Optic nerve infarction and post-ischemic inflammation in the rodent model of anterior ischemic optic neuropathy (rAION)

Brain Research

Volumn 1264, Issue , 2009, Pages 67-75

  Zhang, Cheng ^a,c   Guo, Yan ^b   Miller, Neil R ^a   Bernstein, Steven L ^b  

^a JOHNS HOPKINS UNIVERSITY   (United States)

^b UNIVERSITY OF MARYLAND SCHOOL OF MEDICINE   (United States)

^c ZHENGZHOU UNIVERSITY   (China)

Author keywords

AION; Inflammation; Ischemic infarction; Optic nerve; Stroke; White matter

Indexed keywords

CELL MARKER;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CELL INFILTRATION; CONTROLLED STUDY; DISEASE MODEL; HISTOPATHOLOGY; IN VIVO STUDY; INFLAMMATION; ISCHEMIC OPTIC NEUROPATHY; MACROPHAGE ACTIVATION; MICROGLIA; NONARTERITIC ANTERIOR ISCHEMIC OPTIC NEUROPATHY; NONHUMAN; OPTIC NERVE; OPTIC NERVE INFARCTION; PHOTOACTIVATION; PRIORITY JOURNAL; RAT; RETINA;

ANIMALS; AXONS; CELL COUNT; FLUORESCENT ANTIBODY TECHNIQUE; INFLAMMATION; MACROPHAGES; MICROGLIA; OPTIC NERVE; OPTIC NEUROPATHY, ISCHEMIC; RATS; RATS, SPRAGUE-DAWLEY; RETINA; ROSE BENGAL; TIME FACTORS;

RODENTIA;

EID: 63249118590     PISSN: 00068993     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.brainres.2008.12.075     Document Type: Article

References (26)

1. Ahmed Z., Shaw G., Sharma V.P., Yang C., McGowan E., and Dickson D.W. Actin-binding proteins coronin-1a and IBA-1 are effective microglial markers for immunohistochemistry. J. Histochem. Cytochem. 55 (2007) 687-700
2. Arnold A.C. Anterior ischemic optic neuropathy. Semin. Ophthalmol. 10 (1995) 221-233
3. Arnold A.C. Pathogenesis of nonarteritic anterior ischemic optic neuropathy. J. Neuro-Ophthalmol. 23 (2003) 157-163
4. Bernstein S.L., Guo Y., Kelman S.E., Flower R.W., and Johnson M.A. Functional and cellular responses in a novel rodent model of anterior ischemic optic neuropathy. Investig. Ophthalmol. Vis. Sci. 44 (2003) 4153-4162
5. Bernstein S.L., Mehrabian Z., Guo Y., and Moianie N. Estrogen is not neuroprotective in a rodent model of optic nerve stroke. Mol. Vis. 13 (2007) 1920-1925
6. Castellanos M., Castillo J., Garcia M.M., Leira R., Serena J., Chamorro A., and Davalos A. Inflammation-mediated damage in progressing lacunar infarctions: a potential therapeutic target. Stroke 33 (2002) 982-987 2002 Apr
7. David S., and Ousman S.S. Recruiting the immune response to promote axon regeneration in the injured spinal cord. Neuroscientist 8 (2002) 33-41
8. Filbin M.T. Myelin-associated inhibitors of axonal regeneration in the adult mammalian CNS. Nat. Rev. Neurosci. 4 (2003) 703-713
9. Fry E.J., Ho C., and David S. A role for Nogo receptor in macrophage clearance from injured peripheral nerve. Neuron 53 (2007) 649-662
10. Furuya T., Tanaka R., Urabe T., Hayakawa J., Migita M., Shimada T., Mizuno Y., and Mochizuki H. Establishment of modified chimeric mice using GFP bone marrow as a model for neurological disorders. NeuroReport 14 (2003) 629-631
11. Hattenhauer M.G., Leavitt J.A., Hodge D.O., Grill R., and Gray D.T. Incidence of nonarteritic anterior ischemic optic neuropathy. Am. J. Ophthalmol. 123 (1997) 103-107
12. He X.L., Bazan J.F., McDermott G., Park J.B., Wang K., Tessier-Lavigne M., He Z., and Garcia K.C. Structure of the Nogo receptor ectodomain: a recognition module implicated in myelin inhibition. Neuron 38 (2003) 177-185
13. IONDT study group. Ischemic optic neuropathy decompression trial: twenty-four-month update. Arch. Ophthalmol. 118 (2000) 793-798
14. Ito D., Tanaka K., Suzuki S., Dembo T., and Fukuuchi Y. Enhanced expression of Iba1, ionized calcium-binding adapter molecule 1, after transient focal cerebral ischemia in rat brain. Stroke 32 (2001) 1208-1215
15. Knox D.L., Kerrison J.B., and Green W.R. Histopathologic studies of ischemic optic neuropathy. Trans. Am. Ophthalmol. Soc. 98 (2000) 202-203
16. Levin L.A., and Louhab A. Apoptosis of retinal ganglion cells in anterior ischemic optic neuropathy. Arch. Ophthalmol. 114 (1996) 488-491
17. Lieberman M.F., Shahi A., and Green W.R. Embolic ischemic optic neuropathy. Am. J. Ophthalmol. 86 (1978) 206-210
18. Miller N. Anterior ischemic optic neuropathy. In: Miller N.R. (Ed). Walsh and Hoyts Neuro-ophthalmology 1 (1982), Williams and Wilkins, Baltimore 212-226
19. Priller J. Robert feulgen prize lecture. Grenzganger: adult bone marrow cells populate the brain. Histochem. Cell Biol. 120 (2003) 85-91
20. Priller J., Flugel A., Wehner T., Boentert M., Haas C.A., Prinz M., Fernandez-Klett F., Prass K., Bechmann I., de Boer B.A., Frotscher M., Kreutzberg G.W., Persons D.A., and Dirnagl U. Targeting gene-modified hematopoietic cells to the central nervous system: use of green fluorescent protein uncovers microglial engraftment. Nat. Med. 7 (2001) 1356-1361
21. Schori H., Kipnis J., Yoles E., Wolde Mussie E., Ruiz G., Wheeler L.A., and Schwartz M. Vaccination for protection of retinal ganglion cells against death from glutamate cytotoxicity and ocular hypertension: implications for glaucoma. Proc. Natl. Acad. Sci. U. S. A. 98 (2001) 3398-3403
22. Selvaraju R., Bernasconi L., Losberger C., Graber P., Kadi L., Avellana-Adalid V., Picard-Riera N., Van Evercooren A.B., Cirillo R., Kosco-Vilbois M., Feger G., Papoian R., and Boschert U. Osteopontin is upregulated during in vivo demyelination and remyelination and enhances myelin formation in vitro. Mol. Cell Neurosci. 25 (2004) 707-721
23. Slater B.J., Mehrabian Z., Guo Y., Hunter A., and Bernstein S.L. Rodent anterior ischemic optic neuropathy (rAION) induces regional retinal ganglion cell apoptosis with a unique temporal pattern. Investig. Ophthalmol. Vis. Sci. 49 (2008) 3671-3676
24. Tesser R.A., Niendorf E.R., and Levin L.A. The morphology of an infarct in nonarteritic anterior ischemic optic neuropathy. Ophthalmology 110 (2003) 2031-2035
25. Yin Y., Henzl M.T., Lorber B., Nakazawa T., Thomas T.T., Jiang F., Langer R., and Benowitz L.I. Oncomodulin is a macrophage-derived signal for axon regeneration in retinal ganglion cells. Nat. Neurosci. 9 (2006) 843-852
26. Zhang C., Lam T.T., and Tso M.O. Heterogeneous populations of microglia/macrophages in the retina and their activation after retinal ischemia and reperfusion injury. Exp. Eye Res. 81 (2005) 700-709