Systemic inflammatory response elicited by superantigen destabilizes T regulatory cells, rendering them ineffective during toxic shock syndrome

Journal of Immunology

Volumn 193, Issue 6, 2014, Pages 2919-2930

  Tilahun, Ashenafi Y ^a   Chowdhary, Vaidehi R ^b   David, Chella S ^a   Rajagopalan, Govindarajan ^a,b  

^a MAYO GRADUATE SCHOOL   (United States)

^b MAYO CLINIC   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ANTIBODY; GAMMA INTERFERON; GLUCOCORTICOID; HLA DR3 ANTIGEN; INTERLEUKIN 17; INTERLEUKIN 2; INTERLEUKIN 2 ANTIBODY; SUPERANTIGEN; TUMOR NECROSIS FACTOR RECEPTOR; UNCLASSIFIED DRUG; ANTIGEN ANTIBODY COMPLEX; ENTEROTOXIN; ENTEROTOXIN B, STAPHYLOCOCCAL; GLUCOCORTICOID INDUCED TUMOR NECROSIS FACTOR RECEPTOR; HLA DR ANTIGEN; TNFRSF18 PROTEIN, MOUSE;

ADOPTIVE TRANSFER; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CELL EXPANSION; CONTROLLED STUDY; EX VIVO STUDY; IMMUNOREGULATION; MOUSE; NONHUMAN; PRIORITY JOURNAL; REGULATORY T LYMPHOCYTE; SYSTEMIC INFLAMMATORY RESPONSE SYNDROME; T LYMPHOCYTE ACTIVATION; TOXIC SHOCK SYNDROME; UPREGULATION; ANIMAL; ANTIGEN ANTIBODY COMPLEX; BIOSYNTHESIS; BLOOD; GENETICS; IMMUNOLOGY; LYMPHOCYTE ACTIVATION; METHICILLIN RESISTANT STAPHYLOCOCCUS AUREUS; MICROBIOLOGY; PATHOGENICITY; PHARMACOLOGY; SEPTIC SHOCK; STAPHYLOCOCCUS INFECTION; TRANSGENIC MOUSE; TRANSPLANTATION;

ADOPTIVE TRANSFER; ANIMALS; ANTIBODIES; ANTIGEN-ANTIBODY COMPLEX; ENTEROTOXINS; GLUCOCORTICOID-INDUCED TNFR-RELATED PROTEIN; GLUCOCORTICOIDS; HLA-DR ALPHA-CHAINS; HLA-DR BETA-CHAINS; HLA-DR3 ANTIGEN; INTERFERON-GAMMA; INTERLEUKIN-17; INTERLEUKIN-2; LYMPHOCYTE ACTIVATION; METHICILLIN-RESISTANT STAPHYLOCOCCUS AUREUS; MICE; MICE, TRANSGENIC; RECEPTORS, TUMOR NECROSIS FACTOR; SHOCK, SEPTIC; STAPHYLOCOCCAL INFECTIONS; SUPERANTIGENS; T-LYMPHOCYTES, REGULATORY; UP-REGULATION;

EID: 84921688756     PISSN: 00221767     EISSN: 15506606     Source Type: Journal    
DOI: 10.4049/jimmunol.1400980     Document Type: Article

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