PAR2 triggers IL-8 release via MEK/ERK and PI3-kinase/Akt pathways in GI epithelial cells

Biochemical and Biophysical Research Communications

Volumn 377, Issue 2, 2008, Pages 622-626

  Tanaka, Yusuke ^a   Sekiguchi, Fumiko ^a   Hong, Hao ^a   Kawabata, Atsufumi ^a  

^a KINKI UNIVERSITY   (Japan)

Author keywords

ERK; Gastrointestinal epithelial cell; HCT 15 cell; Inflammation; Interleukin 8 (IL 8); MKN 45 cell; PI3 kinase; Proteinase activated receptor 2 (PAR2)

Indexed keywords

1,4 DIAMINO 1,4 BIS(2 AMINOPHENYLTHIO) 2,3 DICYANOBUTADIENE; 2 MORPHOLINO 8 PHENYLCHROMONE; INTERLEUKIN 8; MITOGEN ACTIVATED PROTEIN KINASE; MITOGEN ACTIVATED PROTEIN KINASE INHIBITOR; PHOSPHATIDYLINOSITOL 3 KINASE; PHOSPHATIDYLINOSITOL 3 KINASE INHIBITOR; PROTEIN KINASE B; PROTEINASE ACTIVATED RECEPTOR 2;

ARTICLE; CONTROLLED STUDY; CYTOKINE RELEASE; ENZYME PHOSPHORYLATION; GASTROINTESTINAL TRACT; HUMAN; HUMAN CELL; INFLAMMATION; INTESTINE EPITHELIUM CELL; PRIORITY JOURNAL; SIGNAL TRANSDUCTION; STOMACH EPITHELIUM;

1-PHOSPHATIDYLINOSITOL 3-KINASE; BUTADIENES; CELL LINE, TUMOR; CHROMONES; EPITHELIAL CELLS; EXTRACELLULAR SIGNAL-REGULATED MAP KINASES; GASTRIC MUCOSA; HUMANS; INTERLEUKIN-8; INTESTINAL MUCOSA; MAP KINASE KINASE KINASES; MORPHOLINES; NITRILES; PEPTIDES; PHOSPHORYLATION; PROTEIN KINASE INHIBITORS; PROTO-ONCOGENE PROTEINS C-AKT; RECEPTOR, PAR-2;

EID: 55549136709     PISSN: 0006291X     EISSN: 10902104     Source Type: Journal    
DOI: 10.1016/j.bbrc.2008.10.018     Document Type: Article

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