Interleukin-6 deficiency reduces the brain inflammatory response and increases oxidative stress and neurodegeneration after kainic acid-induced seizures

Neuroscience

Volumn 102, Issue 4, 2001, Pages 805-818

  Penkowa, M ^a   Molinero, A ^b   Carrasco, J ^b   Hidalgo, J ^b  

^a UNIVERSITY OF COPENHAGEN   (Denmark)

^b UNIVERSITAT AUTÒNOMA DE BARCELONA   (Spain)

Author keywords

Apoptosis; Gliosis; Hippocampus; Metallothionein; Neurodegeneration

Indexed keywords

COPPER ZINC SUPEROXIDE DISMUTASE; DEOXYURIDINE TRIPHOSPHATE PYROPHOSPHATASE; DNA NUCLEOTIDYLEXOTRANSFERASE; INTERLEUKIN 1 BETA CONVERTING ENZYME; INTERLEUKIN 1BETA; INTERLEUKIN 6; KAINIC ACID; MANGANESE SUPEROXIDE DISMUTASE; METALLOTHIONEIN; NITRIC OXIDE SYNTHASE; PEROXYNITRITE; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL TISSUE; APOPTOSIS; ARTICLE; ASTROCYTOSIS; BLOOD BRAIN BARRIER; CELL DEATH; CONTROLLED STUDY; ENCEPHALITIS; GLIOSIS; HIPPOCAMPUS; HISTOPATHOLOGY; IMMUNOREACTIVITY; INFLAMMATION; LIPID PEROXIDATION; MACROPHAGE ACTIVATION; MORTALITY; MOUSE; NERVE CELL; NERVE DEGENERATION; NITRATION; NONHUMAN; OXIDATIVE STRESS; PRIORITY JOURNAL; PROTEIN EXPRESSION; SEIZURE;

ANIMALS; APOPTOSIS; BLOOD-BRAIN BARRIER; ENCEPHALITIS; EPILEPSY; EXCITATORY AMINO ACID AGONISTS; GENE EXPRESSION; GLIOSIS; HIPPOCAMPUS; IN SITU NICK-END LABELING; INTERLEUKIN-6; KAINIC ACID; MACROPHAGES; METALLOTHIONEIN; MICE; MICE, KNOCKOUT; MICROGLIA; NERVE DEGENERATION; OXIDATIVE STRESS; SEIZURES; SUPEROXIDE DISMUTASE;

EID: 0035857468     PISSN: 03064522     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0306-4522(00)00515-7     Document Type: Article

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