Measurement of heart rate and Q-T interval in the conscious mouse

American Journal of Physiology - Heart and Circulatory Physiology

Volumn 274, Issue 3 43-3, 1998, Pages

  Mitchell, Gary F ^a   Jeron, Andreas ^a   Koren, Gideon ^a  

^a BRIGHAM AND WOMEN S HOSPITAL   (United States)

Author keywords

Computer analysis; Electrocardiographic intervals; Ketamine; Mouse models; Signal averaging

Indexed keywords

KETAMINE;

ANIMAL EXPERIMENT; ARTICLE; CONSCIOUSNESS; FEMALE; HEART RATE; MALE; MEASUREMENT; MOUSE; NONHUMAN; PRIORITY JOURNAL; QT INTERVAL; RR INTERVAL; SIGNAL AVERAGED ELECTROCARDIOGRAPHY; TELEMETRY; TRANSGENIC MOUSE;

EID: 0031944052     PISSN: 03636135     EISSN: None     Source Type: Journal    
DOI: 10.1152/ajpheart.1998.274.3.h747     Document Type: Article

References (10)

1. Babila, T., A. Moscucci, H. Wang, F. E. Weaver, and G. Koren. Assembly of mammalian voltage-gated potassium channels: evidence for an important role of the first transmembrane segment. Neuron 12: 615-626, 1994.
2. Bazett, H. C. An analysis of the time-relations of electrocardiograms. Heart 7: 353-370, 1920.
3. Berul, C. I., M. J. Aronovitz, P. J. Wang, and M. E. Mendelsohn. In vivo cardiac electrophysiology studies in the mouse. Circulation 94: 2641-2648, 1996.
4. Berul, C. I., M. E. Christe, M. J. Aronovitz, C. E. Seidman, J. G. Seidman, and M. E. Mendelsohn. Electrophysiological abnormalities and arrhythmias in aMHC mutant familial hypertrophic cardiomyopathy mice. J. Clin. Invest. 99: 570-576, 1997.
5. Bland, J. M., and D. G. Altman. Statistical methods for assessing agreement between two methods of clinical measurement. Lancet 1: 301-310, 1986.
6. Craelius, W., M. Restivo, M. A. Assadi, and N. El-Sherif. Criteria for optimal averaging of cardiac signals. IEEE Trans. Biomed. Eng. BME-33: 957-966, 1986.
7. Kramer, K., S. A. B. E. van Acker, H. P. Voss, J. A. Grimbergen, W. J. F. van der Vijgh, and A. Bast. Use of telemetry to record electrocardiogram and heart rate in freely moving mice. J. Pharmacol. Toxicol. Methods 30: 209-215, 1993.
8. London, B., A. Jeron, J. Zhou, P. Buckett, X. Han, G. F. Mitchell, and G. Koren. Long QT and ventricular arrhythmias in transgenic mice expressing the N-terminus and first transmembrahe segment of a voltage-gated potassium channel. Proc. Natl. Acad. Sci. In press.
9. Opitz, C. F., G. F. Mitchell, M. A. Pfeffer, and J. M. Pfeffer. Arrhythmias and death after conronary artery occlusion in the rat: continuous telemetric ECG monitoring in conscious, untethered rats. Circulation 92: 253-261, 1995.
10. Van Acker, S. A. B. E., K. Kramer, J. A. Grimbergen, W. J. F. van der Vijgh, and A. Bast. Doxorubicin-induced chronic cardiotoxicity measured in freely moving mice. Contrib. Oncol. 48: 30-39, 1995.