메뉴 건너뛰기




Volumn 25, Issue 5, 2016, Pages 459-465

Retinal microglia in glaucoma

Author keywords

microglia targeted therapy; optic nerve crush; retina; retinal astrocytes; retinal ganglion cells; retinal microglia

Indexed keywords

DEXAMETHASONE; TRIAMCINOLONE;

EID: 84922246287     PISSN: 10570829     EISSN: 1536481X     Source Type: Journal    
DOI: 10.1097/IJG.0000000000000200     Document Type: Review
Times cited : (55)

References (100)
  • 1
    • 84879808415 scopus 로고    scopus 로고
    • The microglial system in the eye and brain in response to stimuli in vivo
    • Ellis-Behnke RG, Jonas RA, Jonas JB. The microglial system in the eye and brain in response to stimuli in vivo. J Glaucoma. 2013;22(suppl 5):S32-S35.
    • (2013) J Glaucoma. , vol.22 , pp. S32-S35
    • Ellis-Behnke, R.G.1    Jonas, R.A.2    Jonas, J.B.3
  • 2
    • 84881008812 scopus 로고    scopus 로고
    • Brain and retinal microglia in health and disease: An unrecognized target of the renin-Angiotensin system
    • McCarthy CA, Widdop RE, Deliyanti D, et al. Brain and retinal microglia in health and disease: an unrecognized target of the renin-Angiotensin system. Clin Exp Pharmacol Physiol. 2013;40:571-579.
    • (2013) Clin Exp Pharmacol Physiol. , vol.40 , pp. 571-579
    • McCarthy, C.A.1    Widdop, R.E.2    Deliyanti, D.3
  • 3
    • 58149141584 scopus 로고    scopus 로고
    • Neuroprotective and toxic changes in microglia in neurodegenerative disease
    • Sawada M. Neuroprotective and toxic changes in microglia in neurodegenerative disease. Parkinsonism Relat Disord. 2009; 15(suppl 1):S39-S41.
    • (2009) Parkinsonism Relat Disord. , vol.15 , pp. S39-S41
    • Sawada, M.1
  • 4
    • 0035400044 scopus 로고    scopus 로고
    • Microglia in neuroregeneration
    • Aldskogius H. Microglia in neuroregeneration. Microsc Res Tech. 2001;54:40-46.
    • (2001) Microsc Res Tech. , vol.54 , pp. 40-46
    • Aldskogius, H.1
  • 5
    • 84864388752 scopus 로고    scopus 로고
    • Retinal ganglion cell loss is accompanied by antibody depositions and increased levels of microglia after immunization with retinal antigens
    • Joachim SC, Gramlich OW, Laspas P, et al. Retinal ganglion cell loss is accompanied by antibody depositions and increased levels of microglia after immunization with retinal antigens. PLoS One. 2012;7:e40616.
    • (2012) PLoS One. , vol.7 , pp. e40616
    • Joachim, S.C.1    Gramlich, O.W.2    Laspas, P.3
  • 6
    • 79953188707 scopus 로고    scopus 로고
    • Retinal microglial activation and inflammation induced by amadoriglycated albumin in a rat model of diabetes
    • Ibrahim AS, El-Remessy AB, Matragoon S, et al. Retinal microglial activation and inflammation induced by amadoriglycated albumin in a rat model of diabetes. Diabetes. 2011;60:1122-1133.
    • (2011) Diabetes. , vol.60 , pp. 1122-1133
    • Ibrahim, A.S.1    El-Remessy, A.B.2    Matragoon, S.3
  • 7
    • 63249118590 scopus 로고    scopus 로고
    • Optic nerve infarction and post-ischemic inflammation in the rodent model of anterior ischemic optic neuropathy (rAION)
    • Zhang C, Guo Y, Miller NR, et al. Optic nerve infarction and post-ischemic inflammation in the rodent model of anterior ischemic optic neuropathy (rAION). Brain Res. 2009;1264: 67-75.
    • (2009) Brain Res. , vol.1264 , pp. 67-75
    • Zhang, C.1    Guo, Y.2    Miller, N.R.3
  • 8
    • 84889577792 scopus 로고    scopus 로고
    • Optic nerve inflammation and demyelination in a rodent model of nonarteritic anterior ischemic optic neuropathy
    • Slater BJ, Vilson FL, Guo Y, et al. Optic nerve inflammation and demyelination in a rodent model of nonarteritic anterior ischemic optic neuropathy. Invest Ophthalmol Vis Sci. 2013; 54:7952-7961.
    • (2013) Invest Ophthalmol Vis Sci. , vol.54 , pp. 7952-7961
    • Slater, B.J.1    Vilson, F.L.2    Guo, Y.3
  • 9
    • 0033372345 scopus 로고    scopus 로고
    • Brain cytokine network and novel characteristics of microglia
    • Sawada M. Brain cytokine network and novel characteristics of microglia. Nihon Shinkei Seishin Yakurigaku Zasshi. 1999; 19:151-154.
    • (1999) Nihon Shinkei Seishin Yakurigaku Zasshi. , vol.19 , pp. 151-154
    • Sawada, M.1
  • 10
    • 64549116740 scopus 로고    scopus 로고
    • Equal numbers of neuronal and nonneuronal cells make the human brain an isometrically scaled-up primate brain
    • Azevedo FA, Carvalho LR, Grinberg LT, et al. Equal numbers of neuronal and nonneuronal cells make the human brain an isometrically scaled-up primate brain. J Comp Neurol. 2009;513:532-541.
    • (2009) J Comp Neurol. , vol.513 , pp. 532-541
    • Azevedo, F.A.1    Carvalho, L.R.2    Grinberg, L.T.3
  • 11
    • 0025220976 scopus 로고
    • Heterogeneity in the distribution and morphology of microglia in the normal adult mouse brain
    • Lawson LJ, Perry VH, Dri P, et al. Heterogeneity in the distribution and morphology of microglia in the normal adult mouse brain. Neuroscience. 1990;39:151-170.
    • (1990) Neuroscience. , vol.39 , pp. 151-170
    • Lawson, L.J.1    Perry, V.H.2    Dri, P.3
  • 12
    • 33846571886 scopus 로고    scopus 로고
    • The origin and cell lineage of microglia: New concepts
    • Chan WY, Kohsaka S, Rezaie P. The origin and cell lineage of microglia: new concepts. Brain Res Rev. 2007;53:344-354.
    • (2007) Brain Res Rev. , vol.53 , pp. 344-354
    • Chan, W.Y.1    Kohsaka, S.2    Rezaie, P.3
  • 13
    • 71449114384 scopus 로고    scopus 로고
    • Macroglial cells of the teleost central nervous system: A survey of the main types
    • Cuoghi B, Mola L. Macroglial cells of the teleost central nervous system: a survey of the main types. Cell Tissue Res. 2009;338:319-332.
    • (2009) Cell Tissue Res. , vol.338 , pp. 319-332
    • Cuoghi, B.1    Mola, L.2
  • 15
    • 51449114026 scopus 로고    scopus 로고
    • Bone-marrow-derived microglia: Myth or reality
    • Soulet D, Rivest S. Bone-marrow-derived microglia: myth or reality. Curr Opin Pharmacol. 2008;8:508-518.
    • (2008) Curr Opin Pharmacol. , vol.8 , pp. 508-518
    • Soulet, D.1    Rivest, S.2
  • 16
    • 0037963473 scopus 로고    scopus 로고
    • Blood monocytes consist of two principal subsets with distinct migratory properties
    • Geissmann F, Jung S, Littman DR. Blood monocytes consist of two principal subsets with distinct migratory properties. Immunity. 2003;19:71-82.
    • (2003) Immunity. , vol.19 , pp. 71-82
    • Geissmann, F.1    Jung, S.2    Littman, D.R.3
  • 17
    • 36448955070 scopus 로고    scopus 로고
    • Microglia in the adult brain arise from Ly-6ChiCCR2+ monocytes only under defined host conditions
    • Mildner A, Schmidt H, NitscheM, et al. Microglia in the adult brain arise from Ly-6ChiCCR2+ monocytes only under defined host conditions. Nat Neurosci. 2007;10:1544-1553.
    • (2007) Nat Neurosci. , vol.10 , pp. 1544-1553
    • Mildner, A.1    Schmidt, H.2    Nitsche, M.3
  • 18
    • 84862815733 scopus 로고    scopus 로고
    • Para-inflammation-mediated retinal recruitment of bone marrow-derived myeloid cells following whole-body irradiation is CCL2 dependent
    • Chen M, Zhao J, Luo C, et al. Para-inflammation-mediated retinal recruitment of bone marrow-derived myeloid cells following whole-body irradiation is CCL2 dependent. Glia. 2012;60:833-842.
    • (2012) Glia. , vol.60 , pp. 833-842
    • Chen, M.1    Zhao, J.2    Luo, C.3
  • 19
    • 0032737272 scopus 로고    scopus 로고
    • Microglia derive from progenitors, originating from the yolk sac, and which proliferate in the brain
    • Alliot F, Godin I, Pessac B. Microglia derive from progenitors, originating from the yolk sac, and which proliferate in the brain. Brain Res Dev Brain Res. 1999;117:145-152.
    • (1999) Brain Res Dev Brain Res. , vol.117 , pp. 145-152
    • Alliot, F.1    Godin, I.2    Pessac, B.3
  • 20
    • 4644308783 scopus 로고    scopus 로고
    • Microglia: Phagocyte and glia cell
    • Vilhardt F. Microglia: phagocyte and glia cell. Int J Biochem Cell Biol. 2005;37:17-21.
    • (2005) Int J Biochem Cell Biol. , vol.37 , pp. 17-21
    • Vilhardt, F.1
  • 21
    • 0037942601 scopus 로고    scopus 로고
    • The blood-brain barrier and its role in immune privilege in the central nervous system
    • Pachter JS, de Vries HE, Fabry Z. The blood-brain barrier and its role in immune privilege in the central nervous system. J Neuropathol Exp Neurol. 2003;62:593-604.
    • (2003) J Neuropathol Exp Neurol. , vol.62 , pp. 593-604
    • Pachter, J.S.1    De Vries, H.E.2    Fabry, Z.3
  • 22
    • 84876784407 scopus 로고    scopus 로고
    • Innate immunity in the CNS: Redefining the relationship between the CNS and Its environment
    • Lampron A, Elali A, Rivest S. Innate immunity in the CNS: redefining the relationship between the CNS and Its environment. Neuron. 2013;78:214-232.
    • (2013) Neuron. , vol.78 , pp. 214-232
    • Lampron, A.1    Elali, A.2    Rivest, S.3
  • 23
    • 0031879209 scopus 로고    scopus 로고
    • Microglial cells prevent nitric oxide-induced neuronal apoptosis in vitro
    • Toku K, Tanaka J, Yano H, et al. Microglial cells prevent nitric oxide-induced neuronal apoptosis in vitro. J Neurosci Res. 1998;53:415-425.
    • (1998) J Neurosci Res. , vol.53 , pp. 415-425
    • Toku, K.1    Tanaka, J.2    Yano, H.3
  • 24
    • 0030970058 scopus 로고    scopus 로고
    • Role of macrophages/microglia in multiple sclerosis and experimental allergic encephalomyelitis
    • Benveniste EN. Role of macrophages/microglia in multiple sclerosis and experimental allergic encephalomyelitis. J Mol Med (Berl). 1997;75:165-173.
    • (1997) J Mol Med (Berl). , vol.75 , pp. 165-173
    • Benveniste, E.N.1
  • 25
    • 0035152836 scopus 로고    scopus 로고
    • Immune function of microglia
    • Aloisi F. Immune function of microglia. Glia. 2001;36: 165-179.
    • (2001) Glia. , vol.36 , pp. 165-179
    • Aloisi, F.1
  • 26
    • 84857406614 scopus 로고    scopus 로고
    • The spider effect: Morphological and orienting classification of microglia in response to stimuli in vivo
    • Jonas RA, Yuan TF, Liang YX, et al. The spider effect: morphological and orienting classification of microglia in response to stimuli in vivo. PLoS One. 2012;7:e30763.
    • (2012) PLoS One. , vol.7 , pp. e30763
    • Jonas, R.A.1    Yuan, T.F.2    Liang, Y.X.3
  • 27
    • 70350475289 scopus 로고    scopus 로고
    • Immune therapy with cultured microglia grafting into the injured spinal cord promoting the recovery of rat's hind limb motor function
    • Yu TB, Cheng YS, Zhao P, et al. Immune therapy with cultured microglia grafting into the injured spinal cord promoting the recovery of rat's hind limb motor function. Chin J Traumatol. 2009;12:291-295.
    • (2009) Chin J Traumatol. , vol.12 , pp. 291-295
    • Yu, T.B.1    Cheng, Y.S.2    Zhao, P.3
  • 28
    • 79952354608 scopus 로고    scopus 로고
    • Microglia-insights into immune system structure, function, and reactivity in the central nervous system
    • Wirenfeldt M, Babcock AA, Vinters HV. Microglia-insights into immune system structure, function, and reactivity in the central nervous system. Histol Histopathol. 2011;26: 519-530.
    • (2011) Histol Histopathol. , vol.26 , pp. 519-530
    • Wirenfeldt, M.1    Babcock, A.A.2    Vinters, H.V.3
  • 29
    • 73049110767 scopus 로고    scopus 로고
    • The multifaceted profile of activated microglia
    • Lynch MA. The multifaceted profile of activated microglia. Mol Neurobiol. 2009;40:139-156.
    • (2009) Mol Neurobiol. , vol.40 , pp. 139-156
    • Lynch, M.A.1
  • 30
    • 0036939328 scopus 로고    scopus 로고
    • Macrophages and microglia produce local trophic gradients that stimulate axonal sprouting toward but not beyond the wound edge
    • Batchelor PE, Porritt MJ, Martinello P, et al. Macrophages and microglia produce local trophic gradients that stimulate axonal sprouting toward but not beyond the wound edge. Mol Cell Neurosci. 2002;21:436-453.
    • (2002) Mol Cell Neurosci. , vol.21 , pp. 436-453
    • Batchelor, P.E.1    Porritt, M.J.2    Martinello, P.3
  • 31
    • 0041850026 scopus 로고    scopus 로고
    • Control of myeloid activity during retinal inflammation
    • Dick AD, Carter D, Robertson M, et al. Control of myeloid activity during retinal inflammation. J Leukoc Biol. 2003;74: 161-166.
    • (2003) J Leukoc Biol. , vol.74 , pp. 161-166
    • Dick, A.D.1    Carter, D.2    Robertson, M.3
  • 32
    • 84892174249 scopus 로고    scopus 로고
    • Translocator protein (18 kDa) (TSPO) is expressed in reactive retinal microglia and modulates microglial inflammation and phagocytosis
    • Karlstetter M, Nothdurfter C, Aslanidis A, et al. Translocator protein (18 kDa) (TSPO) is expressed in reactive retinal microglia and modulates microglial inflammation and phagocytosis. J Neuroinflammation. 2014;11:3.
    • (2014) J Neuroinflammation. , vol.11 , pp. 3
    • Karlstetter, M.1    Nothdurfter, C.2    Aslanidis, A.3
  • 33
    • 0035228049 scopus 로고    scopus 로고
    • Putting the brakes on innate immunity: A regulatory role for CD200
    • Nathan C, Muller WA. Putting the brakes on innate immunity: a regulatory role for CD200. Nat Immunol. 2001;2: 17-19.
    • (2001) Nat Immunol. , vol.2 , pp. 17-19
    • Nathan, C.1    Muller, W.A.2
  • 35
    • 0344407029 scopus 로고    scopus 로고
    • Microglial changes accompanying the promotion of retinal ganglion cell axonal regeneration into peripheral nerve grafts
    • Raibon E, Sauve Y, Carter DA, et al. Microglial changes accompanying the promotion of retinal ganglion cell axonal regeneration into peripheral nerve grafts. J Neurocytol. 2002; 31:57-71.
    • (2002) J Neurocytol. , vol.31 , pp. 57-71
    • Raibon, E.1    Sauve, Y.2    Carter, D.A.3
  • 36
    • 4444353422 scopus 로고    scopus 로고
    • Microglial responses in the avascular quail retina following transection of the optic nerve
    • Jeon GS, Kang TC, Park SW, et al. Microglial responses in the avascular quail retina following transection of the optic nerve. Brain Res. 2004;1023:15-23.
    • (2004) Brain Res. , vol.1023 , pp. 15-23
    • Jeon, G.S.1    Kang, T.C.2    Park, S.W.3
  • 37
    • 33748100942 scopus 로고    scopus 로고
    • Retinal microglial activation and chemotaxis by docosahexaenoic acid hydroperoxide
    • Saraswathy S, Wu G, Rao NA. Retinal microglial activation and chemotaxis by docosahexaenoic acid hydroperoxide. Invest Ophthalmol Vis Sci. 2006;47:3656-3663.
    • (2006) Invest Ophthalmol Vis Sci. , vol.47 , pp. 3656-3663
    • Saraswathy, S.1    Wu, G.2    Rao, N.A.3
  • 38
    • 77949345125 scopus 로고    scopus 로고
    • Microglial response to light-induced photoreceptor degeneration in the mouse retina
    • Santos AM, Martin-Oliva D, Ferrer-Martin RM, et al. Microglial response to light-induced photoreceptor degeneration in the mouse retina. J Comp Neurol. 2010;518: 477-492.
    • (2010) J Comp Neurol. , vol.518 , pp. 477-492
    • Santos, A.M.1    Martin-Oliva, D.2    Ferrer-Martin, R.M.3
  • 39
    • 84874663092 scopus 로고    scopus 로고
    • Roles of activated microglia in hypoxia induced neuroinflammation in the developing brain and the retina
    • Kaur C, Rathnasamy G, Ling EA. Roles of activated microglia in hypoxia induced neuroinflammation in the developing brain and the retina. J Neuroimmune Pharmacol. 2013;8:66-78.
    • (2013) J Neuroimmune Pharmacol. , vol.8 , pp. 66-78
    • Kaur, C.1    Rathnasamy, G.2    Ling, E.A.3
  • 40
    • 20344376926 scopus 로고    scopus 로고
    • Human retinal microglia express candidate receptors for HIV-1 infection
    • Pham VT, Wen L, McCluskey P, et al. Human retinal microglia express candidate receptors for HIV-1 infection. Br J Ophthalmol. 2005;89:753-757.
    • (2005) Br J Ophthalmol. , vol.89 , pp. 753-757
    • Pham, V.T.1    Wen, L.2    McCluskey, P.3
  • 41
    • 84887402319 scopus 로고    scopus 로고
    • Aging is not a disease: Distinguishing age-related macular degeneration from aging
    • Ardeljan D, Chan CC. Aging is not a disease: distinguishing age-related macular degeneration from aging. Prog Retin Eye Res. 2013;37:68-89.
    • (2013) Prog Retin Eye Res. , vol.37 , pp. 68-89
    • Ardeljan, D.1    Chan, C.C.2
  • 42
    • 0035135369 scopus 로고    scopus 로고
    • Activation of murine microglial cell lines by lipopolysaccharide and interferon-gamma causes NOmediated decreases in mitochondrial and cellular function
    • Moss DW, Bates TE. Activation of murine microglial cell lines by lipopolysaccharide and interferon-gamma causes NOmediated decreases in mitochondrial and cellular function. Eur J Neurosci. 2001;13:529-538.
    • (2001) Eur J Neurosci. , vol.13 , pp. 529-538
    • Moss, D.W.1    Bates, T.E.2
  • 43
    • 84855932333 scopus 로고    scopus 로고
    • Microglial activation and transcriptomic changes in the blue light-exposed mouse retina
    • Ebert S, Walczak Y, Reme C, et al. Microglial activation and transcriptomic changes in the blue light-exposed mouse retina. Adv Exp Med Biol. 2012;723:619-632.
    • (2012) Adv Exp Med Biol. , vol.723 , pp. 619-632
    • Ebert, S.1    Walczak, Y.2    Reme, C.3
  • 44
    • 79955823910 scopus 로고    scopus 로고
    • Retinal ganglion cell death is induced by microglia derived pro-inflammatory cytokines in the hypoxic neonatal retina
    • Sivakumar V, Foulds WS, Luu CD, et al. Retinal ganglion cell death is induced by microglia derived pro-inflammatory cytokines in the hypoxic neonatal retina. J Pathol. 2011;224: 245-260.
    • (2011) J Pathol. , vol.224 , pp. 245-260
    • Sivakumar, V.1    Foulds, W.S.2    Luu, C.D.3
  • 45
    • 36749051047 scopus 로고    scopus 로고
    • Chronic microglial activation and progressive dopaminergic neurotoxicity
    • Block ML, Hong JS. Chronic microglial activation and progressive dopaminergic neurotoxicity. Biochem Soc Trans. 2007;35:1127-1132.
    • (2007) Biochem Soc Trans. , vol.35 , pp. 1127-1132
    • Block, M.L.1    Hong, J.S.2
  • 46
    • 0020071220 scopus 로고
    • Identification of microglia cell of the rat retina by light and electron microscopy
    • Kohno T, Inomata H, Taniguchi Y. Identification of microglia cell of the rat retina by light and electron microscopy. Jpn J Ophthalmol. 1982;26:53-68.
    • (1982) Jpn J Ophthalmol. , vol.26 , pp. 53-68
    • Kohno, T.1    Inomata, H.2    Taniguchi, Y.3
  • 47
    • 84895985185 scopus 로고    scopus 로고
    • Comparative quantitative study of astrocytes and capillary distribution in optic nerve laminar regions
    • Balaratnasingam C, Kang MH, Yu P, et al. Comparative quantitative study of astrocytes and capillary distribution in optic nerve laminar regions. Exp Eye Res. 2014;121:11-22.
    • (2014) Exp Eye Res. , vol.121 , pp. 11-22
    • Balaratnasingam, C.1    Kang, M.H.2    Yu, P.3
  • 48
    • 0028911744 scopus 로고
    • Origin of microglia in the quail retina: Central-To-peripheral and vitrealto-scleral migration of microglial precursors during development
    • Navascues J, Moujahid A, Almendros A, et al. Origin of microglia in the quail retina: central-To-peripheral and vitrealto-scleral migration of microglial precursors during development. J Comp Neurol. 1995;354:209-228.
    • (1995) J Comp Neurol. , vol.354 , pp. 209-228
    • Navascues, J.1    Moujahid, A.2    Almendros, A.3
  • 49
    • 0036933302 scopus 로고    scopus 로고
    • Distribution, markers, and functions of retinal microglia
    • Chen L, Yang P, Kijlstra A. Distribution, markers, and functions of retinal microglia. Ocul Immunol Inflamm. 2002;10:27-39.
    • (2002) Ocul Immunol Inflamm. , vol.10 , pp. 27-39
    • Chen, L.1    Yang, P.2    Kijlstra, A.3
  • 50
    • 0029347050 scopus 로고
    • Human retinal microglia: Expression of immune markers and relationship to the glia limitans
    • Provis JM, Penfold PL, Edwards AJ, et al. Human retinal microglia: expression of immune markers and relationship to the glia limitans. Glia. 1995;14:243-256.
    • (1995) Glia. , vol.14 , pp. 243-256
    • Provis, J.M.1    Penfold, P.L.2    Edwards, A.J.3
  • 51
    • 0032809910 scopus 로고    scopus 로고
    • Microglia in the optic nerve head and the region of parapapillary chorioretinal atrophy in glaucoma
    • Neufeld AH. Microglia in the optic nerve head and the region of parapapillary chorioretinal atrophy in glaucoma. Arch Ophthalmol. 1999;117:1050-1056.
    • (1999) Arch Ophthalmol. , vol.117 , pp. 1050-1056
    • Neufeld, A.H.1
  • 52
    • 0032868404 scopus 로고    scopus 로고
    • Subretinal macrophages in the developing eye of eutherian mammals and marsupials
    • McMenamin PG. Subretinal macrophages in the developing eye of eutherian mammals and marsupials. Anat Embryol (Berl). 1999;200:551-558.
    • (1999) Anat Embryol (Berl). , vol.200 , pp. 551-558
    • McMenamin, P.G.1
  • 53
    • 0037215645 scopus 로고    scopus 로고
    • Role of microglia in inflammation-mediated neurodegenerative diseases: Mechanisms and strategies for therapeutic intervention
    • Liu B, Hong JS. Role of microglia in inflammation-mediated neurodegenerative diseases: mechanisms and strategies for therapeutic intervention. J Pharmacol Exp Ther. 2003;304:1-7.
    • (2003) J Pharmacol Exp Ther. , vol.304 , pp. 1-7
    • Liu, B.1    Hong, J.S.2
  • 54
    • 40449121975 scopus 로고    scopus 로고
    • Effects of aging on neuroprotective and neurotoxic properties of microglia in neurodegenerative diseases
    • Sawada M, Sawada H, Nagatsu T. Effects of aging on neuroprotective and neurotoxic properties of microglia in neurodegenerative diseases. Neurodegener Dis. 2008;5: 254-256.
    • (2008) Neurodegener Dis. , vol.5 , pp. 254-256
    • Sawada, M.1    Sawada, H.2    Nagatsu, T.3
  • 55
    • 84155162481 scopus 로고    scopus 로고
    • Role of pro-inflammatory cytokines released from microglia in neurodegenerative diseases
    • Smith JA, Das A, Ray SK, et al. Role of pro-inflammatory cytokines released from microglia in neurodegenerative diseases. Brain Res Bull. 2012;87:10-20.
    • (2012) Brain Res Bull. , vol.87 , pp. 10-20
    • Smith, J.A.1    Das, A.2    Ray, S.K.3
  • 56
    • 77957028140 scopus 로고    scopus 로고
    • Microglial activation and chronic neurodegeneration
    • Lull ME, Block ML. Microglial activation and chronic neurodegeneration. Neurotherapeutics. 2010;7:354-365.
    • (2010) Neurotherapeutics. , vol.7 , pp. 354-365
    • Lull, M.E.1    Block, M.L.2
  • 57
    • 84891827843 scopus 로고    scopus 로고
    • Progressive neurodegeneration after experimental brain trauma: Association with chronic microglial activation
    • Loane DJ, Kumar A, Stoica BA, et al. Progressive neurodegeneration after experimental brain trauma: association with chronic microglial activation. J Neuropathol Exp Neurol. 2014;73:14-29.
    • (2014) J Neuropathol Exp Neurol. , vol.73 , pp. 14-29
    • Loane, D.J.1    Kumar, A.2    Stoica, B.A.3
  • 58
    • 84908013034 scopus 로고    scopus 로고
    • Cellular responses following retinal injuries and therapeutic approaches for neurodegenerative diseases
    • Cuenca N, Fernandez-Sanchez L, Campello L, et al. Cellular responses following retinal injuries and therapeutic approaches for neurodegenerative diseases. Prog Retin Eye Res. 2014;43C:17-75.
    • (2014) Prog Retin Eye Res. , vol.43 C , pp. 17-75
    • Cuenca, N.1    Fernandez-Sanchez, L.2    Campello, L.3
  • 59
    • 84902531794 scopus 로고    scopus 로고
    • Retinal microglia are activated by systemic fungal infection
    • Maneu V, Noailles A, Megias J, et al. Retinal microglia are activated by systemic fungal infection. Invest Ophthalmol Vis Sci. 2014;55:3578-3585.
    • (2014) Invest Ophthalmol Vis Sci. , vol.55 , pp. 3578-3585
    • Maneu, V.1    Noailles, A.2    Megias, J.3
  • 60
    • 75949099155 scopus 로고    scopus 로고
    • Modulation of morphological changes of microglia and neuroprotection by monocyte chemoattractant protein-1 in experimental glaucoma
    • Chiu K, Yeung SC, So KF, et al. Modulation of morphological changes of microglia and neuroprotection by monocyte chemoattractant protein-1 in experimental glaucoma. Cell Mol Immunol. 2010;7:61-68.
    • (2010) Cell Mol Immunol. , vol.7 , pp. 61-68
    • Chiu, K.1    Yeung, S.C.2    So, K.F.3
  • 61
    • 78751489896 scopus 로고    scopus 로고
    • Early microglia activation in a mouse model of chronic glaucoma
    • Bosco A, Steele MR, Vetter ML. Early microglia activation in a mouse model of chronic glaucoma. J Comp Neurol. 2011; 519:599-620.
    • (2011) J Comp Neurol. , vol.519 , pp. 599-620
    • Bosco, A.1    Steele, M.R.2    Vetter, M.L.3
  • 62
    • 84860815301 scopus 로고    scopus 로고
    • IOP induces upregulation of GFAP and MHC-II and microglia reactivity in mice retina contralateral to experimental glaucoma
    • Gallego BI, Salazar JJ, de Hoz R, et al. IOP induces upregulation of GFAP and MHC-II and microglia reactivity in mice retina contralateral to experimental glaucoma. J Neuroinflammation. 2012;9:92.
    • (2012) J Neuroinflammation. , vol.9 , pp. 92
    • Gallego, B.I.1    Salazar, J.J.2    De Hoz, R.3
  • 63
    • 84865605323 scopus 로고    scopus 로고
    • Early reduction of microglia activation by irradiation in a model of chronic glaucoma
    • Bosco A, Crish SD, Steele MR, et al. Early reduction of microglia activation by irradiation in a model of chronic glaucoma. PLoS One. 2012;7:e43602.
    • (2012) PLoS One. , vol.7 , pp. e43602
    • Bosco, A.1    Crish, S.D.2    Steele, M.R.3
  • 64
    • 0036727499 scopus 로고    scopus 로고
    • Detection of early neuron degeneration and accompanying microglial responses in the retina of a rat model of glaucoma
    • Naskar R, Wissing M, Thanos S. Detection of early neuron degeneration and accompanying microglial responses in the retina of a rat model of glaucoma. Invest Ophthalmol Vis Sci. 2002;43:2962-2968.
    • (2002) Invest Ophthalmol Vis Sci. , vol.43 , pp. 2962-2968
    • Naskar, R.1    Wissing, M.2    Thanos, S.3
  • 65
    • 0024328421 scopus 로고
    • Parapapillary chorioretinal atrophy in normal and glaucoma eyes i Morphometric data
    • Jonas JB, Nguyen XN, Gusek GC, et al. Parapapillary chorioretinal atrophy in normal and glaucoma eyes. I. Morphometric data. Invest Ophthalmol Vis Sci. 1989;30: 908-918.
    • (1989) Invest Ophthalmol Vis Sci. , vol.30 , pp. 908-918
    • Jonas, J.B.1    Nguyen, X.N.2    Gusek, G.C.3
  • 66
    • 0024309095 scopus 로고
    • Parapapillary chorioretinal atrophy in normal and glaucoma eyes II Correlations
    • Jonas JB, Naumann GO. Parapapillary chorioretinal atrophy in normal and glaucoma eyes. II. Correlations. Invest Ophthalmol Vis Sci. 1989;30:919-926.
    • (1989) Invest Ophthalmol Vis Sci. , vol.30 , pp. 919-926
    • Jonas, J.B.1    Naumann, G.O.2
  • 67
    • 0027414171 scopus 로고
    • Parapapillary chorioretinal atrophy in normal-pressure glaucoma
    • Jonas JB, Xu L. Parapapillary chorioretinal atrophy in normal-pressure glaucoma. Am J Ophthalmol. 1993;115: 501-505.
    • (1993) Am J Ophthalmol. , vol.115 , pp. 501-505
    • Jonas, J.B.1    Xu, L.2
  • 68
    • 84874776157 scopus 로고    scopus 로고
    • Insulin-like growth factor 1 and 2 (IGF1, IGF2) expression in human microglia: Differential regulation by inflammatory mediators
    • Suh HS, Zhao ML, Derico L, et al. Insulin-like growth factor 1 and 2 (IGF1, IGF2) expression in human microglia: differential regulation by inflammatory mediators. J Neuroinflammation. 2013;10:37.
    • (2013) J Neuroinflammation. , vol.10 , pp. 37
    • Suh, H.S.1    Zhao, M.L.2    Derico, L.3
  • 69
    • 4744355622 scopus 로고    scopus 로고
    • CXCR3-dependent microglial recruitment is essential for dendrite loss after brain lesion
    • Rappert A, Bechmann I, Pivneva T, et al. CXCR3-dependent microglial recruitment is essential for dendrite loss after brain lesion. J Neurosci. 2004;24:8500-8509.
    • (2004) J Neurosci. , vol.24 , pp. 8500-8509
    • Rappert, A.1    Bechmann, I.2    Pivneva, T.3
  • 70
    • 17144403821 scopus 로고    scopus 로고
    • Retinoic acid inhibits expression of TNF-Alpha and iNOS in activated rat microglia
    • Dheen ST, Jun Y, Yan Z, et al. Retinoic acid inhibits expression of TNF-Alpha and iNOS in activated rat microglia. Glia. 2005;50:21-31.
    • (2005) Glia. , vol.50 , pp. 21-31
    • Dheen, S.T.1    Jun, Y.2    Yan, Z.3
  • 71
    • 78149489635 scopus 로고    scopus 로고
    • Glaucomatous tissue stress and the regulation of immune response through glial Toll-like receptor signaling
    • Luo C, Yang X, Kain AD, et al. Glaucomatous tissue stress and the regulation of immune response through glial Toll-like receptor signaling. Invest Ophthalmol Vis Sci. 2010;51: 5697-5707.
    • (2010) Invest Ophthalmol Vis Sci. , vol.51 , pp. 5697-5707
    • Luo, C.1    Yang, X.2    Kain, A.D.3
  • 72
    • 84918767482 scopus 로고    scopus 로고
    • Nanomedicine and its application in treatment of microglia-mediated neuroinflammation
    • Baby N, Patnala R, Ling EA, et al. Nanomedicine and its application in treatment of microglia-mediated neuroinflammation. Curr Med Chem. 2014;21:4215-4226.
    • (2014) Curr Med Chem. , vol.21 , pp. 4215-4226
    • Baby, N.1    Patnala, R.2    Ling, E.A.3
  • 73
    • 84859483480 scopus 로고    scopus 로고
    • Minocycline attenuates microglia activation and blocks the long-Term epileptogenic effects of early-life seizures
    • Abraham J, Fox PD, Condello C, et al. Minocycline attenuates microglia activation and blocks the long-Term epileptogenic effects of early-life seizures. Neurobiol Dis. 2012;46:425-430.
    • (2012) Neurobiol Dis. , vol.46 , pp. 425-430
    • Abraham, J.1    Fox, P.D.2    Condello, C.3
  • 74
    • 84872659111 scopus 로고    scopus 로고
    • Effects of minocycline on spatial learning, hippocampal neurogenesis and microglia in aged and adult mice
    • Kohman RA, Bhattacharya TK, Kilby C, et al. Effects of minocycline on spatial learning, hippocampal neurogenesis and microglia in aged and adult mice. Behav Brain Res. 2013;242:17-24.
    • (2013) Behav Brain Res. , vol.242 , pp. 17-24
    • Kohman, R.A.1    Bhattacharya, T.K.2    Kilby, C.3
  • 75
    • 84876722344 scopus 로고    scopus 로고
    • Minocycline inhibited the proapoptotic effect of microglia on neural progenitor cells and protected their neuronal differentiation in vitro
    • Liu X, Su H, Chu TH, et al. Minocycline inhibited the proapoptotic effect of microglia on neural progenitor cells and protected their neuronal differentiation in vitro. Neurosci Lett. 2013;542:30-36.
    • (2013) Neurosci Lett. , vol.542 , pp. 30-36
    • Liu, X.1    Su, H.2    Chu, T.H.3
  • 76
    • 1942454795 scopus 로고    scopus 로고
    • Minocycline delays photoreceptor death in the rds mouse through a microglia-independent mechanism
    • Hughes EH, Schlichtenbrede FC, Murphy CC, et al. Minocycline delays photoreceptor death in the rds mouse through a microglia-independent mechanism. Exp Eye Res. 2004;78: 1077-1084.
    • (2004) Exp Eye Res. , vol.78 , pp. 1077-1084
    • Hughes, E.H.1    Schlichtenbrede, F.C.2    Murphy, C.C.3
  • 77
    • 3242877090 scopus 로고    scopus 로고
    • Neuroprotection of photoreceptors by minocycline in light-induced retinal degeneration
    • Zhang C, Lei B, Lam TT, et al. Neuroprotection of photoreceptors by minocycline in light-induced retinal degeneration. Invest Ophthalmol Vis Sci. 2004;45:2753-2759.
    • (2004) Invest Ophthalmol Vis Sci. , vol.45 , pp. 2753-2759
    • Zhang, C.1    Lei, B.2    Lam, T.T.3
  • 78
    • 84868091439 scopus 로고    scopus 로고
    • Identification and characterization of triamcinolone acetonide, a microglial-Activation inhibitor
    • Hong J, Kim BK, Lim H, et al. Identification and characterization of triamcinolone acetonide, a microglial-Activation inhibitor. Immunopharmacol Immunotoxicol. 2012;34: 912-918.
    • (2012) Immunopharmacol Immunotoxicol. , vol.34 , pp. 912-918
    • Hong, J.1    Kim, B.K.2    Lim, H.3
  • 79
    • 84872077510 scopus 로고    scopus 로고
    • Effect of intravitreal triamcinolone acetonide on healing of retinal photocoagulation lesions
    • Nomoto H, Lavinsky D, Paulus YM, et al. Effect of intravitreal triamcinolone acetonide on healing of retinal photocoagulation lesions. Retina. 2013;33:63-70.
    • (2013) Retina. , vol.33 , pp. 63-70
    • Nomoto, H.1    Lavinsky, D.2    Paulus, Y.M.3
  • 80
    • 77951096645 scopus 로고    scopus 로고
    • Effect of intracameral triamcinolone acetonide on postoperative intraocular pressure after cataract surgery
    • Karalezli A, Borazan M, Kucukerdonmez C, et al. Effect of intracameral triamcinolone acetonide on postoperative intraocular pressure after cataract surgery. Eye (Lond). 2010;24:619-623.
    • (2010) Eye (Lond). , vol.24 , pp. 619-623
    • Karalezli, A.1    Borazan, M.2    Kucukerdonmez, C.3
  • 81
    • 84887417815 scopus 로고    scopus 로고
    • Efficacy and safety of intracameral triamcinolone acetonide to control postoperative inflammation after phacotrabeculectomy
    • Wang B, Dong N, Xu B, et al. Efficacy and safety of intracameral triamcinolone acetonide to control postoperative inflammation after phacotrabeculectomy. J Cataract Refract Surg. 2013;39:1691-1697.
    • (2013) J Cataract Refract Surg. , vol.39 , pp. 1691-1697
    • Wang, B.1    Dong, N.2    Xu, B.3
  • 82
    • 43549123926 scopus 로고    scopus 로고
    • Intracameral triamcinolone acetonide to control postoperative inflammation following cataract surgery with phacoemulsification
    • Karalezli A, Borazan M, Akova YA. Intracameral triamcinolone acetonide to control postoperative inflammation following cataract surgery with phacoemulsification. Acta Ophthalmol. 2008;86:183-187.
    • (2008) Acta Ophthalmol. , vol.86 , pp. 183-187
    • Karalezli, A.1    Borazan, M.2    Akova, Y.A.3
  • 83
    • 77957782858 scopus 로고    scopus 로고
    • Intracameral triamcinolone acetonide after pediatric cataract surgery
    • Cleary CA, Lanigan B, O'Keeffe M. Intracameral triamcinolone acetonide after pediatric cataract surgery. J Cataract Refract Surg. 2010;36:1676-1681.
    • (2010) J Cataract Refract Surg. , vol.36 , pp. 1676-1681
    • Cleary, C.A.1    Lanigan, B.2    O'Keeffe, M.3
  • 84
    • 84899972250 scopus 로고    scopus 로고
    • Results of intravitreal triamcinolone acetonide in patients with macular edema secondary to branch retinal vein occlusion
    • Demir M, Oba E, Guven D, et al. Results of intravitreal triamcinolone acetonide in patients with macular edema secondary to branch retinal vein occlusion. Int J Clin Pharm. 2014;36:438-442.
    • (2014) Int J Clin Pharm. , vol.36 , pp. 438-442
    • Demir, M.1    Oba, E.2    Guven, D.3
  • 85
    • 79952167196 scopus 로고    scopus 로고
    • Inhibitors of microglial neurotoxicity: Focus on natural products
    • Choi DK, Koppula S, Suk K. Inhibitors of microglial neurotoxicity: focus on natural products. Molecules. 2011;16:1021-1043.
    • (2011) Molecules. , vol.16 , pp. 1021-1043
    • Choi, D.K.1    Koppula, S.2    Suk, K.3
  • 86
    • 79956260639 scopus 로고    scopus 로고
    • Neuroprotection of Scutellarin is mediated by inhibition of microglial inflammatory activation
    • Wang S, Wang H, Guo H, et al. Neuroprotection of Scutellarin is mediated by inhibition of microglial inflammatory activation. Neuroscience. 2011;185:150-160.
    • (2011) Neuroscience. , vol.185 , pp. 150-160
    • Wang, S.1    Wang, H.2    Guo, H.3
  • 87
    • 84883176164 scopus 로고    scopus 로고
    • Brazilian green propolis suppresses the hypoxia-induced neuroinflammatory responses by inhibiting NF-kappaB activation in microglia
    • Wu Z, Zhu A, Takayama F, et al. Brazilian green propolis suppresses the hypoxia-induced neuroinflammatory responses by inhibiting NF-kappaB activation in microglia. Oxid Med Cell Longev. 2013;2013:906726.
    • (2013) Oxid Med Cell Longev. , vol.2013 , pp. 906726
    • Wu, Z.1    Zhu, A.2    Takayama, F.3
  • 88
    • 77951880056 scopus 로고    scopus 로고
    • Icariin attenuates lipopolysaccharide-induced microglial activation and resultant death of neurons by inhibiting TAK1/IKK/NF-kappaB and JNK/p38 MAPK pathways
    • Zeng KW, Fu H, Liu GX, et al. Icariin attenuates lipopolysaccharide-induced microglial activation and resultant death of neurons by inhibiting TAK1/IKK/NF-kappaB and JNK/p38 MAPK pathways. Int Immunopharmacol. 2010; 10:668-678.
    • (2010) Int Immunopharmacol. , vol.10 , pp. 668-678
    • Zeng, K.W.1    Fu, H.2    Liu, G.X.3
  • 89
    • 30644472503 scopus 로고    scopus 로고
    • Simplified extraction of ginsenosides from American ginseng (Panax quinquefolius L) for high-performance liquid chromatography-ultraviolet analysis
    • Corbit RM, Ferreira JF, Ebbs SD, et al. Simplified extraction of ginsenosides from American ginseng (Panax quinquefolius L) for high-performance liquid chromatography-ultraviolet analysis. J Agric Food Chem. 2005;53:9867-9873.
    • (2005) J Agric Food Chem. , vol.53 , pp. 9867-9873
    • Corbit, R.M.1    Ferreira, J.F.2    Ebbs, S.D.3
  • 90
    • 84881177499 scopus 로고    scopus 로고
    • Curcumin protects microglia and primary rat cortical neurons against HIV-1 gp120-mediated inflammation and apoptosis
    • Guo L, Xing Y, Pan R, et al. Curcumin protects microglia and primary rat cortical neurons against HIV-1 gp120-mediated inflammation and apoptosis. PLoS One. 2013;8: e70565.
    • (2013) PLoS One. , vol.8 , pp. e70565
    • Guo, L.1    Xing, Y.2    Pan, R.3
  • 91
    • 0035669598 scopus 로고    scopus 로고
    • Ginger: An ethnomedical, chemical and pharmacological review
    • Afzal M, Al-Hadidi D, Menon M, et al. Ginger: an ethnomedical, chemical and pharmacological review. Drug Metabol Drug Interact. 2001;18:159-190.
    • (2001) Drug Metabol Drug Interact. , vol.18 , pp. 159-190
    • Afzal, M.1    Al-Hadidi, D.2    Menon, M.3
  • 92
    • 84885365409 scopus 로고    scopus 로고
    • Improved retinal ganglion cell survival through retinal microglia suppression by a Chinese herb extract, triptolide, in the DBA/2 J mouse model of glaucoma
    • Yang F, Wu L, Guo X, et al. Improved retinal ganglion cell survival through retinal microglia suppression by a Chinese herb extract, triptolide, in the DBA/2 J mouse model of glaucoma. Ocul Immunol Inflamm. 2013;21:378-389.
    • (2013) Ocul Immunol Inflamm. , vol.21 , pp. 378-389
    • Yang, F.1    Wu, L.2    Guo, X.3
  • 93
    • 84912026274 scopus 로고    scopus 로고
    • Neuroprotective effect of curcumin against oxidative damage in BV-2 microglia and high intraocular pressure animal model
    • PubMed ID 24963995
    • Yue YK, Mo B, Zhao J, et al. Neuroprotective effect of curcumin against oxidative damage in BV-2 microglia and high intraocular pressure animal model. J Ocul Pharmacol Ther. 2014;PubMed ID:24963995.
    • (2014) J Ocul Pharmacol Ther.
    • Yue, Y.K.1    Mo, B.2    Zhao, J.3
  • 94
    • 84888380685 scopus 로고    scopus 로고
    • Activation of microglia induces symptoms of Parkinson's disease in wild-Type, but not in IL-1 knockout mice
    • Tanaka S, Ishii A, Ohtaki H, et al. Activation of microglia induces symptoms of Parkinson's disease in wild-Type, but not in IL-1 knockout mice. J Neuroinflammation. 2013;10:143.
    • (2013) J Neuroinflammation. , vol.10 , pp. 143
    • Tanaka, S.1    Ishii, A.2    Ohtaki, H.3
  • 95
    • 0033781980 scopus 로고    scopus 로고
    • Tumor necrosis factor-Alpha: A potentially neurodestructive cytokine produced by glia in the human glaucomatous optic nerve head
    • Yuan L, Neufeld AH. Tumor necrosis factor-Alpha: a potentially neurodestructive cytokine produced by glia in the human glaucomatous optic nerve head. Glia. 2000;3 2:42-50.
    • (2000) Glia. , vol.3 , Issue.2 , pp. 42-50
    • Yuan, L.1    Neufeld, A.H.2
  • 96
    • 84863625033 scopus 로고    scopus 로고
    • Etanercept, a widely used inhibitor of tumor necrosis factor-Alpha (TNF-Alpha), prevents retinal ganglion cell loss in a rat model of glaucoma
    • Roh M, Zhang Y, Murakami Y, et al. Etanercept, a widely used inhibitor of tumor necrosis factor-Alpha (TNF-Alpha), prevents retinal ganglion cell loss in a rat model of glaucoma. PLoS One. 2012;7:e40065.
    • (2012) PLoS One. , vol.7 , pp. e40065
    • Roh, M.1    Zhang, Y.2    Murakami, Y.3
  • 97
    • 84865282578 scopus 로고    scopus 로고
    • CD137 ligand activated microglia induces oligodendrocyte apoptosis via reactive oxygen species
    • Yeo YA, Martinez GJM, Croxford JL, et al. CD137 ligand activated microglia induces oligodendrocyte apoptosis via reactive oxygen species. J Neuroinflammation. 2012;9:173.
    • (2012) J Neuroinflammation. , vol.9 , pp. 173
    • Yeo, Y.A.1    Martinez, G.J.M.2    Croxford, J.L.3
  • 98
    • 36348955676 scopus 로고    scopus 로고
    • Toll-like receptor 3 is a potent negative regulator of axonal growth in mammals
    • Cameron JS, Alexopoulou L, Sloane JA, et al. Toll-like receptor 3 is a potent negative regulator of axonal growth in mammals. J Neurosci. 2007;27:13033-13041.
    • (2007) J Neurosci. , vol.27 , pp. 13033-13041
    • Cameron, J.S.1    Alexopoulou, L.2    Sloane, J.A.3
  • 99
    • 84862822312 scopus 로고    scopus 로고
    • Microglial TIR-domaincontaining adapter-inducing interferon-beta (TRIF) deficiency promotes retinal ganglion cell survival and axon regeneration via nuclear factor-kappaB
    • Lin S, Liang Y, Zhang J, et al. Microglial TIR-domaincontaining adapter-inducing interferon-beta (TRIF) deficiency promotes retinal ganglion cell survival and axon regeneration via nuclear factor-kappaB. J Neuroinflammation. 2012;9:39.
    • (2012) J Neuroinflammation. , vol.9 , pp. 39
    • Lin, S.1    Liang, Y.2    Zhang, J.3
  • 100
    • 67649838794 scopus 로고    scopus 로고
    • Long-Term accumulation of microglia with proneurogenic phenotype concomitant with persistent neurogenesis in adult subventricular zone after stroke
    • Thored P, Heldmann U, Gomes-Leal W, et al. Long-Term accumulation of microglia with proneurogenic phenotype concomitant with persistent neurogenesis in adult subventricular zone after stroke. Glia. 2009;57:835-849.
    • (2009) Glia. , vol.57 , pp. 835-849
    • Thored, P.1    Heldmann, U.2    Gomes-Leal, W.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.