Inhibition of 14q32 MicroRNAs miR-329, miR-487b, miR-494, and miR-495 increases neovascularization and blood flow recovery after ischemia

Circulation Research

Volumn 115, Issue 8, 2014, Pages 696-708

  Welten, Sabine M J ^a   Bastiaansen, Antonius J N M ^a   De Jong, Rob C M ^a   De Vries, Margreet R ^a   Peters, Erna A B ^a   Boonstra, Martin C ^a   Sheikh, Soren P ^b   Monica, Nicola La ^c   Kandimalla, Ekambar R ^c   Quax, Paul H A ^a   Yael Nossent A ^a  

^a LEIDEN UNIVERSITY MEDICAL CENTER   (Netherlands)

^b ODENSE UNIVERSITY HOSPITAL   (Denmark)

^c HYBRIDON INC   (United States)

Author keywords

Collateral blood circulation; microRNAs; Peripheral arterial disease; Physiologic angiogenesis

Indexed keywords

GENE SILENCING OLIGONUCLEOTIDE 329; GENE SILENCING OLIGONUCLEOTIDE 487B; GENE SILENCING OLIGONUCLEOTIDE 494; GENE SILENCING OLIGONUCLEOTIDE 495; MICRORNA; MICRORNA 329; MICRORNA 487B; MICRORNA 494; MICRORNA 495; OLIGONUCLEOTIDE; UNCLASSIFIED DRUG; MIRN329 MICRORNA, HUMAN; MIRN487 MICRORNA, HUMAN; MIRN494 MICRORNA, HUMAN; MIRN495 MICRORNA, HUMAN;

ANGIOGENESIS; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTERY DIAMETER; ARTICLE; BINDING SITE; CAPILLARY DENSITY; CELL PROLIFERATION; CHROMOSOME 14Q; COLLATERAL CIRCULATION; CONTROLLED STUDY; CORONARY ARTERY BLOOD FLOW; ENDOTHELIUM CELL; GENE CLUSTER; GENE EXPRESSION REGULATION; HUMAN; HUMAN CELL; IN VITRO STUDY; LASER DOPPLER FLOWMETRY; LIMB ISCHEMIA; MICROARRAY ANALYSIS; MOUSE; MYOCARDIAL PERFUSION IMAGING; MYOFIBROBLAST; NONHUMAN; PRIORITY JOURNAL; SOLEUS MUSCLE; UPREGULATION; ANIMAL; BLOOD FLOW VELOCITY; BLOOD VESSEL; C57BL MOUSE; CELL CULTURE; CHROMOSOME 14; DNA MICROARRAY; GENE EXPRESSION PROFILING; GENE SILENCING; GENETICS; HELA CELL LINE; HINDLIMB; ISCHEMIA; MALE; METABOLISM; PATHOPHYSIOLOGY; PHYSIOLOGY; SKELETAL MUSCLE; SMOOTH MUSCLE FIBER; VASCULARIZATION;

ANIMALS; BLOOD FLOW VELOCITY; BLOOD VESSELS; CELL PROLIFERATION; CELLS, CULTURED; CHROMOSOMES, HUMAN, PAIR 14; ENDOTHELIAL CELLS; GENE EXPRESSION PROFILING; GENE SILENCING; HELA CELLS; HINDLIMB; HUMANS; ISCHEMIA; MALE; MICE; MICE, INBRED C57BL; MICRORNAS; MUSCLE, SKELETAL; MYOCYTES, SMOOTH MUSCLE; OLIGONUCLEOTIDE ARRAY SEQUENCE ANALYSIS; OLIGONUCLEOTIDES;

EID: 84921767137     PISSN: 00097330     EISSN: 15244571     Source Type: Journal    
DOI: 10.1161/CIRCRESAHA.114.304747     Document Type: Article

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