Antagonism of PACAP or microglia function worsens the cardiovascular consequences of kainic-acid-induced seizures in rats

Journal of Neuroscience

Volumn 35, Issue 5, 2015, Pages 2191-2199

  Bhandare, Amol M ^a,b   Mohammed, Suja ^b   Pilowsky, Paul M ^b,c   Farnham, Melissa M J ^a,b  

^a MACQUARIE UNIVERSITY   (Australia)

^b HEART RESEARCH INSTITUTE   (Australia)

^c UNIVERSITY OF SYDNEY   (Australia)

Author keywords

Kainic acid; Microglia; PACAP; Seizure; SUDEP; Sympathetic nerve activity

Indexed keywords

DOXYCYCLINE; HYPOPHYSIS ADENYLATE CYCLASE ACTIVATING POLYPEPTIDE; MINOCYCLINE; OPIATE ANTAGONIST; PACAP 6-38; UNCLASSIFIED DRUG; PEPTIDE FRAGMENT; PITUITARY ADENYLATE-CYCLASE-ACTIVATING-PEPTIDE (6-38);

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; BLOOD PRESSURE; CARDIOVASCULAR FUNCTION; CONTROLLED STUDY; ELECTROENCEPHALOGRAPHY; HEART RATE; MEAN ARTERIAL PRESSURE; MICROGLIA; NERVE CELL STIMULATION; NERVE CONDUCTION; NONHUMAN; PRIORITY JOURNAL; RAT; SEIZURE; SPLANCHNIC NERVE; TACHYCARDIA; TEMPORAL LOBE EPILEPSY; ADRENERGIC SYSTEM; ANIMAL; ARRHYTHMIAS, CARDIAC; COMPLICATION; DRUG EFFECTS; HEART; MALE; METABOLISM; PATHOPHYSIOLOGY; SPINAL CORD; SPRAGUE DAWLEY RAT;

ANIMALS; ARRHYTHMIAS, CARDIAC; BLOOD PRESSURE; DOXYCYCLINE; EPILEPSY, TEMPORAL LOBE; HEART; HEART RATE; MALE; MICROGLIA; MINOCYCLINE; PEPTIDE FRAGMENTS; PITUITARY ADENYLATE CYCLASE-ACTIVATING POLYPEPTIDE; RATS; RATS, SPRAGUE-DAWLEY; SEIZURES; SPINAL CORD; SYMPATHETIC NERVOUS SYSTEM;

EID: 84922389640     PISSN: 02706474     EISSN: 15292401     Source Type: Journal    
DOI: 10.1523/JNEUROSCI.4058-14.2015     Document Type: Article

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