Effects of minocycline on spatial learning, hippocampal neurogenesis and microglia in aged and adult mice

Behavioural Brain Research

Volumn 242, Issue 1, 2013, Pages 17-24

  Kohman, Rachel A ^a   Bhattacharya, Tushar K ^b   Kilby, Chessa ^b   Bucko, Paula ^b   Rhodes, Justin S ^b  

^a UNIVERSITY OF NORTH CAROLINA WILMINGTON   (United States)

^b UNIVERSITY OF ILLINOIS AT URBANA CHAMPAIGN   (United States)

Author keywords

Aging; CD74; Hippocampus; Iba 1 cytokines; IL 1 ; IL 6; Microglia; Water maze

Indexed keywords

BRAIN PROTEIN; BROXURIDINE; CD74 ANTIGEN; DRINKING WATER; INTERLEUKIN 1BETA; INTERLEUKIN 6; MINOCYCLINE; PROTEIN IBA 1; UNCLASSIFIED DRUG;

AGE DISTRIBUTION; AGED; AGING; ANIMAL BEHAVIOR; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL TISSUE; ANTIGEN EXPRESSION; ARTICLE; BRAIN NERVE CELL; BRAIN TISSUE; CELL ACTIVATION; CELL COUNT; CELL LABELING; CELL SIZE; CELL SURVIVAL; CHRONIC DRUG ADMINISTRATION; COGNITION; COGNITIVE DEFECT; CONCENTRATION RESPONSE; CONTROLLED STUDY; DENTATE GYRUS; DRUG EFFICACY; DRUG MECHANISM; HIPPOCAMPUS; IMMUNOHISTOCHEMISTRY; MALE; MAZE TEST; MICROGLIA; MOUSE; NERVE CELL DIFFERENTIATION; NERVOUS SYSTEM DEVELOPMENT; NONHUMAN; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN EXPRESSION; PROTEIN LOCALIZATION; SPATIAL LEARNING; TREATMENT RESPONSE;

AGING; ANALYSIS OF VARIANCE; ANIMALS; BODY WEIGHT; BROMODEOXYURIDINE; CALCIUM-BINDING PROTEINS; CELL DIFFERENTIATION; CYTOKINES; DRINKING; GENE EXPRESSION; HIPPOCAMPUS; MALE; MAZE LEARNING; MICE; MICROFILAMENT PROTEINS; MICROGLIA; MINOCYCLINE; NEUROGENESIS; PHOSPHOPYRUVATE HYDRATASE; TIME FACTORS;

EID: 84872659111     PISSN: 01664328     EISSN: 18727549     Source Type: Journal    
DOI: 10.1016/j.bbr.2012.12.032     Document Type: Article

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