Proteolytic activation of the protease-activated receptor (PAR)-2 by the glycosylphosphatidylinositol-anchored serine protease testisin

Journal of Biological Chemistry

Volumn 290, Issue 6, 2015, Pages 3529-3541

  Driesbaugh, Kathryn H ^a,b   Buzza, Marguerite S ^a,b   Martin, Erik W ^a,b   Conway, Gregory D ^a,b   Kao, Joseph P Y ^a,c   Antalis, Toni M ^a,b,c  

^a Department of Physiology ^*  (United States)

^b Center for Vascular and Inflammatory Diseases   (United States)

^c UNIVERSITY OF MARYLAND SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

AMINO ACIDS; CELL MEMBRANES; CHEMICAL ACTIVATION; CYTOLOGY; GENE EXPRESSION; GLYCOSYLATION; LIGANDS;

BIOLOGICAL SUBSTRATES; G PROTEIN COUPLED RECEPTORS; GLYCOPHOSPHATIDYLINOSITOL; GLYCOSYLPHOSPHATIDYLINOSITOL; PROTEASE ACTIVATED RECEPTORS; PROTEOLYTIC ACTIVATION; SERUM RESPONSE ELEMENTS; TRYPSIN-LIKE SERINE PROTEASE;

ENZYME ACTIVITY;

CALCIUM ION; GLYCOSYLPHOSPHATIDYLINOSITOL ANCHORED PROTEASE TESTISIN; GLYCOSYLPHOSPHATIDYLINOSITOL ANCHORED PROTEIN; INTERLEUKIN 6; INTERLEUKIN 8; MESSENGER RNA; MITOGEN ACTIVATED PROTEIN KINASE 3; PROTEINASE ACTIVATED RECEPTOR 2; THROMBIN; TRYPSIN; UNCLASSIFIED DRUG; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; PRSS21 PROTEIN, MOUSE; SERINE PROTEINASE;

ARTICLE; CALCIUM CELL LEVEL; CALCIUM MOBILIZATION; CALCIUM TRANSPORT; CANCER CELL; CELL SURFACE; ENZYME ACTIVITY; GENE ACTIVITY; HUMAN; HUMAN CELL; OVARY CANCER; PROTEIN CLEAVAGE; PROTEIN DEPLETION; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN PHOSPHORYLATION; PROTEIN SECRETION; REPORTER GENE; CALCIUM SIGNALING; CELL MEMBRANE; CHEMISTRY; DNA RESPONSIVE ELEMENT; GENETICS; HEK293 CELL LINE; HELA CELL LINE; METABOLISM; PROTEIN DEGRADATION; SIGNAL TRANSDUCTION;

CALCIUM SIGNALING; CELL MEMBRANE; GPI-LINKED PROTEINS; HEK293 CELLS; HELA CELLS; HUMANS; INTERLEUKIN-6; INTERLEUKIN-8; MAP KINASE SIGNALING SYSTEM; NF-KAPPA B; PROTEOLYSIS; RECEPTOR, PAR-2; RESPONSE ELEMENTS; SERINE ENDOPEPTIDASES;

EID: 84922287405     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M114.628560     Document Type: Article

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