Targeted deletion of kcne2 impairs ventricular repolarization via disruption of IK,slow1 and Ito,f

FASEB Journal

Volumn 22, Issue 10, 2008, Pages 3648-3660

  Roepke, Torsten K ^a   Kontogeorgis, Andrianos ^b,c   Ovanez, Christopher ^d   Xu, Xianghua ^a   Young, Jeffrey B ^a   Purtell, Kerry ^a   Goldstein, Peter A ^a   Christini, David J ^a   Peters, Nicholas S ^b   Akar, Fadi G ^d   Gutstein, David E ^c   Lerner, Daniel J ^e   Abbott, Geoffrey W ^a  

^a WEILL CORNELL MEDICAL COLLEGE   (United States)

^b ST MARY S HOSPITAL   (United Kingdom)

^c NEW YORK UNIVERSITY SCHOOL OF MEDICINE   (United States)

^d MOUNT SINAI SCHOOL OF MEDICINE   (United States)

^e FoxHollow Technologies   (United States)

Author keywords

Cardiac arrhythmia; Kv1.5; Kv4.2; Long QT syndrome; MiRP1; Potassium channel

Indexed keywords

POTASSIUM CHANNEL KCNE2; POTASSIUM CHANNEL KV1.5; SHAL POTASSIUM CHANNEL; ETHER DERIVATIVE; INHALATION ANESTHETIC AGENT; KCNE2 PROTEIN, MOUSE; SEVOFLURANE; VOLTAGE GATED POTASSIUM CHANNEL;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CONTROLLED STUDY; ELECTROCARDIOGRAM; GENE DELETION; GENE DISRUPTION; GENE MAPPING; GENE MUTATION; HEART ARRHYTHMIA; IMMUNOPRECIPITATION; MOUSE; NONHUMAN; PRIORITY JOURNAL; WESTERN BLOTTING; ANIMAL; DRUG EFFECT; GENETICS; HEART MUSCLE CONDUCTION SYSTEM; HEART VENTRICLE; HUMAN; LONG QT SYNDROME; METABOLISM; MOUSE MUTANT; MUSCLE CELL; PATHOLOGY; PATHOPHYSIOLOGY;

MURINAE;

ANESTHETICS, INHALATION; ANIMALS; HEART CONDUCTION SYSTEM; HEART VENTRICLES; HUMANS; IMMUNOPRECIPITATION; KV1.5 POTASSIUM CHANNEL; LONG QT SYNDROME; METHYL ETHERS; MICE; MICE, MUTANT STRAINS; MUSCLE CELLS; POTASSIUM CHANNELS, VOLTAGE-GATED; SEQUENCE DELETION; SHAL POTASSIUM CHANNELS;

EID: 54049142897     PISSN: 08926638     EISSN: None     Source Type: Journal    
DOI: 10.1096/fj.08-110171     Document Type: Article

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