-
1
-
-
56749169457
-
Lessons from multiple sclerosis: models, concepts, observations
-
Wekerle H. Lessons from multiple sclerosis: models, concepts, observations. Ann Rheum Dis 2008, Suppl 3:iii56-iii60.
-
(2008)
Ann Rheum Dis
, vol.Suppl 3
-
-
Wekerle, H.1
-
2
-
-
79959476848
-
Critical appraisal of animal models of multiple sclerosis
-
10.1177/1352458511398885, 21372117
-
Baker D, Gerritsen W, Rundle J, Amor S. Critical appraisal of animal models of multiple sclerosis. Mult Scler 2011, 17:647-657. 10.1177/1352458511398885, 21372117.
-
(2011)
Mult Scler
, vol.17
, pp. 647-657
-
-
Baker, D.1
Gerritsen, W.2
Rundle, J.3
Amor, S.4
-
3
-
-
77953715389
-
4-1BB as a therapeutic target for human disease
-
10.1007/978-0-387-89520-8_8, 19760070
-
Lee SW, Croft M. 4-1BB as a therapeutic target for human disease. Adv Exp Med Biol 2009, 647:120-129. 10.1007/978-0-387-89520-8_8, 19760070.
-
(2009)
Adv Exp Med Biol
, vol.647
, pp. 120-129
-
-
Lee, S.W.1
Croft, M.2
-
4
-
-
65349153714
-
Immune regulation by 4-1BB and 4-1BBL: complexities and challenges
-
10.1111/j.1600-065X.2009.00765.x, 19426223
-
Wang C, Lin GH, McPherson AJ, Watts TH. Immune regulation by 4-1BB and 4-1BBL: complexities and challenges. Immunol Rev 2009, 229:192-215. 10.1111/j.1600-065X.2009.00765.x, 19426223.
-
(2009)
Immunol Rev
, vol.229
, pp. 192-215
-
-
Wang, C.1
Lin, G.H.2
McPherson, A.J.3
Watts, T.H.4
-
5
-
-
77952319813
-
CD137, implications in immunity and potential for therapy
-
Thum E, Shao Z, Schwarz H. CD137, implications in immunity and potential for therapy. Front Biosci 2009, S1:336-351.
-
(2009)
Front Biosci
, vol.S1
, pp. 336-351
-
-
Thum, E.1
Shao, Z.2
Schwarz, H.3
-
6
-
-
30444442143
-
Renewed interest in cancer immunotherapy with the tumor necrosis factor superfamily molecules
-
10.1007/s00262-005-0081-y, 16187084
-
Tamada K, Chen L. Renewed interest in cancer immunotherapy with the tumor necrosis factor superfamily molecules. Cancer Immunol Immunother 2006, 55:355-362. 10.1007/s00262-005-0081-y, 16187084.
-
(2006)
Cancer Immunol Immunother
, vol.55
, pp. 355-362
-
-
Tamada, K.1
Chen, L.2
-
7
-
-
4344694114
-
Ligands working as receptors: reverse signaling by members of the TNF superfamily enhance the plasticity of the immune system
-
10.1016/j.cytogfr.2004.03.011, 15450251
-
Eissner G, Kolch W, Scheurich P. Ligands working as receptors: reverse signaling by members of the TNF superfamily enhance the plasticity of the immune system. Cytokine Growth Factor Rev 2004, 15:353-366. 10.1016/j.cytogfr.2004.03.011, 15450251.
-
(2004)
Cytokine Growth Factor Rev
, vol.15
, pp. 353-366
-
-
Eissner, G.1
Kolch, W.2
Scheurich, P.3
-
8
-
-
78650769051
-
CD137 ligand, a member of the tumor necrosis factor family, regulates immune responses via reverse signal transduction
-
10.1189/jlb.0510315, 20643812
-
Shao Z, Schwarz H. CD137 ligand, a member of the tumor necrosis factor family, regulates immune responses via reverse signal transduction. J Leukoc Biol 2011, 89:21-29. 10.1189/jlb.0510315, 20643812.
-
(2011)
J Leukoc Biol
, vol.89
, pp. 21-29
-
-
Shao, Z.1
Schwarz, H.2
-
9
-
-
0032032236
-
CD137 (ILA/4-1BB), a member of the TNF receptor family, induces monocyte activation via bidirectional signaling
-
Langstein J, Michel J, Fritsche J, Kreutz M, Andreesen R, Schwarz H. CD137 (ILA/4-1BB), a member of the TNF receptor family, induces monocyte activation via bidirectional signaling. J Immunol 1998, 160:2488-2494.
-
(1998)
J Immunol
, vol.160
, pp. 2488-2494
-
-
Langstein, J.1
Michel, J.2
Fritsche, J.3
Kreutz, M.4
Andreesen, R.5
Schwarz, H.6
-
10
-
-
0034709589
-
Comparative analysis of CD137 and LPS effects on monocyte activation, survival, and proliferation
-
10.1006/bbrc.2000.2889, 10873573
-
Langstein J, Becke FM, Sollner L, Krause G, Brockhoff G, Kreutz M, Andreesen R, Schwarz H. Comparative analysis of CD137 and LPS effects on monocyte activation, survival, and proliferation. Biochem Biophys Res Commun 2000, 273:117-122. 10.1006/bbrc.2000.2889, 10873573.
-
(2000)
Biochem Biophys Res Commun
, vol.273
, pp. 117-122
-
-
Langstein, J.1
Becke, F.M.2
Sollner, L.3
Krause, G.4
Brockhoff, G.5
Kreutz, M.6
Andreesen, R.7
Schwarz, H.8
-
11
-
-
0033063934
-
Identification of CD137 as a potent monocyte survival factor
-
Langstein J, Schwarz H. Identification of CD137 as a potent monocyte survival factor. J Leukoc Biol 1999, 65:829-833.
-
(1999)
J Leukoc Biol
, vol.65
, pp. 829-833
-
-
Langstein, J.1
Schwarz, H.2
-
12
-
-
0033229705
-
CD137 induces proliferation and endomitosis in monocytes
-
Langstein J, Michel J, Schwarz H. CD137 induces proliferation and endomitosis in monocytes. Blood 1999, 94:3161-3168.
-
(1999)
Blood
, vol.94
, pp. 3161-3168
-
-
Langstein, J.1
Michel, J.2
Schwarz, H.3
-
13
-
-
33846784977
-
CD137 is expressed on blood vessel walls at sites of inflammation and enhances monocyte migratory activity
-
10.1096/fj.05-4739com, 17167064
-
Drenkard D, Becke FM, Langstein J, Spruss T, Kunz-Schughart LA, Tan TE, Lim YC, Schwarz H. CD137 is expressed on blood vessel walls at sites of inflammation and enhances monocyte migratory activity. FASEB J 2007, 21:456-463. 10.1096/fj.05-4739com, 17167064.
-
(2007)
FASEB J
, vol.21
, pp. 456-463
-
-
Drenkard, D.1
Becke, F.M.2
Langstein, J.3
Spruss, T.4
Kunz-Schughart, L.A.5
Tan, T.E.6
Lim, Y.C.7
Schwarz, H.8
-
14
-
-
44849090095
-
CD137 ligand reverse signaling has multiple functions in human dendritic cells during an adaptive immune response
-
10.1002/eji.200737800, 18395851
-
Lippert U, Zachmann K, Ferrari DM, Schwarz H, Brunner E, Latif AH, Neumann C, Soruri A. CD137 ligand reverse signaling has multiple functions in human dendritic cells during an adaptive immune response. Eur J Immunol 2008, 38:1024-1032. 10.1002/eji.200737800, 18395851.
-
(2008)
Eur J Immunol
, vol.38
, pp. 1024-1032
-
-
Lippert, U.1
Zachmann, K.2
Ferrari, D.M.3
Schwarz, H.4
Brunner, E.5
Latif, A.H.6
Neumann, C.7
Soruri, A.8
-
15
-
-
70349506614
-
A novel approach to induce human DCs from monocytes by triggering 4-1BBL reverse signaling
-
10.1093/intimm/dxp077, 19684160
-
Ju S, Ju S, Ge Y, Qiu H, Lu B, Qiu Y, Fu J, Liu G, Wang Q, Hu Y, Shu Y, Zhang X. A novel approach to induce human DCs from monocytes by triggering 4-1BBL reverse signaling. Int Immunol 2009, 21:1135-1144. 10.1093/intimm/dxp077, 19684160.
-
(2009)
Int Immunol
, vol.21
, pp. 1135-1144
-
-
Ju, S.1
Ju, S.2
Ge, Y.3
Qiu, H.4
Lu, B.5
Qiu, Y.6
Fu, J.7
Liu, G.8
Wang, Q.9
Hu, Y.10
Shu, Y.11
Zhang, X.12
-
16
-
-
77954106919
-
CD137 ligand signaling induces human monocyte to dendritic cell differentiation
-
10.1002/eji.200940105, 20432236
-
Kwajah MMS, Schwarz H. CD137 ligand signaling induces human monocyte to dendritic cell differentiation. Eur J Immunol 2010, 40:1938-49. 10.1002/eji.200940105, 20432236.
-
(2010)
Eur J Immunol
, vol.40
, pp. 1938-1949
-
-
Kwajah, M.M.S.1
Schwarz, H.2
-
17
-
-
55049109182
-
Induction of proliferation and monocytic differentiation of human CD34+ cells by CD137 ligand signaling
-
10.1634/stemcells.2008-0158, 18566330
-
Jiang D, Yue PS, Drenkard D, Schwarz H. Induction of proliferation and monocytic differentiation of human CD34+ cells by CD137 ligand signaling. Stem Cells 2008, 26:2372-2381. 10.1634/stemcells.2008-0158, 18566330.
-
(2008)
Stem Cells
, vol.26
, pp. 2372-2381
-
-
Jiang, D.1
Yue, P.S.2
Drenkard, D.3
Schwarz, H.4
-
18
-
-
56149122030
-
CD137 induces proliferation of murine hematopoietic progenitor cells and differentiation to macrophages
-
Jiang D, Chen Y, Schwarz H. CD137 induces proliferation of murine hematopoietic progenitor cells and differentiation to macrophages. J Immunol 2008, 181:3923-3932.
-
(2008)
J Immunol
, vol.181
, pp. 3923-3932
-
-
Jiang, D.1
Chen, Y.2
Schwarz, H.3
-
19
-
-
78650233802
-
Microglia in the CNS: immigrants from another world
-
10.1002/glia.21104, 21125659
-
Prinz M, Mildner A. Microglia in the CNS: immigrants from another world. GLIA 2011, 59:177-187. 10.1002/glia.21104, 21125659.
-
(2011)
GLIA
, vol.59
, pp. 177-187
-
-
Prinz, M.1
Mildner, A.2
-
20
-
-
42749094922
-
From bone marrow to microglia: barriers and avenues
-
10.1016/j.it.2008.01.010, 18396103
-
Davoust N, Vuaillat C, Androdias G, Nataf S. From bone marrow to microglia: barriers and avenues. Trends Immunol 2008, 29:227-234. 10.1016/j.it.2008.01.010, 18396103.
-
(2008)
Trends Immunol
, vol.29
, pp. 227-234
-
-
Davoust, N.1
Vuaillat, C.2
Androdias, G.3
Nataf, S.4
-
21
-
-
34248392684
-
Microglial activation and its implications in the brain diseases
-
10.2174/092986707780597961, 17504139
-
Dheen ST, Kaur C, Ling EA. Microglial activation and its implications in the brain diseases. Curr Med Chem 2007, 14:1189-1197. 10.2174/092986707780597961, 17504139.
-
(2007)
Curr Med Chem
, vol.14
, pp. 1189-1197
-
-
Dheen, S.T.1
Kaur, C.2
Ling, E.A.3
-
22
-
-
34548563114
-
Activated microglia in primary MS lesions: defenders or aggressors?
-
Gay F. Activated microglia in primary MS lesions: defenders or aggressors?. Int MS J 2007, 14:78-83.
-
(2007)
Int MS J
, vol.14
, pp. 78-83
-
-
Gay, F.1
-
23
-
-
45549099573
-
Tumor necrosis factor alpha mediates lipopolysaccharide-induced microglial toxicity to developing oligodendrocytes when astrocytes are present
-
10.1523/JNEUROSCI.3995-07.2008, 2677805, 18480288
-
Li J, Ramenaden ER, Peng J, Koito H, Volpe JJ, Rosenberg PA. Tumor necrosis factor alpha mediates lipopolysaccharide-induced microglial toxicity to developing oligodendrocytes when astrocytes are present. J Neurosci 2008, 28:5321-5330. 10.1523/JNEUROSCI.3995-07.2008, 2677805, 18480288.
-
(2008)
J Neurosci
, vol.28
, pp. 5321-5330
-
-
Li, J.1
Ramenaden, E.R.2
Peng, J.3
Koito, H.4
Volpe, J.J.5
Rosenberg, P.A.6
-
24
-
-
79955797827
-
Biphasic activity of CD137 ligand-stimulated monocytes on T cell apoptosis and proliferation
-
10.1189/jlb.1010569, 21330351
-
Kwajah MMS, Mustafa N, Holme AL, Pervaiz S, Schwarz H. Biphasic activity of CD137 ligand-stimulated monocytes on T cell apoptosis and proliferation. J Leukoc Biol 2011, 89:707-720. 10.1189/jlb.1010569, 21330351.
-
(2011)
J Leukoc Biol
, vol.89
, pp. 707-720
-
-
Kwajah, M.M.S.1
Mustafa, N.2
Holme, A.L.3
Pervaiz, S.4
Schwarz, H.5
-
25
-
-
79251565535
-
Species Difference of CD137 Ligand Signaling in Human and Murine Monocytes
-
10.1371/journal.pone.0016129, 3021528, 21264248
-
Tang Q, Jiang D, Shao Z, Martinez Gomez JM, Schwarz H. Species Difference of CD137 Ligand Signaling in Human and Murine Monocytes. PLoS One 2011, 6:e16129. 10.1371/journal.pone.0016129, 3021528, 21264248.
-
(2011)
PLoS One
, vol.6
-
-
Tang, Q.1
Jiang, D.2
Shao, Z.3
Martinez Gomez, J.M.4
Schwarz, H.5
-
26
-
-
0036467421
-
Administration of agonistic anti-4-1BB monoclonal antibody leads to the amelioration of experimental autoimmune encephalomyelitis
-
Sun Y, Lin X, Chen HM, Wu Q, Subudhi SK, Chen L, Fu YX. Administration of agonistic anti-4-1BB monoclonal antibody leads to the amelioration of experimental autoimmune encephalomyelitis. J Immunol 2002, 168:1457-1465.
-
(2002)
J Immunol
, vol.168
, pp. 1457-1465
-
-
Sun, Y.1
Lin, X.2
Chen, H.M.3
Wu, Q.4
Subudhi, S.K.5
Chen, L.6
Fu, Y.X.7
-
27
-
-
80051626171
-
4-1BB triggering ameliorates experimental autoimmune encephalomyelitis by modulating the balance between Th17 and regulatory T cells
-
10.4049/jimmunol.1002681, 21715692
-
Kim YH, Choi BK, Shin SM, Kim CH, Oh HS, Park SH, Lee DG, Lee MJ, Kim KH, Vinay DS, Kwon BS. 4-1BB triggering ameliorates experimental autoimmune encephalomyelitis by modulating the balance between Th17 and regulatory T cells. J Immunol 2011, 187:1120-1128. 10.4049/jimmunol.1002681, 21715692.
-
(2011)
J Immunol
, vol.187
, pp. 1120-1128
-
-
Kim, Y.H.1
Choi, B.K.2
Shin, S.M.3
Kim, C.H.4
Oh, H.S.5
Park, S.H.6
Lee, D.G.7
Lee, M.J.8
Kim, K.H.9
Vinay, D.S.10
Kwon, B.S.11
-
28
-
-
0031007143
-
Monoclonal antibodies against the 4-1BB T-cell activation molecule eradicate established tumors
-
10.1038/nm0697-682, 9176498
-
Melero I, Shuford WW, Newby SA, Aruffo A, Ledbetter JA, Hellstrom KE, Mittler RS, Chen L. Monoclonal antibodies against the 4-1BB T-cell activation molecule eradicate established tumors. Nat Med 1997, 3:682-685. 10.1038/nm0697-682, 9176498.
-
(1997)
Nat Med
, vol.3
, pp. 682-685
-
-
Melero, I.1
Shuford, W.W.2
Newby, S.A.3
Aruffo, A.4
Ledbetter, J.A.5
Hellstrom, K.E.6
Mittler, R.S.7
Chen, L.8
-
29
-
-
4444340010
-
Engagement of the CD137 (4-1BB) costimulatory molecule inhibits and reverses the autoimmune process in collagen-induced arthritis and establishes lasting disease resistance
-
10.1111/j.1365-2567.2004.01952.x, 1782553, 15312139
-
Foell JL, Ez-Mendiondo BI, Diez OH, Holzer U, Ruck P, Bapat AS, Hoffmann MK, Mittler RS, Dannecker GE. Engagement of the CD137 (4-1BB) costimulatory molecule inhibits and reverses the autoimmune process in collagen-induced arthritis and establishes lasting disease resistance. Immunology 2004, 113:89-98. 10.1111/j.1365-2567.2004.01952.x, 1782553, 15312139.
-
(2004)
Immunology
, vol.113
, pp. 89-98
-
-
Foell, J.L.1
Ez-Mendiondo, B.I.2
Diez, O.H.3
Holzer, U.4
Ruck, P.5
Bapat, A.S.6
Hoffmann, M.K.7
Mittler, R.S.8
Dannecker, G.E.9
-
30
-
-
14944342177
-
Stimulation with 4-1BB (CD137) inhibits chronic graft-versus-host disease by inducing activation-induced cell death of donor CD4+ T cells
-
10.1182/blood-2004-06-2080, 15522958
-
Kim J, Choi WS, La S, Suh JH, Kim BS, Cho HR, Kwon BS, Kwon B. Stimulation with 4-1BB (CD137) inhibits chronic graft-versus-host disease by inducing activation-induced cell death of donor CD4+ T cells. Blood 2005, 105:2206-2213. 10.1182/blood-2004-06-2080, 15522958.
-
(2005)
Blood
, vol.105
, pp. 2206-2213
-
-
Kim, J.1
Choi, W.S.2
La, S.3
Suh, J.H.4
Kim, B.S.5
Cho, H.R.6
Kwon, B.S.7
Kwon, B.8
-
31
-
-
0035284861
-
Ligation of 4-1BB (CDw137) regulates graft-versus-host disease, graft-versus-leukemia, and graft rejection in allogeneic bone marrow transplant recipients
-
Blazar BR, Kwon BS, Panoskaltsis-Mortari A, Kwak KB, Peschon J, Taylor PA. Ligation of 4-1BB (CDw137) regulates graft-versus-host disease, graft-versus-leukemia, and graft rejection in allogeneic bone marrow transplant recipients. J Immunol 2001, 166:3174-3183.
-
(2001)
J Immunol
, vol.166
, pp. 3174-3183
-
-
Blazar, B.R.1
Kwon, B.S.2
Panoskaltsis-Mortari, A.3
Kwak, K.B.4
Peschon, J.5
Taylor, P.A.6
-
32
-
-
10744228751
-
Inhibition of cytokines expression in human microglia infected by virulent and non-virulent mycobacteria
-
10.1016/j.neuint.2003.08.012, 14687603
-
Curto M, Reali C, Palmieri G, Scintu F, Schivo ML, Sogos V, Marcialis MA, Ennas MG, Schwarz H, Pozzi G, Gremo F. Inhibition of cytokines expression in human microglia infected by virulent and non-virulent mycobacteria. Neurochem Int 2004, 44:381-392. 10.1016/j.neuint.2003.08.012, 14687603.
-
(2004)
Neurochem Int
, vol.44
, pp. 381-392
-
-
Curto, M.1
Reali, C.2
Palmieri, G.3
Scintu, F.4
Schivo, M.L.5
Sogos, V.6
Marcialis, M.A.7
Ennas, M.G.8
Schwarz, H.9
Pozzi, G.10
Gremo, F.11
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