메뉴 건너뛰기




Volumn 13, Issue 48, 2007, Pages 6478-6491

JAK-STAT pathway in carcinogenesis: Is it relevant to cholangiocarcinoma progression?

Author keywords

Cholangiocarcinorna; Cytokine receptors; Interleukin 6; Janus tyrosine Kinases; Prolactin; Receptor tyrosine kinases; Signal Transducers and Activators of Transcription

Indexed keywords

CYTOKINE; CYTOKINE RECEPTOR; ERYTHROPOIETIN; ESTROGEN; GROWTH FACTOR; GROWTH HORMONE; INTERLEUKIN 6; JANUS KINASE; JANUS KINASE 1; JANUS KINASE 2; JANUS KINASE 3; LEPTIN; PROLACTIN; PROSTAGLANDIN E RECEPTOR; STAT PROTEIN; STAT1 PROTEIN; STAT2 PROTEIN; STAT3 PROTEIN; STAT4 PROTEIN; STAT5A PROTEIN; STAT5B PROTEIN; STAT6 PROTEIN; SUPPRESSOR OF CYTOKINE SIGNALING 1; SUPPRESSOR OF CYTOKINE SIGNALING 3;

EID: 38349063045     PISSN: 10079327     EISSN: None     Source Type: Journal    
DOI: 10.3748/wjg.13.6478     Document Type: Article
Times cited : (30)

References (183)
  • 1
    • 23244449296 scopus 로고    scopus 로고
    • Hebenstreit D, Horejs-Hoeck J, Duschl A. JAK/STAT-dependent gene regulation by cytokines. Drug News Perspect 2005; 18: 243-249
    • Hebenstreit D, Horejs-Hoeck J, Duschl A. JAK/STAT-dependent gene regulation by cytokines. Drug News Perspect 2005; 18: 243-249
  • 2
    • 11244335567 scopus 로고    scopus 로고
    • Cholangiocarcinoma: Molecular targeting strategies for chemoprevention and therapy
    • Sirica AE. Cholangiocarcinoma: molecular targeting strategies for chemoprevention and therapy. Hepatology 2005; 41: 5-15
    • (2005) Hepatology , vol.41 , pp. 5-15
    • Sirica, A.E.1
  • 3
    • 33746126998 scopus 로고    scopus 로고
    • Chronic bile duct injury associated with fibrotic matrix microenvironment provokes cholangiocarcinoma in p53-deficient mice
    • Farazi PA, Zeisberg M, Glickman J, Zhang Y, Kalluri R, DePinho RA. Chronic bile duct injury associated with fibrotic matrix microenvironment provokes cholangiocarcinoma in p53-deficient mice. Cancer Res 2006; 66: 6622-6627
    • (2006) Cancer Res , vol.66 , pp. 6622-6627
    • Farazi, P.A.1    Zeisberg, M.2    Glickman, J.3    Zhang, Y.4    Kalluri, R.5    DePinho, R.A.6
  • 4
    • 33745712699 scopus 로고    scopus 로고
    • Nervous and Neuroendocrine regulation of the pathophysiology of cholestasis and of biliary carcinogenesis
    • Marzioni M, Fava G, Benedetti A. Nervous and Neuroendocrine regulation of the pathophysiology of cholestasis and of biliary carcinogenesis. World J Gastroenterol 2006; 12: 3471-3480
    • (2006) World J Gastroenterol , vol.12 , pp. 3471-3480
    • Marzioni, M.1    Fava, G.2    Benedetti, A.3
  • 5
    • 0034234736 scopus 로고    scopus 로고
    • Growth control of human biliary epithelial cells by interleukin 6, hepatocyte growth factor, transforming growth factor beta1, and activin A: Comparison of a cholangiocarcinoma cell line with primary cultures of non-neoplastic biliary epithelial cells
    • Yokomuro S, Tsuji H, Lunz JG 3rd, Sakamoto T, Ezure T, Murase N, Demetris AJ. Growth control of human biliary epithelial cells by interleukin 6, hepatocyte growth factor, transforming growth factor beta1, and activin A: comparison of a cholangiocarcinoma cell line with primary cultures of non-neoplastic biliary epithelial cells. Hepatology 2000; 32: 26-35
    • (2000) Hepatology , vol.32 , pp. 26-35
    • Yokomuro, S.1    Tsuji, H.2    Lunz 3rd, J.G.3    Sakamoto, T.4    Ezure, T.5    Murase, N.6    Demetris, A.J.7
  • 7
    • 33244488736 scopus 로고    scopus 로고
    • Long isoform of prolactin receptor predominates in rat intrahepatic bile ducts and further increases under obstructive cholestasis
    • Bogorad RL, Ostroukhova TY, Orlova AN, Rubtsov PM, Smirnova OV. Long isoform of prolactin receptor predominates in rat intrahepatic bile ducts and further increases under obstructive cholestasis. J Endocrinol 2006; 188: 345-354
    • (2006) J Endocrinol , vol.188 , pp. 345-354
    • Bogorad, R.L.1    Ostroukhova, T.Y.2    Orlova, A.N.3    Rubtsov, P.M.4    Smirnova, O.V.5
  • 8
    • 0034125486 scopus 로고    scopus 로고
    • A new level of hormonal signal transduction: Primary nuclear action of protein and peptide hormones
    • Smirnova OV. A new level of hormonal signal transduction: primary nuclear action of protein and peptide hormones. Membr Cell Biol 2000; 13: 245-261
    • (2000) Membr Cell Biol , vol.13 , pp. 245-261
    • Smirnova, O.V.1
  • 10
    • 31444440292 scopus 로고    scopus 로고
    • Nuclear EGFR signalling network in cancers: Linking EGFR pathway to cell cycle progression, nitric oxide pathway and patient survival
    • Lo HW, Hung MC. Nuclear EGFR signalling network in cancers: linking EGFR pathway to cell cycle progression, nitric oxide pathway and patient survival. Br J Cancer 2006; 94: 184-188
    • (2006) Br J Cancer , vol.94 , pp. 184-188
    • Lo, H.W.1    Hung, M.C.2
  • 11
    • 29144462020 scopus 로고    scopus 로고
    • Growth hormone activity in mitochondria depends on GH receptor Box 1 and involves caveolar pathway targeting
    • Perret-Vivancos C, Abbate A, Ardail D, Raccurt M, Usson Y, Lobie PE, Morel G. Growth hormone activity in mitochondria depends on GH receptor Box 1 and involves caveolar pathway targeting. Exp Cell Res 2006; 312: 215-232
    • (2006) Exp Cell Res , vol.312 , pp. 215-232
    • Perret-Vivancos, C.1    Abbate, A.2    Ardail, D.3    Raccurt, M.4    Usson, Y.5    Lobie, P.E.6    Morel, G.7
  • 13
    • 0034657958 scopus 로고    scopus 로고
    • Roles of STAT3 defined by tissue-specific gene targeting
    • Akira S. Roles of STAT3 defined by tissue-specific gene targeting. Oncogene 2000; 19: 2607-2611
    • (2000) Oncogene , vol.19 , pp. 2607-2611
    • Akira, S.1
  • 14
    • 0037124102 scopus 로고    scopus 로고
    • Autocrine-mediated activation of STAT3 correlates with cell proliferation in breast carcinoma lines
    • Li L, Shaw PE. Autocrine-mediated activation of STAT3 correlates with cell proliferation in breast carcinoma lines. J Biol Chem 2002; 277: 17397-17405
    • (2002) J Biol Chem , vol.277 , pp. 17397-17405
    • Li, L.1    Shaw, P.E.2
  • 16
    • 32944463507 scopus 로고    scopus 로고
    • Cytokines, STATs and liver disease
    • Gao B. Cytokines, STATs and liver disease. Cell Mol Immunol 2005; 2: 92-100
    • (2005) Cell Mol Immunol , vol.2 , pp. 92-100
    • Gao, B.1
  • 17
    • 32144453842 scopus 로고    scopus 로고
    • Valentino L, Pierre J. JAK/STAT signal transduction: regulators and implication in hematological malignancies. Biochem Pharmacol 2006; 71: 713-721
    • Valentino L, Pierre J. JAK/STAT signal transduction: regulators and implication in hematological malignancies. Biochem Pharmacol 2006; 71: 713-721
  • 18
    • 0035667071 scopus 로고    scopus 로고
    • The central role of SOCS-3 in integrating the neuro-immunoendocrine interface
    • Auernhammer CJ, Melmed S. The central role of SOCS-3 in integrating the neuro-immunoendocrine interface. J Clin Invest 2001; 108: 1735-1740
    • (2001) J Clin Invest , vol.108 , pp. 1735-1740
    • Auernhammer, C.J.1    Melmed, S.2
  • 20
    • 24344480077 scopus 로고    scopus 로고
    • Interleukin-6 plays a crucial role in the hepatic expression of SOCS3 during acute inflammatory processes in vivo
    • Yang XP, Schaper F, Teubner A, Lammert F, Heinrich PC, Matern S, Siewert E. Interleukin-6 plays a crucial role in the hepatic expression of SOCS3 during acute inflammatory processes in vivo. J Hepatol 2005; 43: 704-710
    • (2005) J Hepatol , vol.43 , pp. 704-710
    • Yang, X.P.1    Schaper, F.2    Teubner, A.3    Lammert, F.4    Heinrich, P.C.5    Matern, S.6    Siewert, E.7
  • 21
    • 14644415484 scopus 로고    scopus 로고
    • Signal transducer and activator of transcription (STAT) signalling and T-cell lymphomas
    • Mitchell TJ, John S. Signal transducer and activator of transcription (STAT) signalling and T-cell lymphomas. Immunology 2005; 114: 301-312
    • (2005) Immunology , vol.114 , pp. 301-312
    • Mitchell, T.J.1    John, S.2
  • 23
    • 0033546315 scopus 로고    scopus 로고
    • ErbB receptor-induced activation of stat transcription factors is mediated by Src tyrosine kinases
    • Olayioye MA, Beuvink I, Horsch K, Daly JM, Hynes NE. ErbB receptor-induced activation of stat transcription factors is mediated by Src tyrosine kinases. J Biol Chem 1999; 274: 17209-17218
    • (1999) J Biol Chem , vol.274 , pp. 17209-17218
    • Olayioye, M.A.1    Beuvink, I.2    Horsch, K.3    Daly, J.M.4    Hynes, N.E.5
  • 25
    • 0035910507 scopus 로고    scopus 로고
    • Constitutive activation of JAK-STAT3 signaling by BRCA1 in human prostate cancer cells
    • Gao B, Shen X, Kunos G, Meng Q, Goldberg ID, Rosen EM, Fan S. Constitutive activation of JAK-STAT3 signaling by BRCA1 in human prostate cancer cells. FEBS Lett 2001; 488: 179-184
    • (2001) FEBS Lett , vol.488 , pp. 179-184
    • Gao, B.1    Shen, X.2    Kunos, G.3    Meng, Q.4    Goldberg, I.D.5    Rosen, E.M.6    Fan, S.7
  • 29
    • 1042302005 scopus 로고    scopus 로고
    • The STATs of cancer - new molecular targets come of age
    • Yu H, Jove R. The STATs of cancer - new molecular targets come of age. Nat Rev Cancer 2004; 4: 97-105
    • (2004) Nat Rev Cancer , vol.4 , pp. 97-105
    • Yu, H.1    Jove, R.2
  • 34
    • 24944563712 scopus 로고    scopus 로고
    • Autocrine prolactin as a promotor of mammary tumour growth
    • Manhes C, Goffin V, Kelly PA, Touraine P. Autocrine prolactin as a promotor of mammary tumour growth. J Dairy Res 2005; 72 Spec No: 58-65
    • (2005) J Dairy Res , Issue.72 SPEC , pp. 58-65
    • Manhes, C.1    Goffin, V.2    Kelly, P.A.3    Touraine, P.4
  • 35
    • 33746514504 scopus 로고    scopus 로고
    • Hyperprolactinaemia as an adverse effect in regulatory and clinical toxicology: Role in breast and prostate cancer
    • Harvey PW, Everett DJ, Springall CJ. Hyperprolactinaemia as an adverse effect in regulatory and clinical toxicology: role in breast and prostate cancer. Hum Exp Toxicol 2006; 25: 395-404
    • (2006) Hum Exp Toxicol , vol.25 , pp. 395-404
    • Harvey, P.W.1    Everett, D.J.2    Springall, C.J.3
  • 36
    • 34248190678 scopus 로고    scopus 로고
    • A prospective study of plasma prolactin concentrations and risk of premenopausal and postmenopausal breast cancer
    • Tworoger SS, Eliassen AH, Sluss P, Hankinson SE. A prospective study of plasma prolactin concentrations and risk of premenopausal and postmenopausal breast cancer. J Clin Oncol 2007; 25: 1482-1488
    • (2007) J Clin Oncol , vol.25 , pp. 1482-1488
    • Tworoger, S.S.1    Eliassen, A.H.2    Sluss, P.3    Hankinson, S.E.4
  • 37
    • 0026767794 scopus 로고
    • High frequency of mammary adenocarcinomas in metallothionein promoter-human growth hormone transgenic mice created from two different strains of mice
    • Tornell J, Carlsson B, Pohjanen P, Wennbo H, Rymo L, Isaksson O. High frequency of mammary adenocarcinomas in metallothionein promoter-human growth hormone transgenic mice created from two different strains of mice. J Steroid Biochem Mol Biol 1992; 43: 237-242
    • (1992) J Steroid Biochem Mol Biol , vol.43 , pp. 237-242
    • Tornell, J.1    Carlsson, B.2    Pohjanen, P.3    Wennbo, H.4    Rymo, L.5    Isaksson, O.6
  • 38
    • 1542329061 scopus 로고    scopus 로고
    • Endogenous human prolactin and not exogenous human prolactin induces estrogen receptor alpha and prolactin receptor expression and increases estrogen responsiveness in breast cancer cells
    • Gutzman JH, Miller KK, Schuler LA. Endogenous human prolactin and not exogenous human prolactin induces estrogen receptor alpha and prolactin receptor expression and increases estrogen responsiveness in breast cancer cells. J Steroid Biochem Mol Biol 2004; 88: 69-77
    • (2004) J Steroid Biochem Mol Biol , vol.88 , pp. 69-77
    • Gutzman, J.H.1    Miller, K.K.2    Schuler, L.A.3
  • 39
    • 18744404217 scopus 로고    scopus 로고
    • High stromal and epithelial human gh gene expression is associated with proliferative disorders of the mammary gland
    • Raccurt M, Lobie PE, Moudilou E, Garcia-Caballero T, Frappart L, Morel G, Mertard HC. High stromal and epithelial human gh gene expression is associated with proliferative disorders of the mammary gland. J Endocrinol 2002; 175: 307-318
    • (2002) J Endocrinol , vol.175 , pp. 307-318
    • Raccurt, M.1    Lobie, P.E.2    Moudilou, E.3    Garcia-Caballero, T.4    Frappart, L.5    Morel, G.6    Mertard, H.C.7
  • 44
    • 13444263403 scopus 로고    scopus 로고
    • Stat5 promotes homotypic adhesion and inhibits invasive characteristics of human breast cancer cells
    • Sultan AS, Xie J, LeBaron MJ, Ealley EL, Nevalainen MT, Rui H. Stat5 promotes homotypic adhesion and inhibits invasive characteristics of human breast cancer cells. Oncogene 2005; 24: 746-760
    • (2005) Oncogene , vol.24 , pp. 746-760
    • Sultan, A.S.1    Xie, J.2    LeBaron, M.J.3    Ealley, E.L.4    Nevalainen, M.T.5    Rui, H.6
  • 45
    • 32944469616 scopus 로고    scopus 로고
    • Defining the role of prolactin as an invasion suppressor hormone in breast cancer cells
    • Nouhi Z, Chughtai N, Hartley S, Cocolakis E, Lebrun JJ, Ali S. Defining the role of prolactin as an invasion suppressor hormone in breast cancer cells. Cancer Res 2006; 66: 1824-1832
    • (2006) Cancer Res , vol.66 , pp. 1824-1832
    • Nouhi, Z.1    Chughtai, N.2    Hartley, S.3    Cocolakis, E.4    Lebrun, J.J.5    Ali, S.6
  • 47
    • 0032460226 scopus 로고    scopus 로고
    • Prolactin (PRL) and its receptor: Actions, signal transduction pathways and phenotypes observed in PRL receptor knockout mice
    • Bole-Feysot C, Goffin V, Edery M, Binart N, Kelly PA. Prolactin (PRL) and its receptor: actions, signal transduction pathways and phenotypes observed in PRL receptor knockout mice. Endocr Rev 1998; 19: 225-268
    • (1998) Endocr Rev , vol.19 , pp. 225-268
    • Bole-Feysot, C.1    Goffin, V.2    Edery, M.3    Binart, N.4    Kelly, P.A.5
  • 48
    • 0036514607 scopus 로고    scopus 로고
    • Prolactin receptor diversity in humans: Novel isoforms suggest general principles
    • Horseman ND. Prolactin receptor diversity in humans: novel isoforms suggest general principles. Trends Endocrinol Metab 2002; 13: 47-48
    • (2002) Trends Endocrinol Metab , vol.13 , pp. 47-48
    • Horseman, N.D.1
  • 49
    • 0032111502 scopus 로고    scopus 로고
    • Effect of bromocriptin on prolactin receptor expression in liver cells after the common bile duct ligation
    • Orlova AN, Smirnova OV, Turovetskii VB, Smirnov AN. Effect of bromocriptin on prolactin receptor expression in liver cells after the common bile duct ligation. Biull Eksp Biol Med 1998; 126: 52-55
    • (1998) Biull Eksp Biol Med , vol.126 , pp. 52-55
    • Orlova, A.N.1    Smirnova, O.V.2    Turovetskii, V.B.3    Smirnov, A.N.4
  • 50
    • 0033129320 scopus 로고    scopus 로고
    • The role of prolactin in the functional regulation of liver cells after the common bile duct ligation
    • Orlova AN, Smirnov AN, Smirnova OV. The role of prolactin in the functional regulation of liver cells after the common bile duct ligation. Biull Eksp Biol Med 1999; 127: 573-575
    • (1999) Biull Eksp Biol Med , vol.127 , pp. 573-575
    • Orlova, A.N.1    Smirnov, A.N.2    Smirnova, O.V.3
  • 51
    • 0030621547 scopus 로고    scopus 로고
    • The prolactin/growth hormone receptor family: Structure/function relationships
    • Goffin V, Kelly PA. The prolactin/growth hormone receptor family: structure/function relationships. J Mammary Gland Biol Neoplasia 1997; 2: 7-17
    • (1997) J Mammary Gland Biol Neoplasia , vol.2 , pp. 7-17
    • Goffin, V.1    Kelly, P.A.2
  • 52
    • 0035209861 scopus 로고    scopus 로고
    • Cytokine-inducible SH2-containing protein suppresses PRL signaling by binding the PRL receptor
    • Dif F, Saunier E, Demeneix B, Kelly PA, Edery M. Cytokine-inducible SH2-containing protein suppresses PRL signaling by binding the PRL receptor. Endocrinology 2001; 142: 5286-5293
    • (2001) Endocrinology , vol.142 , pp. 5286-5293
    • Dif, F.1    Saunier, E.2    Demeneix, B.3    Kelly, P.A.4    Edery, M.5
  • 58
    • 33745206307 scopus 로고    scopus 로고
    • Overexpression of prolactin receptors during intrahepatic transplantation of RS1 rat cholangiocellular carcinoma cells
    • Ostroukhova TY, Kulikov AV, Rozenkrants AA, Smirnova OV. Overexpression of prolactin receptors during intrahepatic transplantation of RS1 rat cholangiocellular carcinoma cells. Bull Exp Biol Med 2006; 141: 364-367
    • (2006) Bull Exp Biol Med , vol.141 , pp. 364-367
    • Ostroukhova, T.Y.1    Kulikov, A.V.2    Rozenkrants, A.A.3    Smirnova, O.V.4
  • 59
    • 0038070057 scopus 로고    scopus 로고
    • Prolactin regulation of estrogen receptor expression
    • Frasor J, Gibori G. Prolactin regulation of estrogen receptor expression. Trends Endocrinol Metab 2003; 14: 118-123
    • (2003) Trends Endocrinol Metab , vol.14 , pp. 118-123
    • Frasor, J.1    Gibori, G.2
  • 60
    • 2542612109 scopus 로고    scopus 로고
    • Expression of prolactin receptor mRNA in oestrogen receptor positive breast cancers pre- and post-tamoxifen therapy
    • de Castillo B, Cawthorn S, Moppett J, Shere M, Norman M. Expression of prolactin receptor mRNA in oestrogen receptor positive breast cancers pre- and post-tamoxifen therapy. Eur J Surg Oncol 2004; 30: 515-519
    • (2004) Eur J Surg Oncol , vol.30 , pp. 515-519
    • de Castillo, B.1    Cawthorn, S.2    Moppett, J.3    Shere, M.4    Norman, M.5
  • 62
    • 33745856917 scopus 로고    scopus 로고
    • A novel estradiol/estrogen receptor alpha-dependent transcriptional mechanism controls expression of the human prolactin receptor
    • Dong J, Tsai-Morris CH, Dufau ML. A novel estradiol/estrogen receptor alpha-dependent transcriptional mechanism controls expression of the human prolactin receptor. J Biol Chem 2006; 281: 18825-18836
    • (2006) J Biol Chem , vol.281 , pp. 18825-18836
    • Dong, J.1    Tsai-Morris, C.H.2    Dufau, M.L.3
  • 63
    • 0034894006 scopus 로고    scopus 로고
    • Cross-talk between Stat5b and estrogen receptor-alpha and -beta in mammary epithelial cells
    • Bjornstrom L, Kilic E, Norman M, Parker MG, Sjoberg M. Cross-talk between Stat5b and estrogen receptor-alpha and -beta in mammary epithelial cells. J Mol Endocrinol 2001; 27: 93-106
    • (2001) J Mol Endocrinol , vol.27 , pp. 93-106
    • Bjornstrom, L.1    Kilic, E.2    Norman, M.3    Parker, M.G.4    Sjoberg, M.5
  • 64
    • 0034748380 scopus 로고    scopus 로고
    • Cross-talk between ERs and signal transducer and activator of transcription 5 is E2 dependent and involves two functionally separate mechanisms
    • Faulds MH, Pettersson K, Gustafsson JA, Haldosen LA. Cross-talk between ERs and signal transducer and activator of transcription 5 is E2 dependent and involves two functionally separate mechanisms. Mol Endocrinol 2001; 15: 1929-1940
    • (2001) Mol Endocrinol , vol.15 , pp. 1929-1940
    • Faulds, M.H.1    Pettersson, K.2    Gustafsson, J.A.3    Haldosen, L.A.4
  • 65
    • 1642505681 scopus 로고    scopus 로고
    • Estradiol represses prolactin-induced expression of Na+/taurocholate cotransporting polypeptide in liver cells through estrogen receptor-alpha and signal transducers and activators of transcription 5a
    • Cao J, Wood M. Liu Y, Hoffman T, Hyde J, Park-Sarge OK, Vore M. Estradiol represses prolactin-induced expression of Na+/taurocholate cotransporting polypeptide in liver cells through estrogen receptor-alpha and signal transducers and activators of transcription 5a. Endocrinology 2004; 145: 1739-1749
    • (2004) Endocrinology , vol.145 , pp. 1739-1749
    • Cao, J.1    Wood, M.2    Liu, Y.3    Hoffman, T.4    Hyde, J.5    Park-Sarge, O.K.6    Vore, M.7
  • 66
    • 4143120196 scopus 로고    scopus 로고
    • ERalpha and STAT5a cross-talk: Interaction through C-terminal portions of the proteins decreases STAT5a phosphorylation, nuclear translocation and DNA-binding
    • Wang Y. Cheng CH. ERalpha and STAT5a cross-talk: interaction through C-terminal portions of the proteins decreases STAT5a phosphorylation, nuclear translocation and DNA-binding. FEBS Lett 2004; 572: 238-244
    • (2004) FEBS Lett , vol.572 , pp. 238-244
    • Wang, Y.1    Cheng, C.H.2
  • 68
    • 14844332147 scopus 로고    scopus 로고
    • Cholangiocarcinoma: Risk factors, diagnosis and management
    • Acalovschi M. Cholangiocarcinoma: risk factors, diagnosis and management. Rom J Intern Med 2004; 42: 41-58
    • (2004) Rom J Intern Med , vol.42 , pp. 41-58
    • Acalovschi, M.1
  • 69
    • 33845528355 scopus 로고    scopus 로고
    • Prolactin modulates phosphorylation, signaling and trafficking of epidermal growth factor receptor in human T47D breast cancer cells
    • Huang Y, Li X, Jiang J, Frank SJ. Prolactin modulates phosphorylation, signaling and trafficking of epidermal growth factor receptor in human T47D breast cancer cells. Oncogene 2006; 25: 7565-7576
    • (2006) Oncogene , vol.25 , pp. 7565-7576
    • Huang, Y.1    Li, X.2    Jiang, J.3    Frank, S.J.4
  • 74
    • 33646886602 scopus 로고    scopus 로고
    • Sex steroids and leptin regulate 11beta-hydroxysteroid dehydrogenase I and P450 aromatase expressions in human preadipocytes: Sex specificities
    • Dieudonne MN, Sammari A, Dos Santos E, Leneveu MC, Giudicelli Y, Pecquery R. Sex steroids and leptin regulate 11beta-hydroxysteroid dehydrogenase I and P450 aromatase expressions in human preadipocytes: Sex specificities. J Steroid Biochem Mol Biol 2006; 99: 189-196
    • (2006) J Steroid Biochem Mol Biol , vol.99 , pp. 189-196
    • Dieudonne, M.N.1    Sammari, A.2    Dos Santos, E.3    Leneveu, M.C.4    Giudicelli, Y.5    Pecquery, R.6
  • 75
    • 30044434035 scopus 로고    scopus 로고
    • Intracellular signalling pathways activated by leptin
    • Fruhbeck G. Intracellular signalling pathways activated by leptin. Biochem J 2006; 393: 7-20
    • (2006) Biochem J , vol.393 , pp. 7-20
    • Fruhbeck, G.1
  • 79
    • 33847299599 scopus 로고    scopus 로고
    • Regulation of SOCS-3 expression by leptin and its co-localization with insulin receptor in rat skeletal muscle cells
    • Eguchi M, Gillis LC, Liu Y, Lyakhovsky N, Du M, McDermott JC, Sweeney G. Regulation of SOCS-3 expression by leptin and its co-localization with insulin receptor in rat skeletal muscle cells. Mol Cell Endocrinol 2007; 267: 38-45
    • (2007) Mol Cell Endocrinol , vol.267 , pp. 38-45
    • Eguchi, M.1    Gillis, L.C.2    Liu, Y.3    Lyakhovsky, N.4    Du, M.5    McDermott, J.C.6    Sweeney, G.7
  • 81
    • 0035926313 scopus 로고    scopus 로고
    • Leptin receptor long-form signalling in a human liver cell line
    • Briscoe CP, Hanif S, Arch JR, Tadayyon M. Leptin receptor long-form signalling in a human liver cell line. Cytokine 2001; 14: 225-229
    • (2001) Cytokine , vol.14 , pp. 225-229
    • Briscoe, C.P.1    Hanif, S.2    Arch, J.R.3    Tadayyon, M.4
  • 82
    • 9444223845 scopus 로고    scopus 로고
    • Leptin as a novel profibrogenic cytokine in hepatic stellate cells: Mitogenesis and inhibition of apoptosis mediated by extracellular regulated kinase (Erk) and Akt phosphorylation
    • Saxena NK, Titus MA, Ding X, Floyd J, Srinivasan S, Sitaraman SV, Anania FA. Leptin as a novel profibrogenic cytokine in hepatic stellate cells: mitogenesis and inhibition of apoptosis mediated by extracellular regulated kinase (Erk) and Akt phosphorylation. FASEB J 2004; 18: 1612-1614
    • (2004) FASEB J , vol.18 , pp. 1612-1614
    • Saxena, N.K.1    Titus, M.A.2    Ding, X.3    Floyd, J.4    Srinivasan, S.5    Sitaraman, S.V.6    Anania, F.A.7
  • 83
    • 19544378172 scopus 로고    scopus 로고
    • The roles of leptin and adiponectin: A novel paradigm in adipocytokine regulation of liver fibrosis and stellate cell biology
    • Ding X, Saxena NK, Lin S, Xu A, Srinivasan S, Anania FA. The roles of leptin and adiponectin: a novel paradigm in adipocytokine regulation of liver fibrosis and stellate cell biology. Am J Pathol 2005; 166: 1655-1669
    • (2005) Am J Pathol , vol.166 , pp. 1655-1669
    • Ding, X.1    Saxena, N.K.2    Lin, S.3    Xu, A.4    Srinivasan, S.5    Anania, F.A.6
  • 85
    • 23944504925 scopus 로고    scopus 로고
    • Partial cloning and localisation of leptin and its receptor in the one-humped camel (Camelus dromedarius)
    • Sayed-Ahmed A, Rudas P, Bartha T. Partial cloning and localisation of leptin and its receptor in the one-humped camel (Camelus dromedarius). Vet J 2005; 170: 264-267
    • (2005) Vet J , vol.170 , pp. 264-267
    • Sayed-Ahmed, A.1    Rudas, P.2    Bartha, T.3
  • 86
    • 0037300439 scopus 로고    scopus 로고
    • Pleiotropic functions of erythropoietin
    • Sasaki R. Pleiotropic functions of erythropoietin. Intern Med 2003; 42: 142-149
    • (2003) Intern Med , vol.42 , pp. 142-149
    • Sasaki, R.1
  • 87
    • 33845896785 scopus 로고    scopus 로고
    • Functional significance of erythropoietin receptor on tumor cells
    • Udupa KB. Functional significance of erythropoietin receptor on tumor cells. World J Gastroenterol 2006; 12: 7460-7462
    • (2006) World J Gastroenterol , vol.12 , pp. 7460-7462
    • Udupa, K.B.1
  • 88
    • 0027301403 scopus 로고
    • Erythropoietin as a mitogen for fetal liver stromal cells which support erythropoiesis
    • Ohneda O, Yanai N, Obinata M. Erythropoietin as a mitogen for fetal liver stromal cells which support erythropoiesis. Exp Cell Res 1993; 208: 327-331
    • (1993) Exp Cell Res , vol.208 , pp. 327-331
    • Ohneda, O.1    Yanai, N.2    Obinata, M.3
  • 91
    • 0022412177 scopus 로고
    • Erythropoietin production by macrophages in the regenerating liver
    • Naughton GK, Naughton BA, Gordon AS. Erythropoietin production by macrophages in the regenerating liver. J Surg Oncol 1985; 30: 184-197
    • (1985) J Surg Oncol , vol.30 , pp. 184-197
    • Naughton, G.K.1    Naughton, B.A.2    Gordon, A.S.3
  • 93
    • 3142514203 scopus 로고    scopus 로고
    • Erythropoietin/erythropoietin-receptor system as an angiogenic factor in chemically induced murine hepatic tumors
    • Nakamatsu K, Nishimura Y, Suzuki M, Kanamori S, Maenishi O, Yasuda Y. Erythropoietin/erythropoietin-receptor system as an angiogenic factor in chemically induced murine hepatic tumors. Int J Clin Oncol 2004; 9: 184-188
    • (2004) Int J Clin Oncol , vol.9 , pp. 184-188
    • Nakamatsu, K.1    Nishimura, Y.2    Suzuki, M.3    Kanamori, S.4    Maenishi, O.5    Yasuda, Y.6
  • 94
    • 9744250880 scopus 로고    scopus 로고
    • Selection, proliferation and differentiation of bone marrow-derived liver stem cells with a culture system containing cholestatic serum in vitro
    • Cai YF, Zhen ZJ, Min J, Fang TL, Chu ZH, Chen JS. Selection, proliferation and differentiation of bone marrow-derived liver stem cells with a culture system containing cholestatic serum in vitro. World J Gas troenterol 2004; 10: 3308-3312
    • (2004) World J Gas troenterol , vol.10 , pp. 3308-3312
    • Cai, Y.F.1    Zhen, Z.J.2    Min, J.3    Fang, T.L.4    Chu, Z.H.5    Chen, J.S.6
  • 95
    • 28544438991 scopus 로고    scopus 로고
    • Liver cancer: The role of stem cells
    • Alison MR, Lovell MJ. Liver cancer: the role of stem cells. Cell Prolif 2005; 38: 407-421
    • (2005) Cell Prolif , vol.38 , pp. 407-421
    • Alison, M.R.1    Lovell, M.J.2
  • 96
    • 33750798339 scopus 로고    scopus 로고
    • Hepatic progenitor cells in human liver tumor development
    • Libbrecht L. Hepatic progenitor cells in human liver tumor development. World J Gastroenterol 2006; 12: 6261-6265
    • (2006) World J Gastroenterol , vol.12 , pp. 6261-6265
    • Libbrecht, L.1
  • 97
    • 33745533559 scopus 로고    scopus 로고
    • Liver stem cells and their implication in hepatocellular and cholangiocarcinoma
    • Roskams T. Liver stem cells and their implication in hepatocellular and cholangiocarcinoma. Oncogene 2006; 25: 3818-3822
    • (2006) Oncogene , vol.25 , pp. 3818-3822
    • Roskams, T.1
  • 98
    • 0021724248 scopus 로고
    • Factors that regulate extrarenal erythropoietin production
    • Fried W, Barone-Varelas J, Morley C. Factors that regulate extrarenal erythropoietin production. Blood Cells 1984; 10: 287-304
    • (1984) Blood Cells , vol.10 , pp. 287-304
    • Fried, W.1    Barone-Varelas, J.2    Morley, C.3
  • 99
    • 0032566597 scopus 로고    scopus 로고
    • Estrogen-dependent production of erythropoietin in uterus and its implication in uterine angiogenesis
    • Yasuda Y, Masuda S, Chikuma M, Inoue K, Nagao M, Sasaki R. Estrogen-dependent production of erythropoietin in uterus and its implication in uterine angiogenesis. J Biol Chem 1998; 273: 25381-25387
    • (1998) J Biol Chem , vol.273 , pp. 25381-25387
    • Yasuda, Y.1    Masuda, S.2    Chikuma, M.3    Inoue, K.4    Nagao, M.5    Sasaki, R.6
  • 101
    • 0034658541 scopus 로고    scopus 로고
    • Roles of STAT3 in mediating the cell growth, differentiation and survival signals relayed through the IL-6 family of cytokine receptors
    • Hirano T, Ishihara K, Hibi M. Roles of STAT3 in mediating the cell growth, differentiation and survival signals relayed through the IL-6 family of cytokine receptors. Oncogene 2000; 19: 2548-2556
    • (2000) Oncogene , vol.19 , pp. 2548-2556
    • Hirano, T.1    Ishihara, K.2    Hibi, M.3
  • 102
    • 33947358052 scopus 로고    scopus 로고
    • Ishikawa H, Tsuyama N, Obata M, M Kawano M. Mitogenic signals initiated via interleukin-6 receptor complexes in cooperation with other transmembrane molecules in myelomas. J Clin Exp Hematop 2006; 46: 55-66
    • Ishikawa H, Tsuyama N, Obata M, M Kawano M. Mitogenic signals initiated via interleukin-6 receptor complexes in cooperation with other transmembrane molecules in myelomas. J Clin Exp Hematop 2006; 46: 55-66
  • 103
    • 0037422983 scopus 로고    scopus 로고
    • Effects of bile acids on biliary epithelial cells: Proliferation, cytotoxicity, and cytokine secretion
    • Lamireau T, Zoltowska M, Levy E, Yousef I, Rosenbaum J, Tuchweber B, Desmouliere A. Effects of bile acids on biliary epithelial cells: proliferation, cytotoxicity, and cytokine secretion. Life Sci 2003; 72: 1401-1411
    • (2003) Life Sci , vol.72 , pp. 1401-1411
    • Lamireau, T.1    Zoltowska, M.2    Levy, E.3    Yousef, I.4    Rosenbaum, J.5    Tuchweber, B.6    Desmouliere, A.7
  • 104
    • 33745698658 scopus 로고    scopus 로고
    • Biliary wound healing, ductular reactions, and IL-6/gp130 signaling in the development of liver disease
    • Demetris AJ, Lunz JG 3rd, Specht S, Nozaki I. Biliary wound healing, ductular reactions, and IL-6/gp130 signaling in the development of liver disease. World J Gastroenterol 2006; 12: 3512-3529
    • (2006) World J Gastroenterol , vol.12 , pp. 3512-3529
    • Demetris, A.J.1    Lunz 3rd, J.G.2    Specht, S.3    Nozaki, I.4
  • 108
    • 33746253022 scopus 로고    scopus 로고
    • Chronic bile duct obstruction induces changes in plasma and hepatic levels of cytokines and nitric oxide in the rat
    • Fernandez-Martinez E, Perez-Alvarez V, Tsutsumi V, Shibayama M, Muriel P. Chronic bile duct obstruction induces changes in plasma and hepatic levels of cytokines and nitric oxide in the rat. Exp Toxicol Pathol 2006; 58: 49-58
    • (2006) Exp Toxicol Pathol , vol.58 , pp. 49-58
    • Fernandez-Martinez, E.1    Perez-Alvarez, V.2    Tsutsumi, V.3    Shibayama, M.4    Muriel, P.5
  • 109
    • 33747677468 scopus 로고    scopus 로고
    • Modulation of Stat3 activation by the cytosolic phospholipase A2alpha and cyclooxygenase-2-controlled prostaglandin E2 signaling pathway
    • Han C, Demetris AJ, Stolz DB, Xu L, Lim K, Wu T. Modulation of Stat3 activation by the cytosolic phospholipase A2alpha and cyclooxygenase-2-controlled prostaglandin E2 signaling pathway. J Biol Chem 2006; 281: 24831-24846
    • (2006) J Biol Chem , vol.281 , pp. 24831-24846
    • Han, C.1    Demetris, A.J.2    Stolz, D.B.3    Xu, L.4    Lim, K.5    Wu, T.6
  • 110
    • 33746902024 scopus 로고    scopus 로고
    • Over-expression of interleukin-6 enhances cell survival and transformed cell growth in human malignant cholangiocytes
    • Meng F, Yamagiwa Y, Ueno Y, Patel T. Over-expression of interleukin-6 enhances cell survival and transformed cell growth in human malignant cholangiocytes. J Hepatol 2006; 44: 1055-1065
    • (2006) J Hepatol , vol.44 , pp. 1055-1065
    • Meng, F.1    Yamagiwa, Y.2    Ueno, Y.3    Patel, T.4
  • 111
    • 32944479992 scopus 로고    scopus 로고
    • Interleukin 6 upregulates myeloid cell leukemia-1 expression through a STAT3 pathway in cholangiocarcinoma cells
    • Isomoto H, Kobayashi S, Werneburg NW, Bronk SF, Guicciardi ME, Frank DA, Gores GJ. Interleukin 6 upregulates myeloid cell leukemia-1 expression through a STAT3 pathway in cholangiocarcinoma cells. Hepatology 2005; 42: 1329-1338
    • (2005) Hepatology , vol.42 , pp. 1329-1338
    • Isomoto, H.1    Kobayashi, S.2    Werneburg, N.W.3    Bronk, S.F.4    Guicciardi, M.E.5    Frank, D.A.6    Gores, G.J.7
  • 113
    • 0035853710 scopus 로고    scopus 로고
    • Co-operative effect of c-Src tyrosine kinase and Stat3 in activation of hepatocyte growth factor expression in mammary carcinoma cells
    • Hung W, Elliott B. Co-operative effect of c-Src tyrosine kinase and Stat3 in activation of hepatocyte growth factor expression in mammary carcinoma cells. J Biol Chem 2001; 276: 12395-12403
    • (2001) J Biol Chem , vol.276 , pp. 12395-12403
    • Hung, W.1    Elliott, B.2
  • 114
    • 1242317881 scopus 로고    scopus 로고
    • The human hepatocyte growth factor (HGF) gene is transcriptionally activated by leukemia inhibitory factor through the Stat binding element
    • Tomida M, Saito T. The human hepatocyte growth factor (HGF) gene is transcriptionally activated by leukemia inhibitory factor through the Stat binding element. Oncogene 2004; 23: 679-686
    • (2004) Oncogene , vol.23 , pp. 679-686
    • Tomida, M.1    Saito, T.2
  • 115
    • 1442300813 scopus 로고    scopus 로고
    • Has HGF met other partners? Met-independent epithelial morphogenesis induced by HGF focus on "Hepatocyte growth factor induces MDCK cell morphogenesis without causing loss of tight junction functional integrity
    • Devarajan P. Has HGF met other partners? Met-independent epithelial morphogenesis induced by HGF focus on "Hepatocyte growth factor induces MDCK cell morphogenesis without causing loss of tight junction functional integrity". Am J Physiol Cell Physiol 2004; 286: C475-C477
    • (2004) Am J Physiol Cell Physiol , vol.286
    • Devarajan, P.1
  • 116
    • 5444231787 scopus 로고    scopus 로고
    • Invasive growth: A genetic program
    • Gentile A, Comoglio PM. Invasive growth: a genetic program. Int J Dev Biol 2004; 48: 451-456
    • (2004) Int J Dev Biol , vol.48 , pp. 451-456
    • Gentile, A.1    Comoglio, P.M.2
  • 117
    • 24144443283 scopus 로고    scopus 로고
    • MET meet adaptors: Functional and structural implications in downstream signalling mediated by the Met receptor
    • Bolanos-Garcia VM. MET meet adaptors: functional and structural implications in downstream signalling mediated by the Met receptor. Mol Cell Biochem 2005; 276: 149-157
    • (2005) Mol Cell Biochem , vol.276 , pp. 149-157
    • Bolanos-Garcia, V.M.1
  • 118
    • 0033584725 scopus 로고    scopus 로고
    • STAT 1alpha/1beta, STAT 3 and STAT 5: Expression and association with c-MET and EGF-receptor in long-term cultures of human hepatocytes
    • Runge DM, Runge D, Foth H, Strom SC, Michalopoulos GK. STAT 1alpha/1beta, STAT 3 and STAT 5: expression and association with c-MET and EGF-receptor in long-term cultures of human hepatocytes. Biochem Biophys Res Commun 1999; 265: 376-381
    • (1999) Biochem Biophys Res Commun , vol.265 , pp. 376-381
    • Runge, D.M.1    Runge, D.2    Foth, H.3    Strom, S.C.4    Michalopoulos, G.K.5
  • 119
    • 0036238957 scopus 로고    scopus 로고
    • Hepatocyte growth factor stimulates proliferation of pancreatic beta-cells particularly in the presence of subphysiological glucose concentrations
    • Gahr S, Merger M, Bollheimer LC, Hammerschmied CG, Scholmerich J, Hugl SR. Hepatocyte growth factor stimulates proliferation of pancreatic beta-cells particularly in the presence of subphysiological glucose concentrations. J Mol Endocrinol 2002; 28: 99-110
    • (2002) J Mol Endocrinol , vol.28 , pp. 99-110
    • Gahr, S.1    Merger, M.2    Bollheimer, L.C.3    Hammerschmied, C.G.4    Scholmerich, J.5    Hugl, S.R.6
  • 121
    • 18144383511 scopus 로고    scopus 로고
    • The SPRY domain-containing SOCS box protein 1 (SSB-1) interacts with MET and enhances the hepatocyte growth factor-induced Erk-Elk-1-serum response element pathway
    • Wang D, Li Z, Messing EM, Wu G. The SPRY domain-containing SOCS box protein 1 (SSB-1) interacts with MET and enhances the hepatocyte growth factor-induced Erk-Elk-1-serum response element pathway. J Biol Chem 2005; 280: 16393-16401
    • (2005) J Biol Chem , vol.280 , pp. 16393-16401
    • Wang, D.1    Li, Z.2    Messing, E.M.3    Wu, G.4
  • 123
    • 0036322129 scopus 로고    scopus 로고
    • ERBB-2 overexpression and cyclooxygenase-2 up-regulation in human cholangiocarcinoma and risk conditions
    • Endo K, Yoon BI, Pairojkul C, Demetris AJ, Sirica AE. ERBB-2 overexpression and cyclooxygenase-2 up-regulation in human cholangiocarcinoma and risk conditions. Hepatology 2002; 36: 439-450
    • (2002) Hepatology , vol.36 , pp. 439-450
    • Endo, K.1    Yoon, B.I.2    Pairojkul, C.3    Demetris, A.J.4    Sirica, A.E.5
  • 124
    • 33847055836 scopus 로고    scopus 로고
    • Antinecrotic and antiapoptotic effects of hepatocyte growth factor on cholestatic hepatitis in a mouse model of bile-obstructive diseases
    • Li Z, Mizuno S, Nakamura T. Antinecrotic and antiapoptotic effects of hepatocyte growth factor on cholestatic hepatitis in a mouse model of bile-obstructive diseases. Am J Physiol Gastrointest Liver Physiol 2007; 292: G639-G646
    • (2007) Am J Physiol Gastrointest Liver Physiol , vol.292
    • Li, Z.1    Mizuno, S.2    Nakamura, T.3
  • 126
    • 33748508832 scopus 로고    scopus 로고
    • The clinical value of hepatocyte growth factor and its receptor-c-met for liver cancer patients with hepatectomy
    • Wu F, Wu L, Zheng S, Ding W, Teng L, Wang Z, Ma Z, Zhao W. The clinical value of hepatocyte growth factor and its receptor-c-met for liver cancer patients with hepatectomy. Dig Liver Dis 2006; 38: 490-497
    • (2006) Dig Liver Dis , vol.38 , pp. 490-497
    • Wu, F.1    Wu, L.2    Zheng, S.3    Ding, W.4    Teng, L.5    Wang, Z.6    Ma, Z.7    Zhao, W.8
  • 128
    • 33749037451 scopus 로고    scopus 로고
    • Augmented expression of hepatocytes growth factor activator inhibitor type 1 (HAI-1) in intrahepatic small bile ducts in primary biliary cirrhosis
    • Sasaki M, Ikeda H, Kataoka H, Nakanuma Y. Augmented expression of hepatocytes growth factor activator inhibitor type 1 (HAI-1) in intrahepatic small bile ducts in primary biliary cirrhosis. Virchows Arch 2006; 449: 462-471
    • (2006) Virchows Arch , vol.449 , pp. 462-471
    • Sasaki, M.1    Ikeda, H.2    Kataoka, H.3    Nakanuma, Y.4
  • 129
    • 0032951925 scopus 로고    scopus 로고
    • Overexpression of C-NEU and C-MET during rat liver cholangiocarcinogenesis: A link between biliary intestinal metaplasia and mucin-producing cholangiocarcinoma
    • Radaeva S, Ferreira-Gonzalez A, Sirica AE. Overexpression of C-NEU and C-MET during rat liver cholangiocarcinogenesis: A link between biliary intestinal metaplasia and mucin-producing cholangiocarcinoma. Hepatology 1999; 29: 1453-1462
    • (1999) Hepatology , vol.29 , pp. 1453-1462
    • Radaeva, S.1    Ferreira-Gonzalez, A.2    Sirica, A.E.3
  • 130
    • 21344438897 scopus 로고    scopus 로고
    • Amplification and overexpression of c-erbB-2, epidermal growth factor receptor, and c-met in biliary tract cancers
    • Nakazawa K, Dobashi Y, Suzuki S, Fujii H, Takeda Y, Ooi A. Amplification and overexpression of c-erbB-2, epidermal growth factor receptor, and c-met in biliary tract cancers. J Pathol 2005; 206: 356-365
    • (2005) J Pathol , vol.206 , pp. 356-365
    • Nakazawa, K.1    Dobashi, Y.2    Suzuki, S.3    Fujii, H.4    Takeda, Y.5    Ooi, A.6
  • 131
    • 33750287121 scopus 로고    scopus 로고
    • Involvement of c-Met/hepatocyte growth factor pathway in cholangiocarcinoma cell invasion and its therapeutic inhibition with small interfering RNA specific for c-Met
    • Leelawat K, Leelawat S, Tepaksorn P, Rattanasinganchan P, Leungchaweng A, Tohtong R, Sobhon P. Involvement of c-Met/hepatocyte growth factor pathway in cholangiocarcinoma cell invasion and its therapeutic inhibition with small interfering RNA specific for c-Met. J Surg Res 2006; 136: 78-84
    • (2006) J Surg Res , vol.136 , pp. 78-84
    • Leelawat, K.1    Leelawat, S.2    Tepaksorn, P.3    Rattanasinganchan, P.4    Leungchaweng, A.5    Tohtong, R.6    Sobhon, P.7
  • 132
    • 0344873744 scopus 로고    scopus 로고
    • Autocrine-mediated ErbB-2 kinase activation of STAT3 is required for growth factor independence of pancreatic cancer cell lines
    • DeArmond D, Brattain MG, Jessup JM, Kreisberg J, Malik S, Zhao S, Freeman JW. Autocrine-mediated ErbB-2 kinase activation of STAT3 is required for growth factor independence of pancreatic cancer cell lines. Oncogene 2003; 22: 7781-7795
    • (2003) Oncogene , vol.22 , pp. 7781-7795
    • DeArmond, D.1    Brattain, M.G.2    Jessup, J.M.3    Kreisberg, J.4    Malik, S.5    Zhao, S.6    Freeman, J.W.7
  • 134
    • 0035006109 scopus 로고    scopus 로고
    • Tyrosine-phosphorylated SOCS-3 inhibits STAT activation but binds to p120 RasGAP and activates Ras
    • Cacalano NA, Sanden D, Johnston JA. Tyrosine-phosphorylated SOCS-3 inhibits STAT activation but binds to p120 RasGAP and activates Ras. Nat Cell Biol 2001; 3: 460-465
    • (2001) Nat Cell Biol , vol.3 , pp. 460-465
    • Cacalano, N.A.1    Sanden, D.2    Johnston, J.A.3
  • 137
    • 33846467633 scopus 로고    scopus 로고
    • Epidermal growth factor receptor inhibition strategies in pancreatic cancer: Past, present and the future
    • Cohenuram M, Saif MW. Epidermal growth factor receptor inhibition strategies in pancreatic cancer: past, present and the future. JOP 2007; 8: 4-15
    • (2007) JOP , vol.8 , pp. 4-15
    • Cohenuram, M.1    Saif, M.W.2
  • 139
    • 0036623359 scopus 로고    scopus 로고
    • Gene amplification and mRNA and protein overexpression of c-erbB-2 (HER-2/neu) in human intrahepatic cholangiocarcinoma as detected by fluorescence in situ hybridization, in situ hybridization, and immunohistochemistry
    • Ukita Y, Kato M, Terada T. Gene amplification and mRNA and protein overexpression of c-erbB-2 (HER-2/neu) in human intrahepatic cholangiocarcinoma as detected by fluorescence in situ hybridization, in situ hybridization, and immunohistochemistry. J Hepatol 2002; 36: 780-785
    • (2002) J Hepatol , vol.36 , pp. 780-785
    • Ukita, Y.1    Kato, M.2    Terada, T.3
  • 141
    • 0028923388 scopus 로고
    • Cell proliferation and oncogene expression after bile duct ligation in the rat: Evidence of a specific growth effect on bile duct cells
    • Polimeno L, Azzarone A, Zeng QH, Panella C, Subbotin V, Carr B, Bouzahzah B, Francavilla A, Starzl TE. Cell proliferation and oncogene expression after bile duct ligation in the rat: evidence of a specific growth effect on bile duct cells. Hepatology 1995; 21: 1070-1078
    • (1995) Hepatology , vol.21 , pp. 1070-1078
    • Polimeno, L.1    Azzarone, A.2    Zeng, Q.H.3    Panella, C.4    Subbotin, V.5    Carr, B.6    Bouzahzah, B.7    Francavilla, A.8    Starzl, T.E.9
  • 142
    • 0034941321 scopus 로고    scopus 로고
    • Expression of oncogene products HER2/Neu and Ras and fibrosis-related growth factors bFGF, TGF-beta, and PDGF in bile from biliary malignancies and inflammatory disorders
    • Su WC, Shiesh SC, Liu HS, Chen CY, Chow NH, Lin XZ. Expression of oncogene products HER2/Neu and Ras and fibrosis-related growth factors bFGF, TGF-beta, and PDGF in bile from biliary malignancies and inflammatory disorders. Dig Dis Sci 2001; 46: 1387-1392
    • (2001) Dig Dis Sci , vol.46 , pp. 1387-1392
    • Su, W.C.1    Shiesh, S.C.2    Liu, H.S.3    Chen, C.Y.4    Chow, N.H.5    Lin, X.Z.6
  • 143
    • 3042818975 scopus 로고    scopus 로고
    • Thioacetamide-induced intestinal-type cholangiocarcinoma in rat: An animal model recapitulating the multi-stage progression of human cholangiocarcinoma
    • Yeh CN, Maitra A, Lee KF, Jan YY, Chen MF. Thioacetamide-induced intestinal-type cholangiocarcinoma in rat: an animal model recapitulating the multi-stage progression of human cholangiocarcinoma. Carcinogenesis 2004; 25: 631-636
    • (2004) Carcinogenesis , vol.25 , pp. 631-636
    • Yeh, C.N.1    Maitra, A.2    Lee, K.F.3    Jan, Y.Y.4    Chen, M.F.5
  • 144
    • 33748169241 scopus 로고    scopus 로고
    • Novel targeted approaches to treating biliary tract cancer: The dual epidermal growth factor receptor and ErbB-2 tyrosine kinase inhibitor NVP-AEE788 is more efficient than the epidermal growth factor receptor inhibitors gefitinib and erlotinib
    • Wiedmann M, Feisthammel J, Bluthner T, Tannapfel A, Kamenz T, Kluge A, Mossner J, Caca K. Novel targeted approaches to treating biliary tract cancer: the dual epidermal growth factor receptor and ErbB-2 tyrosine kinase inhibitor NVP-AEE788 is more efficient than the epidermal growth factor receptor inhibitors gefitinib and erlotinib. Anticancer Drugs 2006; 17: 783-795
    • (2006) Anticancer Drugs , vol.17 , pp. 783-795
    • Wiedmann, M.1    Feisthammel, J.2    Bluthner, T.3    Tannapfel, A.4    Kamenz, T.5    Kluge, A.6    Mossner, J.7    Caca, K.8
  • 145
    • 0026048419 scopus 로고
    • Functional antagonism between endogenous mouse growth hormone (GH) and a GH analog results in dwarf transgenic mice
    • Chen WY, White ME, Wagner TE, Kopchick JJ. Functional antagonism between endogenous mouse growth hormone (GH) and a GH analog results in dwarf transgenic mice. Endocrinology 1991; 129: 1402-1408
    • (1991) Endocrinology , vol.129 , pp. 1402-1408
    • Chen, W.Y.1    White, M.E.2    Wagner, T.E.3    Kopchick, J.J.4
  • 148
    • 0031613778 scopus 로고    scopus 로고
    • Induction of expression of prolactin receptors in cholangiocytes of male and female rats after ligation of the common bile duct
    • Smirnova OV, Petrashchuk OM, Smirnov AN. Induction of expression of prolactin receptors in cholangiocytes of male and female rats after ligation of the common bile duct. Biull Eksp Biol Med 1998; 125: 66-70
    • (1998) Biull Eksp Biol Med , vol.125 , pp. 66-70
    • Smirnova, O.V.1    Petrashchuk, O.M.2    Smirnov, A.N.3
  • 149
    • 0036727115 scopus 로고    scopus 로고
    • Neuregulin-1 activates the JAK-STAT pathway and regulates lung epithelial cell proliferation
    • Liu J, Kern JA. Neuregulin-1 activates the JAK-STAT pathway and regulates lung epithelial cell proliferation. Am J Respir Cell Mol Biol 2002; 27: 306-313
    • (2002) Am J Respir Cell Mol Biol , vol.27 , pp. 306-313
    • Liu, J.1    Kern, J.A.2
  • 150
    • 33645792636 scopus 로고    scopus 로고
    • IL-4 induced MUC4 enhancement in respiratory epithelial cells in vitro is mediated through JAK-3 selective signaling
    • Damera G, Xia B, Sachdev GP. IL-4 induced MUC4 enhancement in respiratory epithelial cells in vitro is mediated through JAK-3 selective signaling. Respir Res 2006; 7: 39
    • (2006) Respir Res , vol.7 , pp. 39
    • Damera, G.1    Xia, B.2    Sachdev, G.P.3
  • 151
    • 34347207060 scopus 로고    scopus 로고
    • SFK-STAT pathway: An alternative and important way to malignancies
    • Hayakawa F, Naoe T. SFK-STAT pathway: an alternative and important way to malignancies. Ann N Y Acad Sci 2006; 1086: 213-222
    • (2006) Ann N Y Acad Sci , vol.1086 , pp. 213-222
    • Hayakawa, F.1    Naoe, T.2
  • 152
    • 28044445899 scopus 로고    scopus 로고
    • Role of immature myeloid cells in mechanisms of immune evasion in cancer
    • Kusmartsev S, Gabrilovich DI. Role of immature myeloid cells in mechanisms of immune evasion in cancer. Cancer Immunol Immunother 2006; 55: 237-245
    • (2006) Cancer Immunol Immunother , vol.55 , pp. 237-245
    • Kusmartsev, S.1    Gabrilovich, D.I.2
  • 153
    • 27144433826 scopus 로고    scopus 로고
    • Methylation silencing of SOCS-3 promotes cell growth and migration by enhancing JAK/STAT and FAK signalings in human hepatocellular carcinoma
    • Niwa Y, Kanda H, Shikauchi Y, Saiura A, Matsubara K, Kitagawa T, Yamamoto J, Kubo T, Yoshikawa H. Methylation silencing of SOCS-3 promotes cell growth and migration by enhancing JAK/STAT and FAK signalings in human hepatocellular carcinoma. Oncogene 2005; 24: 6406-6417
    • (2005) Oncogene , vol.24 , pp. 6406-6417
    • Niwa, Y.1    Kanda, H.2    Shikauchi, Y.3    Saiura, A.4    Matsubara, K.5    Kitagawa, T.6    Yamamoto, J.7    Kubo, T.8    Yoshikawa, H.9
  • 155
    • 0033976059 scopus 로고    scopus 로고
    • The Jak-Stat pathway in normal and perturbed hematopoiesis
    • Ward AC, Touw I, Yoshimura A. The Jak-Stat pathway in normal and perturbed hematopoiesis. Blood 2000; 95: 19-29
    • (2000) Blood , vol.95 , pp. 19-29
    • Ward, A.C.1    Touw, I.2    Yoshimura, A.3
  • 156
    • 0042854950 scopus 로고    scopus 로고
    • Prolactin regulation of Bcl-2 family members: Increased expression of bcl-xL but not mcl-1 or bad in Nb2-T cells
    • Kochendoerfer SK, Krishnan N, Buckley DJ, Buckley AR. Prolactin regulation of Bcl-2 family members: increased expression of bcl-xL but not mcl-1 or bad in Nb2-T cells. J Endocrinol 2003; 178: 265-273
    • (2003) J Endocrinol , vol.178 , pp. 265-273
    • Kochendoerfer, S.K.1    Krishnan, N.2    Buckley, D.J.3    Buckley, A.R.4
  • 158
    • 33645797100 scopus 로고    scopus 로고
    • Substance P stimulates cyclooxygenase-2 and prostaglandin E2 expression through JAK-STAT activation in human colonic epithelial cells
    • Koon HW, Zhao D, Zhan Y, Rhee SH, Moyer MP, Pothoulakis C. Substance P stimulates cyclooxygenase-2 and prostaglandin E2 expression through JAK-STAT activation in human colonic epithelial cells. J Immunol 2006; 176: 5050-5059
    • (2006) J Immunol , vol.176 , pp. 5050-5059
    • Koon, H.W.1    Zhao, D.2    Zhan, Y.3    Rhee, S.H.4    Moyer, M.P.5    Pothoulakis, C.6
  • 160
    • 0033611585 scopus 로고    scopus 로고
    • Interleukin-6 dependent induction of the cyclin dependent kinase inhibitor p21WAF1/CIP1 is lost during progression of human malignant melanoma
    • Florenes VA, Lu C, Bhattacharya N, Rak J, Sheehan C, Slingerland JM, Kerbel RS. Interleukin-6 dependent induction of the cyclin dependent kinase inhibitor p21WAF1/CIP1 is lost during progression of human malignant melanoma. Oncogene 1999; 18: 1023-1032
    • (1999) Oncogene , vol.18 , pp. 1023-1032
    • Florenes, V.A.1    Lu, C.2    Bhattacharya, N.3    Rak, J.4    Sheehan, C.5    Slingerland, J.M.6    Kerbel, R.S.7
  • 162
    • 0034612529 scopus 로고    scopus 로고
    • STAT3-mediated differentiation and survival and of myeloid cells in response to granulocyte colony-stimulating factor: Tole for the cyclin-dependent kinase inhibitor p27(Kip1)
    • de Koning JP, Soede-Bobok AA, Ward AC, Schelen AM, Antonissen C, van Leeuwen D, Lowenberg B, Touw IP. STAT3-mediated differentiation and survival and of myeloid cells in response to granulocyte colony-stimulating factor: Tole for the cyclin-dependent kinase inhibitor p27(Kip1). Oncogene 2000; 19: 3290-3298
    • (2000) Oncogene , vol.19 , pp. 3290-3298
    • de Koning, J.P.1    Soede-Bobok, A.A.2    Ward, A.C.3    Schelen, A.M.4    Antonissen, C.5    van Leeuwen, D.6    Lowenberg, B.7    Touw, I.P.8
  • 163
    • 0034279419 scopus 로고    scopus 로고
    • Erythropoietin: Multiple physiological functions and regulation of biosynthesis
    • Sasaki R, Masuda S, Nagao M. Erythropoietin: multiple physiological functions and regulation of biosynthesis. Biosci Biotechnol Biochem 2000; 64: 1775-1793
    • (2000) Biosci Biotechnol Biochem , vol.64 , pp. 1775-1793
    • Sasaki, R.1    Masuda, S.2    Nagao, M.3
  • 164
    • 0035794196 scopus 로고    scopus 로고
    • A stat-responsive element in the promoter of the episialin/MUC1 gene is involved in its overexpression in carcinoma cells
    • Gaemers IC, Vos HL, Volders HH, van der Valk SW, Hilkens J. A stat-responsive element in the promoter of the episialin/MUC1 gene is involved in its overexpression in carcinoma cells. J Biol Chem 2001; 276: 6191-6199
    • (2001) J Biol Chem , vol.276 , pp. 6191-6199
    • Gaemers, I.C.1    Vos, H.L.2    Volders, H.H.3    van der Valk, S.W.4    Hilkens, J.5
  • 165
    • 0035903173 scopus 로고    scopus 로고
    • Characterization of human mucin gene MUC4 promoter: Importance of growth factors and proinflammatory cytokines for its regulation in pancreatic cancer cells
    • Perrais M, Pigny P, Ducourouble MP, Petitprez D, Porchet N, Aubert JP, Van Seuningen I. Characterization of human mucin gene MUC4 promoter: importance of growth factors and proinflammatory cytokines for its regulation in pancreatic cancer cells. J Biol Chem 2001; 276: 30923-30933
    • (2001) J Biol Chem , vol.276 , pp. 30923-30933
    • Perrais, M.1    Pigny, P.2    Ducourouble, M.P.3    Petitprez, D.4    Porchet, N.5    Aubert, J.P.6    Van Seuningen, I.7
  • 166
    • 0036614697 scopus 로고    scopus 로고
    • Grasl-Kraupp B, Schausberger E, Hufnagl K, Gerner C, Low-Baselli A, Rossmanith W, Parzefall W, Schulte-Hermann R. A novel mechanism for mitogenic signaling via pro-transforming growth factor alpha within hepatocyte nuclei. Hepatology 2002; 35: 1372-1380
    • Grasl-Kraupp B, Schausberger E, Hufnagl K, Gerner C, Low-Baselli A, Rossmanith W, Parzefall W, Schulte-Hermann R. A novel mechanism for mitogenic signaling via pro-transforming growth factor alpha within hepatocyte nuclei. Hepatology 2002; 35: 1372-1380
  • 168
    • 11244280137 scopus 로고    scopus 로고
    • Novel prognostic value of nuclear epidermal growth factor receptor in breast cancer
    • Lo HW, Xia W, Wei Y, Ali-Seyed M, Huang SF, Hung MC. Novel prognostic value of nuclear epidermal growth factor receptor in breast cancer. Cancer Res 2005; 65: 338-348
    • (2005) Cancer Res , vol.65 , pp. 338-348
    • HW, L.1    Xia, W.2    Wei, Y.3    Ali-Seyed, M.4    Huang, S.F.5    Hung, M.C.6
  • 169
    • 33645217263 scopus 로고    scopus 로고
    • EGFR signaling pathway in breast cancers: From traditional signal transduction to direct nuclear translocalization
    • Lo HW, Hsu SC, Hung MC. EGFR signaling pathway in breast cancers: from traditional signal transduction to direct nuclear translocalization. Breast Cancer Res Treat 2006; 95: 211-218
    • (2006) Breast Cancer Res Treat , vol.95 , pp. 211-218
    • HW, L.1    Hsu, S.C.2    Hung, M.C.3
  • 170
    • 0037076393 scopus 로고    scopus 로고
    • The intranuclear prolactin/cyclophilin B complex as a transcriptional inducer
    • Rycyzyn MA, Clevenger CV. The intranuclear prolactin/cyclophilin B complex as a transcriptional inducer. Proc Natl Acad Sci USA 2002; 99: 6790-6795
    • (2002) Proc Natl Acad Sci USA , vol.99 , pp. 6790-6795
    • Rycyzyn, M.A.1    Clevenger, C.V.2
  • 171
    • 0038724938 scopus 로고    scopus 로고
    • Nuclear localization and function of polypeptide ligands and their receptors: A new paradigm for hormone specificity within the mammary gland?
    • Clevenger CV. Nuclear localization and function of polypeptide ligands and their receptors: a new paradigm for hormone specificity within the mammary gland? Breast Cancer Res 2003; 5: 181-187
    • (2003) Breast Cancer Res , vol.5 , pp. 181-187
    • Clevenger, C.V.1
  • 172
    • 0037458560 scopus 로고    scopus 로고
    • The growth hormone-binding protein is a location-dependent cytokine receptor transcriptional enhancer
    • Graichen R, Sandstedt J, Goh EL, Isaksson OG, Tornell J, Lobie PE. The growth hormone-binding protein is a location-dependent cytokine receptor transcriptional enhancer. J Biol Chem 2003; 278: 6346-6354
    • (2003) J Biol Chem , vol.278 , pp. 6346-6354
    • Graichen, R.1    Sandstedt, J.2    Goh, E.L.3    Isaksson, O.G.4    Tornell, J.5    Lobie, P.E.6
  • 175
    • 23844442173 scopus 로고    scopus 로고
    • Quantitative determination of nuclear and cytoplasmic epidermal growth factor receptor expression in oropharyngeal squamous cell cancer by using automated quantitative analysis
    • Psyrri A, Yu Z, Weinberger PM, Sasaki C, Haffty B, Camp R, Rimm D, Burtness BA. Quantitative determination of nuclear and cytoplasmic epidermal growth factor receptor expression in oropharyngeal squamous cell cancer by using automated quantitative analysis. Clin Cancer Res 2005; 11: 5856-5862
    • (2005) Clin Cancer Res , vol.11 , pp. 5856-5862
    • Psyrri, A.1    Yu, Z.2    Weinberger, P.M.3    Sasaki, C.4    Haffty, B.5    Camp, R.6    Rimm, D.7    Burtness, B.A.8
  • 176
    • 33746561717 scopus 로고    scopus 로고
    • Nuclear-cytoplasmic transport of EGFR involves receptor endocytosis, importin beta1 and CRM1
    • Lo HW, Ali-Seyed M, Wu Y, Bartholomeusz G, Hsu SC, Hung MC. Nuclear-cytoplasmic transport of EGFR involves receptor endocytosis, importin beta1 and CRM1. J Cell Biochem 2006; 98: 1570-1583
    • (2006) J Cell Biochem , vol.98 , pp. 1570-1583
    • HW, L.1    Ali-Seyed, M.2    Wu, Y.3    Bartholomeusz, G.4    Hsu, S.C.5    Hung, M.C.6
  • 178
    • 33748288086 scopus 로고    scopus 로고
    • Muraoka-Cook RS, Sandahl M, Husted C, Hunter D, Miraglia L, Feng SM, Elenius K, Earp HS 3rd. The intracellular domain of ErbB4 induces differentiation of mammary epithelial cells. Mol Biol Cell 2006; 17: 4118-4129
    • Muraoka-Cook RS, Sandahl M, Husted C, Hunter D, Miraglia L, Feng SM, Elenius K, Earp HS 3rd. The intracellular domain of ErbB4 induces differentiation of mammary epithelial cells. Mol Biol Cell 2006; 17: 4118-4129
  • 180
    • 33746531672 scopus 로고    scopus 로고
    • Nuclear Jak2 and transcription factor NF1-C2: A novel mechanism of prolactin signaling in mammary epithelial cells
    • Nilsson J, Bjursell G, Kannius-Janson M. Nuclear Jak2 and transcription factor NF1-C2: a novel mechanism of prolactin signaling in mammary epithelial cells. Mol Cell Biol 2006; 26: 5663-5674
    • (2006) Mol Cell Biol , vol.26 , pp. 5663-5674
    • Nilsson, J.1    Bjursell, G.2    Kannius-Janson, M.3
  • 181
    • 21244487829 scopus 로고    scopus 로고
    • Presenilin-dependent gamma-secretase processing regulates multiple ERBB4/HER4 activities
    • Vidal GA, Naresh A, Marrero L, Jones FE. Presenilin-dependent gamma-secretase processing regulates multiple ERBB4/HER4 activities. J Biol Chem 2005; 280: 19777-19783
    • (2005) J Biol Chem , vol.280 , pp. 19777-19783
    • Vidal, G.A.1    Naresh, A.2    Marrero, L.3    Jones, F.E.4
  • 182
    • 8444243682 scopus 로고    scopus 로고
    • The ERBB4/HER4 receptor tyrosine kinase regulates gene expression by functioning as a STAT5A nuclear chaperone
    • Williams CC, Allison JG, Vidal GA, Burow ME, Beckman BS, Marrero L, Jones FE. The ERBB4/HER4 receptor tyrosine kinase regulates gene expression by functioning as a STAT5A nuclear chaperone. J Cell Biol 2004; 167: 469-478
    • (2004) J Cell Biol , vol.167 , pp. 469-478
    • Williams, C.C.1    Allison, J.G.2    Vidal, G.A.3    Burow, M.E.4    Beckman, B.S.5    Marrero, L.6    Jones, F.E.7


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.