Regulated Shedding of PAR1 N-terminal Exodomain from Endothelial Cells

Journal of Biological Chemistry

Volumn 279, Issue 18, 2004, Pages 18592-18599

  Ludeman, Matthew J ^a   Zheng, Yao Wu ^a   Ishii, Kenji ^c   Coughlin, Shaun R ^a,b  

^a UNIVERSITY OF CALIFORNIA   (United States)

^b UNIVERSITY OF CALIFORNIA   (United States)

^c KYOTO UNIVERSITY GRADUATE SCHOOL OF MEDICINE   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

CELLS; ESTERS; PROTEINS; TISSUE;

CHIMERIC PROTEINS; ENDOTHELIAL CELLS;

BIOCHEMISTRY;

G PROTEIN COUPLED RECEPTOR; METALLOPROTEINASE; PHENANTHROLINE; PHORBOL ESTER; PROTEIN KINASE C; PROTEINASE ACTIVATED RECEPTOR 1; PROTEINASE INHIBITOR; THROMBIN; TUMOR NECROSIS FACTOR ALPHA CONVERTING ENZYME; TUMOR NECROSIS FACTOR ALPHA PROTEASE INHIBITOR 2; UNCLASSIFIED DRUG;

AMINO TERMINAL SEQUENCE; ANIMAL CELL; ARTICLE; CELL SURFACE; CHIMERA; CONTROLLED STUDY; ENDOTHELIUM CELL; ENZYME ACTIVATION; HUMAN; HUMAN CELL; NONHUMAN; PRIORITY JOURNAL; PROTEIN DEGRADATION; PROTEIN DOMAIN; PROTEIN EXPRESSION; PROTEIN SECRETION; SIGNAL TRANSDUCTION;

ALKALINE PHOSPHATASE; AMINO ACID SEQUENCE; ENDOTHELIUM, VASCULAR; ENZYME ACTIVATION; HUMANS; HYDROLYSIS; LIGANDS; METALLOPROTEASES; PROTEASE INHIBITORS; PROTEIN STRUCTURE, TERTIARY; RECEPTOR, PAR-1; RECOMBINANT FUSION PROTEINS; THROMBIN; UMBILICAL VEINS;

ANIMALIA;

EID: 2442592928     PISSN: 00219258     EISSN: None     Source Type: Journal    
DOI: 10.1074/jbc.M310836200     Document Type: Article

References (38)

1. Schlondorff, J., and Blobel, C. P. (1999) J. Cell Sci. 112, 3603-3617
2. Sunnarborg, S. W., Hinkle, C. L., Stevenson, M., Russell, W. E., Raska, C. S., Peschon, J. J., Castner, B. J., Gerhart, M. J., Paxton, R. J., Black, R. A., and Lee, D. C. (2002) J. Biol. Chem. 277, 12838-12845
3. Prenzel, N., Zwick, E., Daub, H., Leserer, M., Abraham, R., Wallasch, C., and Ullrich, A. (1999) Nature 402, 884-888
4. Peschon, J. J., Slack, J. L., Reddy, P., Stocking, K. L., Sunnarborg, S. W., Lee, D. C., Russell, W. E., Castner, B. J., Johnson, R. S., Fitzner, J. N., Boyce, R. W., Nelson, N., Kozlosky, C. J., Wolfson, M. F., Rauch, C. T., Cerretti, D. P., Paxton, R. J., March, C. J., and Black, R. A. (1998) Science 282, 1281-1284
5. Zhao, J., Chen, H., Peschon, J. J., Shi, W., Zhang, Y., Frank, S. J., and Warburton, D. (2001) Dev. Biol. 232, 204-218
6. Garton, K. J., Gough, P. J., Philalay, J., Wille, P. T., Blobel, C. P., Whitehead, R. H., Dempsey, P. J., and Raines, E. W. (2003) J. Biol. Chem. 23, 23
7. Gschwind, A., Hart, S., Fischer, O. M., and Ullrich, A. (2003) EMBO J. 22, 2411-2421
8. Tsou, C. L., Haskell, C. A., and Charo, I. F. (2001) J. Biol. Chem. 276, 44622-44626
9. Fitzgerald, M. L., Wang, Z., Park, P. W., Murphy, G., and Bernfield, M. (2000) J. Cell Biol. 148, 811-824
10. Marin, V., Montero-Julian, F., Gres, S., Bongrand, P., Farnarier, C., and Kaplanski, G. (2002) Eur. J. Immunol. 32, 2965-2970
11. Nath, D., Williamson, N. J., Jarvis, R., and Murphy, G. (2001) J. Cell Sci. 114, 1213-1220
12. Mullberg, J., Durie, F. H., Otten-Evans, C., Alderson, M. R., Rose-John, S., Cosman, D., Black, R. A., and Mohler, K. M. (1995) J. Immunol. 155, 5198-5205
13. Xu, J., Qu, D., Esmon, N. L., and Esmon, C. T. (2000) J. Biol. Chem. 275, 6038-6044
14. Vu, T. K., Hung, D. T., Wheaton, V. I., and Coughlin, S. R. (1991) Cell 64, 1057-1068
15. Hung, D. T., Vu, T. K., Wheaton, V. I., Ishii, K., and Coughlin, S. R. (1992) J. Clin. Investig. 89, 1350-1353
16. Ngaiza, J. R., and Jaffe, E. A. (1991) Biochem. Biophys. Res. Commun. 179, 1656-1661
17. Ueno, A., Murakami, K., Yamanouchi, K., Watanabe, M., and Kondo, T. (1996) Immunology 88, 76-81
18. Cunningham, M. A., Rondeau, E., Chen, X., Coughlin, S. R., Holdsworth, S. R., and Tipping, P. G. (2000) J. Exp. Med. 191, 455-462
19. Griffin, C. T., Srinivasan, Y., Zheng, Y. W., Huang, W., and Coughlin, S. R. (2001) Science 293, 1666-1670
20. Chen, J., Ishii, M., Wang, L., Ishii, K., Coughlin, S. R. (1994) J. Biol. Chem. 269
21. Ishii, K., Gerszten, R., Zheng, Y. W., Welsh, J. B., Turck, C. W., and Coughlin, S. R. (1995) J. Biol. Chem. 270, 16435-16440
22. Vouret-Craviari, V., Grall, D., Chambard, J. C., Rasmussen, U. B., Pouyssegur, J., Van, O., and Schilling, E. (1995) J. Biol. Chem. 270, 8367-8372
23. Molino, M., Blanchard, N., Belmonte, E., Tarver, A. P., Abrams, C., Hoxie, J. A., Cerletti, C., and Brass, L. F. (1995) J. Biol. Chem. 270, 11168-11175
24. Hammes, S. R., and Coughlin, S. R. (1999) Biochemistry 38, 2486-2493
25. Ishii, K., Hein, L., Kobilka, B., and Coughlin, S. R. (1993) J. Biol. Chem. 268, 9780-9786
26. Brass, L. F., Vassallo, R. J., Belmonte, E., Ahuja, M., Cichowski, K., and Hoxie, J. A. (1992) J. Biol. Chem. 267, 13795-13798
27. Chen, J., Ishii, M., Wang, L., Ishii, K., and Coughlin, S. R. (1994) J. Biol. Chem. 269, 16041-16045
28. Berger, J., Hauber, J., Hauber, R., Geiger, R., and Cullen, B. R. (1988) Gene (Amst.) 66, 1-10
29. Ishii, K., Chen, J., Ishii, M., Koch, W. J., Freedman, N. J., Lefkowitz, R. J., and Coughlin, S. R. (1994) J. Biol. Chem. 269, 1125-1130
30. Amour, A., Slocombe, P. M., Webster, A., Butler, M., Knight, C. G., Smith, B. J., Stephens, P. E., Shelley, C., Hutton, M., Knauper, V., Docherty, A. J., and Murphy, G. (1998) FEBS Lett. 435, 39-44
31. Borroto, A., Ruiz-Paz, S., de la Torre, T. V., Borrell-Pages, M., Merlos-Suarez, A., Pandiella, A., Blobel, C. P., Baselga, J., and Arribas, J. (2003) J. Biol. Chem. 278, 25933-25939
32. Weksler, B. B., Ley, C. W., and Jaffe, E. A. (1978) J. Clin. Investig. 62, 923-930
33. Woolkalis, M. J., DeMelfi, T. J., Blanchard, N., Hoxie, J. A., and Brass, L. F. (1995) J. Biol. Chem. 270, 9868-9875
34. O'Brien, P. J., Prevost, N., Molino, M., Hollinger, M. K., Woolkalis, M. J., Woulfe, D. S., and Brass, L. F. (2000) J. Biol. Chem. 275, 13502-13509
35. Imaizumi, T., Itaya, H., Fujita, K., Kudoh, D., Kudoh, S., Mori, K., Fujimoto, K., Matsumiya, T., Yoshida, H., and Satoh, K. (2000) Arterioscler. Thromb. Vasc. Biol. 20, 410-415
36. Boulday, G., Coupel, S., Coulon, F., Soulillou, J. P., and Charreau, B. (2001) Circ. Res. 88, 430-437
37. Yan, Y., Shirakabe, K., and Werb, Z. (2002) J. Cell Biol. 158, 221-226
38. Amour, A., Knight, C. G., Webster, A., Slocombe, P. M., Stephens, P. E., Knauper, V., Docherty, A. J., and Murphy, G. (2000) FEBS Lett. 473, 275-279