Microglia cells protect neurons by direct engulfment of invading neutrophil granulocytes: A new mechanism of CNS immune privilege

Journal of Neuroscience

Volumn 28, Issue 23, 2008, Pages 5965-5975

  Neumann, Jens ^a,f   Sauerzweig, Steven ^a   Rönicke, Raik ^a   Gunzer, Frank ^b   Dinkel, Klaus ^a   Ullrich, Oliver ^a,c   Gunzer, Matthias ^a,d   Reymann, Klaus G ^a,e,f  

^a OTTO VON GUERICKE UNIVERSITY   (Germany)

^b GERMAN UNIVERSITY IN CAIRO   (Egypt)

^c UNIVERSITY OF ZURICH   (Switzerland)

^d HELMHOLTZ CENTRE FOR INFECTION RESEARCH   (Germany)

^e Institute for Applied Neuroscience Institute für Angewandte Neurowissenschaften FAN Ggmbh   (Germany)

^f LEIBNIZ INSTITUTE FOR NEUROBIOLOGY   (Germany)

Author keywords

Microglia; Neuroinflammation; Phagocytosis; PMN; Polymorphonuclear granulocytes; Stroke; Time lapse imaging

Indexed keywords

ARGINYLGLYCYLASPARTYLSERINE; GLUCOSE; INTEGRIN; LECTIN; N ACETYLGLUCOSAMINE; OXYGEN;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; APOPTOSIS; ARTICLE; BRAIN ISCHEMIA; BRAIN SLICE; CELL CULTURE; CELL INFILTRATION; CELL INVASION; CELL MIGRATION; CELL SURVIVAL; CENTRAL NERVOUS SYSTEM; CONTROLLED STUDY; HUMAN; IN VIVO STUDY; MACROPHAGE; MICROGLIA; NERVE CELL; NERVE INJURY; NEUROPROTECTION; NEUROTOXICITY; NEUTROPHIL; NONHUMAN; NORMAL HUMAN; PHAGOCYTOSIS; PRIORITY JOURNAL; RAT; ANIMAL; CELL MOTION; CELLULAR IMMUNITY; COMPARATIVE STUDY; CYTOLOGY; IMMUNOLOGY; MOUSE; PATHOLOGY; WISTAR RAT;

ANIMALS; CELL MOVEMENT; CELLS, CULTURED; CENTRAL NERVOUS SYSTEM; IMMUNITY, CELLULAR; MICE; MICROGLIA; NEURONS; NEUTROPHILS; PHAGOCYTOSIS; RATS; RATS, WISTAR;

EID: 44949248404     PISSN: 02706474     EISSN: 02706474     Source Type: Journal    
DOI: 10.1523/JNEUROSCI.0060-08.2008     Document Type: Article

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