Effect of Thymoquinone on Oxidative Stress in Escherichia coli-Induced Pyelonephritis in Rats

Current Therapeutic Research - Clinical and Experimental

Volumn 72, Issue 5, 2011, Pages 204-215

  Evirgen, Omer ^a   Gökçe, Ahmet ^a   Ozturk, Oktay Hasan ^a   Nacar, Emel ^a   Onlen, Yusuf ^a   Ozer, Burcin ^a   Motor, Vicdan Koksaldi ^a  

^a MUSTAFA KEMAL UNIVERSITY   (Turkey)

Author keywords

Kidney; Oxidative stress; Pyelonephritis; Thymoquinone; Wistar rats

Indexed keywords

CATALASE; GLUTATHIONE PEROXIDASE; MALONALDEHYDE; SUPEROXIDE DISMUTASE; THYMOQUINONE;

ACUTE PYELONEPHRITIS; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTIOXIDANT ACTIVITY; ARTICLE; BACTERIAL STRAIN; BODY WEIGHT; COLONY FORMING UNIT; CONTROLLED STUDY; DRUG EFFECT; DRUG EFFICACY; ENZYME ACTIVITY; ESCHERICHIA COLI; HISTOPATHOLOGY; INOCULATION; KIDNEY PARENCHYMA; MALE; NONHUMAN; OXIDATIVE STRESS; PRIORITY JOURNAL; RAT; TREATMENT OUTCOME; URETHRAL CATHETERIZATION;

EID: 80054016441     PISSN: 0011393X     EISSN: 18790313     Source Type: Journal    
DOI: 10.1016/j.curtheres.2011.09.002     Document Type: Article

References (33)

1. Sobel J.D., Kaye D. Urinary tract infections. Principles and Practice of Infectious Diseases 2010, 957-985. Churchill Livingstone, Philadelphia. 7th ed. G.L. Mandell, J.E. Bennett, R. Dolin (Eds.).
2. Leroy S., Chalumeau M., Ulinski T., et al. Impressive renal damage after acute pyelonephritis in a child. Pediatr Nephrol 2010, 25:1365-1368.
3. Haraoka M., Matsumoto T., Takahashi K., et al. Suppression of renal scarring by prednisolone combined with ciprofloxacin in ascending pyelonephritis in rats. J Urol 1994, 151:1078-1080.
4. Garin E.H., Olavarria F., Garcia Nieto V., et al. Clinical significance of primary vesicoureteral reflux and urinary antibiotic prophylaxis after acute pyelonephritis: a multicenter, randomized, controlled study. Pediatrics 2006, 117:626-632.
5. Gordon I., Barkovics M., Pindoria S., et al. Primary vesicoureteric reflux as a predictor of renal damage in children hospitalized with urinary tract infection: a systematic review and meta-analysis. J Am Soc Nephrol 2003, 14:739-744.
6. Glauser M.P., Meylan P., Bille J. The inflammatory response and tissue damage. The example of renal scars following acute renal infection. Pediatr Nephrol 1987, 1:615-622.
7. Scholes D., Hooton T.M., Roberts P.L., et al. Risk factors associated with acute pyelonephritis in healthy women. Ann Intern Med 2005, 142:20-27.
8. Mundi H., Bjorksten B., Svanborg C., et al. Extracellular release of reactive oxygen species from human neutrophils upon interaction with Escherichia coli strains causing renal scarring. Infect Immun 1991, 59:4168-4172.
9. Yagmurlu A., Boleken M.E., Ertoy D., et al. Preventive effect of pentoxifylline on renal scarring in rat model of pyelonephritis. Urology 2003, 61:1037-1041.
10. Bennett R.T., Mazzaccaro R.J., Chopra N., et al. Suppression of renal inflammation with vitamins A and E in ascending pyelonephritis in rats. J Urol 1999, 161:1681-1684.
11. El-Kadi A., Kandil O. The black seed (Nigella sativa) and immunity: its effect on human T cell subset. Fed Proc 1987, 46:1222.
12. Hanafy M.S., Hatem M.E. Studies on the antimicrobial activity of Nigella sativa seed (black cumin). J Ethnopharmacol 1991, 34:275-278.
13. Kanter M., Coskun O., Korkmaz A., Oter S. Effects of Nigella sativa on oxidative stress and beta-cell damage in streptozotocin-induced diabetic rats. Anat Rec A Discov Mol Cell Evol Biol 2004, 279:685-691.
14. Kanter M., Meral I., Yener Z., et al. Partial regeneration/proliferation of the beta-cells in the islets of Langerhans by Nigella sativa L. in streptozotocin-induced diabetic rats. Tohoku J Exp Med 2003, 201:213-219.
15. Kanter M., Coskun O., Uysal H. The antioxidative and antihistaminic effect of Nigella sativa and its major constituent, thymoquinone on ethanol-induced gastric mucosal damage. Arch Toxicol 2006, 80:217-224.
16. Badary O.A., Nagi M.N., al-Shabanah O.A., et al. Thymoquinone ameliorates the nephrotoxicity induced by cisplatin in rodents and potentiates its antitumor activity. Can J Physiol Pharmacol 1997, 75:1356-1361.
17. Houghton P.J., Zarka R., de las Heras B., Hoult J.R. Fixed oil of Nigella sativa and derived thymoquinone inhibit eicosanoid generation in leukocytes and membrane lipid peroxidation. Planta Med 1995, 61:33-36.
18. Al-Ali A., Alkhawajah A.A., Randhawa M.A., Shaikh N.A. Oral and intraperitoneal LD50 of thymoquinone, an active principle of Nigella sativa, in mice and rats. J Ayub Med Coll Abbottabad 2008, 20:25-27.
19. Esterbauer H., Cheeseman K.H. Determination of aldehydic lipid peroxidation products: malonaldehyde and 4-hydroxynonenal. Methods Enzymol 1990, 186:407-421.
20. Aebi H. Catalase. Methods of Enzymatic Analysis 1974, 673-677. Academic Press, New York. H.U. Bergmeyer (Ed.).
21. Paglia D.E., Valentine W.N. Studies on the quantitative and qualitative characterization of erythrocyte glutathione peroxidase. J Lab Clin Med 1967, 70:158-169.
22. Lowry O.H., Rosebrough N.J., Farr A.L., Randall R.J. Protein measurement with the Folin phenol reagent. J Biol Chem 1951, 193:265-275.
23. Sun Y., Oberley L.W., Li Y. A simple method for clinical assay of superoxide dismutase. Clin Chem 1988, 34:497-500.
24. Karahan I., Atessahin A., Yilmaz S., et al. Protective effect of lycopene on gentamicin-induced oxidative stress and nephrotoxicity in rats. Toxicology 2005, 215:198-204.
25. Celik S., Gorur S., Aslantas O., et al. Caffeic acid phenethyl ester suppresses oxidative stress in Escherichia coli-induced pyelonephritis in rats. Mol Cell Biochem 2007, 297:131-138.
26. Kucheria R., Dasgupta P., Sacks S.H., et al. Urinary tract infections: new insights into a common problem. Postgrad Med J 2005, 81:83-86.
27. Badary O.A., Taha R.A., Gamal el-Din A.M., Abdel-Wahab M.H. Thymoquinone is a potent superoxide anion scavenger. Drug Chem Toxicol 2003, 26:87-98.
28. Nagi M.N., Mansour M.A. Protective effect of thymoquinone against doxorubicin-induced cardiotoxicity in rats: a possible mechanism of protection. Pharmacol Res 2000, 41:283-289.
29. Pompella A. Biochemistry and histochemistry of oxidant stress and lipid peroxidation. Int J Vitam Nutr Res 1997, 67:289-297.
30. Abdelmeguid N.E., Fakhoury R., Kamal S.M., Al Wafai R.J. Effects of Nigella sativa and thymoquinone on biochemical and subcellular changes in pancreatic beta-cells of streptozotocin-induced diabetic rats. J Diabetes 2010, 2:256-266.
31. Fouda A.M., Daba M.H., Dahab G.M., Sharaf El-Din O.A. Thymoquinone ameliorates renal oxidative damage and proliferative response induced by mercuric chloride in rats. Basic Clin Pharmacol Toxicol 2008, 103:109-118.
32. Kanter M. Protective effects of thymoquinone on streptozotocin-induced diabetic nephropathy. J Mol Histol 2009, 40:107-115.
33. Sayed-Ahmed M.M., Nagi M.N. Thymoquinone supplementation prevents the development of gentamicin-induced acute renal toxicity in rats. Clin Exp Pharmacol Physiol 2007, 34:399-405.