Supersaturation is a major driving force for protein aggregation in neurodegenerative diseases

Trends in Pharmacological Sciences

Volumn 36, Issue 2, 2015, Pages 72-77

  Ciryam, Prajwal ^a,b   Kundra, Rishika ^a   Morimoto, Richard I ^b   Dobson, Christopher M ^a   Vendruscolo, Michele ^a  

^a UNIVERSITY OF CAMBRIDGE   (United Kingdom)

^b NORTHWESTERN UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ALPHA SYNUCLEIN; HEAT SHOCK PROTEIN 90; HEXAFLUORO 2 PROPANOL; MELANIN; MELANOCYTE PROTEIN PMEL 17; TRIFLUOROETHANOL; PROTEIN; PROTEIN AGGREGATE; PROTEOME;

ALZHEIMER DISEASE; ARTICLE; CAENORHABDITIS ELEGANS; DEGENERATIVE DISEASE; GENETIC RISK; HUMAN; HUNTINGTON CHOREA; IN VITRO STUDY; IN VIVO STUDY; LEWY BODY; NONHUMAN; PARKINSON DISEASE; PATHOPHYSIOLOGY; PROTEIN AGGREGATION; PROTEIN DEGRADATION; PROTEIN EXPRESSION; PROTEIN HOMEOSTASIS; QUALITY CONTROL; SOLUBILITY; METABOLISM;

HUMANS; NEURODEGENERATIVE DISEASES; PROTEIN AGGREGATES; PROTEINS; PROTEOME;

EID: 84922246932     PISSN: 01656147     EISSN: 18733735     Source Type: Journal    
DOI: 10.1016/j.tips.2014.12.004     Document Type: Review

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