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Volumn 11, Issue 4, 2005, Pages

Intracerebroventricular administration of thymoquinone, the major constituent of Nigella sativa seeds, suppresses epileptic seizures in rats

Author keywords

Anticonvulsant; BZD receptor; Nigella sativa; Opioid receptors; Pentylenetetrazole; Thymoquinone

Indexed keywords

DIAZEPAM; FLUMAZENIL; KETAMINE; NALOXONE; NIGELLA SATIVA EXTRACT; OPIATE RECEPTOR; PENTETRAZOLE; THYMOQUINONE; XYLAZINE;

EID: 17444422880     PISSN: 12341010     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article
Times cited : (90)

References (20)
  • 2
    • 0007552836 scopus 로고    scopus 로고
    • Clinical importance of Nigella sativa L. A review
    • Siddiqui AA, Sharma PKR: Clinical importance of Nigella sativa L. a review. Hamdard Medicus, 1996; 39: 38-42
    • (1996) Hamdard Medicus , vol.39 , pp. 38-42
    • Siddiqui, A.A.1    Sharma, P.K.R.2
  • 3
    • 0031878048 scopus 로고    scopus 로고
    • The in vitro anti-tumor activity of some crude and purified components of blackseed, Nigella sativa L
    • Worthen DR, Ghoshe, OA, Crooks PA: The in vitro anti-tumor activity of some crude and purified components of blackseed, Nigella sativa L. Anticancer Res, 1998; 18: 1527-32
    • (1998) Anticancer Res , vol.18 , pp. 1527-1532
    • Worthen, D.R.1    Ghoshe, O.A.2    Crooks, P.A.3
  • 5
    • 0036135452 scopus 로고    scopus 로고
    • Seed yield, yield components, oil content and essential oil content and composition of Nigella sativa L. and Nigella damascene L
    • Filippo D'Antuono L, Moretti A, Lovato Antonio FS: Seed yield, yield components, oil content and essential oil content and composition of Nigella sativa L. and Nigella damascene L. Indust Crops Prod, 2002; 15: 59-69
    • (2002) Indust Crops Prod , vol.15 , pp. 59-69
    • Filippo D'Antuono, L.1    Moretti, A.2    Lovato Antonio, F.S.3
  • 6
    • 0034648056 scopus 로고    scopus 로고
    • Antinociceptive effects of Nigeflla sativa oil and its major component, thymoquinone, in mice
    • Abdel-Fattah AFM, Matsumoto K, Watanabe H: Antinociceptive effects of Nigeflla sativa oil and its major component, thymoquinone, in mice. Eur J Pharmacol, 2000; 400: 89-97
    • (2000) Eur J Pharmacol , vol.400 , pp. 89-97
    • Abdel-Fattah, A.F.M.1    Matsumoto, K.2    Watanabe, H.3
  • 7
    • 0028852880 scopus 로고
    • Fixed oil of Nigella sativa and derived thymoquinone inhibit eicosanoid generation in leukocytes and membrane lipid peroxidation
    • Houghton PI, Zarka R, De las Heras B, Hoult RS: Fixed oil of Nigella sativa and derived thymoquinone inhibit eicosanoid generation in leukocytes and membrane lipid peroxidation. Planta Med, 1995; 61: 33-36
    • (1995) Planta Med , vol.61 , pp. 33-36
    • Houghton, P.I.1    Zarka, R.2    De Las Heras, B.3    Hoult, R.S.4
  • 8
    • 0009463944 scopus 로고
    • Effect of some Nigella sativa constituents on chemical cardnogenesis in hamster cheek pouch
    • Hassan M, El-Dakhakhny M: Effect of some Nigella sativa constituents on chemical cardnogenesis in hamster cheek pouch. J Egypt Soci Pharmacol Exp Ther, 1992; 11: 675-77
    • (1992) J Egypt Soci Pharmacol Exp Ther , vol.11 , pp. 675-677
    • Hassan, M.1    El-Dakhakhny, M.2
  • 9
    • 0027379097 scopus 로고
    • CNS and analgesic studies on Nigella sativa
    • Khanna T, Zaidi FA, Dandiya PC: CNS and analgesic studies on Nigella sativa. Fitoterapia, 1993; 64: 407-10
    • (1993) Fitoterapia , vol.64 , pp. 407-410
    • Khanna, T.1    Zaidi, F.A.2    Dandiya, P.C.3
  • 10
    • 1042303460 scopus 로고    scopus 로고
    • Anticonvulsant effect of thymoquinone, the major constituent of Nigella sativa seeds, in mice
    • Hosseinzadeh H, Parvardeh S: Anticonvulsant effect of thymoquinone, the major constituent of Nigella sativa seeds, in mice. Phytomedicine, 2004; 11: 56-64
    • (2004) Phytomedicine , vol.11 , pp. 56-64
    • Hosseinzadeh, H.1    Parvardeh, S.2
  • 12
    • 0036271283 scopus 로고    scopus 로고
    • Anticonvulsant effects of aqueous and ethanolic extracts of Crocus salivus L. stigmas in mice
    • Hosseinzadeh H, Khosravan V: Anticonvulsant effects of aqueous and ethanolic extracts of Crocus salivus L. stigmas in mice. Arch Irn Med, 2002; 5: 45-48
    • (2002) Arch Irn Med , vol.5 , pp. 45-48
    • Hosseinzadeh, H.1    Khosravan, V.2
  • 13
    • 1042274430 scopus 로고    scopus 로고
    • Anticonvulsant effects of Coriandrum salivum L. seeds extracts in mice
    • Hosseinzadeh H, Madanifard M: Anticonvulsant effects of Coriandrum salivum L. seeds extracts in mice. Arch Irn Med, 2000; 3: 182-84
    • (2000) Arch Irn Med , vol.3 , pp. 182-184
    • Hosseinzadeh, H.1    Madanifard, M.2
  • 14
    • 0022656375 scopus 로고
    • Intrinsic actions of the benzodiazepine receptor antagonist Ro 15-1788
    • File SE, Pellow S: Intrinsic actions of the benzodiazepine receptor antagonist Ro 15-1788. Psychopharmacoogyl, 1986; 88: 1-11
    • (1986) Psychopharmacoogyl , vol.88 , pp. 1-11
    • File, S.E.1    Pellow, S.2
  • 15
    • 0017647010 scopus 로고
    • Pentylenetetrazole and penicillin are selective antagonists of GABA-mediated post-synaptic inhibition in cultured mammalian neurons
    • Macdonald RL, Barker JL: Pentylenetetrazole and penicillin are selective antagonists of GABA-mediated post-synaptic inhibition in cultured mammalian neurons. Nature, 1977; 267: 720-22
    • (1977) Nature , vol.267 , pp. 720-722
    • Macdonald, R.L.1    Barker, J.L.2
  • 16
    • 0020045631 scopus 로고
    • 3H]-diazepam binding. In vitro, correlation with convulsant potency
    • 3H]-diazepam binding. In vitro, correlation with convulsant potency. Eur J Pharmacol, 1982; 78: 353-56
    • (1982) Eur J Pharmacol , vol.78 , pp. 353-356
    • Rehavi, M.1    Skolnick, P.2    Paul, S.M.3
  • 17
    • 0023903262 scopus 로고
    • Flumazenil: A preliminary review of its benzodiazepine antagonist properties, intrinsic activity and therapeutic use
    • Brogden RN, Goa KL: Flumazenil: a preliminary review of its benzodiazepine antagonist properties, intrinsic activity and therapeutic use. Drugs, 1988; 35: 448-67
    • (1988) Drugs , vol.35 , pp. 448-467
    • Brogden, R.N.1    Goa, K.L.2
  • 18
    • 0034678524 scopus 로고    scopus 로고
    • Effects of differential modulation of μ-, δ- and κ-opioid systems on bicuculline-induced convulsions in the mouse
    • Yajima Y, Naritaa M, Takahashi-Nakano Y et al: Effects of differential modulation of μ-, δ- and κ-opioid systems on bicuculline-induced convulsions in the mouse. Brain Res, 2000; 862: 120-26
    • (2000) Brain Res , vol.862 , pp. 120-126
    • Yajima, Y.1    Naritaa, M.2    Takahashi-Nakano, Y.3
  • 19
    • 0021745419 scopus 로고
    • Dynorphin reduces voltage-dependent calcium conductance of mouse dorsal root ganglion neurons
    • Werz RL, Macdonald MA: Dynorphin reduces voltage-dependent calcium conductance of mouse dorsal root ganglion neurons. Neuropept, 1984; 5: 253-56
    • (1984) Neuropept , vol.5 , pp. 253-256
    • Werz, R.L.1    Macdonald, M.A.2
  • 20
    • 0021883147 scopus 로고
    • Dynorphin and neoendorphin peptides decrease dorsal root ganglion neuron calcium-dependent action potential duration
    • Werz MA, Macdonald RL: Dynorphin and neoendorphin peptides decrease dorsal root ganglion neuron calcium-dependent action potential duration. J Pharmacol Exp Ther, 1985; 234: 49-56
    • (1985) J Pharmacol Exp Ther , vol.234 , pp. 49-56
    • Werz, M.A.1    Macdonald, R.L.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.