메뉴 건너뛰기




Volumn 10, Issue 2, 2015, Pages

Inactivation of dap12 in pmn inhibits trem1-mediated activation in rheumatoid arthritis

Author keywords

[No Author keywords available]

Indexed keywords

INTERLEUKIN 17; INTERLEUKIN 6; INTERLEUKIN 8; KILLER CELL ACTIVATING RECEPTOR ASSOCIATED PROTEIN; MITOGEN ACTIVATED PROTEIN KINASE; MITOGEN ACTIVATED PROTEIN KINASE 1; PROTEIN KINASE SYK; RANTES; TRIGGERING RECEPTOR EXPRESSED ON MYELOID CELLS 1; TUMOR NECROSIS FACTOR ALPHA; IMMUNOGLOBULIN RECEPTOR; MEMBRANE PROTEIN; SIGNAL TRANSDUCING ADAPTOR PROTEIN; TREM1 PROTEIN, HUMAN; TYROBP PROTEIN, HUMAN;

EID: 84922327075     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0115116     Document Type: Article
Times cited : (14)

References (53)
  • 1
    • 0034009870 scopus 로고    scopus 로고
    • Pathogenesis of bone erosions in rheumatoid arthritis
    • Goldring SR, Gravallese EM (2000) Pathogenesis of bone erosions in rheumatoid arthritis. Curr Opin Rheumatol 12: 195-199. doi: 10.1097/00002281-200005000-00006
    • (2000) Curr Opin Rheumatol , vol.12 , pp. 195-199
    • Goldring, S.R.1    Gravallese, E.M.2
  • 2
    • 28544448518 scopus 로고    scopus 로고
    • Rheumatic diseases: The effects of inflammation on bone
    • Walsh NC, Crotti TN, Goldring SR, Gravallese EM (2005) Rheumatic diseases: the effects of inflammation on bone. Immunol Rev 208: 228-251. doi: 10.1111/j.0105-2896.2005.00338.x
    • (2005) Immunol Rev , vol.208 , pp. 228-251
    • Walsh, N.C.1    Crotti, T.N.2    Goldring, S.R.3    Gravallese, E.M.4
  • 3
    • 77953251575 scopus 로고    scopus 로고
    • Innate immunity and rheumatoid arthritis
    • Gierut A, Perlman H, Pope RM (2010) Innate immunity and rheumatoid arthritis. Rheum Dis Clin North Am 36: 271-296. doi: 10.1016/j.rdc.2010.03.004
    • (2010) Rheum Dis Clin North Am , vol.36 , pp. 271-296
    • Gierut, A.1    Perlman, H.2    Pope, R.M.3
  • 4
    • 33344468233 scopus 로고    scopus 로고
    • Neutrophils and immunity: Challenges and opportunities
    • Nathan C (2006) Neutrophils and immunity: challenges and opportunities. Nat Rev Immunol 6: 173-182. doi: 10.1038/nri1785
    • (2006) Nat Rev Immunol , vol.6 , pp. 173-182
    • Nathan, C.1
  • 5
    • 0022536330 scopus 로고
    • In vivo induction of neutrophilia, lymphopenia, and diminution of neutrophil adhesion by stable analogs of prostaglandins E1, E2, and F2 alpha
    • Ulich TR, Dakay EB, Williams JH, Ni RX (1986) In vivo induction of neutrophilia, lymphopenia, and diminution of neutrophil adhesion by stable analogs of prostaglandins E1, E2, and F2 alpha. Am J Pathol 124: 53-58
    • (1986) Am J Pathol , vol.124 , pp. 53-58
    • Ulich, T.R.1    Dakay, E.B.2    Williams, J.H.3    Ni, R.X.4
  • 6
    • 11144299492 scopus 로고    scopus 로고
    • NK cell recognition
    • Lanier LL (2005) NK cell recognition. Annu Rev Immunol 23: 225-274. doi: 10.1146/annurev.immunol. 23.021704.115526
    • (2005) Annu Rev Immunol , vol.23 , pp. 225-274
    • Lanier, L.L.1
  • 7
    • 0034613151 scopus 로고    scopus 로고
    • Immune inhibitory receptors
    • Ravetch JV, Lanier LL (2000) Immune inhibitory receptors. Science 290: 84-89. doi: 10.1126/science. 290.5489.84
    • (2000) Science , vol.290 , pp. 84-89
    • Ravetch, J.V.1    Lanier, L.L.2
  • 8
    • 84868647589 scopus 로고    scopus 로고
    • The immunoreceptor tyrosine-based activation motif (ITAM)-related factors are increased in synovial tissue and vasculature of rheumatoid arthritic joints
    • Crotti TN, Dharmapatni AA, Alias E, Zannettino AC, Smith MD, et al. (2012) The immunoreceptor tyrosine-based activation motif (ITAM)-related factors are increased in synovial tissue and vasculature of rheumatoid arthritic joints. Arthritis Res Ther 14: R245. doi: 10.1186/ar4088
    • (2012) Arthritis Res Ther , vol.14 , pp. R245
    • Crotti, T.N.1    Dharmapatni, A.A.2    Alias, E.3    Zannettino, A.C.4    Smith, M.D.5
  • 9
    • 84887856706 scopus 로고    scopus 로고
    • CpG-oligodeoxynucleotide-induced TLR9 activation regulates macrophage TREM-1 expression and shedding
    • Molad Y, Pokroy-Shapira E, Carmon V (2013) CpG-oligodeoxynucleotide-induced TLR9 activation regulates macrophage TREM-1 expression and shedding. Innate Immun 19: 623-630. doi: 10.1177/1753425913476970
    • (2013) Innate Immun , vol.19 , pp. 623-630
    • Molad, Y.1    Pokroy-Shapira, E.2    Carmon, V.3
  • 10
    • 64049095240 scopus 로고    scopus 로고
    • TREM and TREM-like receptors in inflammation and disease
    • Ford JW, McVicar DW (2009) TREM and TREM-like receptors in inflammation and disease. Curr Opin Immunol 21: 38-46. doi: 10.1016/j.coi.2009.01.009
    • (2009) Curr Opin Immunol , vol.21 , pp. 38-46
    • Ford, J.W.1    McVicar, D.W.2
  • 11
    • 78049279379 scopus 로고    scopus 로고
    • Triggering receptor expressed on myeloid cells-1 as a new therapeutic target during inflammatory diseases
    • Derive M, Massin F, Gibot S (2010) Triggering receptor expressed on myeloid cells-1 as a new therapeutic target during inflammatory diseases. Self Nonself 1: 225-230. doi: 10.4161/self.1.3.12891
    • (2010) Self Nonself , vol.1 , pp. 225-230
    • Derive, M.1    Massin, F.2    Gibot, S.3
  • 12
    • 33846316333 scopus 로고    scopus 로고
    • The TREM receptor family and signal integration
    • Klesney-Tait J, Turnbull IR, Colonna M (2006) The TREM receptor family and signal integration. Nat Immunol 7: 1266-1273. doi: 10.1038/ni1411
    • (2006) Nat Immunol , vol.7 , pp. 1266-1273
    • Klesney-Tait, J.1    Turnbull, I.R.2    Colonna, M.3
  • 13
    • 40149105559 scopus 로고    scopus 로고
    • The TREM-1/DAP12 pathway
    • Tessarz AS, Cerwenka A (2008) The TREM-1/DAP12 pathway. Immunol Lett 116: 111-116. doi: 10. 1016/j.imlet.2007.11.021
    • (2008) Immunol Lett , vol.116 , pp. 111-116
    • Tessarz, A.S.1    Cerwenka, A.2
  • 14
    • 52949142215 scopus 로고    scopus 로고
    • From expression to signaling: Roles of TREM-1 and TREM-2 in innate immunity and bacterial infection
    • Sharif O, Knapp S (2008) From expression to signaling: roles of TREM-1 and TREM-2 in innate immunity and bacterial infection. Immunobiology 213: 701-713. doi: 10.1016/j.imbio.2008.07.008
    • (2008) Immunobiology , vol.213 , pp. 701-713
    • Sharif, O.1    Knapp, S.2
  • 15
    • 70449715678 scopus 로고    scopus 로고
    • Elevated synovial expression of triggering receptor expressed on myeloid cells 1 in patients with septic arthritis or rheumatoid arthritis
    • Collins CE, La DT, Yang HT, Massin F, Gibot S, et al. (2009) Elevated synovial expression of triggering receptor expressed on myeloid cells 1 in patients with septic arthritis or rheumatoid arthritis. Ann Rheum Dis 68: 1768-1774. doi: 10.1136/ard.2008.089557
    • (2009) Ann Rheum Dis , vol.68 , pp. 1768-1774
    • Collins, C.E.1    La, D.T.2    Yang, H.T.3    Massin, F.4    Gibot, S.5
  • 16
    • 73349100344 scopus 로고    scopus 로고
    • TREM-1 expression is increased in the synovium of rheumatoid arthritis patients and induces the expression of pro-inflammatory cytokines
    • Kuai J, Gregory B, Hill A, Pittman DD, Feldman JL, et al. (2009) TREM-1 expression is increased in the synovium of rheumatoid arthritis patients and induces the expression of pro-inflammatory cytokines. Rheumatology (Oxford) 48: 1352-1358. doi: 10.1093/rheumatology/kep235
    • (2009) Rheumatology (Oxford , vol.48 , pp. 1352-1358
    • Kuai, J.1    Gregory, B.2    Hill, A.3    Pittman, D.D.4    Feldman, J.L.5
  • 17
    • 66449085242 scopus 로고    scopus 로고
    • Intervention of an inflammation amplifier, triggering receptor expressed on myeloid cells 1, for treatment of autoimmune arthritis
    • Murakami Y, Akahoshi T, Aoki N, Toyomoto M, Miyasaka N, et al. (2009) Intervention of an inflammation amplifier, triggering receptor expressed on myeloid cells 1, for treatment of autoimmune arthritis. Arthritis Rheum 60: 1615-1623. doi: 10.1002/art.24554
    • (2009) Arthritis Rheum , vol.60 , pp. 1615-1623
    • Murakami, Y.1    Akahoshi, T.2    Aoki, N.3    Toyomoto, M.4    Miyasaka, N.5
  • 18
    • 34948821265 scopus 로고    scopus 로고
    • TREM-1-expressing intestinal macrophages crucially amplify chronic inflammation in experimental colitis and inflammatory bowel diseases
    • Schenk M, Bouchon A, Seibold F, Mueller C (2007) TREM-1-expressing intestinal macrophages crucially amplify chronic inflammation in experimental colitis and inflammatory bowel diseases. J Clin Invest 117: 3097-3106. doi: 10.1172/JCI30602
    • (2007) J Clin Invest , vol.117 , pp. 3097-3106
    • Schenk, M.1    Bouchon, A.2    Seibold, F.3    Mueller, C.4
  • 20
    • 21044454739 scopus 로고    scopus 로고
    • Neutrophil-derived cytokines: Potential therapeutic targets in inflammation
    • Kasama T, Miwa Y, Isozaki T, Odai T, Adachi M, et al. (2005) Neutrophil-derived cytokines: potential therapeutic targets in inflammation. Curr Drug Targets Inflamm Allergy 4: 273-279. doi: 10.2174/1568010054022114
    • (2005) Curr Drug Targets Inflamm Allergy , vol.4 , pp. 273-279
    • Kasama, T.1    Miwa, Y.2    Isozaki, T.3    Odai, T.4    Adachi, M.5
  • 21
    • 55849095891 scopus 로고    scopus 로고
    • Evidence that cytokines play a role in rheumatoid arthritis
    • Brennan FM, McInnes IB (2008) Evidence that cytokines play a role in rheumatoid arthritis. J Clin Invest 118: 3537-3545. doi: 10.1172/JCI36389
    • (2008) J Clin Invest , vol.118 , pp. 3537-3545
    • Brennan, F.M.1    McInnes, I.B.2
  • 22
    • 65149086162 scopus 로고    scopus 로고
    • A critical role for DAP10 and DAP12 in CD8+ T cellmediated tissue damage in large granular lymphocyte leukemia
    • Chen X, Bai F, Sokol L, Zhou J, Ren A, et al. (2009) A critical role for DAP10 and DAP12 in CD8+ T cellmediated tissue damage in large granular lymphocyte leukemia. Blood 113: 3226-3234. doi: 10.1182/blood-2008-07-168245
    • (2009) Blood , vol.113 , pp. 3226-3234
    • Chen, X.1    Bai, F.2    Sokol, L.3    Zhou, J.4    Ren, A.5
  • 23
    • 84887430236 scopus 로고    scopus 로고
    • Induction of myelodysplasia by myeloidderived suppressor cells
    • Chen X, Eksioglu EA, Zhou J, Zhang L, Djeu J, et al. (2013) Induction of myelodysplasia by myeloidderived suppressor cells. J Clin Invest. doi: 10.1172/JCI67580
    • J Clin Invest , vol.2013
    • Chen, X.1    Eksioglu, E.A.2    Zhou, J.3    Zhang, L.4    Djeu, J.5
  • 24
    • 0033850719 scopus 로고    scopus 로고
    • Expression of vascular endothelial growth factor by synovial fluid neutrophils in rheumatoid arthritis (RA
    • Kasama T, Kobayashi K, Yajima N, Shiozawa F, Yoda Y, et al. (2000) Expression of vascular endothelial growth factor by synovial fluid neutrophils in rheumatoid arthritis (RA). Clin Exp Immunol 121: 533-538. doi: 10.1046/j.1365-2249.2000.01272.x
    • (2000) Clin Exp Immunol , vol.121 , pp. 533-538
    • Kasama, T.1    Kobayashi, K.2    Yajima, N.3    Shiozawa, F.4    Yoda, Y.5
  • 25
    • 84895153556 scopus 로고    scopus 로고
    • Emerging cell and cytokine targets in rheumatoid arthritis
    • Burmester GR, Feist E, Dorner T (2014) Emerging cell and cytokine targets in rheumatoid arthritis. Nat Rev Rheumatol 10: 77-88. doi: 10.1038/nrrheum.2013.168
    • (2014) Nat Rev Rheumatol , vol.10 , pp. 77-88
    • Burmester, G.R.1    Feist, E.2    Dorner, T.3
  • 26
    • 1842611825 scopus 로고    scopus 로고
    • Biological mediators of acute inflammation
    • Rankin JA (2004) Biological mediators of acute inflammation. AACN Clin Issues 15: 3-17. doi: 10. 1097/00044067-200401000-00002
    • (2004) AACN Clin Issues , vol.15 , pp. 3-17
    • Rankin, J.A.1
  • 27
    • 0038603018 scopus 로고    scopus 로고
    • Exploring the reciprocal relationship between immunity and inflammation in chronic inflammatory arthritis
    • Cope AP (2003) Exploring the reciprocal relationship between immunity and inflammation in chronic inflammatory arthritis. Rheumatology (Oxford) 42: 716-731. doi: 10.1093/rheumatology/keg262
    • (2003) Rheumatology (Oxford , vol.42 , pp. 716-731
    • Cope, A.P.1
  • 28
    • 84870501644 scopus 로고    scopus 로고
    • The issue of comparators in economic evaluations of biologic response modifiers in rheumatoid arthritis
    • Tsao NW, Bansback NJ, Shojania K, Marra CA (2012) The issue of comparators in economic evaluations of biologic response modifiers in rheumatoid arthritis. Best Pract Res Clin Rheumatol 26: 659-676. doi: 10.1016/j.berh.2012.07.012
    • (2012) Best Pract Res Clin Rheumatol , vol.26 , pp. 659-676
    • Tsao, N.W.1    Bansback, N.J.2    Shojania, K.3    Marra, C.A.4
  • 29
    • 0142041982 scopus 로고    scopus 로고
    • Lasker clinical medical research award tnf defined as a therapeutic target for rheumatoid arthritis and other autoimmune diseases
    • Feldmann M, Maini RN (2003) Lasker Clinical Medical Research Award. TNF defined as a therapeutic target for rheumatoid arthritis and other autoimmune diseases. Nat Med 9: 1245-1250
    • (2003) Nat Med , vol.9 , pp. 1245-1250
    • Feldmann, M.1    Maini, R.N.2
  • 30
    • 0025827590 scopus 로고
    • A tumor necrosis factor (TNF) receptor-IgG heavy chain chimeric protein as a bivalent antagonist of TNF activity
    • Peppel K, Crawford D, Beutler B (1991) A tumor necrosis factor (TNF) receptor-IgG heavy chain chimeric protein as a bivalent antagonist of TNF activity. J Exp Med 174: 1483-1489. doi: 10.1084/jem.174. 6.1483
    • (1991) J Exp Med , vol.174 , pp. 1483-1489
    • Peppel, K.1    Crawford, D.2    Beutler, B.3
  • 31
    • 78751704593 scopus 로고    scopus 로고
    • Indirect comparisons of the efficacy of biological antirheumatic agents in rheumatoid arthritis in patients with an inadequate response to conventional disease-modifying antirheumatic drugs or to an anti-tumour necrosis factor agent: A meta-analysis
    • Salliot C, Finckh A, Katchamart W, Lu Y, Sun Y, et al. (2011) Indirect comparisons of the efficacy of biological antirheumatic agents in rheumatoid arthritis in patients with an inadequate response to conventional disease-modifying antirheumatic drugs or to an anti-tumour necrosis factor agent: a meta-analysis. Ann Rheum Dis 70: 266-271. doi: 10.1136/ard.2010.132134
    • (2011) Ann Rheum Dis , vol.70 , pp. 266-271
    • Salliot, C.1    Finckh, A.2    Katchamart, W.3    Lu, Y.4    Sun, Y.5
  • 32
    • 79951716374 scopus 로고    scopus 로고
    • Ten years with biologics: To whom do data on effectiveness and safety apply?
    • Simard JF, Arkema EV, Sundstrom A, Geborek P, Saxne T, et al. (2011) Ten years with biologics: to whom do data on effectiveness and safety apply? Rheumatology (Oxford) 50: 204-213. doi: 10.1093/rheumatology/keq326
    • (2011) Rheumatology (Oxford , vol.50 , pp. 204-213
    • Simard, J.F.1    Arkema, E.V.2    Sundstrom, A.3    Geborek, P.4    Saxne, T.5
  • 33
    • 33847239467 scopus 로고    scopus 로고
    • PI3K delta and PI3K gamma: Partners in crime in inflammation in rheumatoid arthritis and beyond?
    • Rommel C, Camps M, Ji H (2007) PI3K delta and PI3K gamma: partners in crime in inflammation in rheumatoid arthritis and beyond? Nat Rev Immunol 7: 191-201. doi: 10.1038/nri2036
    • (2007) Nat Rev Immunol , vol.7 , pp. 191-201
    • Rommel, C.1    Camps, M.2    Ji, H.3
  • 34
    • 0035953547 scopus 로고    scopus 로고
    • TREM-1 amplifies inflammation and is a crucial mediator of septic shock
    • Bouchon A, Facchetti F, Weigand MA, Colonna M (2001) TREM-1 amplifies inflammation and is a crucial mediator of septic shock. Nature 410: 1103-1107. doi: 10.1038/35074114
    • (2001) Nature , vol.410 , pp. 1103-1107
    • Bouchon, A.1    Facchetti, F.2    Weigand, M.A.3    Colonna, M.4
  • 35
    • 0346665750 scopus 로고    scopus 로고
    • A role for triggering receptor expressed on myeloid cells-1 in host defense during the early-induced and adaptive phases of the immune response
    • Bleharski JR, Kiessler V, Buonsanti C, Sieling PA, Stenger S, et al. (2003) A role for triggering receptor expressed on myeloid cells-1 in host defense during the early-induced and adaptive phases of the immune response. J Immunol 170: 3812-3818. doi: 10.4049/jimmunol.170.7.3812
    • (2003) J Immunol , vol.170 , pp. 3812-3818
    • Bleharski, J.R.1    Kiessler, V.2    Buonsanti, C.3    Sieling, P.A.4    Stenger, S.5
  • 36
    • 0034657890 scopus 로고    scopus 로고
    • Cutting edge: Inflammatory responses can be triggered by TREM-1, a novel receptor expressed on neutrophils and monocytes
    • Bouchon A, Dietrich J, Colonna M (2000) Cutting edge: inflammatory responses can be triggered by TREM-1, a novel receptor expressed on neutrophils and monocytes. J Immunol 164: 4991-4995. doi: 10.4049/jimmunol.164.10.4991
    • (2000) J Immunol , vol.164 , pp. 4991-4995
    • Bouchon, A.1    Dietrich, J.2    Colonna, M.3
  • 38
    • 10644237032 scopus 로고    scopus 로고
    • A soluble form of the triggering receptor expressed on myeloid cells-1 modulates the inflammatory response in murine sepsis
    • Gibot S, Kolopp-Sarda MN, Bene MC, Bollaert PE, Lozniewski A, et al. (2004) A soluble form of the triggering receptor expressed on myeloid cells-1 modulates the inflammatory response in murine sepsis. J Exp Med 200: 1419-1426. doi: 10.1084/jem.20040708
    • (2004) J Exp Med , vol.200 , pp. 1419-1426
    • Gibot, S.1    Kolopp-Sarda, M.N.2    Bene, M.C.3    Bollaert, P.E.4    Lozniewski, A.5
  • 39
    • 33749014675 scopus 로고    scopus 로고
    • Modulation of the triggering receptor expressed on myeloid cells-1 pathway during pneumonia in rats
    • Gibot S, Alauzet C, Massin F, Sennoune N, Faure GC, et al. (2006) Modulation of the triggering receptor expressed on myeloid cells-1 pathway during pneumonia in rats. J Infect Dis 194: 975-983. doi: 10. 1086/506950
    • (2006) J Infect Dis , vol.194 , pp. 975-983
    • Gibot, S.1    Alauzet, C.2    Massin, F.3    Sennoune, N.4    Faure, G.C.5
  • 40
    • 38449106594 scopus 로고    scopus 로고
    • Expression profile and function of triggering receptor expressed on myeloid cells-1 during melioidosis
    • Wiersinga WJ, Veer C, Wieland CW, Gibot S, Hooibrink B, et al. (2007) Expression profile and function of triggering receptor expressed on myeloid cells-1 during melioidosis. J Infect Dis 196: 1707-1716. doi: 10.1086/522141
    • (2007) J Infect Dis , vol.196 , pp. 1707-1716
    • Wiersinga, W.J.1    Veer, C.2    Wieland, C.W.3    Gibot, S.4    Hooibrink, B.5
  • 41
    • 84855189262 scopus 로고    scopus 로고
    • Soluble triggering receptor expressed on myeloid cells-1 as a new therapeutic molecule in rheumatoid arthritis
    • Kim TH, Choi SJ, Lee YH, Song GG, Ji JD (2012) Soluble triggering receptor expressed on myeloid cells-1 as a new therapeutic molecule in rheumatoid arthritis. Med Hypotheses 78: 270-272. doi: 10. 1016/j.mehy.2011.10.042
    • (2012) Med Hypotheses , vol.78 , pp. 270-272
    • Kim, T.H.1    Choi, S.J.2    Lee, Y.H.3    Song, G.G.4    Ji, J.D.5
  • 42
    • 33144467142 scopus 로고    scopus 로고
    • TREM2, a DAP12-associated receptor, regulates osteoclast differentiation and function
    • Humphrey MB, Daws MR, Spusta SC, Niemi EC, Torchia JA, et al. (2006) TREM2, a DAP12-associated receptor, regulates osteoclast differentiation and function. J Bone Miner Res 21: 237-245. doi: 10.1359/JBMR.051016
    • (2006) J Bone Miner Res , vol.21 , pp. 237-245
    • Humphrey, M.B.1    Daws, M.R.2    Spusta, S.C.3    Niemi, E.C.4    Torchia, J.A.5
  • 43
    • 0035887503 scopus 로고    scopus 로고
    • A DAP12-mediated pathway regulates expression of CC chemokine receptor 7 and maturation of human dendritic cells
    • Bouchon A, Hernandez-Munain C, Cella M, Colonna M (2001) A DAP12-mediated pathway regulates expression of CC chemokine receptor 7 and maturation of human dendritic cells. J Exp Med 194: 1111-1122. doi: 10.1084/jem.194.8.1111
    • (2001) J Exp Med , vol.194 , pp. 1111-1122
    • Bouchon, A.1    Hernandez-Munain, C.2    Cella, M.3    Colonna, M.4
  • 44
    • 0035086799 scopus 로고    scopus 로고
    • Cloning and characterization of a novel mouse myeloid DAP12-associated receptor family
    • Daws MR, Lanier LL, Seaman WE, Ryan JC (2001) Cloning and characterization of a novel mouse myeloid DAP12-associated receptor family. Eur J Immunol 31: 783-791. doi: 10.1002/1521-4141 (200103)31:3%3C783::AID-IMMU783%3E3.0.CO;2-U
    • (2001) Eur J Immunol , vol.31 , pp. 783-791
    • Daws, M.R.1    Lanier, L.L.2    Seaman, W.E.3    Ryan, J.C.4
  • 45
    • 33746875981 scopus 로고    scopus 로고
    • Cutting edge: Inhibition of TLR and FcR responses in macrophages by triggering receptor expressed on myeloid cells (TREM)-2 and DAP12
    • Hamerman JA, Jarjoura JR, Humphrey MB, Nakamura MC, Seaman WE, et al. (2006) Cutting edge: inhibition of TLR and FcR responses in macrophages by triggering receptor expressed on myeloid cells (TREM)-2 and DAP12. J Immunol 177: 2051-2055. doi: 10.4049/jimmunol.177.4.2051
    • (2006) J Immunol , vol.177 , pp. 2051-2055
    • Hamerman, J.A.1    Jarjoura, J.R.2    Humphrey, M.B.3    Nakamura, M.C.4    Seaman, W.E.5
  • 46
    • 0041419697 scopus 로고    scopus 로고
    • DAP12/TREM2 deficiency results in impaired osteoclast differentiation and osteoporotic features
    • Paloneva J, Mandelin J, Kiialainen A, Bohling T, Prudlo J, et al. (2003) DAP12/TREM2 deficiency results in impaired osteoclast differentiation and osteoporotic features. J Exp Med 198: 669-675. doi: 10. 1084/jem.20030027
    • (2003) J Exp Med , vol.198 , pp. 669-675
    • Paloneva, J.1    Mandelin, J.2    Kiialainen, A.3    Bohling, T.4    Prudlo, J.5
  • 47
    • 77949534181 scopus 로고    scopus 로고
    • Myeloid DAP12-associating lectin (MDL)-1 regulates synovial inflammation and bone erosion associated with autoimmune arthritis
    • Joyce-Shaikh B, Bigler ME, Chao CC, Murphy EE, Blumenschein WM, et al. (2010) Myeloid DAP12-associating lectin (MDL)-1 regulates synovial inflammation and bone erosion associated with autoimmune arthritis. J Exp Med 207: 579-589. doi: 10.1084/jem.20090516
    • (2010) J Exp Med , vol.207 , pp. 579-589
    • Joyce-Shaikh, B.1    Bigler, M.E.2    Chao, C.C.3    Murphy, E.E.4    Blumenschein, W.M.5
  • 48
    • 84907828314 scopus 로고    scopus 로고
    • A potential role of myeloid DAP12-associating lectin (MDL)-1 in the regulation of inflammation in rheumatoid arthritis patients
    • Chen DY, Yao L, Chen YM, Lin CC, Huang KC, et al. (2014) A potential role of myeloid DAP12-associating lectin (MDL)-1 in the regulation of inflammation in rheumatoid arthritis patients. PLoS One 9: e86105. doi: 10.1371/journal.pone.0086105
    • (2014) PLoS One , vol.9 , pp. e86105
    • Chen, D.Y.1    Yao, L.2    Chen, Y.M.3    Lin, C.C.4    Huang, K.C.5
  • 49
    • 80555134787 scopus 로고    scopus 로고
    • Activation of MDL-1 (CLEC5A) on immature myeloid cells triggers lethal shock in mice
    • Cheung R, Shen F, Phillips JH, McGeachy MJ, Cua DJ, et al. (2011) Activation of MDL-1 (CLEC5A) on immature myeloid cells triggers lethal shock in mice. J Clin Invest 121: 4446-4461. doi: 10.1172/JCI57682
    • (2011) J Clin Invest , vol.121 , pp. 4446-4461
    • Cheung, R.1    Shen, F.2    Phillips, J.H.3    McGeachy, M.J.4    Cua, D.J.5
  • 50
    • 84872065897 scopus 로고    scopus 로고
    • JAKs and STATs in immunity, immunodeficiency, and cancer
    • O'Shea JJ, Holland SM, Staudt LM (2013) JAKs and STATs in immunity, immunodeficiency, and cancer. N Engl J Med 368: 161-170. doi: 10.1056/NEJMra1202117
    • (2013) N Engl J Med , vol.368 , pp. 161-170
    • O'shea, J.J.1    Holland, S.M.2    Staudt, L.M.3
  • 51
    • 84879806081 scopus 로고    scopus 로고
    • Small molecules targeting JAKs-A new approach in the treatment of rheumatoid arthritis
    • Feist E, Burmester GR (2013) Small molecules targeting JAKs-a new approach in the treatment of rheumatoid arthritis. Rheumatology (Oxford) 52: 1352-1357. doi: 10.1093/rheumatology/kes417
    • (2013) Rheumatology (Oxford , vol.52 , pp. 1352-1357
    • Feist, E.1    Burmester, G.R.2
  • 52
    • 44449118619 scopus 로고    scopus 로고
    • Spleen tyrosine kinase: A novel target for therapeutic intervention of rheumatoid arthritis
    • Bajpai M, Chopra P, Dastidar SG, Ray A (2008) Spleen tyrosine kinase: a novel target for therapeutic intervention of rheumatoid arthritis. Expert Opin Investig Drugs 17: 641-659. doi: 10.1517/13543784. 17.5.641
    • (2008) Expert Opin Investig Drugs , vol.17 , pp. 641-659
    • Bajpai, M.1    Chopra, P.2    Dastidar, S.G.3    Ray, A.4
  • 53
    • 77953245981 scopus 로고    scopus 로고
    • A multitude of kinases-which are the best targets in treating rheumatoid arthritis?
    • Lindstrom TM, RobinsonWH (2010) A multitude of kinases-which are the best targets in treating rheumatoid arthritis? Rheum Dis Clin North Am 36: 367-383. doi: 10.1016/j.rdc.2010.02.005
    • (2010) Rheum Dis Clin North Am , vol.36 , pp. 367-383
    • Lindstrom, T.M.1    Robinson, W.H.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.