Vascular endothelial cell-specific MicroRNA-15a inhibits angiogenesis in hindlimb ischemia

Journal of Biological Chemistry

Volumn 287, Issue 32, 2012, Pages 27055-27064

  Yin, Ke Jie ^a   Olsen, Karl ^b   Hamblin, Milton ^a   Zhang, Jifeng ^a   Schwendeman, Steven P ^b   Chen, Y Eugene ^a  

^a UNIVERSITY OF MICHIGAN HEALTH SYSTEM   (United States)

^b UNIVERSITY OF MICHIGAN   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ANGIOGENESIS; BLOOD FLOW; CELL DIFFERENTIATION; CELL MIGRATION; HIND LIMBS; LUCIFERASE REPORTER ASSAYS; OVER-EXPRESSION; PATHOLOGICAL CONDITIONS; POTENTIAL MECHANISM; REAL-TIME PCR; THERAPEUTIC STRATEGY; TRANSGENICS; TUBE FORMATION; VASCULAR ENDOTHELIAL CELLS; VESSEL FORMATION;

BIOASSAY; BLOOD VESSELS; PLANTS (BOTANY); POLYMERASE CHAIN REACTION; RNA;

ENDOTHELIAL CELLS;

FIBROBLAST GROWTH FACTOR 2; LENTIVIRUS VECTOR; LUCIFERASE; MICRORNA 15A; VASCULOTROPIN;

3' UNTRANSLATED REGION; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTIANGIOGENIC ACTIVITY; ARTICLE; CAPILLARY DENSITY; CELL DIFFERENTIATION; CELL SPECIFICITY; CONTROLLED STUDY; DRUG MECHANISM; DRUG TARGETING; GENE FUNCTION; GENE OVEREXPRESSION; GROWTH INHIBITION; HINDLIMB; HUMAN; HUMAN CELL; IMMUNOASSAY; LEG BLOOD FLOW; LIMB ISCHEMIA; MIGRATION INHIBITION; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN FUNCTION; REAL TIME POLYMERASE CHAIN REACTION; REPORTER GENE; TRANSGENE; UMBILICAL VEIN ENDOTHELIAL CELL; VASCULAR ENDOTHELIUM;

3' UNTRANSLATED REGIONS; ANIMALS; BASE SEQUENCE; DNA PRIMERS; FIBROBLAST GROWTH FACTOR 2; FLUORESCENT ANTIBODY TECHNIQUE; HINDLIMB; ISCHEMIA; MICE; MICE, INBRED C57BL; MICE, TRANSGENIC; MICRORNAS; NEOVASCULARIZATION, PATHOLOGIC; REAL-TIME POLYMERASE CHAIN REACTION; VASCULAR ENDOTHELIAL GROWTH FACTOR A;

EID: 84864553202     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M112.364414     Document Type: Article

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