The 14q32 MicroRNA-487b targets the antiapoptotic insulin receptor substrate 1 in hypertension-induced remodeling of the aorta

Annals of Surgery

Volumn 258, Issue 5, 2013, Pages 743-753

  Yael Nossent A ^a,b,c   Eskildsen, Tilde V ^b   Andersen, Lene B ^b   Bie, Peter ^b   Brønnum, Hasse ^b   Schneider, Mikael ^b   Andersen, Ditte C ^b   Welten, Sabine M J ^a   Jeppesen, Pia L ^b   Hamming, Jaap F ^a   Hansen, Jakob L ^c,d   Quax, Paul H ^a   Sheikh, Søren P ^b  

^a LEIDEN UNIVERSITY MEDICAL CENTER   (Netherlands)

^b UNIVERSITY OF SOUTHERN DENMARK   (Denmark)

^c UNIVERSITY OF COPENHAGEN   (Denmark)

^d NOVO NORDISK A S   (Denmark)

Author keywords

Aneurysm; Angiotensin II; Aorta; Hypertension; Insulin receptor substrate 1; MicroRNA 487b

Indexed keywords

ANGIOTENSIN II; INSULIN RECEPTOR SUBSTRATE 1; MICRORNA; MICRORNA 487B; UNCLASSIFIED DRUG;

3' UNTRANSLATED REGION; ADVENTITIA; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL TISSUE; AORTA WALL; ARTICLE; CELL PROLIFERATION; CELL SURVIVAL; CONTINUOUS INFUSION; CONTROLLED STUDY; DOWN REGULATION; FEMALE; FIBROBLAST; GENE EXPRESSION; HUMAN; HUMAN CELL; HUMAN TISSUE; HYPERTENSION; IMMUNOHISTOCHEMISTRY; IN VITRO STUDY; INTIMA; NONHUMAN; POLYMERASE CHAIN REACTION; PRIMARY CULTURE; PRIORITY JOURNAL; RANDOMIZED CONTROLLED TRIAL; RAT; REPORTER GENE; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; SMOOTH MUSCLE FIBER; STARVATION; TUNICA MEDIA; UMBILICAL CORD; UPREGULATION;

ANGIOTENSIN II; ANIMALS; AORTA; APOPTOSIS; BLOTTING, WESTERN; CELL PROLIFERATION; CELL SURVIVAL; FEMALE; FIBROBLASTS; GLUCOSE; HUMANS; HYPERTENSION; IMMUNOHISTOCHEMISTRY; INSULIN RECEPTOR SUBSTRATE PROTEINS; LUCIFERASES; MICRORNAS; RATS; RATS, SPRAGUE-DAWLEY; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; SIGNAL TRANSDUCTION; TUMOR CELLS, CULTURED; UMBILICAL CORD;

EID: 84886093134     PISSN: 00034932     EISSN: 15281140     Source Type: Journal    
DOI: 10.1097/SLA.0b013e3182a6aac0     Document Type: Article

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