-
1
-
-
79960845908
-
Fasting vs dietary restriction in cellular protection and cancer treatment: From model organisms to patients
-
Jul
-
Lee C, Longo VD. Fasting vs dietary restriction in cellular protection and cancer treatment: from model organisms to patients. Oncogene 2011 Jul;30(30):3305-3316.
-
(2011)
Oncogene
, vol.30
, Issue.30
, pp. 3305-3316
-
-
Lee, C.1
Longo, V.D.2
-
2
-
-
46149107882
-
Starvation-dependent differential stress resistance protects normal but not cancer cells against high-dose chemotherapy
-
Jun
-
Raffaghello L, Lee C, Safdie FM, Wei M, Madia F, Bianchi G, et al. Starvation-dependent differential stress resistance protects normal but not cancer cells against high-dose chemotherapy. Proc Natl Acad Sci U S A 2008 Jun;105(24):8215-8220.
-
(2008)
Proc Natl Acad Sci U S A
, vol.105
, Issue.24
, pp. 8215-8220
-
-
Raffaghello, L.1
Lee, C.2
Safdie, F.M.3
Wei, M.4
Madia, F.5
Bianchi, G.6
-
3
-
-
77953642929
-
Fasting and cancer treatment in humans: A case series report
-
Dec
-
Safdie FM, Dorff T, Quinn D, Fontana L, Wei M, Lee C, et al. Fasting and cancer treatment in humans: A case series report. Aging (Albany NY) 2009 Dec;1(12):988-1007.
-
(2009)
Aging (Albany NY)
, vol.1
, Issue.12
, pp. 988-1007
-
-
Safdie, F.M.1
Dorff, T.2
Quinn, D.3
Fontana, L.4
Wei, M.5
Lee, C.6
-
4
-
-
33750110683
-
Fuel metabolism in starvation
-
Cahill jr GF. Fuel metabolism in starvation. Annual review of nature. 2006; 26: 1-22.
-
(2006)
Annual review of nature.
, vol.26
, pp. 1-22
-
-
Cahill, G.F.1
-
5
-
-
33645988855
-
The comparative physiology of food deprivation: From feast to famine
-
Wang T, Hung CC, Randall DJ. The comparative physiology of food deprivation: from feast to famine. Annu Rev Physiol 2006;68:223-251.
-
(2006)
Annu Rev Physiol
, vol.68
, pp. 223-251
-
-
Wang, T.1
Hung, C.C.2
Randall, D.J.3
-
6
-
-
0020210193
-
Fasting: The history, pathophysiology and complications
-
Nov
-
Kerndt PR, Naughton JL, Driscoll CE, Loxterkamp DA. Fasting: the history, pathophysiology and complications. West J Med 1982 Nov;137(5):379-399.
-
(1982)
West J Med
, vol.137
, Issue.5
, pp. 379-399
-
-
Kerndt, P.R.1
Naughton, J.L.2
Driscoll, C.E.3
Loxterkamp, D.A.4
-
7
-
-
0014007110
-
Treatment of obesity by total fasting for up to 249 days
-
Nov
-
Thomson TJ, Runcie J, Miller V. Treatment of obesity by total fasting for up to 249 days. Lancet 1966 Nov;2(7471):992-996.
-
(1966)
Lancet
, vol.2
, Issue.7471
, pp. 992-996
-
-
Thomson, T.J.1
Runcie, J.2
Miller, V.3
-
8
-
-
0029742931
-
Disorders of gluconeogenesis
-
van den Berghe G. Disorders of gluconeogenesis. J Inherit Metab Dis 1996;19(4):470-477.
-
(1996)
J Inherit Metab Dis
, vol.19
, Issue.4
, pp. 470-477
-
-
van den Berghe, G.1
-
9
-
-
78649882284
-
Fasting and differential chemotherapy protection in patients
-
Nov
-
Raffaghello L, Safdie F, Bianchi G, Dorff T, Fontana L, Longo VD. Fasting and differential chemotherapy protection in patients. Cell Cycle 2010 Nov;9(22):4474- 4476.
-
(2010)
Cell Cycle
, vol.9
, Issue.22
, pp. 4474-4476
-
-
Raffaghello, L.1
Safdie, F.2
Bianchi, G.3
Dorff, T.4
Fontana, L.5
Longo, V.D.6
-
10
-
-
77951176737
-
Extending healthy life span-from yeast to humans
-
Apr
-
Fontana L, Partridge L, Longo VD. Extending healthy life span-from yeast to humans. Science 2010 Apr;328(5976):321-326.
-
(2010)
Science
, vol.328
, Issue.5976
, pp. 321-326
-
-
Fontana, L.1
Partridge, L.2
Longo, V.D.3
-
11
-
-
60449086832
-
Pretreatment with alternate day modified fast will permit higher dose and frequency of cancer chemotherapy and better cure rates
-
Apr
-
Johnson JB, John S, Laub DR. Pretreatment with alternate day modified fast will permit higher dose and frequency of cancer chemotherapy and better cure rates. Med Hypotheses 2009 Apr;72(4):381-382.
-
(2009)
Med Hypotheses
, vol.72
, Issue.4
, pp. 381-382
-
-
Johnson, J.B.1
John, S.2
Laub, D.R.3
-
12
-
-
84861972253
-
Autophagy and cancer cell metabolism
-
Jun
-
Lozy F, Karantza V. Autophagy and cancer cell metabolism. Semin Cell Dev Biol 2012 Jun;23(4):395-401.
-
(2012)
Semin Cell Dev Biol
, vol.23
, Issue.4
, pp. 395-401
-
-
Lozy, F.1
Karantza, V.2
-
13
-
-
78649338141
-
Autophagy and the integrated stress response
-
Oct
-
Kroemer G, Mariño G, Levine B. Autophagy and the integrated stress response. Mol Cell 2010 Oct;40(2):280- 293.
-
(2010)
Mol Cell
, vol.40
, Issue.2
, pp. 280-293
-
-
Kroemer, G.1
Mariño, G.2
Levine, B.3
-
14
-
-
84984776691
-
Autophagy: Myosin II moves in on autophagosomes
-
Feb
-
Wrighton KH. Autophagy: Myosin II moves in on autophagosomes. Nat Rev Mol Cell Biol 2011 Feb;12(2):77.
-
(2011)
Nat Rev Mol Cell Biol
, vol.12
, Issue.2
, pp. 77
-
-
Wrighton, K.H.1
-
15
-
-
57649184088
-
Control of autophagy by oncogenes and tumor suppressor genes
-
Jan
-
Maiuri MC, Tasdemir E, Criollo A, Morselli E, Vicencio JM, Carnuccio R, et al. Control of autophagy by oncogenes and tumor suppressor genes. Cell Death Differ 2009 Jan;16(1):87-93.
-
(2009)
Cell Death Differ
, vol.16
, Issue.1
, pp. 87-93
-
-
Maiuri, M.C.1
Tasdemir, E.2
Criollo, A.3
Morselli, E.4
Vicencio, J.M.5
Carnuccio, R.6
-
16
-
-
66249108601
-
Understanding the warberg effect: The metabolic requirments of cell proliferation
-
Vander Heiden MG, Cantley LC, Thompson CB. Understanding the warberg effect: the metabolic requirments of cell proliferation. Science 2009;324:1183- 1191.
-
(2009)
Science
, vol.324
, pp. 1183-1191
-
-
Vander Heiden, M.G.1
Cantley, L.C.2
Thompson, C.B.3
-
17
-
-
77957666080
-
Glutaminolysis yields a metabolic by-product that stimulates autophagy
-
CH, Oct
-
Eng CH, Abraham RT; CH. Glutaminolysis yields a metabolic by-product that stimulates autophagy. Autophagy 2010 Oct;6(7):968-970.
-
(2010)
Autophagy
, vol.6
, Issue.7
, pp. 968-970
-
-
Eng, C.H.1
Abraham, R.T.2
-
18
-
-
77953724900
-
Jun proteins inhibit autophagy and induce cell death
-
May
-
Yogev O, Shaulian E. Jun proteins inhibit autophagy and induce cell death. Autophagy 2010 May;6(4):566-567.
-
(2010)
Autophagy
, vol.6
, Issue.4
, pp. 566-567
-
-
Yogev, O.1
Shaulian, E.2
-
19
-
-
77953849832
-
Ammonia: A diffusible factor released by proliferating cells that induces autophagy
-
Mariño G, Kroemer G. Ammonia: a diffusible factor released by proliferating cells that induces autophagy. Sci Signal 2010;3(124):pe19.
-
(2010)
Sci Signal
, vol.3
, Issue.124
-
-
Mariño, G.1
Kroemer, G.2
-
20
-
-
62749196605
-
Caloric restriction and aging: Studies in mice and monkeys
-
Jan
-
Anderson RM, Shanmuganayagam D, Weindruch R. Caloric restriction and aging: studies in mice and monkeys. Toxicol Pathol 2009 Jan;37(1):47-51.
-
(2009)
Toxicol Pathol
, vol.37
, Issue.1
, pp. 47-51
-
-
Anderson, R.M.1
Shanmuganayagam, D.2
Weindruch, R.3
-
21
-
-
33847764645
-
Aging, adiposity, and calorie restriction
-
Mar
-
Fontana L, Klein S. Aging, adiposity, and calorie restriction. JAMA 2007 Mar;297(9):986-994.
-
(2007)
JAMA
, vol.297
, Issue.9
, pp. 986-994
-
-
Fontana, L.1
Klein, S.2
-
22
-
-
27744511769
-
Regulation of yeast replicative life span by TOR and Sch9 in response to nutrients
-
Nov
-
Kaeberlein M, Powers RW III, Steffen KK, Westman EA, Hu D, Dang N, et al. Regulation of yeast replicative life span by TOR and Sch9 in response to nutrients. Science 2005 Nov;310(5751):1193-1196.
-
(2005)
Science
, vol.310
, Issue.5751
, pp. 1193-1196
-
-
Kaeberlein, M.1
Powers, R.W.2
Steffen, K.K.3
Westman, E.A.4
Hu, D.5
Dang, N.6
-
23
-
-
67149130284
-
Tor1/ Sch9-regulated carbon source substitution is as effective as calorie restriction in life span extension
-
May
-
Wei M, Fabrizio P, Madia F, Hu J, Ge H, Li LM, et al. Tor1/ Sch9-regulated carbon source substitution is as effective as calorie restriction in life span extension. PLoS Genet 2009 May;5(5):e1000467.
-
(2009)
PLoS Genet
, vol.5
, Issue.5
-
-
Wei, M.1
Fabrizio, P.2
Madia, F.3
Hu, J.4
Ge, H.5
Li, L.M.6
-
24
-
-
0035853552
-
Regulation of longevity and stress resistance by Sch9 in yeast
-
Apr
-
Fabrizio P, Pozza F, Pletcher SD, Gendron CM, Longo VD. Regulation of longevity and stress resistance by Sch9 in yeast. Science 2001 Apr;292(5515):288-290.
-
(2001)
Science
, vol.292
, Issue.5515
, pp. 288-290
-
-
Fabrizio, P.1
Pozza, F.2
Pletcher, S.D.3
Gendron, C.M.4
Longo, V.D.5
-
25
-
-
0034703217
-
Requirement of NAD and SIR2 for life-span extension by calorie restriction in Saccharomyces cerevisiae
-
Sep
-
Lin SJ, Defossez PA, Guarente L. Requirement of NAD and SIR2 for life-span extension by calorie restriction in Saccharomyces cerevisiae. Science 2000 Sep;289(5487):2126-2128.
-
(2000)
Science
, vol.289
, Issue.5487
, pp. 2126-2128
-
-
Lin, S.J.1
Defossez, P.A.2
Guarente, L.3
-
26
-
-
38949137849
-
Life span extension by calorie restriction depends on Rim15 and transcription factors downstream of Ras/PKA, Tor, and Sch9
-
Jan
-
Wei M, Fabrizio P, Hu J, Ge H, Cheng C, Li L, et al. Life span extension by calorie restriction depends on Rim15 and transcription factors downstream of Ras/PKA, Tor, and Sch9. PLoS Genet 2008 Jan;4(1):e13.
-
(2008)
PLoS Genet
, vol.4
, Issue.1
-
-
Wei, M.1
Fabrizio, P.2
Hu, J.3
Ge, H.4
Cheng, C.5
Li, L.6
-
27
-
-
0031009829
-
Human Bcl-2 reverses survival defects in yeast lacking superoxide dismutase and delays death of wild-type yeast
-
Jun
-
Longo VD, Ellerby LM, Bredesen DE, Valentine JS, Gralla EB. Human Bcl-2 reverses survival defects in yeast lacking superoxide dismutase and delays death of wild-type yeast. J Cell Biol 1997 Jun;137(7):1581-1588.
-
(1997)
J Cell Biol
, vol.137
, Issue.7
, pp. 1581-1588
-
-
Longo, V.D.1
Ellerby, L.M.2
Bredesen, D.E.3
Valentine, J.S.4
Gralla, E.B.5
-
28
-
-
35648995939
-
MSN2 and MSN4 link calorie restriction and TOR to sirtuin-mediated lifespan extension in Saccharomyces cerevisiae
-
Oct
-
Medvedik O, Lamming DW, Kim KD, Sinclair DA. MSN2 and MSN4 link calorie restriction and TOR to sirtuin-mediated lifespan extension in Saccharomyces cerevisiae. PLoS Biol 2007 Oct;5(10):e261.
-
(2007)
PLoS Biol
, vol.5
, Issue.10
-
-
Medvedik, O.1
Lamming, D.W.2
Kim, K.D.3
Sinclair, D.A.4
-
30
-
-
36849087923
-
Caenorhabditis elegans 2007: The premier model for the study of aging
-
Jan
-
Johnson TE. Caenorhabditis elegans 2007: the premier model for the study of aging. Exp Gerontol 2008 Jan;43(1):1-4.
-
(2008)
Exp Gerontol
, vol.43
, Issue.1
, pp. 1-4
-
-
Johnson, T.E.1
-
31
-
-
57749095081
-
Against the oxidative damage theory of aging: Superoxide dismutases protect against oxidative stress but have little or no effect on life span in Caenorhabditis elegans
-
Dec
-
Doonan R, McElwee JJ, Matthijssens F, Walker GA, Houthoofd K, Back P, et al. Against the oxidative damage theory of aging: superoxide dismutases protect against oxidative stress but have little or no effect on life span in Caenorhabditis elegans. Genes Dev 2008 Dec;22(23):3236-3241.
-
(2008)
Genes Dev
, vol.22
, Issue.23
, pp. 3236-3241
-
-
Doonan, R.1
McElwee, J.J.2
Matthijssens, F.3
Walker, G.A.4
Houthoofd, K.5
Back, P.6
-
32
-
-
38349103636
-
Separating cause from effect: How does insulin/IGF signalling control lifespan in worms, flies and mice?
-
Feb
-
Piper MD, Selman C, McElwee JJ, Partridge L. Separating cause from effect: how does insulin/IGF signalling control lifespan in worms, flies and mice? J Intern Med 2008 Feb;263(2):179-191.
-
(2008)
J Intern Med
, vol.263
, Issue.2
, pp. 179-191
-
-
Piper, M.D.1
Selman, C.2
McElwee, J.J.3
Partridge, L.4
-
33
-
-
34447528668
-
Type 5 adenylyl cyclase disruption increases longevity and protects against stress
-
Jul
-
Yan L, Vatner DE, O'Connor JP, Ivessa A, Ge H, Chen W, et al. Type 5 adenylyl cyclase disruption increases longevity and protects against stress. Cell 2007 Jul;130(2):247-258.
-
(2007)
Cell
, vol.130
, Issue.2
, pp. 247-258
-
-
Yan, L.1
Vatner, D.E.2
O'Connor, J.P.3
Ivessa, A.4
Ge, H.5
Chen, W.6
-
34
-
-
40549146580
-
Role of dFOXO in lifespan extension by dietary restriction in Drosophila melanogaster: Not required, but its activity modulates the response
-
Mar
-
Giannakou ME, Goss M, Partridge L. Role of dFOXO in lifespan extension by dietary restriction in Drosophila melanogaster: not required, but its activity modulates the response. Aging Cell 2008 Mar;7(2):187-198.
-
(2008)
Aging Cell
, vol.7
, Issue.2
, pp. 187-198
-
-
Giannakou, M.E.1
Goss, M.2
Partridge, L.3
-
35
-
-
23844551318
-
Minireview: Role of the growth hormone/ insulin-like growth factor system in mammalian aging
-
Sep
-
Bartke A. Minireview: role of the growth hormone/ insulin-like growth factor system in mammalian aging. Endocrinology 2005 Sep;146(9):3718-3723.
-
(2005)
Endocrinology
, vol.146
, Issue.9
, pp. 3718-3723
-
-
Bartke, A.1
-
36
-
-
34247360791
-
Hormonal regulation of longevity in mammals
-
May
-
Brown-Borg HM. Hormonal regulation of longevity in mammals. Ageing Res Rev 2007 May;6(1):28-45.
-
(2007)
Ageing Res Rev
, vol.6
, Issue.1
, pp. 28-45
-
-
Brown-Borg, H.M.1
-
37
-
-
46649092289
-
Effect of Ames dwarfism and caloric restriction on spontaneous DNA mutation frequency in different mouse tissues
-
Sep
-
Garcia AM, Busuttil RA, Calder RB, Dollé ME, Diaz V, McMahan CA, et al. Effect of Ames dwarfism and caloric restriction on spontaneous DNA mutation frequency in different mouse tissues. Mech Ageing Dev 2008 Sep;129(9):528-533.
-
(2008)
Mech Ageing Dev
, vol.129
, Issue.9
, pp. 528-533
-
-
Garcia, A.M.1
Busuttil, R.A.2
Calder, R.B.3
Dollé, M.E.4
Diaz, V.5
McMahan, C.A.6
-
38
-
-
33847198926
-
Patients with congenital deficiency of IGF-I seem protected from the development of malignancies: A preliminary report
-
Feb
-
Shevah O, Laron Z. Patients with congenital deficiency of IGF-I seem protected from the development of malignancies: a preliminary report. Growth Horm IGF Res 2007 Feb;17(1):54-57.
-
(2007)
Growth Horm IGF Res
, vol.17
, Issue.1
, pp. 54-57
-
-
Shevah, O.1
Laron, Z.2
-
39
-
-
2342647592
-
Long-term calorie restriction is highly effective in reducing the risk for atherosclerosis in humans
-
Apr
-
Fontana L, Meyer TE, Klein S, Holloszy JO. Long-term calorie restriction is highly effective in reducing the risk for atherosclerosis in humans. Proc Natl Acad Sci U S A 2004 Apr;101(17):6659-6663.
-
(2004)
Proc Natl Acad Sci U S A
, vol.101
, Issue.17
, pp. 6659-6663
-
-
Fontana, L.1
Meyer, T.E.2
Klein, S.3
Holloszy, J.O.4
-
40
-
-
76749169812
-
Reduced levels of IGF-I mediate differential protection of normal and cancer cells in response to fasting and improve chemotherapeutic index
-
Feb
-
Lee C, Safdie FM, Raffaghello L, Wei M, Madia F, Parrella E, et al. Reduced levels of IGF-I mediate differential protection of normal and cancer cells in response to fasting and improve chemotherapeutic index. Cancer Res 2010 Feb;70(4):1564-1572.
-
(2010)
Cancer Res
, vol.70
, Issue.4
, pp. 1564-1572
-
-
Lee, C.1
Safdie, F.M.2
Raffaghello, L.3
Wei, M.4
Madia, F.5
Parrella, E.6
-
41
-
-
79959350253
-
Extending life span by increasing oxidative stress
-
Jul
-
Ristow M, Schmeisser S. Extending life span by increasing oxidative stress. Free Radic Biol Med 2011 Jul;51(2):327- 336.
-
(2011)
Free Radic Biol Med
, vol.51
, Issue.2
, pp. 327-336
-
-
Ristow, M.1
Schmeisser, S.2
-
42
-
-
34748850786
-
Glucose restriction extends Caenorhabditis elegans life span by inducing mitochondrial respiration and increasing oxidative stress
-
Oct
-
Schulz TJ, Zarse K, Voigt A, Urban N, Birringer M, Ristow M. Glucose restriction extends Caenorhabditis elegans life span by inducing mitochondrial respiration and increasing oxidative stress. Cell Metab 2007 Oct;6(4):280-293.
-
(2007)
Cell Metab
, vol.6
, Issue.4
, pp. 280-293
-
-
Schulz, T.J.1
Zarse, K.2
Voigt, A.3
Urban, N.4
Birringer, M.5
Ristow, M.6
-
43
-
-
79959547070
-
Mitochondria-mediated hormetic response in life span extension of calorie-restricted Saccharomyces cerevisiae
-
Jun
-
Sharma PK, Agrawal V, Roy N. Mitochondria-mediated hormetic response in life span extension of calorie-restricted Saccharomyces cerevisiae. Age (Dordr) 2011 Jun;33(2):143-154.
-
(2011)
Age (Dordr)
, vol.33
, Issue.2
, pp. 143-154
-
-
Sharma, P.K.1
Agrawal, V.2
Roy, N.3
-
44
-
-
77649341027
-
Lifespan extension by calorie restriction relies on the Sty1 MAP kinase stress pathway
-
Mar
-
Zuin A, Carmona M, Morales-Ivorra I, Gabrielli N, Vivancos AP, Ayté J, et al. Lifespan extension by calorie restriction relies on the Sty1 MAP kinase stress pathway. EMBO J 2010 Mar;29(5):981-991.
-
(2010)
EMBO J
, vol.29
, Issue.5
, pp. 981-991
-
-
Zuin, A.1
Carmona, M.2
Morales-Ivorra, I.3
Gabrielli, N.4
Vivancos, A.P.5
Ayté, J.6
-
45
-
-
0037130175
-
Calorie restriction extends Saccharomyces cerevisiae lifespan by increasing respiration
-
Jul
-
Lin SJ, Kaeberlein M, Andalis AA, Sturtz LA, Defossez PA, Culotta VC, et al. Calorie restriction extends Saccharomyces cerevisiae lifespan by increasing respiration. Nature 2002 Jul;418(6895):344-348.
-
(2002)
Nature
, vol.418
, Issue.6895
, pp. 344-348
-
-
Lin, S.J.1
Kaeberlein, M.2
Andalis, A.A.3
Sturtz, L.A.4
Defossez, P.A.5
Culotta, V.C.6
-
46
-
-
26844558334
-
Calorie restriction promotes mitochondrial biogenesis by inducing the expression of eNOS
-
Oct
-
Nisoli E, Tonello C, Cardile A, Cozzi V, Bracale R, Tedesco L, et al. Calorie restriction promotes mitochondrial biogenesis by inducing the expression of eNOS. Science 2005 Oct;310(5746):314-317.
-
(2005)
Science
, vol.310
, Issue.5746
, pp. 314-317
-
-
Nisoli, E.1
Tonello, C.2
Cardile, A.3
Cozzi, V.4
Bracale, R.5
Tedesco, L.6
-
47
-
-
32444437067
-
Calorie restriction induces mitochondrial biogenesis and bioenergetic efficiency
-
Feb
-
López-Lluch G, Hunt N, Jones B, Zhu M, Jamieson H, Hilmer S, et al. Calorie restriction induces mitochondrial biogenesis and bioenergetic efficiency. Proc Natl Acad Sci U S A 2006 Feb;103(6):1768-1773.
-
(2006)
Proc Natl Acad Sci U S A
, vol.103
, Issue.6
, pp. 1768-1773
-
-
López-Lluch, G.1
Hunt, N.2
Jones, B.3
Zhu, M.4
Jamieson, H.5
Hilmer, S.6
-
48
-
-
33646779855
-
Minireview: Implication of mitochondria in insulin secretion and action
-
Jun
-
Wiederkehr A, Wollheim CB. Minireview: implication of mitochondria in insulin secretion and action. Endocrinology 2006 Jun;147(6):2643-2649.
-
(2006)
Endocrinology
, vol.147
, Issue.6
, pp. 2643-2649
-
-
Wiederkehr, A.1
Wollheim, C.B.2
-
49
-
-
38549101188
-
Quality control of mitochondria: Protection against neurodegeneration and ageing
-
Jan
-
Tatsuta T, Langer T. Quality control of mitochondria: protection against neurodegeneration and ageing. EMBO J 2008 Jan;27(2):306-314.
-
(2008)
EMBO J
, vol.27
, Issue.2
, pp. 306-314
-
-
Tatsuta, T.1
Langer, T.2
-
50
-
-
77049308856
-
Aging: A theory based on free radical and radiation chemistry
-
Jul
-
Harman D. Aging: a theory based on free radical and radiation chemistry. J Gerontol 1956 Jul;11(3):298-300.
-
(1956)
J Gerontol
, vol.11
, Issue.3
, pp. 298-300
-
-
Harman, D.1
-
51
-
-
77952548782
-
How increased oxidative stress promotes longevity and metabolic health: The concept of mitochondrial hormesis (mitohormesis)
-
Jun
-
Ristow M, Zarse K. How increased oxidative stress promotes longevity and metabolic health: The concept of mitochondrial hormesis (mitohormesis). Exp Gerontol 2010 Jun;45(6):410-418.
-
(2010)
Exp Gerontol
, vol.45
, Issue.6
, pp. 410-418
-
-
Ristow, M.1
Zarse, K.2
-
52
-
-
67649204729
-
Overexpression of catalase targeted to mitochondria attenuates murine cardiac aging
-
Jun
-
Dai DF, Santana LF, Vermulst M, Tomazela DM, Emond MJ, MacCoss MJ, et al. Overexpression of catalase targeted to mitochondria attenuates murine cardiac aging. Circulation 2009 Jun;119(21):2789-2797.
-
(2009)
Circulation
, vol.119
, Issue.21
, pp. 2789-2797
-
-
Dai, D.F.1
Santana, L.F.2
Vermulst, M.3
Tomazela, D.M.4
Emond, M.J.5
McCoss, M.J.6
-
53
-
-
34250838974
-
The role of hormesis in life extension by dietary restriction
-
Masoro EJ. The role of hormesis in life extension by dietary restriction. Interdiscip Top Gerontol 2007;35:1-17.
-
(2007)
Interdiscip Top Gerontol
, vol.35
, pp. 1-17
-
-
Masoro, E.J.1
-
54
-
-
84863229916
-
Fasting cycles retard growth of tumors and sensitize a range of cancer cell types to chemotherapy
-
Lee C, Raffaghello L, Brandhorst S, Safdie FM, Bianchi G, Montalvo AM et al. Fasting cycles retard growth of tumors and sensitize a range of cancer cell types to chemotherapy. Sci Transl Med. 2012;4:124ra27.
-
(2012)
Sci Transl Med.
, vol.4
-
-
Lee, C.1
Raffaghello, L.2
Brandhorst, S.3
Safdie, F.M.4
Bianchi, G.5
Montalvo, A.M.6
-
55
-
-
84862821594
-
Starvation, detoxification, and multidrug resistance in cancer therapy
-
Feb-Apr
-
Lee C, Raffaghello L, Longo VD. Starvation, detoxification, and multidrug resistance in cancer therapy. Drug Resist Updat 2012 Feb-Apr;15(1-2):114-122.
-
(2012)
Drug Resist Updat
, vol.15
, Issue.1-2
, pp. 114-122
-
-
Lee, C.1
Raffaghello, L.2
Longo, V.D.3
-
56
-
-
0025978756
-
The molecular basis of carbon-starvation-induced general resistance in Escherichia coli
-
Jan
-
Matin A. The molecular basis of carbon-starvation-induced general resistance in Escherichia coli. Mol Microbiol 1991 Jan;5(1):3-10.
-
(1991)
Mol Microbiol
, vol.5
, Issue.1
, pp. 3-10
-
-
Matin, A.1
-
57
-
-
14244270260
-
Analysis of gene expression in Escherichia coli in response to changes of growth-limiting nutrient in chemostat cultures
-
Apr
-
Hua Q, Yang C, Oshima T, Mori H, Shimizu K. Analysis of gene expression in Escherichia coli in response to changes of growth-limiting nutrient in chemostat cultures. Appl Environ Microbiol 2004 Apr;70(4):2354-2366.
-
(2004)
Appl Environ Microbiol
, vol.70
, Issue.4
, pp. 2354-2366
-
-
Hua, Q.1
Yang, C.2
Oshima, T.3
Mori, H.4
Shimizu, K.5
-
58
-
-
38949137849
-
Life span extension by calorie restriction depends on Rim15 and transcription factors downstream of Ras/PKA, Tor, and Sch9
-
Jan
-
Wei M, Fabrizio P, Hu J, Ge H, Cheng C, Li L, et al. Life span extension by calorie restriction depends on Rim15 and transcription factors downstream of Ras/PKA, Tor, and Sch9. PLoS Genet 2008 Jan;4(1):e13.
-
(2008)
PLoS Genet
, vol.4
, Issue.1
-
-
Wei, M.1
Fabrizio, P.2
Hu, J.3
Ge, H.4
Cheng, C.5
Li, L.6
-
59
-
-
67149130284
-
Tor1/Sch9-regulated carbon source substitution is as effective as calorie restriction in life span extension
-
May
-
Wei M, Fabrizio P, Madia F, Hu J, Ge H, Li LM, et al. Tor1/Sch9-regulated carbon source substitution is as effective as calorie restriction in life span extension. PLoS Genet 2009 May;5(5):e1000467.
-
(2009)
PLoS Genet
, vol.5
, Issue.5
-
-
Wei, M.1
Fabrizio, P.2
Madia, F.3
Hu, J.4
Ge, H.5
Li, L.M.6
-
60
-
-
59649120539
-
Signalling through RHEB-1 mediates intermittent fasting-induced longevity in C. elegans
-
Feb
-
Honjoh S, Yamamoto T, Uno M, Nishida E. Signalling through RHEB-1 mediates intermittent fasting-induced longevity in C. elegans. Nature 2009 Feb;457(7230):726-730.
-
(2009)
Nature
, vol.457
, Issue.7230
, pp. 726-730
-
-
Honjoh, S.1
Yamamoto, T.2
Uno, M.3
Nishida, E.4
-
61
-
-
70350365110
-
Glucose shortens the life span of C. elegans by downregulating DAF-16/FOXO activity and aquaporin gene expression
-
Nov
-
Lee SJ, Murphy CT, Kenyon C. Glucose shortens the life span of C. elegans by downregulating DAF-16/FOXO activity and aquaporin gene expression. Cell Metab 2009 Nov;10(5):379-391.
-
(2009)
Cell Metab
, vol.10
, Issue.5
, pp. 379-391
-
-
Lee, S.J.1
Murphy, C.T.2
Kenyon, C.3
-
62
-
-
34347391453
-
Diet dependent longevity and hypoxic tolerance of adult Drosophila melanogaster
-
May-Jun
-
Vigne P, Frelin C. Diet dependent longevity and hypoxic tolerance of adult Drosophila melanogaster. Mech Ageing Dev 2007 May-Jun;128(5-6):401-406.
-
(2007)
Mech Ageing Dev
, vol.128
, Issue.5-6
, pp. 401-406
-
-
Vigne, P.1
Frelin, C.2
-
63
-
-
23944507152
-
Starvation and oxidative stress resistance in Drosophila are mediated through the eIF4E-binding protein, d4E-BP
-
Aug
-
Tettweiler G, Miron M, Jenkins M, Sonenberg N, Lasko PF. Starvation and oxidative stress resistance in Drosophila are mediated through the eIF4E-binding protein, d4E-BP. Genes Dev 2005 Aug;19(16):1840-1843.
-
(2005)
Genes Dev
, vol.19
, Issue.16
, pp. 1840-1843
-
-
Tettweiler, G.1
Miron, M.2
Jenkins, M.3
Sonenberg, N.4
Lasko, P.F.5
-
64
-
-
0034614637
-
The hallmarks of cancer
-
Jan
-
Hanahan D, Weinberg RA. The hallmarks of cancer. Cell 2000 Jan;100(1):57-70.
-
(2000)
Cell
, vol.100
, Issue.1
, pp. 57-70
-
-
Hanahan, D.1
Weinberg, R.A.2
-
65
-
-
0027529827
-
Ras activation by insulin and epidermal growth factor through enhanced exchange of guanine nucleotides on p21ras
-
Jan
-
Medema RH, de Vries-Smits AM, van der Zon GC, Maassen JA, Bos JL. Ras activation by insulin and epidermal growth factor through enhanced exchange of guanine nucleotides on p21ras. Mol Cell Biol 1993 Jan;13(1):155-162.
-
(1993)
Mol Cell Biol
, vol.13
, Issue.1
, pp. 155-162
-
-
Medema, R.H.1
de Vries-Smits, A.M.2
van der Zon, G.C.3
Maassen, J.A.4
Bos, J.L.5
-
66
-
-
79953038262
-
PTEN loss in the continuum of common cancers, rare syndromes and mouse models
-
Apr
-
Hollander MC, Blumenthal GM, Dennis PA. PTEN loss in the continuum of common cancers, rare syndromes and mouse models. Nat Rev Cancer 2011 Apr;11(4):289-301.
-
(2011)
Nat Rev Cancer
, vol.11
, Issue.4
, pp. 289-301
-
-
Hollander, M.C.1
Blumenthal, G.M.2
Dennis, P.A.3
-
68
-
-
0003880161
-
-
4th edn. Garland Science, New York
-
Alberts B, Johnson A, Lewis J, Raff M, Roberts K, Walter P. Molecular Biology of the Cell, 4th edn. Garland Science2002, New York.
-
(2002)
Molecular Biology of the Cell
-
-
Alberts, B.1
Johnson, A.2
Lewis, J.3
Raff, M.4
Roberts, K.5
Walter, P.6
-
69
-
-
57049132739
-
Glucose metabolism inhibits apoptosis in neurons and cancer cells by redox inactivation of cytochrome c
-
Dec
-
Vaughn AE, Deshmukh M. Glucose metabolism inhibits apoptosis in neurons and cancer cells by redox inactivation of cytochrome c. Nat Cell Biol 2008 Dec;10(12):1477-1483.
-
(2008)
Nat Cell Biol
, vol.10
, Issue.12
, pp. 1477-1483
-
-
Vaughn, A.E.1
Deshmukh, M.2
-
70
-
-
33845500072
-
Long-term low-protein, low-calorie diet and endurance exercise modulate metabolic factors associated with cancer risk
-
Dec
-
Fontana L, Klein S, Holloszy JO. Long-term low-protein, low-calorie diet and endurance exercise modulate metabolic factors associated with cancer risk. Am J Clin Nutr 2006 Dec;84(6):1456-1462.
-
(2006)
Am J Clin Nutr
, vol.84
, Issue.6
, pp. 1456-1462
-
-
Fontana, L.1
Klein, S.2
Holloszy, J.O.3
-
71
-
-
84884194961
-
The need for holistic cancer care framework: Breast cancer care as an example
-
Sep
-
Al-Moundhri M. The need for holistic cancer care framework: breast cancer care as an example. Oman Med J 2013 Sep;28(5):300-301.
-
(2013)
Oman Med J
, vol.28
, Issue.5
, pp. 300-301
-
-
Al-Moundhri, M.1
|