메뉴 건너뛰기




Volumn 17, Issue 12, 2014, Pages 929-938

Black cumin (Nigella sativa) and its constituent (thymoquinone): A review on antimicrobial effects

Author keywords

Antibacterial; Antifungal; Antimicrobial; Antiparasite; Antischistosoma; Antivirus; Nigella sativa; Thymoquinone

Indexed keywords

ALKALOID; ESSENTIAL OIL; MELANIN; THYMOQUINONE; UNSATURATED FATTY ACID;

EID: 84922389279     PISSN: 20083866     EISSN: 20083874     Source Type: Journal    
DOI: None     Document Type: Review
Times cited : (257)

References (71)
  • 2
    • 0033059343 scopus 로고    scopus 로고
    • Chemical composition and medicinal properties of Nigella sativa Linn
    • Khan MR. Chemical composition and medicinal properties of Nigella sativa Linn. Inflammo pharmacology 1999; 7:13-35.
    • (1999) Inflammo Pharmacology , vol.7 , pp. 13-35
    • Khan, M.R.1
  • 3
    • 84922348436 scopus 로고    scopus 로고
    • A review on therapeutic potential of Nigella sativa (Kalonji) seeds
    • Tembhurne SV, Feroz S, Sakarkar DM. A review on therapeutic potential of Nigella sativa (kalonji) seeds. J Med Plants Res 2014; 8:166-167.
    • (2014) J Med Plants Res , vol.8 , pp. 166-167
    • Tembhurne, S.V.1    Feroz, S.2    Sakarkar, D.M.3
  • 5
    • 0001086062 scopus 로고
    • The sterols of Nigella sativa seed oil
    • Staphylakis PK, Gegiou D. The sterols of Nigella sativa seed oil. Phytochemistry 1986; 25:761-763.
    • (1986) Phytochemistry , vol.25 , pp. 761-763
    • Staphylakis, P.K.1    Gegiou, D.2
  • 7
    • 0033012875 scopus 로고    scopus 로고
    • Immunomodulatory effect of Nigella sativa proteins fractionated by ion exchange chromatography
    • Haq A, Lobo I, Al-Tufail M, Rama NR, Sedairy ST. Immunomodulatory effect of Nigella sativa proteins fractionated by ion exchange chromatography. Int J Immunopharmacol 1999; 21:283-285.
    • (1999) Int J Immunopharmacol , vol.21 , pp. 283-285
    • Haq, A.1    Lobo, I.2    Al-Tufail, M.3    Rama, N.R.4    Sedairy, S.T.5
  • 8
    • 23644444586 scopus 로고    scopus 로고
    • Study on the anticonvulsant activity of thymoquinone, the major constituent of Nigella sativa L. Seeds, through intracerebroventricular injection
    • Parvardeh S, Nassiri-Asl M, Mansouri MT, Hosseinzadeh H. Study on the anticonvulsant activity of thymoquinone, the major constituent of Nigella sativa L. seeds, through intracerebroventricular injection. J Med Plants 2005; 4:45-52.
    • (2005) J Med Plants , vol.4 , pp. 45-52
    • Parvardeh, S.1    Nassiri-Asl, M.2    Mansouri, M.T.3    Hosseinzadeh, H.4
  • 9
    • 1042303460 scopus 로고    scopus 로고
    • Anticonvulsant effects of thymoquinone, the major constituent of Nigella sativa seeds, in mice
    • Hosseinzadeh H, Parvardeh S. Anticonvulsant effects of thymoquinone, the major constituent of Nigella sativa seeds, in mice. Phytomedicine 2004; 11:56-64.
    • (2004) Phytomedicine , vol.11 , pp. 56-64
    • Hosseinzadeh, H.1    Parvardeh, S.2
  • 10
    • 17444422880 scopus 로고    scopus 로고
    • Intracerebroventricular administration of thymoquinone, the major constituent of Nigella sativa seeds, suppresses epileptic seizures in rats
    • Hosseinzadeh H, Parvardeh S, Nassiri-Asl M, Mansouri MT. Intracerebroventricular administration of thymoquinone, the major constituent of Nigella sativa seeds, suppresses epileptic seizures in rats. Med Sci Monit 2005; 11:BR106-BR110.
    • (2005) Med Sci Monit , vol.11 , pp. BR106-BR110
    • Hosseinzadeh, H.1    Parvardeh, S.2    Nassiri-Asl, M.3    Mansouri, M.T.4
  • 11
    • 84862863403 scopus 로고    scopus 로고
    • Effect of thymoquinone, a constituent of Nigella sativa L., on ischemia-reperfusion in rat skeletal muscle
    • Hosseinzadeh H, Taiari S, Nassiri-Asl M. Effect of thymoquinone, a constituent of Nigella sativa L., on ischemia-reperfusion in rat skeletal muscle. N-S Arch Pharmacol 2012; 385:503-508.
    • (2012) N-S Arch Pharmacol , vol.385 , pp. 503-508
    • Hosseinzadeh, H.1    Taiari, S.2    Nassiri-Asl, M.3
  • 13
    • 41149137253 scopus 로고    scopus 로고
    • Thymoquinone reduces mouse colon tumor cell invasion and inhibits tumor growth in murine colon cancer models
    • Gali-Muhtasib H, Ocker M, Kuester D, Krueger S, El-Hajj Z, Diestel A, et al. Thymoquinone reduces mouse colon tumor cell invasion and inhibits tumor growth in murine colon cancer models. J Cell Mol Med 2008; 12:330-342.
    • (2008) J Cell Mol Med , vol.12 , pp. 330-342
    • Gali-Muhtasib, H.1    Ocker, M.2    Kuester, D.3    Krueger, S.4    El-Hajj, Z.5    Diestel, A.6
  • 14
    • 79955977776 scopus 로고    scopus 로고
    • Antibacterial activity of thymoquinone and thymohydroquinone of Nigella sativa L. And their interaction with some antibiotics
    • Halawani E. Antibacterial activity of thymoquinone and thymohydroquinone of Nigella sativa L. and their interaction with some antibiotics. Adv Biol Res 2009; 3:148-152.
    • (2009) Adv Biol Res , vol.3 , pp. 148-152
    • Halawani, E.1
  • 15
    • 84922362924 scopus 로고    scopus 로고
    • Efficacy of thymoquinone against vaginal candidiasis in prednisolone-induced immunosuppressed mice
    • Abdel Azeiz AZ, Saad AH, Darweesh MF. Efficacy of thymoquinone against vaginal candidiasis in prednisolone-induced immunosuppressed mice. J Am Sci 2013; 9:155-159.
    • (2013) J am Sci , vol.9 , pp. 155-159
    • Abdel Azeiz, A.Z.1    Saad, A.H.2    Darweesh, M.F.3
  • 16
    • 0001209913 scopus 로고
    • Medicinal plants
    • Phillips JD. Medicinal plants. Biologist 1992; 39, 187-191.
    • (1992) Biologist , vol.39 , pp. 187-191
    • Phillips, J.D.1
  • 17
    • 0018870971 scopus 로고
    • Traditional medicine in health care
    • Sayed MD. Traditional medicine in health care, J. Ethnopharmacol 1980; 2:19-22.
    • (1980) J. Ethnopharmacol , vol.2 , pp. 19-22
    • Sayed, M.D.1
  • 18
    • 0033837710 scopus 로고    scopus 로고
    • Antioxidant activity of Nigella sativa essential oil
    • Burits M, Bucar F. Antioxidant activity of Nigella sativa essential oil. Phytother Res 2000; 14:323-328.
    • (2000) Phytother Res , vol.14 , pp. 323-328
    • Burits, M.1    Bucar, F.2
  • 19
    • 84893025828 scopus 로고    scopus 로고
    • Pharmacognosy and pharmacology of Nigella sativa
    • Rajsekhar S, Kuldeep B. Pharmacognosy and pharmacology of Nigella sativa. J Pharm Res 2011; 2:36-39.
    • (2011) J Pharm Res , vol.2 , pp. 36-39
    • Rajsekhar, S.1    Kuldeep, B.2
  • 23
    • 84922370635 scopus 로고
    • Ministry of Health and Family Welfare
    • The Ayurvedic Pharmacopoeia of India, part 1
    • The Ayurvedic Pharmacopoeia of India, part 1, Ministry of Health and Family Welfare. New Delhi. 1989; 119-120.
    • (1989) New Delhi , pp. 119-120
  • 24
    • 34548587212 scopus 로고    scopus 로고
    • Effect of Nigella sativa seed extracts on ischemia-reperfusion in rat skeletal muscle
    • Hosseinzadeh H, Moghim FF, Mansouri SMT. Effect of Nigella sativa seed extracts on ischemia-reperfusion in rat skeletal muscle. Pharmacologyonline 2007; 2:326335.
    • (2007) Pharmacologyonline , pp. 2
    • Hosseinzadeh, H.1    Moghim, F.F.2    Mansouri, S.3
  • 25
    • 53249097538 scopus 로고    scopus 로고
    • Antitussive effect of thymoquinone a constituent of
    • Hosseinzadeh H, Eskandari M, Ziaee T. Antitussive effect of thymoquinone a constituent ofNigella Sativa Seeds in guinea pigs. Pharmacology online 2008; 2:480-484.
    • (2008) Pharmacology Online , vol.2 , pp. 480-484
    • Hosseinzadeh, H.1    Eskandari, M.2    Ziaee, T.3
  • 28
    • 0041306217 scopus 로고    scopus 로고
    • Anti-ulcer effect of Nigella sativa Linn against gastric ulcers in rats
    • Rajkapoor B, Anandan R, Jayakar B. Anti-ulcer effect of Nigella sativa Linn against gastric ulcers in rats. Curr Sci 2002; 82:177-179.
    • (2002) Curr Sci , vol.82 , pp. 177-179
    • Rajkapoor, B.1    Anandan, R.2    Jayakar, B.3
  • 29
    • 79151470509 scopus 로고    scopus 로고
    • Anti asthmatic effect of Nigella sativa in airways of asthmatic patients
    • Boskabady MH, Mohsenpoor N, Takaloo L. Anti asthmatic effect of Nigella sativa in airways of asthmatic patients. Phytomedicine 2010; 17:707713.
    • (2010) Phytomedicine , vol.17
    • Boskabady, M.H.1    Mohsenpoor, N.2    Takaloo, L.3
  • 31
    • 27744476617 scopus 로고    scopus 로고
    • Immunomodulatory and therapeutic properties of the Nigella sativa L. Seed
    • Salem ML. Immunomodulatory and therapeutic properties of the Nigella sativa L. seed. Int Immunopharmacol 2005; 5:1749-1770.
    • (2005) Int Immunopharmacol , vol.5 , pp. 1749-1770
    • Salem, M.L.1
  • 32
    • 77956282108 scopus 로고    scopus 로고
    • Nigella sativa modulates splenocyte proliferation, Th1/Th2 cytokine profile, macrophage function and NK antitumor activity
    • Majdalawieh AF, Hmaidan R, Carr RI. Nigella sativa modulates splenocyte proliferation, Th1/Th2 cytokine profile, macrophage function and NK antitumor activity. J Ethnopharmacol 2010; 131:268275.
    • (2010) J Ethnopharmacol , vol.131
    • Majdalawieh, A.F.1    Hmaidan, R.2    Carr, R.I.3
  • 33
    • 0033059343 scopus 로고    scopus 로고
    • Chemical composition and medicinal properties of Nigella sativa Linn
    • Khan MR. Chemical composition and medicinal properties of Nigella sativa Linn. Inflammopharmacology 1999; 7:13-35.
    • (1999) Inflammopharmacology , vol.7 , pp. 13-35
    • Khan, M.R.1
  • 34
    • 79952349582 scopus 로고    scopus 로고
    • Comparative gastroprotective effects of natural honey, Nigella sativa and cimetidine against acetylsalicylic acid induced gastric ulcer in albino rats
    • Bukhari MH, Khalil J, Qamar S, Qamar Z, Zahid M, Ansari N, et al. Comparative gastroprotective effects of natural honey, Nigella sativa and cimetidine against acetylsalicylic acid induced gastric ulcer in albino rats. J Coll Physicians Surg Pak 2011; 21:151156.
    • (2011) J Coll Physicians Surg Pak , vol.21
    • Bukhari, M.H.1    Khalil, J.2    Qamar, S.3    Qamar, Z.4    Zahid, M.5    Ansari, N.6
  • 35
    • 77957603475 scopus 로고    scopus 로고
    • Cancer chemopreventive potential of volatile oil from black cumin seeds, Nigella sativa L., in a rat multi-organ carcinogenesis bioassay
    • Salim EI. Cancer chemopreventive potential of volatile oil from black cumin seeds, Nigella sativa L., in a rat multi-organ carcinogenesis bioassay. Oncol Lett 2010; 1:913-924.
    • (2010) Oncol Lett , vol.1 , pp. 913-924
    • Salim, E.I.1
  • 36
    • 84901233944 scopus 로고    scopus 로고
    • Effects of Nigella sativa L. Seed oil on abnormal semen quality in infertile men: A randomized, double-blind, placebo-controlled clinical trial
    • Kolahdooz M, Nasri S, Modarres SZ, Kianbakht S, Huseini HF. Effects of Nigella sativa L. seed oil on abnormal semen quality in infertile men: A randomized, double-blind, placebo-controlled clinical trial. Phytomedicine 2014; 21:901-905.
    • (2014) Phytomedicine , vol.21 , pp. 901-905
    • Kolahdooz, M.1    Nasri, S.2    Modarres, S.Z.3    Kianbakht, S.4    Huseini, H.F.5
  • 37
    • 79960732771 scopus 로고    scopus 로고
    • Influence of black cumin fixed and essential oil supplementation on markers of myocardial necrosis in normal and diabetic rats
    • Sultan MT, Butt MS, Anjum FM, Jamil A. Influence of black cumin fixed and essential oil supplementation on markers of myocardial necrosis in normal and diabetic rats. Pak J Nutr 2009; 8:1450-1455.
    • (2009) Pak J Nutr , vol.8 , pp. 1450-1455
    • Sultan, M.T.1    Butt, M.S.2    Anjum, F.M.3    Jamil, A.4
  • 38
    • 84930871495 scopus 로고    scopus 로고
    • Effects of the hydroalcoholic extract of Nigella sativa on scopolamineinduced spatial memory impairment in rats and its possible mechanism
    • Hosseini M, Mohammadpour T, Karami R, Rajaei Z, Sadeghnia HR, Soukhtanloo M. Effects of the hydroalcoholic extract of Nigella sativa on scopolamineinduced spatial memory impairment in rats and its possible mechanism. Chin J Integr Med 2014; 1-7.
    • (2014) Chin J Integr Med , pp. 1-7
    • Hosseini, M.1    Mohammadpour, T.2    Karami, R.3    Rajaei, Z.4    Sadeghnia, H.R.5    Soukhtanloo, M.6
  • 39
    • 84874462108 scopus 로고    scopus 로고
    • Effect of aqueous and ethanolic extracts of Nigella sativa seeds on milk production in rats
    • Hosseinzadeh H, Tafaghodi M, Mosavi MJ, Taghiabadi E. Effect of aqueous and ethanolic extracts of Nigella sativa seeds on milk production in rats. J Acupunct Meridian Stud 2013; 6:18-23.
    • (2013) J Acupunct Meridian Stud , vol.6 , pp. 18-23
    • Hosseinzadeh, H.1    Tafaghodi, M.2    Mosavi, M.J.3    Taghiabadi, E.4
  • 40
    • 34547395342 scopus 로고    scopus 로고
    • Effect of thymoquinone and Nigella sativa seeds oil on lipid peroxidation level during global cerebral ischemia-reperfusion injury in rat hippocampus
    • Hosseinzadeh H, Parvardeh S, Asl MN, Sadeghnia HR, Ziaee T. Effect of thymoquinone and Nigella sativa seeds oil on lipid peroxidation level during global cerebral ischemia-reperfusion injury in rat hippocampus. Phytomedicine 2007; 14: 621-627.
    • (2007) Phytomedicine , vol.14 , pp. 621-627
    • Hosseinzadeh, H.1    Parvardeh, S.2    Asl, M.N.3    Sadeghnia, H.R.4    Ziaee, T.5
  • 41
    • 34548661065 scopus 로고    scopus 로고
    • Antibacterial activity of total extracts and essential oil of Nigella sativa L. Seeds in mice
    • Hosseinzadeh H, Fazly Bazzaz BS, Motevaly Haghi M. Antibacterial activity of total extracts and essential oil of Nigella sativa L. seeds in mice, Pharmacol online 2007; 2: 429-435.
    • (2007) Pharmacol Online , vol.2 , pp. 429-435
    • Hosseinzadeh, H.1    Fazly Bazzaz, B.S.2    Motevaly Haghi, M.3
  • 43
    • 0034286955 scopus 로고    scopus 로고
    • Protective effect of black seed oil from Nigella sativa against murine cytomegalovirus infection
    • Salem ML, Hossain MS. Protective effect of black seed oil from Nigella sativa against murine cytomegalovirus infection. Int J Immunopharmacol 2000; 22:729-740.
    • (2000) Int J Immunopharmacol , vol.22 , pp. 729-740
    • Salem, M.L.1    Hossain, M.S.2
  • 44
    • 0034026567 scopus 로고    scopus 로고
    • Antimicrobial agents from plants: Antibacterial activity of plant volatile oils
    • Dorman HJ, Deans SG. Antimicrobial agents from plants: antibacterial activity of plant volatile oils. J Appl Microbiol 2000; 88:308-316.
    • (2000) J Appl Microbiol , vol.88 , pp. 308-316
    • Dorman, H.J.1    Deans, S.G.2
  • 45
    • 0033945636 scopus 로고    scopus 로고
    • Antimicrobial effect of crude extracts of Nigella sativa on multiple antibiotics-resistant bacteria
    • Morsi NM. Antimicrobial effect of crude extracts of Nigella sativa on multiple antibiotics-resistant bacteria. Acta Microbiol Pol 2000; 49:63-74.
    • (2000) Acta Microbiol Pol , vol.49 , pp. 63-74
    • Morsi, N.M.1
  • 46
    • 68949135990 scopus 로고    scopus 로고
    • Anti-bacterial activity of Nigella sativa against clinical isolates of methicillin resistant Staphylococcus aureus
    • Hannan A, Saleem S, Chaudhary S, Barkaat M, Arshad MU. Anti-bacterial activity of Nigella sativa against clinical isolates of methicillin resistant Staphylococcus aureus. J Ayub Med Coll Abbottabad 2008; 20:72-74.
    • (2008) J Ayub Med Coll Abbottabad , vol.20 , pp. 72-74
    • Hannan, A.1    Saleem, S.2    Chaudhary, S.3    Barkaat, M.4    Arshad, M.U.5
  • 47
    • 79960294559 scopus 로고    scopus 로고
    • Detection of the antibacterial effect of Nigella sativa ground seeds with water
    • Bakathir HA, Abbas NA. Detection of the antibacterial effect of Nigella sativa ground seeds with water. Afr J Tradit Compl Altern Med 2011; 8:159-164.
    • (2011) Afr J Tradit Compl Altern Med , vol.8 , pp. 159-164
    • Bakathir, H.A.1    Abbas, N.A.2
  • 48
    • 84922372841 scopus 로고    scopus 로고
    • A investigational of antibacterial activities of Nigella sativa on mastaitis in dairy crossbred cows
    • Monika T, Sasikala P, Vijaya Bhaskara Reddy M. A investigational of antibacterial activities of Nigella sativa on mastaitis in dairy crossbred cows. Int J Adv Technical Res 2013; 3:263-272.
    • (2013) Int J Adv Technical Res , vol.3 , pp. 263-272
    • Monika, T.1    Sasikala, P.2    Vijaya Bhaskara Reddy, M.3
  • 49
    • 0025914525 scopus 로고
    • Studies on the antimicrobial activity of Nigella sativa seed (Black cumin)
    • Hanafy MS, Hatem ME. Studies on the antimicrobial activity of Nigella sativa seed (black cumin). J Ethnopharmacol 1991; 34:275-278.
    • (1991) J Ethnopharmacol , vol.34 , pp. 275-278
    • Hanafy, M.S.1    Hatem, M.E.2
  • 50
    • 10944240179 scopus 로고    scopus 로고
    • Antibacterial effect of black seed oil on Listeria monocytogenes
    • Nair MKM, Vasudevan P, Venkitanarayanan K. Antibacterial effect of black seed oil on Listeria monocytogenes. Food Cont 2005; 16:395-398.
    • (2005) Food Cont , vol.16 , pp. 395-398
    • Nair, M.1    Vasudevan, P.2    Venkitanarayanan, K.3
  • 51
    • 79953842455 scopus 로고    scopus 로고
    • Antibacterial activity of Thymoquinone, an active principle of Nigella sativa and its potency to prevent bacterial biofilm formation
    • Chaieb K, Kouidhi B, Jrah H, Mahdouani K, Bakhrouf A. Antibacterial activity of Thymoquinone, an active principle of Nigella sativa and its potency to prevent bacterial biofilm formation. BMC Complement Altern Med 2011; 11:1-6.
    • (2011) BMC Complement Altern Med , vol.11 , pp. 1-6
    • Chaieb, K.1    Kouidhi, B.2    Jrah, H.3    Mahdouani, K.4    Bakhrouf, A.5
  • 52
    • 80051789961 scopus 로고    scopus 로고
    • Chemical composition, antimicrobial potential against cariogenic bacteria and cytotoxic activity of Tunisian Nigella sativa essential oil and thymoquinone
    • Harzallah HJ, Kouidhi B, Flamini G, Bakhrouf A, Mahjoub T. Chemical composition, antimicrobial potential against cariogenic bacteria and cytotoxic activity of Tunisian Nigella sativa essential oil and thymoquinone. Food Chem 2011; 129:1469-1474.
    • (2011) Food Chem , vol.129 , pp. 1469-1474
    • Harzallah, H.J.1    Kouidhi, B.2    Flamini, G.3    Bakhrouf, A.4    Mahjoub, T.5
  • 53
    • 84872319852 scopus 로고    scopus 로고
    • Anti microbial activity of Nigella sativa seed extract
    • Hasan NA, Nawahwi MZ, Malek, HA. Anti microbial activity of Nigella sativa seed extract. Sains Malaysiana 2013; 42: 143-147.
    • (2013) Sains Malaysiana , vol.42 , pp. 143-147
    • Hasan, N.A.1    Nawahwi, M.Z.2    Malek, H.A.3
  • 54
    • 84874878294 scopus 로고    scopus 로고
    • Entrapment of seed extract of Nigella sativa into thermosensitive (NIPAAm-Co-VP) co-polymeric micelles and its antibacterial activity
    • Deepak SS, Sikender M, Garg V, Samim M. Entrapment of seed extract of Nigella sativa into thermosensitive (NIPAAm-Co-VP) co-polymeric micelles and its antibacterial activity. Int J Pharm Sci Drug Res 2011; 3:246-252.
    • (2011) Int J Pharm Sci Drug Res , vol.3 , pp. 246-252
    • Deepak, S.S.1    Sikender, M.2    Garg, V.3    Samim, M.4
  • 55
    • 80054016441 scopus 로고    scopus 로고
    • Effect of thymoquinone on oxidative stress in Escherichia coli-Induced Pyelonephritis in Rats
    • Evirgen O, Gokçe A, Ozturk OH, Nacar E, Onlen Y, Ozer B, et al. Effect of thymoquinone on oxidative stress in Escherichia coli-Induced Pyelonephritis in Rats. Curr Ther Res Clin Exp 2011; 72:204-215.
    • (2011) Curr Ther Res Clin Exp , vol.72 , pp. 204-215
    • Evirgen, O.1    Gokçe, A.2    Ozturk, O.H.3    Nacar, E.4    Onlen, Y.5    Ozer, B.6
  • 57
    • 80155143566 scopus 로고    scopus 로고
    • Effect of Hibiscus sabdariffa extract and Nigella sativa oil on the growth and aflatoxin B
    • El-Nagerabia SA, Al-Bahryb SN, Elshafieb AE, AlHilalib S. Effect of Hibiscus sabdariffa extract and Nigella sativa oil on the growth and aflatoxin B1 production of Aspergillus flavus and Aspergillus parasiticus strains. Food Cont 2012; 25:59-63.
    • (2012) Food Cont , vol.25 , pp. 59-63
    • El-Nagerabia, S.A.1    Al-Bahryb, S.N.2    Elshafieb, A.E.3    Alhilalib, S.4
  • 58
    • 85006020808 scopus 로고    scopus 로고
    • Chemical composition and antidermatophytic activity of Nigella sativa essential oil
    • Sunita M, Meenakshi SH. Chemical composition and antidermatophytic activity of Nigella sativa essential oil. Afr J Pharm Pharacol 2013; 7:12861292.
    • (2013) Afr J Pharm Pharacol , vol.7
    • Sunita, M.1    Meenakshi, S.H.2
  • 59
    • 0029846182 scopus 로고    scopus 로고
    • The involvement of nitric oxide in the anti-Candida albicans activity of rat neutrophils
    • Fierro IM, Barja-Fidalgo C, Cunha FQ, Ferreira SH. The involvement of nitric oxide in the anti-Candida albicans activity of rat neutrophils. Immunology 1996; 89:295-300.
    • (1996) Immunology , vol.89 , pp. 295-300
    • Fierro, I.M.1    Barja-Fidalgo, C.2    Cunha, F.Q.3    Ferreira, S.H.4
  • 60
    • 0037326010 scopus 로고    scopus 로고
    • The in vivo antifungal activity of the aqueous extract from Nigella sativa seeds
    • Khan MA, Ashfaq MK, Zuberi HS, Mahmood MS, Gilani AH. The in vivo antifungal activity of the aqueous extract from Nigella sativa seeds. Phytother Res 2003; 17:183-186.
    • (2003) Phytother Res , vol.17 , pp. 183-186
    • Khan, M.A.1    Ashfaq, M.K.2    Zuberi, H.S.3    Mahmood, M.S.4    Gilani, A.H.5
  • 61
    • 84886379004 scopus 로고    scopus 로고
    • An alternative treatment for Candida infections with Nigella sativa extracts Eur
    • Bita A, Rosu AF, Calina D, Rosu L, Zlatian O, Dindere C, et al. An alternative treatment for Candida infections with Nigella sativa extracts Eur J Hosp Pharm 2012; 19:162.
    • (2012) J Hosp Pharm , vol.19 , pp. 162
    • Bita, A.1    Rosu, A.F.2    Calina, D.3    Rosu, L.4    Zlatian, O.5    Dindere, C.6
  • 62
    • 0036136661 scopus 로고    scopus 로고
    • The effect of Nigella sativa oil against the liver damage induced by Schistosoma mansoni infection in mice
    • Mahmoud MR, El-Abhar HS, Saleh S. The effect of Nigella sativa oil against the liver damage induced by Schistosoma mansoni infection in mice. J Ethnopharmacol 2002; 79:1-11.
    • (2002) J Ethnopharmacol , vol.79 , pp. 1-11
    • Mahmoud, M.R.1    El-Abhar, H.S.2    Saleh, S.3
  • 63
    • 0037177574 scopus 로고    scopus 로고
    • Cytogenetic studies on Nigella sativa seeds extract and thymoquinone on mouse cells infected with schistosomiasis using karyotyping
    • Aboul-Ela EI. Cytogenetic studies on Nigella sativa seeds extract and thymoquinone on mouse cells infected with schistosomiasis using karyotyping. Mutat Res 2002; 516: 11-17.
    • (2002) Mutat Res , vol.516 , pp. 11-17
    • Aboul-Ela, E.I.1
  • 65
    • 40949149450 scopus 로고    scopus 로고
    • The effect of antioxidant properties of aqueous garlic extract and Nigella sativa as antischistosomiasis agents in mice
    • Shenawy El, Nahla S, Soliman MF, Reyad SI. The effect of antioxidant properties of aqueous garlic extract and Nigella sativa as antischistosomiasis agents in mice. Rev Inst Med Trop Sao Paulo 2008; 50:29-36.
    • (2008) Rev Inst Med Trop Sao Paulo , vol.50 , pp. 29-36
    • El, S.1    Nahla, S.2    Soliman, M.F.3    Reyad, S.I.4
  • 66
    • 0030947119 scopus 로고    scopus 로고
    • Oxidants and antioxidants in viral diseases: Disease mechanisms and metabolic regulation
    • Peterhans E. Oxidants and antioxidants in viral diseases: disease mechanisms and metabolic regulation. J Nutr 1997; 127:962S-965S.
    • (1997) J Nutr , vol.127 , pp. 962S-965S
    • Peterhans, E.1
  • 67
    • 0034286992 scopus 로고    scopus 로고
    • In vivo acute depletion of CD8 (+) T cells before murine cytomegalovirus infection upregulated innate antiviral activity of natural killer cells
    • Salem ML, Hossain MS. In vivo acute depletion of CD8 (+) T cells before murine cytomegalovirus infection upregulated innate antiviral activity of natural killer cells. Int J Immunopharmacol 2000; 22:707-718.
    • (2000) Int J Immunopharmacol , vol.22 , pp. 707-718
    • Salem, M.L.1    Hossain, M.S.2
  • 68
    • 84877280196 scopus 로고    scopus 로고
    • Effects of Nigella sativa on outcome of hepatitis C in Egypt
    • Barakat EM, El Wakeel LM, Hagag RS. Effects of Nigella sativa on outcome of hepatitis C in Egypt. World J Gastroenterol 2013; 19:2529-2536.
    • (2013) World J Gastroenterol , vol.19 , pp. 2529-2536
    • Barakat, E.M.1    El Wakeel, L.M.2    Hagag, R.S.3
  • 69
    • 0025826841 scopus 로고
    • Field trial of Saussurea lappa roots against nematodes and Nigella sativa seeds against cestodes in children
    • Akhtar MS, Riffat S. Field trial of Saussurea lappa roots against nematodes and Nigella sativa seeds against cestodes in children J Pak Med Assoc 1991; 41:185-187.
    • (1991) J Pak Med Assoc , vol.41 , pp. 185-187
    • Akhtar, M.S.1    Riffat, S.2
  • 70
    • 79959380543 scopus 로고    scopus 로고
    • Antimalarial and antioxidant activities of methanolic extract of Nigella sativa seeds (Black cumin) in mice infected with Plasmodium yoelli nigeriensis
    • Okeola VO, Adaramoye OA, Nneji CM, Falade CO, Farombi EO, Ademowo OG. Antimalarial and antioxidant activities of methanolic extract of Nigella sativa seeds (black cumin) in mice infected with Plasmodium yoelli nigeriensis. Parasitol Res 2011; 108:1507-1512.
    • (2011) Parasitol Res , vol.108 , pp. 1507-1512
    • Okeola, V.O.1    Adaramoye, O.A.2    Nneji, C.M.3    Falade, C.O.4    Farombi, E.O.5    Ademowo, O.G.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.