메뉴 건너뛰기




Volumn 25, Issue 9, 2014, Pages 1602-1608

Promises and Pitfalls of Intracellular Delivery of Proteins

Author keywords

[No Author keywords available]

Indexed keywords

VIRUSES;

EID: 84922140266     PISSN: 10431802     EISSN: 15204812     Source Type: Journal    
DOI: 10.1021/bc500320j     Document Type: Review
Times cited : (251)

References (62)
  • 1
    • 79951771258 scopus 로고    scopus 로고
    • Regulation of stem cell signaling by nanoparticle-mediated intracellular protein delivery
    • Shah, D. A., Kwon, S. J., Bale, S. S., Banerjee, A., Dordick, J. S., and Kane, R. S. (2011) Regulation of stem cell signaling by nanoparticle-mediated intracellular protein delivery Biomaterials 32, 3210 - 3219
    • (2011) Biomaterials , vol.32 , pp. 3210-3219
    • Shah, D.A.1    Kwon, S.J.2    Bale, S.S.3    Banerjee, A.4    Dordick, J.S.5    Kane, R.S.6
  • 2
    • 78650370883 scopus 로고    scopus 로고
    • Intracellular delivery of a protein antigen with an endosomal-releasing polymer enhances CD8 T-cell production and prophylactic vaccine efficacy
    • Foster, S., Duvall, C. L., Crownover, E. F., Hoffman, A. S., and Stayton, P. S. (2010) Intracellular delivery of a protein antigen with an endosomal-releasing polymer enhances CD8 T-cell production and prophylactic vaccine efficacy Bioconjugate Chem. 21, 2205 - 2212
    • (2010) Bioconjugate Chem. , vol.21 , pp. 2205-2212
    • Foster, S.1    Duvall, C.L.2    Crownover, E.F.3    Hoffman, A.S.4    Stayton, P.S.5
  • 4
    • 84877671384 scopus 로고    scopus 로고
    • Therapeutic potential of cell-penetrating peptides
    • Vasconcelos, L., Pärn, K., and Langel, U. (2013) Therapeutic potential of cell-penetrating peptides Ther. Delivery 4, 573 - 591
    • (2013) Ther. Delivery , vol.4 , pp. 573-591
    • Vasconcelos, L.1    Pärn, K.2    Langel, U.3
  • 5
    • 84862702122 scopus 로고    scopus 로고
    • Clinical impact of serum proteins on drug delivery
    • Kratz, F. and Elsadek, B. (2012) Clinical impact of serum proteins on drug delivery J. Controlled Release 161, 429 - 445
    • (2012) J. Controlled Release , vol.161 , pp. 429-445
    • Kratz, F.1    Elsadek, B.2
  • 6
    • 13444263549 scopus 로고    scopus 로고
    • Clathrin- and non-clathrin-mediated endocytic regulation of cell signalling
    • Le Roy, C. and Wrana, J. L. (2005) Clathrin- and non-clathrin-mediated endocytic regulation of cell signalling Nat. Rev. Mol. Cell. Biol. 6, 112 - 126
    • (2005) Nat. Rev. Mol. Cell. Biol. , vol.6 , pp. 112-126
    • Le Roy, C.1    Wrana, J.L.2
  • 7
    • 84871393255 scopus 로고    scopus 로고
    • Enhancing endosomal escape of transduced proteins by photochemical internalisation
    • Mellert, K., Lamla, M., Scheffzek, K., Wittig, R., and Kaufmann, D. (2012) Enhancing endosomal escape of transduced proteins by photochemical internalisation PLoS One 7, e52473
    • (2012) PLoS One , vol.7 , pp. e52473
    • Mellert, K.1    Lamla, M.2    Scheffzek, K.3    Wittig, R.4    Kaufmann, D.5
  • 8
    • 84859589783 scopus 로고    scopus 로고
    • Intracellular protein delivery and gene transfection by electroporation using a microneedle electrode array
    • Choi, S. O., Kim, Y. C., Lee, J. W., Park, J. H., Prausnitz, M. R., and Allen, M. G. (2012) Intracellular protein delivery and gene transfection by electroporation using a microneedle electrode array Small 8, 1081 - 1091
    • (2012) Small , vol.8 , pp. 1081-1091
    • Choi, S.O.1    Kim, Y.C.2    Lee, J.W.3    Park, J.H.4    Prausnitz, M.R.5    Allen, M.G.6
  • 11
    • 84922162097 scopus 로고    scopus 로고
    • Cell-penetrating peptide (CPP)-conjugated proteins is an efficient tool for manipulation of human mesenchymal stromal cells
    • Jo, J., Hong, S., Choi, W. Y., and Lee, D. R. (2014) Cell-penetrating peptide (CPP)-conjugated proteins is an efficient tool for manipulation of human mesenchymal stromal cells Sci. Rep. 4, 4378
    • (2014) Sci. Rep. , vol.4 , pp. 4378
    • Jo, J.1    Hong, S.2    Choi, W.Y.3    Lee, D.R.4
  • 12
    • 2342595835 scopus 로고    scopus 로고
    • Transducible TAT-HA fusogenic peptide enhances escape of TAT-fusion proteins after lipid raft macropinocytosis
    • Wadia, J. S., Stan, R. V., and Dowdy, S. F. (2004) Transducible TAT-HA fusogenic peptide enhances escape of TAT-fusion proteins after lipid raft macropinocytosis Nat. Med. 10, 310 - 315
    • (2004) Nat. Med. , vol.10 , pp. 310-315
    • Wadia, J.S.1    Stan, R.V.2    Dowdy, S.F.3
  • 13
    • 79959365312 scopus 로고    scopus 로고
    • Mechanisms of cellular uptake of cell-penetrating peptides
    • Madani, F., Lindberg, S., Langel, U., Futaki, S., and Gräslund, A. (2011) Mechanisms of cellular uptake of cell-penetrating peptides J. Biophys. 2011, 414729
    • (2011) J. Biophys. , vol.2011 , pp. 414729
    • Madani, F.1    Lindberg, S.2    Langel, U.3    Futaki, S.4    Gräslund, A.5
  • 14
    • 34250835903 scopus 로고    scopus 로고
    • A comprehensive model for the cellular uptake of cationic cell-penetrating peptides
    • Duchardt, F., Fotin-Mleczek, M., Schwarz, H., Fischer, R., and Brock, R. (2007) A comprehensive model for the cellular uptake of cationic cell-penetrating peptides Traffic 8, 848 - 866
    • (2007) Traffic , vol.8 , pp. 848-866
    • Duchardt, F.1    Fotin-Mleczek, M.2    Schwarz, H.3    Fischer, R.4    Brock, R.5
  • 15
    • 84900988583 scopus 로고    scopus 로고
    • The uptake of arginine-rich cell-penetrating peptides: Putting the puzzle together
    • Brock, R. (2014) The uptake of arginine-rich cell-penetrating peptides: putting the puzzle together Bioconjugate Chem. 25, 863 - 868
    • (2014) Bioconjugate Chem. , vol.25 , pp. 863-868
    • Brock, R.1
  • 16
    • 81255189096 scopus 로고    scopus 로고
    • Efficient cellular delivery of β-galactosidase mediated by NrTPs, a new family of cell-penetrating peptides
    • Rodrigues, M., de la Torre, B. G., Radis-Baptista, G., Santos, N. C., and Andreu, D. (2011) Efficient cellular delivery of β-galactosidase mediated by NrTPs, a new family of cell-penetrating peptides Bioconjugate Chem. 22, 2339 - 2344
    • (2011) Bioconjugate Chem. , vol.22 , pp. 2339-2344
    • Rodrigues, M.1    De La Torre, B.G.2    Radis-Baptista, G.3    Santos, N.C.4    Andreu, D.5
  • 17
    • 84864439768 scopus 로고    scopus 로고
    • Targeted gene knockout by direct delivery of zinc-finger nuclease proteins
    • Gaj, T., Guo, J., Kato, Y., Sirk, S. J., and Barbas, C. F., 3rd. (2012) Targeted gene knockout by direct delivery of zinc-finger nuclease proteins Nat. Methods 9, 805 - 807
    • (2012) Nat. Methods , vol.9 , pp. 805-807
    • Gaj, T.1    Guo, J.2    Kato, Y.3    Sirk, S.J.4    Barbas, C.F.5
  • 18
    • 84863912070 scopus 로고    scopus 로고
    • Star-like oligo-arginyl-maltotriosyl derivatives as novel cell-penetrating enhancers for the intracellular delivery of colloidal therapeutic systems
    • Bersani, S., Salmaso, S., Mastrotto, F., Ravazzolo, E., Semenzato, A., and Caliceti, P. (2012) Star-like oligo-arginyl-maltotriosyl derivatives as novel cell-penetrating enhancers for the intracellular delivery of colloidal therapeutic systems Bioconjugate Chem. 23, 1415 - 1425
    • (2012) Bioconjugate Chem. , vol.23 , pp. 1415-1425
    • Bersani, S.1    Salmaso, S.2    Mastrotto, F.3    Ravazzolo, E.4    Semenzato, A.5    Caliceti, P.6
  • 19
    • 84866370878 scopus 로고    scopus 로고
    • Caspase-activated cell-penetrating peptides reveal temporal coupling between endosomal release and apoptosis in an RGC-5 cell model
    • Johnson, J. R., Kocher, B., Barnett, E. M., Marasa, J., and Piwnica-Worms, D. (2012) Caspase-activated cell-penetrating peptides reveal temporal coupling between endosomal release and apoptosis in an RGC-5 cell model Bioconjugate Chem. 23, 1783 - 1793
    • (2012) Bioconjugate Chem. , vol.23 , pp. 1783-1793
    • Johnson, J.R.1    Kocher, B.2    Barnett, E.M.3    Marasa, J.4    Piwnica-Worms, D.5
  • 20
    • 79959365312 scopus 로고    scopus 로고
    • Mechanisms of cellular uptake of cell-penetrating peptides
    • Madani, F., Lindberg, S., Langel, U., Futaki, S., and Gräslund, A. (2011) Mechanisms of cellular uptake of cell-penetrating peptides J. Biophys. 2011, 414729
    • (2011) J. Biophys. , vol.2011 , pp. 414729
    • Madani, F.1    Lindberg, S.2    Langel, U.3    Futaki, S.4    Gräslund, A.5
  • 22
    • 84893816004 scopus 로고    scopus 로고
    • Endosomal escape: A bottleneck in intracellular delivery
    • Shete, H. K., Prabhu, R. H., and Patravale, V. B. (2014) Endosomal escape: a bottleneck in intracellular delivery J. Nanosci. Nanotechnol. 14, 460 - 474
    • (2014) J. Nanosci. Nanotechnol. , vol.14 , pp. 460-474
    • Shete, H.K.1    Prabhu, R.H.2    Patravale, V.B.3
  • 23
    • 84889889091 scopus 로고    scopus 로고
    • Cell-penetrating peptide secures an efficient endosomal escape of an intact cargo upon a brief photo-induction
    • Räägel, H., Hein, M., Kriiska, A., Säälik, P., Florén, A., Langel, Ü., and Pooga, M. (2013) Cell-penetrating peptide secures an efficient endosomal escape of an intact cargo upon a brief photo-induction Cell. Mol. Life Sci. 70, 4825 - 5839
    • (2013) Cell. Mol. Life Sci. , vol.70 , pp. 4825-5839
    • Räägel, H.1    Hein, M.2    Kriiska, A.3    Säälik, P.4    Florén, A.5    Langel, Ü.6    Pooga, M.7
  • 26
    • 80052801329 scopus 로고    scopus 로고
    • Distribution of KAI-9803, a novel δ-protein kinase C inhibitor, after intravenous administration to rats
    • Miyaji, Y., Walter, S., Chen, L., Kurihara, A., Ishizuka, T., Saito, M., Kawai, K., and Okazaki, O. (2011) Distribution of KAI-9803, a novel δ-protein kinase C inhibitor, after intravenous administration to rats Drug Metab. Dispos. 39, 1946 - 1953
    • (2011) Drug Metab. Dispos. , vol.39 , pp. 1946-1953
    • Miyaji, Y.1    Walter, S.2    Chen, L.3    Kurihara, A.4    Ishizuka, T.5    Saito, M.6    Kawai, K.7    Okazaki, O.8
  • 27
    • 79952804470 scopus 로고    scopus 로고
    • Self-assembled virus-like particles from rotavirus structural protein VP6 for targeted drug delivery
    • Zhao, Q., Chen, W., Chen, Y., Zhang, L., Zhang, J., and Zhang, Z. (2011) Self-assembled virus-like particles from rotavirus structural protein VP6 for targeted drug delivery Bioconjugate Chem. 22, 346 - 352
    • (2011) Bioconjugate Chem. , vol.22 , pp. 346-352
    • Zhao, Q.1    Chen, W.2    Chen, Y.3    Zhang, L.4    Zhang, J.5    Zhang, Z.6
  • 28
    • 77953948721 scopus 로고    scopus 로고
    • Lentivirus-based virus-like particles as a new protein delivery tool
    • Muratori, C., Bona, R., and Federico, M. (2010) Lentivirus-based virus-like particles as a new protein delivery tool Methods Mol. Biol. 614, 111 - 124
    • (2010) Methods Mol. Biol. , vol.614 , pp. 111-124
    • Muratori, C.1    Bona, R.2    Federico, M.3
  • 31
    • 84862944657 scopus 로고    scopus 로고
    • Engineering and identifying supercharged proteins for macromolecule delivery into mammalian cells
    • Thompson, D. B., Cronican, J. J., and Liu, D. R. (2012) Engineering and identifying supercharged proteins for macromolecule delivery into mammalian cells Methods Enzymol. 503, 293 - 319
    • (2012) Methods Enzymol. , vol.503 , pp. 293-319
    • Thompson, D.B.1    Cronican, J.J.2    Liu, D.R.3
  • 34
    • 84878369282 scopus 로고    scopus 로고
    • Nanoparticle mediated non-covalent drug delivery
    • Doane, T. and Burda, C. (2013) Nanoparticle mediated non-covalent drug delivery Adv. Drug Delivery Rev. 65, 607 - 621
    • (2013) Adv. Drug Delivery Rev. , vol.65 , pp. 607-621
    • Doane, T.1    Burda, C.2
  • 35
    • 84891788399 scopus 로고    scopus 로고
    • Chitosan-assisted immobilization of serratiopeptidase on magnetic nanoparticles, characterization and its target delivery
    • Kumar, S., Jana, A. K., Dhamija, I., and Maiti, M. (2014) Chitosan-assisted immobilization of serratiopeptidase on magnetic nanoparticles, characterization and its target delivery J. Drug Targeting 22, 123 - 137
    • (2014) J. Drug Targeting , vol.22 , pp. 123-137
    • Kumar, S.1    Jana, A.K.2    Dhamija, I.3    Maiti, M.4
  • 36
    • 84891822166 scopus 로고    scopus 로고
    • Delivery of chemically glycosylated cytochrome c immobilized in mesoporous silica nanoparticles induces apoptosis in HeLa cancer cells
    • Méndez, J., Morales Cruz, M., Delgado, Y., Figueroa, C. M., Orellano, E. A., Morales, M., Monteagudo, A., and Griebenow, K. (2014) Delivery of chemically glycosylated cytochrome c immobilized in mesoporous silica nanoparticles induces apoptosis in HeLa cancer cells Mol. Pharmacol. 11, 102 - 111
    • (2014) Mol. Pharmacol. , vol.11 , pp. 102-111
    • Méndez, J.1    Morales Cruz, M.2    Delgado, Y.3    Figueroa, C.M.4    Orellano, E.A.5    Morales, M.6    Monteagudo, A.7    Griebenow, K.8
  • 38
    • 84870386548 scopus 로고    scopus 로고
    • Brain-targeted delivery of protein using chitosan- and RVG peptide-conjugated, pluronic-based nano-carrier
    • Kim, J. Y., Choi, W. I., Kim, Y. H., and Tae, G. (2012) Brain-targeted delivery of protein using chitosan- and RVG peptide-conjugated, pluronic-based nano-carrier Biomaterials 34, 1170 - 1178
    • (2012) Biomaterials , vol.34 , pp. 1170-1178
    • Kim, J.Y.1    Choi, W.I.2    Kim, Y.H.3    Tae, G.4
  • 39
    • 84891755243 scopus 로고    scopus 로고
    • Intracellular delivery of universal proteins using a lysine headgroup containing cationic liposomes: Decipering the uptake mechanism
    • Sarker, S. R., Hokama, R., and Takeoka, S. (2014) Intracellular delivery of universal proteins using a lysine headgroup containing cationic liposomes: decipering the uptake mechanism Mol. Pharmacol. 11, 164 - 174
    • (2014) Mol. Pharmacol. , vol.11 , pp. 164-174
    • Sarker, S.R.1    Hokama, R.2    Takeoka, S.3
  • 40
    • 33746687880 scopus 로고    scopus 로고
    • Intracelluar delivery of proteins in complexes with oligoarginine-modified liposomes and the effect of oligoarginine length
    • Furuhata, M., Kawakami, H., Toma, K., Hattori, Y., and Maitani, Y. (2006) Intracelluar delivery of proteins in complexes with oligoarginine-modified liposomes and the effect of oligoarginine length Bioconjugate Chem. 17, 935 - 942
    • (2006) Bioconjugate Chem. , vol.17 , pp. 935-942
    • Furuhata, M.1    Kawakami, H.2    Toma, K.3    Hattori, Y.4    Maitani, Y.5
  • 41
    • 84891755243 scopus 로고    scopus 로고
    • Intracellular delivery of universal proteins using a lysine headgroup containing cationic liposomes: Deciphering the uptake mechanism
    • Sarker, S. R., Hokama, R., and Takeoka, S. (2014) Intracellular delivery of universal proteins using a lysine headgroup containing cationic liposomes: deciphering the uptake mechanism Mol. Pharmacol. 11, 164 - 174
    • (2014) Mol. Pharmacol. , vol.11 , pp. 164-174
    • Sarker, S.R.1    Hokama, R.2    Takeoka, S.3
  • 42
    • 84862786862 scopus 로고    scopus 로고
    • Protein encapsulation in unilamellar liposomes: High encapsulation efficiency and a novel technique to assess lipid-protein interaction
    • Xu, X., Costa, A., and Burgess, D. J. (2012) Protein encapsulation in unilamellar liposomes: high encapsulation efficiency and a novel technique to assess lipid-protein interaction Pharm. Res. 29, 1919 - 1931
    • (2012) Pharm. Res. , vol.29 , pp. 1919-1931
    • Xu, X.1    Costa, A.2    Burgess, D.J.3
  • 43
    • 84895923647 scopus 로고    scopus 로고
    • Characterization of a laboratory-scale container for freezing protein solutions with detailed evaluation of a freezing process simulation
    • Roessl, U., Jajcevic, D., Leitgeb, S., Khinast, J. G., and Nidetzky, B. (2014) Characterization of a laboratory-scale container for freezing protein solutions with detailed evaluation of a freezing process simulation J. Pharm. Sci. 103, 417 - 426
    • (2014) J. Pharm. Sci. , vol.103 , pp. 417-426
    • Roessl, U.1    Jajcevic, D.2    Leitgeb, S.3    Khinast, J.G.4    Nidetzky, B.5
  • 44
    • 84866875931 scopus 로고    scopus 로고
    • Oral delivery of peptides and proteins using lipid-based drug delivery systems
    • Li, P., Nielsen, H. M., and Müllertz, A. (2012) Oral delivery of peptides and proteins using lipid-based drug delivery systems Expert Opin. Drug Delivery 9, 1289 - 1304
    • (2012) Expert Opin. Drug Delivery , vol.9 , pp. 1289-1304
    • Li, P.1    Nielsen, H.M.2    Müllertz, A.3
  • 45
    • 84855169716 scopus 로고    scopus 로고
    • Efficient protein transduction method using cationic peptides and lipids
    • Yamaguchi, K., Inoue, M., and Goshima, N. (2011) Efficient protein transduction method using cationic peptides and lipids J. Biomed. Biotechnol. 2011, 872065
    • (2011) J. Biomed. Biotechnol. , vol.2011 , pp. 872065
    • Yamaguchi, K.1    Inoue, M.2    Goshima, N.3
  • 46
    • 84858593795 scopus 로고    scopus 로고
    • Encapsulation of polyunsaturated fatty acid esters with solid lipid particles
    • Holser, R. (2012) Encapsulation of polyunsaturated fatty acid esters with solid lipid particles Lipid Insight 5, 1 - 5
    • (2012) Lipid Insight , vol.5 , pp. 1-5
    • Holser, R.1
  • 47
    • 84888315416 scopus 로고    scopus 로고
    • Solid lipid particles for oral delivery of peptide and protein drugs I - Elucidating the release mechanism of lysozyme during lipolysis
    • Christophersen, P. C., Zhang, L., Yang, M., Nielsen, H. M., Müllertz, A., and Mu, H. (2013) Solid lipid particles for oral delivery of peptide and protein drugs I - elucidating the release mechanism of lysozyme during lipolysis Eur. J. Pharm. Biopharm. 85, 473 - 480
    • (2013) Eur. J. Pharm. Biopharm. , vol.85 , pp. 473-480
    • Christophersen, P.C.1    Zhang, L.2    Yang, M.3    Nielsen, H.M.4    Müllertz, A.5    Mu, H.6
  • 48
    • 84868354242 scopus 로고    scopus 로고
    • Delivery of quantum dot-siRNA nanoplexes in SK-N-SH cells for BACE1 gene silencing and intracellular imaging
    • Li, S., Liu, Z., Ji, F., Xiao, Z., Wang, M., Peng, Y., Zhang, Y., Liu, L., Liang, Z., and Li, F. (2012) Delivery of quantum dot-siRNA nanoplexes in SK-N-SH cells for BACE1 gene silencing and intracellular imaging Mol. Ther. Nucleic Acids 1, e20
    • (2012) Mol. Ther. Nucleic Acids , vol.1 , pp. e20
    • Li, S.1    Liu, Z.2    Ji, F.3    Xiao, Z.4    Wang, M.5    Peng, Y.6    Zhang, Y.7    Liu, L.8    Liang, Z.9    Li, F.10
  • 49
    • 84876907110 scopus 로고    scopus 로고
    • Hydrophobic and membrane permeable polyethylenimine nanoparticles efficiently deliver nucleic acids in vitro and in vivo
    • Tripathi, S. K., Singh, V. P., Gupta, K. C., and Kumar, P. (2013) Hydrophobic and membrane permeable polyethylenimine nanoparticles efficiently deliver nucleic acids in vitro and in vivo J. Mater. Chem. B 1, 2515 - 2524
    • (2013) J. Mater. Chem. B , vol.1 , pp. 2515-2524
    • Tripathi, S.K.1    Singh, V.P.2    Gupta, K.C.3    Kumar, P.4
  • 50
    • 84884685775 scopus 로고    scopus 로고
    • Carboxymethyl chitosan-poly(amidoamine) dendrimer core-shell nanoparticles for intracellular lysozyme delivery
    • Zhang, X., Zhao, J., Wen, Y., Zhu, C., Yang, J., and Yao, F. (2013) Carboxymethyl chitosan-poly(amidoamine) dendrimer core-shell nanoparticles for intracellular lysozyme delivery Carbohyd. Polym. 98, 1326 - 1334
    • (2013) Carbohyd. Polym. , vol.98 , pp. 1326-1334
    • Zhang, X.1    Zhao, J.2    Wen, Y.3    Zhu, C.4    Yang, J.5    Yao, F.6
  • 51
    • 84881583767 scopus 로고    scopus 로고
    • Endosomolytic reducible polymeric electrolytes for cytosolic protein delivery
    • Tian, L., Kang, H. C., and Bae, Y. H. (2013) Endosomolytic reducible polymeric electrolytes for cytosolic protein delivery Biomacromolecules 14, 2570 - 2581
    • (2013) Biomacromolecules , vol.14 , pp. 2570-2581
    • Tian, L.1    Kang, H.C.2    Bae, Y.H.3
  • 52
    • 0036736954 scopus 로고    scopus 로고
    • A biomimetic pH-responsive polymer directs endosomal release and intracellular delivery of an endocytosed antibody complex
    • Lackey, C. A., Press, O. W., Hoffman, A. S., and Stayton, P. S. (2002) A biomimetic pH-responsive polymer directs endosomal release and intracellular delivery of an endocytosed antibody complex Bioconjugate Chem. 13, 996 - 1001
    • (2002) Bioconjugate Chem. , vol.13 , pp. 996-1001
    • Lackey, C.A.1    Press, O.W.2    Hoffman, A.S.3    Stayton, P.S.4
  • 53
    • 78650370883 scopus 로고    scopus 로고
    • Intracellular delivery of a protein antigen with an endosomal-releasing polymer enhances CD8 T-Cell production and prophylactic vaccine efficacy
    • Foster, S., Duvall, C. L., Crownover, E. F., Hoffman, A. S., and Stayton, P. S. (2010) Intracellular delivery of a protein antigen with an endosomal-releasing polymer enhances CD8 T-Cell production and prophylactic vaccine efficacy Bioconjugate Chem. 21, 2205 - 2212
    • (2010) Bioconjugate Chem. , vol.21 , pp. 2205-2212
    • Foster, S.1    Duvall, C.L.2    Crownover, E.F.3    Hoffman, A.S.4    Stayton, P.S.5
  • 54
    • 42949178917 scopus 로고    scopus 로고
    • Self-assembled cationic nanogels for intracellular protein delivery
    • Ayame, H., Morimoto, N., and Akiyoshi, K. (2008) Self-assembled cationic nanogels for intracellular protein delivery Bioconjugate Chem. 19, 882 - 890
    • (2008) Bioconjugate Chem. , vol.19 , pp. 882-890
    • Ayame, H.1    Morimoto, N.2    Akiyoshi, K.3
  • 55
    • 84855956522 scopus 로고    scopus 로고
    • Degradable thermoresponsive nanogels for protein encapsulation and controlled release
    • Bhuchar, N., Sunasee, R., Ishihara, K., Thundat, T., and Narain, R. (2012) Degradable thermoresponsive nanogels for protein encapsulation and controlled release Bioconjugate Chem. 23, 75 - 83
    • (2012) Bioconjugate Chem. , vol.23 , pp. 75-83
    • Bhuchar, N.1    Sunasee, R.2    Ishihara, K.3    Thundat, T.4    Narain, R.5
  • 56
    • 84863075939 scopus 로고    scopus 로고
    • pH and reduction dual-bioresponsive polymersomes for efficient intracelluar protein delivery
    • Zhang, J., Wu, L., Meng, F., Wang, Z., Deng, C., Liu, H., and Zhong, Z. (2012) pH and reduction dual-bioresponsive polymersomes for efficient intracelluar protein delivery Langmuir 28, 2056 - 2065
    • (2012) Langmuir , vol.28 , pp. 2056-2065
    • Zhang, J.1    Wu, L.2    Meng, F.3    Wang, Z.4    Deng, C.5    Liu, H.6    Zhong, Z.7
  • 57
    • 77649294324 scopus 로고    scopus 로고
    • Intracellular delivery of a membrane-impermeable enzyme in active form using functionalized gold nanoparticles
    • Ghosh, P., Yang, X., Arvizo, R., Zhu, Z. J., Agasti, S. S., Mo, Z., and Rotello, V. M. (2010) Intracellular delivery of a membrane-impermeable enzyme in active form using functionalized gold nanoparticles J. Am. Chem. Soc. 132, 2642 - 2645
    • (2010) J. Am. Chem. Soc. , vol.132 , pp. 2642-2645
    • Ghosh, P.1    Yang, X.2    Arvizo, R.3    Zhu, Z.J.4    Agasti, S.S.5    Mo, Z.6    Rotello, V.M.7
  • 59
    • 84893598647 scopus 로고    scopus 로고
    • The amine content of PEGylated chitosan Bombyxmori nanoparticles acts as a trigger for protein delivery
    • Vasquez, D., Milusheva, R., Baumann, P., Constantin, D., Chami, M., and Palivan, C. G. (2014) The amine content of PEGylated chitosan Bombyxmori nanoparticles acts as a trigger for protein delivery Langmuir 30, 965 - 975
    • (2014) Langmuir , vol.30 , pp. 965-975
    • Vasquez, D.1    Milusheva, R.2    Baumann, P.3    Constantin, D.4    Chami, M.5    Palivan, C.G.6
  • 61
    • 79956078790 scopus 로고    scopus 로고
    • Redox-responsive nanocapsules for intracellular protein delivery
    • Zhao, M., Biswas, A., Hu, B., Joo, K. I., Wang, P., Gu, Z., and Tang, Y. (2011) Redox-responsive nanocapsules for intracellular protein delivery Biomaterials 32, 5223 - 5230
    • (2011) Biomaterials , vol.32 , pp. 5223-5230
    • Zhao, M.1    Biswas, A.2    Hu, B.3    Joo, K.I.4    Wang, P.5    Gu, Z.6    Tang, Y.7


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.