Correlation between mRNA expression levels and protein aggregation propensities in subcellular localisations

Molecular BioSystems

Volumn 5, Issue 12, 2009, Pages 1873-1876

  Tartaglia, Gian Gaetano ^a   Vendruscolo, Michele ^a  

^a UNIVERSITY OF CAMBRIDGE   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

MESSENGER RNA;

ANTIBODY SPECIFICITY; ARTICLE; BIOSYNTHESIS; CELL FRACTIONATION; GENE EXPRESSION; HUMAN; LIVER; METABOLISM; PHYSIOLOGY; PROTEIN MULTIMERIZATION; SOLUBILITY;

GENE EXPRESSION; HUMANS; LIVER; ORGAN SPECIFICITY; PROTEIN MULTIMERIZATION; RNA, MESSENGER; SOLUBILITY; SUBCELLULAR FRACTIONS;

EID: 72949113219     PISSN: 1742206X     EISSN: 17422051     Source Type: Journal    
DOI: 10.1039/b913099n     Document Type: Article

References (23)

1. G. G. Tartaglia S. Pechmann C. M. Dobson M. Vendruscolo Life on the edge: A link between gene expression levels and aggregation rates of human proteins Trends Biochem. Sci. 2007 32 204 206
2. M. A. DePristo D. M. Weinreich D. L. Hartl Missense meanderings in sequence space: A biophysical view of protein evolution Nat. Rev. Genet. 2005 6 678 687
3. M. Vendruscolo G. G. Tartaglia Towards quantitative predictions in cell biology using chemical properties of proteins Mol. BioSyst. 2008 4 1170 1175
4. G. G. Tartaglia S. Pechmann C. M. Dobson M. Vendruscolo A relationship between mRNA expression levels and protein solubility in E. Coli J. Mol. Biol. 2009 388 381 389
5. A. Drawid R. Jansen M. Gerstein Genome-wide analysis relating expression level with protein subcellular localization Trends Genet. 2000 16 426 430
6. G. G. Tartaglia A. Caflisch Computational analysis of the S. Cerevisiae proteome reveals the function and cellular localization of the least and most amyloidogenic proteins Proteins: Struct., Funct., Bioinf. 2007 68 273 278
7. E. Monsellier M. Ramazzotti N. Taddei F. Chiti Aggregation propensity of the human proteome PLoS Comput. Biol. 2008 4 e1000199
8. P. Lu C. Vogel R. Wang X. Yao E. M. Marcotte Absolute protein expression profiling estimates the relative contributions of transcriptional and translational regulation Nat. Biotechnol. 2007 25 117 124
9. G. G. Tartaglia A. P. Pawar S. Campioni C. M. Dobson F. Chiti M. Vendruscolo Prediction of aggregation-prone regions in structured proteins J. Mol. Biol. 2008 380 425 436
10. G. G. Tartaglia M. Vendruscolo The Zyggregator method for predicting protein aggregation propensities Chem. Soc. Rev. 2008 37 1395 1401
11. A. von Mikecz Xenobiotic-induced autoimmunity and protein aggregation diseases share a common subnuclear pathology Autoimmun. Rev. 2005 4 214 218
12. G. G. Tartaglia R. Pellarin A. Cavalli A. Caflisch Organism complexity anti-correlates with proteomic beta-aggregation propensity Protein Sci. 2005 14 2735 2740
13. A. I. Su T. Wiltshire S. Batalov H. Lapp K. A. Ching D. Block J. Zhang R. Soden M. Hayakawa G. Kreiman M. P. Cooke J. R. Walker J. B. Hogenesch A gene atlas of the mouse and human protein-encoding transcriptomes Proc. Natl. Acad. Sci. U. S. A. 2004 101 6062 6067
14. B. M. Bolstad R. A. Irizarry M. Astrand T. P. Speed A comparison of normalization methods for high density oligonucleotide array data based on variance and bias Bioinformatics 2003 19 185 193
15. A. P. Minton The influence of macromolecular crowding and macromolecular confinement on biochemical reactions in physiological media J. Biol. Chem. 2001 276 10577 10580
16. R. J. Ellis Macromolecular crowding: Obvious but underappreciated Trends Biochem. Sci. 2001 26 597 604
17. B. Alberts, A. Johnson, J. Lewis, M. Raff, K. Roberts and P. Walter, Molecular Biology of the Cell, Garland Science Publishing, New York, 2002
18. J. M. Sturgess F. A. Delaigle Morphometry of Golgi apparatus in developing liver J. Cell Biol. 1972 55 524 530
19. I. E. Scheffler, Mitochondria, Wiley & Sons, New York, 1999
20. P. Hozak P. R. Cook C. Schofer W. Mosgoller F. Wachtler Site of transcription of ribosomal-rna and intranucleolar structure in hela-cells J. Cell Sci. 1994 107 639 648
21. W. Kuhnel, Color Atlas of Cytology, Histology and Microscopic Anatomy, Georg Thieme Verlag, New York, 2003
22. A. Tinazli J. Piehler M. Beuttler R. Guckenberger R. Tampe Native protein nanolithography that can write, read and erase Nat. Nanotechnol. 2007 2 220 225
23. A. T. Dinh C. Pangarkar S. Mitragotri Understand discrete nanoscale transport Chem. Eng. Prog. 2008 104 62 68