메뉴 건너뛰기




Volumn 300, Issue 1, 2011, Pages

Intrathecal PACAP-38 causes increases in sympathetic nerve activity and heart rate but not blood pressure in the spontaneously hypertensive rat

Author keywords

Pituitary adenylate cyclase activating polypeptide; Spinal cord; Sympathetic activity

Indexed keywords

BLOCKING AGENT; HYPOPHYSIS ADENYLATE CYCLASE ACTIVATING POLYPEPTIDE; HYPOPHYSIS ADENYLATE CYCLASE ACTIVATING POLYPEPTIDE 6 38; MESSENGER RNA; UNCLASSIFIED DRUG;

EID: 78651337689     PISSN: 03636135     EISSN: 15221539     Source Type: Journal    
DOI: 10.1152/ajpheart.00662.2010     Document Type: Article
Times cited : (23)

References (51)
  • 1
    • 0034307597 scopus 로고    scopus 로고
    • Mechanisms mediating pituitary adenylate cyclase-activating polypeptide depolarization of rat sympathetic neurons
    • Beaudet MM, Parsons RL, Braas KM, May V. Mechanisms mediating pituitary adenylate cyclase-activating polypeptide depolarization of rat sympathetic neurons. J Neurosci 20: 7353-7361, 2000.
    • (2000) J Neurosci , vol.20 , pp. 7353-7361
    • Beaudet, M.M.1    Parsons, R.L.2    Braas, K.M.3    May, V.4
  • 2
    • 0021997983 scopus 로고
    • Electrophysiological study of cardiovascular neurons in the rostral ventrolateral medulla in rats
    • Brown DL, Guyenet PG. Electrophysiological study of cardiovascular neurons in the rostral ventrolateral medulla in rats. Circ Res 56: 359-369, 1985.
    • (1985) Circ Res , vol.56 , pp. 359-369
    • Brown, D.L.1    Guyenet, P.G.2
  • 3
    • 0025252980 scopus 로고
    • Presence of highly selective receptors for PACAP (pituitary adenylate cyclase activating peptide) in membranes from the rat pancreatic acinar cell line AR 4-2J
    • Buscail L, Gourlet P, Cauvin A, De Neef P, Gossen D, Arimura A, Miyata A, Coy DH, Robberecht P, Christophe J. Presence of highly selective receptors for PACAP (pituitary adenylate cyclase activating peptide) in membranes from the rat pancreatic acinar cell line AR 4-2J. FEBS Lett 262: 77-81, 1990.
    • (1990) FEBS Lett , vol.262 , pp. 77-81
    • Buscail, L.1    Gourlet, P.2    Cauvin, A.3    De Neef, P.4    Gossen, D.5    Arimura, A.6    Miyata, A.7    Coy, D.H.8    Robberecht, P.9    Christophe, J.10
  • 5
    • 0025899048 scopus 로고
    • Properties and distribution of receptors for pituitary adenylate cyclase activating peptide (PACAP) in rat brain and spinal cord
    • Cauvin A, Robberecht P, De Neef P, Gourlet P, Vandermeers A, Vandermeers-Piret MC, Christophe J. Properties and distribution of receptors for pituitary adenylate cyclase activating peptide (PACAP) in rat brain and spinal cord. Regul Pept 35: 161-173, 1991.
    • (1991) Regul Pept , vol.35 , pp. 161-173
    • Cauvin, A.1    Robberecht, P.2    De Neef, P.3    Gourlet, P.4    Vandermeers, A.5    Vandermeers-Piret, M.C.6    Christophe, J.7
  • 6
    • 33846034012 scopus 로고    scopus 로고
    • Hypothalamic and brainstem sources of pituitary adenylate cyclase-activating polypeptide nerve fibers innervating the hypothalamic paraventricular nucleus in the rat
    • Das M, Vihlen CS, Legradi G. Hypothalamic and brainstem sources of pituitary adenylate cyclase-activating polypeptide nerve fibers innervating the hypothalamic paraventricular nucleus in the rat. J Comp Neurol 500: 761-776, 2007.
    • (2007) J Comp Neurol , vol.500 , pp. 761-776
    • Das, M.1    Vihlen, C.S.2    Legradi, G.3
  • 7
    • 0030987218 scopus 로고    scopus 로고
    • Evidence for roles of vasoactive intestinal polypeptide (VIP) and pituitary adenylate cyclase activating polypeptide (PACAP) receptors in modulating the responses of rat dorsal horn neurons to sensory inputs
    • Dickinson T, Fleetwood-Walker SM, Mitchell R, Lutz EM. Evidence for roles of vasoactive intestinal polypeptide (VIP) and pituitary adenylate cyclase activating polypeptide (PACAP) receptors in modulating the responses of rat dorsal horn neurons to sensory inputs. Neuropeptides 31: 175-185, 1997.
    • (1997) Neuropeptides , vol.31 , pp. 175-185
    • Dickinson, T.1    Fleetwood-Walker, S.M.2    Mitchell, R.3    Lutz, E.M.4
  • 8
    • 60849086453 scopus 로고    scopus 로고
    • VPAC and PAC receptors: From ligands to function
    • Dickson L, Finlayson K. VPAC and PAC receptors: from ligands to function. Pharmacol Ther 121: 294-316, 2009.
    • (2009) Pharmacol Ther , vol.121 , pp. 294-316
    • Dickson, L.1    Finlayson, K.2
  • 9
    • 37649023416 scopus 로고    scopus 로고
    • Presence of pituitary adenylate cyclase-activating polypeptide (PACAP) defines a subpopulation of hypothalamic POMC neurons
    • Durr K, Norsted E, Gomuc B, Suarez E, Hannibal J, Meister B. Presence of pituitary adenylate cyclase-activating polypeptide (PACAP) defines a subpopulation of hypothalamic POMC neurons. Brain Res 1186: 203-211, 2007.
    • (2007) Brain Res , vol.1186 , pp. 203-211
    • Durr, K.1    Norsted, E.2    Gomuc, B.3    Suarez, E.4    Hannibal, J.5    Meister, B.6
  • 10
    • 41749094947 scopus 로고    scopus 로고
    • PACAP is expressed in sympathoexcitatory bulbospinal C1 neurons of the brain stem and increases sympathetic nerve activity in vivo
    • Farnham MMJ, Li Q, Goodchild AK, Pilowsky PM. PACAP is expressed in sympathoexcitatory bulbospinal C1 neurons of the brain stem and increases sympathetic nerve activity in vivo. Am J Physiol Regul Integr Comp Physiol 294: R1304-R1311, 2008.
    • (2008) Am J Physiol Regul Integr Comp Physiol , vol.294
    • Farnham, M.M.J.1    Li, Q.2    Goodchild, A.K.3    Pilowsky, P.M.4
  • 11
    • 0842301570 scopus 로고    scopus 로고
    • Evidence for the involvement of VPAC1 and VPAC2 receptors in pressure-induced vasodilatation in rodents
    • Fizanne L, Sigaudo-Roussel D, Saumet JL, Fromy B. Evidence for the involvement of VPAC1 and VPAC2 receptors in pressure-induced vasodilatation in rodents. J Physiol 554: 519-528, 2004.
    • (2004) J Physiol , vol.554 , pp. 519-528
    • Fizanne, L.1    Sigaudo-Roussel, D.2    Saumet, J.L.3    Fromy, B.4
  • 13
    • 0036773485 scopus 로고    scopus 로고
    • Temperature-sensitive phenotype in mice lacking pituitary adenylate cyclase-activating polypeptide
    • Gray SL, Yamaguchi N, Vencova P, Sherwood NM. Temperature-sensitive phenotype in mice lacking pituitary adenylate cyclase-activating polypeptide. Endocrinology 143: 3946-3954, 2002.
    • (2002) Endocrinology , vol.143 , pp. 3946-3954
    • Gray, S.L.1    Yamaguchi, N.2    Vencova, P.3    Sherwood, N.M.4
  • 14
    • 33746883552 scopus 로고    scopus 로고
    • Long-term administration of PACAP receptor antagonist, PACAP(6-27), impairs glucose tolerance and insulin sensitivity in obese diabetic ob/ob mice
    • Green BD, Irwin N, Cassidy RS, Gault VA, Flatt PR. Long-term administration of PACAP receptor antagonist, PACAP(6-27), impairs glucose tolerance and insulin sensitivity in obese diabetic ob/ob mice. Peptides 27: 2343-2349, 2006.
    • (2006) Peptides , vol.27 , pp. 2343-2349
    • Green, B.D.1    Irwin, N.2    Cassidy, R.S.3    Gault, V.A.4    Flatt, P.R.5
  • 15
    • 33745712914 scopus 로고    scopus 로고
    • The sympathetic control of blood pressure
    • Guyenet PG. The sympathetic control of blood pressure. Nat Rev Neurosci 7: 335-346, 2006.
    • (2006) Nat Rev Neurosci , vol.7 , pp. 335-346
    • Guyenet, P.G.1
  • 16
    • 0037039471 scopus 로고    scopus 로고
    • Pituitary adenylate cyclase-activating polypeptide is a sympathoadrenal neurotransmitter involved in catecholamine regulation and glucohomeostasis
    • Hamelink C, Tjurmina O, Damadzic R, Young WS, Weihe E, Lee HW, Eiden LE. Pituitary adenylate cyclase-activating polypeptide is a sympathoadrenal neurotransmitter involved in catecholamine regulation and glucohomeostasis. Proc Natl Acad Sci USA 99: 461-466, 2002.
    • (2002) Proc Natl Acad Sci USA , vol.99 , pp. 461-466
    • Hamelink, C.1    Tjurmina, O.2    Damadzic, R.3    Young, W.S.4    Weihe, E.5    Lee, H.W.6    Eiden, L.E.7
  • 17
    • 0037175342 scopus 로고    scopus 로고
    • Pituitary adenylate cyclase-activating peptide in the rat central nervous system: An immunohistochemical and in situ hybridization study
    • Hannibal J. Pituitary adenylate cyclase-activating peptide in the rat central nervous system: an immunohistochemical and in situ hybridization study. J Comp Neurol 453: 389-417, 2002.
    • (2002) J Comp Neurol , vol.453 , pp. 389-417
    • Hannibal, J.1
  • 18
    • 0030962604 scopus 로고    scopus 로고
    • Pituitary adenylate cyclase-activating peptide (PACAP) in the retinohypothalamic tract: A potential daytime regulator of the biological clock
    • Hannibal J, Ding JM, Chen D, Fahrenkrug J, Larsen PJ, Gillette MU, Mikkelsen JD. Pituitary adenylate cyclase-activating peptide (PACAP) in the retinohypothalamic tract: a potential daytime regulator of the biological clock. J Neurosci 17: 2637-2644, 1997.
    • (1997) J Neurosci , vol.17 , pp. 2637-2644
    • Hannibal, J.1    Ding, J.M.2    Chen, D.3    Fahrenkrug, J.4    Larsen, P.J.5    Gillette, M.U.6    Mikkelsen, J.D.7
  • 19
    • 0028888345 scopus 로고
    • Gene expression of pituitary adenylate cyclase activating polypeptide (PACAP) in the rat hypothalamus
    • Abstract
    • Hannibal J, Mikkelsen JD, Clausen H, Holst JJ, Wulff BS, Fahrenkrug J. Gene expression of pituitary adenylate cyclase activating polypeptide (PACAP) in the rat hypothalamus (Abstract). Regul Pept 55: 133, 1995.
    • (1995) Regul Pept , vol.55 , pp. 133
    • Hannibal, J.1    Mikkelsen, J.D.2    Clausen, H.3    Holst, J.J.4    Wulff, B.S.5    Fahrenkrug, J.6
  • 22
    • 0033954453 scopus 로고    scopus 로고
    • Excitatory amino acids in the rostral ventrolateral medulla support blood pressure in spontaneously hypertensive rats
    • Ito S, Komatsu K, Tsukamoto K, Sved AF. Excitatory amino acids in the rostral ventrolateral medulla support blood pressure in spontaneously hypertensive rats. Hypertension 35: 413-417, 2000.
    • (2000) Hypertension , vol.35 , pp. 413-417
    • Ito, S.1    Komatsu, K.2    Tsukamoto, K.3    Sved, A.F.4
  • 23
    • 78651143323 scopus 로고
    • Neurogenic hypertension in the rat
    • Krieger EM. Neurogenic hypertension in the rat. Circ Res 15: 511-521, 1964.
    • (1964) Circ Res , vol.15 , pp. 511-521
    • Krieger, E.M.1
  • 24
    • 67651171664 scopus 로고    scopus 로고
    • PACAP regulates immediate catecholamine release from adrenal chromaffin cells in an activity-dependent manner through a protein kinase C-dependent pathway
    • Kuri BA, Chan SA, Smith CB. PACAP regulates immediate catecholamine release from adrenal chromaffin cells in an activity-dependent manner through a protein kinase C-dependent pathway. J Neurochem 110: 1214-1225, 2009.
    • (2009) J Neurochem , vol.110 , pp. 1214-1225
    • Kuri, B.A.1    Chan, S.A.2    Smith, C.B.3
  • 25
    • 3543077645 scopus 로고    scopus 로고
    • Distribution of vasoactive intestinal peptide and pituitary adenylate cyclase-activating polypeptide receptors (VPAC1, VPAC2, and PAC1 receptor) in the rat brain
    • Kyeung MJ, Yoon HC, Min KK, Ryoung HN, Byung LL, Kyung HL, Choong IC. Distribution of vasoactive intestinal peptide and pituitary adenylate cyclase-activating polypeptide receptors (VPAC1, VPAC2, and PAC1 receptor) in the rat brain. J Comp Neurol 476: 388-413, 2004.
    • (2004) J Comp Neurol , vol.476 , pp. 388-413
    • Kyeung, M.J.1    Yoon, H.C.2    Min, K.K.3    Ryoung, H.N.4    Byung, L.L.5    Kyung, H.L.6    Choong, I.C.7
  • 26
    • 0031057743 scopus 로고    scopus 로고
    • Excitatory action of pituitary adenylate cyclase activating polypeptide on rat sympathetic preganglionic neurons in vivo and in vitro (Abstract)
    • Lai CC, Wu SY, Lin HH, Dun NJ. Excitatory action of pituitary adenylate cyclase activating polypeptide on rat sympathetic preganglionic neurons in vivo and in vitro (Abstract). Brain Res 748: 189, 1997.
    • (1997) Brain Res , vol.748 , pp. 189
    • Lai, C.C.1    Wu, S.Y.2    Lin, H.H.3    Dun, N.J.4
  • 27
    • 26944476661 scopus 로고    scopus 로고
    • Pre-protachykinin a mRNA is colocalized with tyrosine hydroxylase-immunoreactivity in bulbospinal neurons
    • Li Q, Goodchild AK, Seyedabadi M, Pilowsky PM. Pre-protachykinin A mRNA is colocalized with tyrosine hydroxylase-immunoreactivity in bulbospinal neurons. Neuroscience 136: 205-216, 2005.
    • (2005) Neuroscience , vol.136 , pp. 205-216
    • Li, Q.1    Goodchild, A.K.2    Seyedabadi, M.3    Pilowsky, P.M.4
  • 28
    • 0030047717 scopus 로고    scopus 로고
    • Properties of presympathetic neurones in the rostral ventrolateral medulla in the rat: An intracellular study in vivo
    • Lipski J, Kanjhan R, Kruszewska B, Rong W. Properties of presympathetic neurones in the rostral ventrolateral medulla in the rat: an intracellular study in vivo. J Physiol 490: 729-744, 1996.
    • (1996) J Physiol , vol.490 , pp. 729-744
    • Lipski, J.1    Kanjhan, R.2    Kruszewska, B.3    Rong, W.4
  • 29
    • 0028832479 scopus 로고
    • Barosensitive neurons in the rostral ventrolateral medulla of the rat in vivo: Morphological properties and relationship to C1 adrenergic neurons
    • Lipski J, Kanjhan R, Kruszewska B, Smith M. Barosensitive neurons in the rostral ventrolateral medulla of the rat in vivo: morphological properties and relationship to C1 adrenergic neurons. Neuroscience 69: 601-618, 1995.
    • (1995) Neuroscience , vol.69 , pp. 601-618
    • Lipski, J.1    Kanjhan, R.2    Kruszewska, B.3    Smith, M.4
  • 31
    • 0030007395 scopus 로고    scopus 로고
    • Altered c-fos in rostral medulla and spinal cord of spontaneously hypertensive rats
    • Minson J, Arnolda L, Llewellyn-Smith I, Pilowsky P, Chalmers J. Altered c-fos in rostral medulla and spinal cord of spontaneously hypertensive rats. Hypertension 27: 433-441, 1996.
    • (1996) Hypertension , vol.27 , pp. 433-441
    • Minson, J.1    Arnolda, L.2    Llewellyn-Smith, I.3    Pilowsky, P.4    Chalmers, J.5
  • 33
    • 0025075727 scopus 로고
    • Isolation of a neuropeptide corresponding to the N-terminal 27 residues of the pituitary adenylate cyclase activating polypeptide with 38 residues (PACAP38)
    • Miyata A, Jiang L, Dahl RD, Kitada C, Kubo K, Fujino M, Minamino N, Arimura A. Isolation of a neuropeptide corresponding to the N-terminal 27 residues of the pituitary adenylate cyclase activating polypeptide with 38 residues (PACAP38). Biochem Biophys Res Commun 170: 643-648, 1990.
    • (1990) Biochem Biophys Res Commun , vol.170 , pp. 643-648
    • Miyata, A.1    Jiang, L.2    Dahl, R.D.3    Kitada, C.4    Kubo, K.5    Fujino, M.6    Minamino, N.7    Arimura, A.8
  • 34
    • 0037040522 scopus 로고    scopus 로고
    • Lateralisation of projections from the rostral ventrolateral medulla to sympathetic preganglionic neurons in the rat
    • Moon EA, Goodchild AK, Pilowsky PM. Lateralisation of projections from the rostral ventrolateral medulla to sympathetic preganglionic neurons in the rat. Brain Res 929: 181-190, 2002.
    • (2002) Brain Res , vol.929 , pp. 181-190
    • Moon, E.A.1    Goodchild, A.K.2    Pilowsky, P.M.3
  • 35
    • 0027327371 scopus 로고
    • Pituitary adenylate cyclase-activating polypeptide stimulates arginine vasopressin release in conscious rats
    • Murase T, Kondo K, Otake K, Oiso Y. Pituitary adenylate cyclase-activating polypeptide stimulates arginine vasopressin release in conscious rats. Neuroendocrinology 57: 1092-1096, 1993.
    • (1993) Neuroendocrinology , vol.57 , pp. 1092-1096
    • Murase, T.1    Kondo, K.2    Otake, K.3    Oiso, Y.4
  • 36
    • 34248389384 scopus 로고    scopus 로고
    • PACAP in the glucose and energy homeostasis: Physiological role and therapeutic potential
    • Nakata M, Yada T. PACAP in the glucose and energy homeostasis: physiological role and therapeutic potential. Curr Pharm Des 13: 1105-1112, 2007.
    • (2007) Curr Pharm Des , vol.13 , pp. 1105-1112
    • Nakata, M.1    Yada, T.2
  • 37
    • 0011910306 scopus 로고
    • Development of a strain of spontaneously hypertensive rats
    • Okamoto K, Aoki K. Development of a strain of spontaneously hypertensive rats. Jpn Circ J 27: 282-293, 1963.
    • (1963) Jpn Circ J , vol.27 , pp. 282-293
    • Okamoto, K.1    Aoki, K.2
  • 38
    • 55449116430 scopus 로고    scopus 로고
    • Monosynaptic excitatory connection from the rostral ventrolateral medulla to sympathetic preganglionic neurons revealed by simultaneous recordings
    • Oshima N, Kumagai H, Onimaru H, Kawai A, Pilowsky PM, Iigaya K, Takimoto C, Hayashi K, Saruta T, Itoh H. Monosynaptic excitatory connection from the rostral ventrolateral medulla to sympathetic preganglionic neurons revealed by simultaneous recordings. Hypertens Res 31: 1445-1454, 2008.
    • (2008) Hypertens Res , vol.31 , pp. 1445-1454
    • Oshima, N.1    Kumagai, H.2    Onimaru, H.3    Kawai, A.4    Pilowsky, P.M.5    Iigaya, K.6    Takimoto, C.7    Hayashi, K.8    Saruta, T.9    Itoh, H.10
  • 39
    • 0031418069 scopus 로고    scopus 로고
    • Central administration of PACAP stimulates gastric secretion mediated through the vagal pathway in anesthetized rats
    • Ozawa M, Aono M, Mizuta K, Moriga M, Okuma M. Central administration of PACAP stimulates gastric secretion mediated through the vagal pathway in anesthetized rats. Dig Dis Sci 42: 2552-2559, 1997.
    • (1997) Dig Dis Sci , vol.42 , pp. 2552-2559
    • Ozawa, M.1    Aono, M.2    Mizuta, K.3    Moriga, M.4    Okuma, M.5
  • 40
    • 33846820107 scopus 로고    scopus 로고
    • Central command regulation of circulatory function mediated by descending pontine cholinergic inputs to sympathoexcitatory rostral ventrolateral medulla neurons
    • Padley JR, Kumar NN, Li Q, Nguyen TB, Pilowsky PM, Goodchild AK. Central command regulation of circulatory function mediated by descending pontine cholinergic inputs to sympathoexcitatory rostral ventrolateral medulla neurons. Circ Res 100: 284-291, 2007.
    • (2007) Circ Res , vol.100 , pp. 284-291
    • Padley, J.R.1    Kumar, N.N.2    Li, Q.3    Nguyen, T.B.4    Pilowsky, P.M.5    Goodchild, A.K.6
  • 43
    • 0036734231 scopus 로고    scopus 로고
    • Baroreceptor reflex pathways and neurotransmitters: 10 Years on
    • Pilowsky PM, Goodchild AK. Baroreceptor reflex pathways and neurotransmitters: 10 years on. J Hypertens 20: 1675-1688, 2002.
    • (2002) J Hypertens , vol.20 , pp. 1675-1688
    • Pilowsky, P.M.1    Goodchild, A.K.2
  • 44
    • 0027935601 scopus 로고
    • Intracellular recording from sympathetic preganglionic neurons in cat lumbar spinal cord
    • Pilowsky PM, Llewellyn-Smith IJ, Arnolda L, Minson J, Chalmers J. Intracellular recording from sympathetic preganglionic neurons in cat lumbar spinal cord. Brain Res 656: 319-328, 1994.
    • (1994) Brain Res , vol.656 , pp. 319-328
    • Pilowsky, P.M.1    Llewellyn-Smith, I.J.2    Arnolda, L.3    Minson, J.4    Chalmers, J.5
  • 45
    • 0026664403 scopus 로고
    • Structural requirements for the occupancy of pituitary adenylate-cyclase-activating-peptide (PACAP) receptors and adenylate cyclase activation in human neuroblastoma NB-OK-1 cell membranes. Discovery of PACAP(6-38) as a potent antagonist
    • Robberecht P, Gourlet P, De Neef P, Woussen-Colle MC, Vandermeers-Piret MC, Vandermeers A, Christophe J. Structural requirements for the occupancy of pituitary adenylate-cyclase-activating-peptide (PACAP) receptors and adenylate cyclase activation in human neuroblastoma NB-OK-1 cell membranes. Discovery of PACAP(6-38) as a potent antagonist. Eur J Biochem 207: 239-246, 1992.
    • (1992) Eur J Biochem , vol.207 , pp. 239-246
    • Robberecht, P.1    Gourlet, P.2    De Neef, P.3    Woussen-Colle, M.C.4    Vandermeers-Piret, M.C.5    Vandermeers, A.6    Christophe, J.7
  • 48
    • 0033611308 scopus 로고    scopus 로고
    • Location and electrophysiological characterization of rostral medullary adrenergic neurons that contain neuropeptide Y mRNA in rat medulla
    • Stornetta RL, Akey PJ, Guyenet PG. Location and electrophysiological characterization of rostral medullary adrenergic neurons that contain neuropeptide Y mRNA in rat medulla. J Comp Neurol 415: 482-500, 1999.
    • (1999) J Comp Neurol , vol.415 , pp. 482-500
    • Stornetta, R.L.1    Akey, P.J.2    Guyenet, P.G.3
  • 49
    • 0037066060 scopus 로고    scopus 로고
    • Vesicular glutamate transporter DNPI/VGLUT2 mRNA is present in C1 and several other groups of brainstem catecholaminergic neurons
    • Stornetta RL, Sevigny CP, Guyenet PG. Vesicular glutamate transporter DNPI/VGLUT2 mRNA is present in C1 and several other groups of brainstem catecholaminergic neurons. J Comp Neurol 444: 191-206, 2002.
    • (2002) J Comp Neurol , vol.444 , pp. 191-206
    • Stornetta, R.L.1    Sevigny, C.P.2    Guyenet, P.G.3
  • 51
    • 0034048147 scopus 로고    scopus 로고
    • Pituitary adenylate cyclase-activating polypeptide and its receptors: From structure to functions
    • Vaudry D, Gonzalez BJ, Basille M, Yon L, Fournier A, Vaudry H. Pituitary adenylate cyclase-activating polypeptide and its receptors: from structure to functions. Pharmacol Rev 52: 269-324, 2000.
    • (2000) Pharmacol Rev , vol.52 , pp. 269-324
    • Vaudry, D.1    Gonzalez, B.J.2    Basille, M.3    Yon, L.4    Fournier, A.5    Vaudry, H.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.