a   Guallar, Victor ^b  

^a CENTRO DE INVESTIGACIONES BIOLÓGICAS   (Spain)

^b BARCELONA SUPERCOMPUTING CENTER   (Spain)

^c UNIVERSITY OF ZARAGOZA   (Spain)

Author keywords

Aryl alcohol oxidase (AAO); Catalytic base; Glucose methanol choline oxidase (GMC) oxidoreductase; Molecular docking; Quantum mechanics molecular mechanics (QM MM); Reaction mechanism

Indexed keywords

ALCOHOL OXIDASE; ARYL ALCOHOL OXIDASE; CHOLINE OXIDASE; HISTIDINE; OXIDOREDUCTASE; UNCLASSIFIED DRUG;

ARTICLE; COMPARATIVE STUDY; DIFFUSION; ENZYME ACTIVE SITE; ENZYME MECHANISM; ENZYME STRUCTURE; ENZYME SUBSTRATE; MATHEMATICAL COMPUTING; MOLECULAR MECHANICS; NUCLEOTIDE SEQUENCE; OXIDATION; PH MEASUREMENT; PRIORITY JOURNAL; PROTON TRANSPORT; QUANTUM MECHANICS; SITE DIRECTED MUTAGENESIS;

ALCOHOL OXIDOREDUCTASES; COMPUTATIONAL BIOLOGY; DIFFUSION; FUNGAL PROTEINS; OXIDATION-REDUCTION; PLEUROTUS; PROTEIN STRUCTURE, SECONDARY; SUBSTRATE SPECIFICITY;

EID: 79956001462     PISSN: 02646021     EISSN: 14708728     Source Type: Journal    
DOI: 10.1042/BJ20102090     Document Type: Article

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