Quercetin and EGCG exhibit chemopreventive effects in cholangiocarcinoma cells via suppression of JAK/STAT signaling pathway

Phytotherapy Research

Volumn 28, Issue 6, 2014, Pages 841-848

  Senggunprai, Laddawan ^a   Kukongviriyapan, Veerapol ^a   Prawan, Auemduan ^a   Kukongviriyapan, Upa ^a  

^a KHON KAEN UNIVERSITY   (Thailand)

Author keywords

chemopreventive; cholangiocarcinoma; EGCG; JAK STAT; phytochemical; quercetin

Indexed keywords

EPIGALLOCATECHIN GALLATE; GAMMA INTERFERON; INDUCIBLE NITRIC OXIDE SYNTHASE; INTERCELLULAR ADHESION MOLECULE 1; INTERLEUKIN 6; JANUS KINASE; JANUS KINASE 1; JANUS KINASE 2; QUERCETIN; STAT PROTEIN; STAT1 PROTEIN; STAT3 PROTEIN;

ANTINEOPLASTIC ACTIVITY; ANTIPROLIFERATIVE ACTIVITY; ARTICLE; BILE DUCT CARCINOMA; CANCER INHIBITION; CELL VIABILITY; CHEMOPROPHYLAXIS; CHOLANGIOCARCINOMA CELL LINE; CONCENTRATION RESPONSE; CONTROLLED STUDY; DRUG EFFECT; DRUG MECHANISM; ENZYME INHIBITION; ENZYME REPRESSION; HUMAN; HUMAN CELL; INTRACELLULAR SIGNALING; MIGRATION INHIBITION; PROTEIN EXPRESSION; PROTEIN PHOSPHORYLATION; UPREGULATION;

CHEMOPREVENTIVE; CHOLANGIOCARCINOMA; EGCG; JAK/STAT; PHYTOCHEMICAL; QUERCETIN;

BILE DUCT NEOPLASMS; BILE DUCTS, INTRAHEPATIC; CATECHIN; CELL LINE, TUMOR; CHOLANGIOCARCINOMA; HUMANS; INTERCELLULAR ADHESION MOLECULE-1; INTERFERON-GAMMA; INTERLEUKIN-6; JANUS KINASE 1; JANUS KINASE 2; NITRIC OXIDE SYNTHASE TYPE II; PHOSPHORYLATION; QUERCETIN; SIGNAL TRANSDUCTION; STAT1 TRANSCRIPTION FACTOR; STAT3 TRANSCRIPTION FACTOR; STAT5 TRANSCRIPTION FACTOR; TUMOR SUPPRESSOR PROTEINS;

EID: 84902299676     PISSN: 0951418X     EISSN: 10991573     Source Type: Journal    
DOI: 10.1002/ptr.5061     Document Type: Article

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