ATM regulates cell fate choice upon p53 activation by modulating mitochondrial turnover and ROS levels http://www.tandfonline.com/doi/pdf/10.4161/15384101.2014.973330

Cell Cycle

Volumn 14, Issue 1, 2015, Pages 56-63

  Sullivan, Kelly D ^a   Palaniappan, Vignesh V ^a   Espinosa, Joaqun M ^a  

^a UNIVERSITY OF COLORADO SCHOOL OF MEDICINE   (United States)

Author keywords

Apoptosis; ATM; Autophagy; Mitochondria; Nutlin 3; P53; Reactive oxygen species; ROS

Indexed keywords

ATM PROTEIN; NUTLIN 3; PROTEIN BAX; PROTEIN BID; PROTEIN P53; REACTIVE OXYGEN METABOLITE; 2-MORPHOLIN-4-YL-6-THIANTHREN-1-YL-PYRAN-4-ONE; CASPASE 8; HEAT SHOCK PROTEIN; IMIDAZOLE DERIVATIVE; MORPHOLINE DERIVATIVE; NUCLEAR PROTEIN; PIPERAZINE DERIVATIVE; PMAIP1 PROTEIN, HUMAN; PROTEIN BCL 2; PYRONE DERIVATIVE; SESN1 PROTEIN, HUMAN; SESN2 PROTEIN, HUMAN; SMALL INTERFERING RNA;

APOPTOSIS; ARTICLE; AUTOPHAGY; CELL FATE; CELL KILLING; CONTROLLED STUDY; ENZYME INHIBITION; GENE; GENE EXPRESSION; GENE TARGETING; HUMAN; HUMAN CELL; HUMAN TISSUE; MITOCHONDRIAL DYNAMICS; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN INTERACTION; ANTAGONISTS AND INHIBITORS; CHEMISTRY; DRUG EFFECTS; GENETICS; HCT116 CELL LINE; METABOLISM; MITOCHONDRION; RNA INTERFERENCE;

APOPTOSIS; ATAXIA TELANGIECTASIA MUTATED PROTEINS; AUTOPHAGY; BCL-2-ASSOCIATED X PROTEIN; BH3 INTERACTING DOMAIN DEATH AGONIST PROTEIN; CASPASE 8; HCT116 CELLS; HEAT-SHOCK PROTEINS; HUMANS; IMIDAZOLES; MITOCHONDRIA; MITOCHONDRIAL TURNOVER; MORPHOLINES; NUCLEAR PROTEINS; PIPERAZINES; PROTO-ONCOGENE PROTEINS C-BCL-2; PYRONES; REACTIVE OXYGEN SPECIES; RNA INTERFERENCE; RNA, SMALL INTERFERING; TUMOR SUPPRESSOR PROTEIN P53;

EID: 84921853118     PISSN: 15384101     EISSN: 15514005     Source Type: Journal    
DOI: 10.4161/15384101.2014.973330     Document Type: Article

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