Induction of colon cancer cell death by 7-hydroxystaurosporine (UCN-01) is associated with increased p38 MAPK and decreased Bcl-xL

Anti-Cancer Drugs

Volumn 14, Issue 9, 2003, Pages 761-766

  Chan, Ursula P F ^a   Lee, Janet F Y ^a   Wang, S H ^b   Leung, Ka L ^a   Chen, George G ^a  

^a CHINESE UNIVERSITY OF HONG KONG   (Hong Kong)

^b UNIVERSITY OF MICHIGAN MEDICAL SCHOOL   (United States)

Author keywords

Bcl xL; Cell death; Colon cancer; p38 MAPK; UCN 01

Indexed keywords

7 HYDROXYSTAUROSPORINE; CASPASE 3; DNA FRAGMENT; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; MITOGEN ACTIVATED PROTEIN KINASE; MITOGEN ACTIVATED PROTEIN KINASE P38; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR GAMMA; PROTEIN BCL XL; UNCLASSIFIED DRUG;

ANTINEOPLASTIC ACTIVITY; APOPTOSIS; ARTICLE; CANCER CELL CULTURE; CANCER INHIBITION; CELL DEATH; COLON CANCER; CONTROLLED STUDY; CYTOTOXICITY; DOSE TIME EFFECT RELATION; DRUG MECHANISM; ENZYME IMMUNOASSAY; GENE OVEREXPRESSION; HUMAN; HUMAN CELL; PRIORITY JOURNAL; WESTERN BLOTTING;

EID: 0242351216     PISSN: 09594973     EISSN: None     Source Type: Journal    
DOI: 10.1097/00001813-200310000-00012     Document Type: Article

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