A transient outward potassium current activator recapitulates the electrocardiographic manifestations of Brugada syndrome

Cardiovascular Research

Volumn 81, Issue 4, 2009, Pages 686-694

  Calloe, Kirstine ^a   Cordeiro, Jonathan M ^b   Di Diego, José M ^b   Hansen, Rie S ^c   Grunnet, Morten ^a,c   Olesen, Søren Peter ^a   Antzelevitch, Charles ^b  

^a UNIVERSITY OF COPENHAGEN   (Denmark)

^b MASONIC MEDICAL RESEARCH LABORATORY   (United States)

^c NEUROSEARCH A S   (Denmark)

Author keywords

Arrhythmia; Brugada syndrome; Ito; Re entry; Transient outward potassium current

Indexed keywords

CALCIUM CHANNEL BLOCKING AGENT; NS 5806; SODIUM CHANNEL BLOCKING AGENT; UNCLASSIFIED DRUG; UREA DERIVATIVE;

ANIMAL CELL; ARTICLE; BRUGADA SYNDROME; CHEMICAL STRUCTURE; CONTROLLED STUDY; DOG; ELECTROCARDIOGRAM; ELECTROCARDIOGRAPHY; ENDOCARDIUM; EPICARDIUM; FEMALE; MALE; NONHUMAN; PATCH CLAMP; PHENOTYPE; POLYMORPHIC VENTRICULAR TACHYCARDIA; POTASSIUM TRANSPORT; PRIORITY JOURNAL;

ACTION POTENTIALS; ANIMALS; BRUGADA SYNDROME; DOGS; DOSE-RESPONSE RELATIONSHIP, DRUG; ELECTROCARDIOGRAPHY; ENDOCARDIUM; HEART VENTRICLES; MEMBRANE TRANSPORT MODULATORS; MUTATION; MYOCYTES, CARDIAC; PERICARDIUM; PHENYLUREA COMPOUNDS; POTASSIUM; POTASSIUM CHANNELS; TETRAZOLES; TIME FACTORS;

EID: 60149087552     PISSN: 00086363     EISSN: 17553245     Source Type: Journal    
DOI: 10.1093/cvr/cvn339     Document Type: Article

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