-
1
-
-
84874189388
-
Caspase-11 protects against bacteria that escape the vacuole
-
Aachoui Y, Leaf IA, Hagar JA, Fontana MF, Campos CG, Zak DE, Tan MH, Cotter PA, Vance RE, Aderem A, Miao EA. Caspase-11 protects against bacteria that escape the vacuole. Science 339: 975–978, 2013.
-
(2013)
Science
, vol.339
, pp. 975-978
-
-
Aachoui, Y.1
Leaf, I.A.2
Hagar, J.A.3
Fontana, M.F.4
Campos, C.G.5
Zak6
Tan, D.7
Cotter, P.A.8
Vance, R.E.9
Aderem, A.10
Miao, E.A.11
-
2
-
-
34548125305
-
Interleukins 1beta and 6 but not transforming growth factor-beta are essential for the differentiation of interleukin 17-producing human T helper cells
-
Acosta-Rodriguez EV, Napolitani G, Lanzavecchia A, Sallusto F. Interleukins 1beta and 6 but not transforming growth factor-beta are essential for the differentiation of interleukin 17-producing human T helper cells. Nat Immunol 8: 942-949, 2007.
-
(2007)
Nat Immunol
, vol.8
, pp. 942-949
-
-
Acosta-Rodriguez, E.V.1
Napolitani, G.2
Lanzavecchia, A.3
Sallusto, F.4
-
3
-
-
84863263746
-
Analysis of NLRP3 in the development of allergic airway disease in mice
-
Allen IC, Jania CM, Wilson JE, Tekeppe EM, Hua X, Brickey WJ, Kwan M, Koller BH, Tilley SL, Ting JP. Analysis of NLRP3 in the development of allergic airway disease in mice. J Immunol 188: 2884-2893, 2012.
-
(2012)
J Immunol
, vol.188
, pp. 2884-2893
-
-
Allen, I.C.1
Jania, C.M.2
Wilson, J.E.3
Tekeppe, E.M.4
Hua5
Brickey, X.W.6
Kwan, M.7
Koller, B.H.8
Tilley, S.L.9
Ting, J.P.10
-
4
-
-
77952303410
-
The NLRP3 inflammasome functions as a negative regulator of tumorigenesis during colitis-associated cancer
-
Allen IC, TeKippe EM, Woodford RM, Uronis JM, Holl EK, Rogers AB, Herfarth HH, Jobin C, Ting JP. The NLRP3 inflammasome functions as a negative regulator of tumorigenesis during colitis-associated cancer. J Exp Med 207: 1045-1056, 2010.
-
(2010)
J Exp Med
, vol.207
, pp. 1045-1056
-
-
Allen, I.C.1
Tekippe, E.M.2
Woodford, R.M.3
Uronis, J.M.4
Holl, E.K.5
Rogers, A.B.6
Herfarth, H.H.7
Jobin8
Ting, C.9
-
5
-
-
84861460062
-
NLRP12 suppresses colon inflammation and tumorigenesis through the negative regulation of noncanonical NF-kappaB signaling
-
Allen IC, Wilson JE, Schneider M, Lich JD, Roberts RA, Arthur JC, Woodford RM, Davis BK, Uronis JM, Herfarth HH, Jobin C, Rogers AB, Ting JP. NLRP12 suppresses colon inflammation and tumorigenesis through the negative regulation of noncanonical NF-kappaB signaling. Immunity 36: 742-754, 2012.
-
(2012)
Immunity
, vol.36
, pp. 742-754
-
-
Allen, I.C.1
Wilson, J.E.2
Schneider, M.3
Lich4
Roberts, J.5
Arthur, J.C.6
Woodford, R.M.7
Davis, B.K.8
Uronis, J.M.9
Herfarth, H.H.10
Jobin, C.11
Rogers, A.B.12
Ting, J.P.13
-
6
-
-
20444373390
-
MyD88-deficient mice develop severe intestinal inflammation in dextran sodium sulfate colitis
-
Araki A, Kanai T, Ishikura T, Makita S, Uraushihara K, Iiyama R, Totsuka T, Takeda K, Akira S, Watanabe M. MyD88-deficient mice develop severe intestinal inflammation in dextran sodium sulfate colitis. J Gastroenterol 40: 16–23, 2005.
-
(2005)
J Gastroenterol
, vol.40
, pp. 16-23
-
-
Araki, A.1
Kanai, T.2
Ishikura, T.3
Makita, S.4
Uraushihara, K.5
Iiyama, R.6
Totsuka, T.7
Takeda, K.8
Akira, S.9
Watanabe, M.10
-
7
-
-
66349089266
-
IL-1 acts directly on CD4 T cells to enhance their antigen-driven expansion and differentiation
-
Ben-Sasson SZ, Hu-Li J, Quiel J, Cauchetaux S, Ratner M, Shapira I, Dinarello CA, Paul WE. IL-1 acts directly on CD4 T cells to enhance their antigen-driven expansion and differentiation. Proc Natl Acad Sci USA 106: 7119-7124, 2009.
-
(2009)
Proc Natl Acad Sci USA
, vol.106
, pp. 7119-7124
-
-
Ben-Sasson, S.Z.1
Hu-Li, J.2
Quiel, J.3
Cauchetaux, S.4
Ratner, M.5
Shapira, I.6
Dinarello, C.A.7
Paul, W.E.8
-
8
-
-
84895502154
-
Non-redundantproperties of IL-1alpha and IL-1beta during acute colon inflammation in mice
-
Bersudsky M, Luski L, Fishman D, White RM, Ziv-Sokolovskaya N, Dotan S, Rider P, Kaplanov I, Aychek T, Dinarello CA, Apte RN, Voronov E. Non-redundant properties of IL-1alpha and IL-1beta during acute colon inflammation in mice. Gut 63: 598-609, 2014.
-
(2014)
Gut
, vol.63
, pp. 598-609
-
-
Bersudsky, M.1
Luski, L.2
Fishman, D.3
White, R.M.4
Ziv-Sokolovskaya, N.5
Dotan, S.6
Rider, P.7
Kaplanov, I.8
Aychek, T.9
Dinarello, C.A.10
Apte, R.N.11
Voronov, E.12
-
9
-
-
84867333450
-
Caspase-11 increases susceptibility to Salmonella infection in the absence of caspase-1
-
Broz P, Ruby T, Belhocine K, Bouley DM, Kayagaki N, Dixit VM, Monack DM. Caspase-11 increases susceptibility to Salmonella infection in the absence of caspase-1. Nature 490: 288-291, 2012.
-
(2012)
Nature
, vol.490
, pp. 288-291
-
-
Broz, P.1
Ruby, T.2
Belhocine, K.3
Bouley, D.M.4
Kayagaki, N.5
Dixit, V.M.6
Monack, D.M.7
-
10
-
-
79959540809
-
A functional role for Nlrp6 in intestinal inflammation and tumorigenesis
-
Chen GY, Liu M, Wang F, Bertin J, Nunez G. A functional role for Nlrp6 in intestinal inflammation and tumorigenesis. J Immunol 186: 7187-7194, 2011.
-
(2011)
J Immunol
, vol.186
, pp. 7187-7194
-
-
Chen, G.Y.1
Liu, M.2
Wang, F.3
Bertin, J.4
Nunez, G.5
-
11
-
-
64049089798
-
Critical regulation of early Th17 cell differentiation by interleukin-1 signaling
-
Chung Y, Chang SH, Martinez GJ, Yang XO, Nurieva R, Kang HS, Ma L, Watowich SS, Jetten AM, Tian Q, Dong C. Critical regulation of early Th17 cell differentiation by interleukin-1 signaling. Immunity 30: 576-587, 2009.
-
(2009)
Immunity
, vol.30
, pp. 576-587
-
-
Chung, Y.1
Chang, S.H.2
Martinez, G.J.3
Yang, X.O.4
Nurieva, R.5
Kang, H.S.6
Ma, L.7
Watowich, S.S.8
Jetten, A.M.9
Tian, Q.10
Dong, C.11
-
12
-
-
84866362664
-
IL-1beta mediates chronic intestinal inflammation by promoting the accumulation of IL-17A secreting innate lymphoid cells and CD4(+) Th17 cells
-
Coccia M, Harrison OJ, Schiering C, Asquith MJ, Becher B, Powrie F, Maloy KJ. IL-1beta mediates chronic intestinal inflammation by promoting the accumulation of IL-17A secreting innate lymphoid cells and CD4(+) Th17 cells. J Exp Med 209: 1595-1609, 2012.
-
(2012)
J Exp Med
, vol.209
, pp. 1595-1609
-
-
Coccia, M.1
Harrison, O.J.2
Schiering, C.3
Asquith, M.J.4
Becher, B.5
Powrie, F.6
Maloy, K.J.7
-
13
-
-
0035283318
-
Pro-inflammatory programmed cell death
-
Cookson BT, Brennan MA. Pro-inflammatory programmed cell death. Trends Microbiol 9: 113-114, 2001.
-
(2001)
Trends Microbiol
, vol.9
, pp. 113-114
-
-
Cookson, B.T.1
Brennan, M.A.2
-
14
-
-
0032251330
-
The relationship of chronic mucin secretion to airway disease in normal and CFTR-deficient mice
-
Cressman VL, Hicks EM, Funkhouser WK, Backlund DC, Koller BH. The relationship of chronic mucin secretion to airway disease in normal and CFTR-deficient mice. Am J Respir Cell Mol Biol 19: 853-866, 1998.
-
(1998)
Am J Respir Cell Mol Biol
, vol.19
, pp. 853-866
-
-
Cressman, V.L.1
Hicks, E.M.2
Funkhouser, W.K.3
Backlund, D.C.4
Koller, B.H.5
-
15
-
-
84921462183
-
Emerging significance of NLRs in inflammatory bowel disease
-
Davis BK, Philipson C, Hontecillas R, Eden K, Bassaganya-Riera J, Allen IC. Emerging significance of NLRs in inflammatory bowel disease. Inflamm Bowel Dis 20: 2412-2432, 2014.
-
(2014)
Inflamm Bowel Dis
, vol.20
, pp. 2412-2432
-
-
Davis, B.K.1
Philipson, C.2
Hontecillas, R.3
Eden, K.4
Bassaganya-Riera, J.5
Allen, I.C.6
-
16
-
-
84908190489
-
Caspase-11 is expressed in the colonic mucosa and protects against dextran sodium sulfate-induced colitis
-
Demon D, Kuchmiy A, Fossoul A, Zhu Q, Kanneganti TD, Lamkanfi M. Caspase-11 is expressed in the colonic mucosa and protects against dextran sodium sulfate-induced colitis. Mucosal Immunol 7: 1504, 2014.
-
(2014)
Mucosal Immunol
, vol.7
, pp. 1504
-
-
Demon, D.1
Kuchmiy, A.2
Fossoul, A.3
Zhu, Q.4
Kanneganti, T.D.5
Lamkanfi, M.6
-
17
-
-
77949965210
-
Control of intestinal homeostasis, colitis, and colitis-associated colorectal cancer by the inflammatory caspases
-
Dupaul-Chicoine J, Yeretssian G, Doiron K, Bergstrom KS, McIntire CR, LeBlanc PM, Meunier C, Turbide C, Gros P, Beauchemin N, Vallance BA, Saleh M. Control of intestinal homeostasis, colitis, and colitis-associated colorectal cancer by the inflammatory caspases. Immunity 32: 367-378, 2010.
-
(2010)
Immunity
, vol.32
, pp. 367-378
-
-
Dupaul-Chicoine, J.1
Yeretssian, G.2
Doiron, K.3
Bergstrom4
McIntire, K.5
Leblanc, P.M.6
Meunier, C.7
Turbide, C.8
Gros, P.9
Beauchemin, N.10
Vallance, B.A.11
Saleh, M.12
-
18
-
-
79957576718
-
NLRP6 inflammasome regulates colonic microbial ecology and risk for colitis
-
Elinav E, Strowig T, Kau AL, Henao-Mejia J, Thaiss CA, Booth CJ, Peaper DR, Bertin J, Eisenbarth SC, Gordon JI, Flavell RA. NLRP6 inflammasome regulates colonic microbial ecology and risk for colitis. Cell 145: 745-757, 2011.
-
(2011)
Cell
, vol.145
, pp. 745-757
-
-
Elinav, E.1
Strowig, T.2
Kau, A.L.3
Henao-Mejia, J.4
Thaiss, C.A.5
Booth, C.J.6
Peaper, D.R.7
Bertin, J.8
Eisenbarth, S.C.9
Gordon, J.I.10
Flavell, R.A.11
-
19
-
-
34548031870
-
The pyroptosome: A supramolecular assembly of ASC dimers mediating inflammatory cell death via caspase-1 activation
-
Fernandes-Alnemri T, Wu J, Yu JW, Datta P, Miller B, Jankowski W, Rosenberg S, Zhang J, Alnemri ES. The pyroptosome: A supramolecular assembly of ASC dimers mediating inflammatory cell death via caspase-1 activation. Cell Death Differ 14: 1590-1604, 2007.
-
(2007)
Cell Death Differ
, vol.14
, pp. 1590-1604
-
-
Fernandes-Alnemri, T.1
Wu, J.2
Yu, J.W.3
Datta, P.4
Miller, B.5
Jankowski, W.6
Rosenberg, S.7
Zhang, J.8
Alnemri, E.S.9
-
20
-
-
33749576792
-
Caspase-1-dependent pore formation during pyroptosis leads to osmotic lysis of infected host macrophages
-
Fink SL, Cookson BT. Caspase-1-dependent pore formation during pyroptosis leads to osmotic lysis of infected host macrophages. Cell Microbiol 8: 1812-1825, 2006.
-
(2006)
Cell Microbiol
, vol.8
, pp. 1812-1825
-
-
Fink, S.L.1
Cookson, B.T.2
-
21
-
-
34848866958
-
Pyroptosis and host cell death responses during Salmonella infection
-
Fink SL, Cookson BT. Pyroptosis and host cell death responses during Salmonella infection. Cell Microbiol 9: 2562-2570, 2007.
-
(2007)
Cell Microbiol
, vol.9
, pp. 2562-2570
-
-
Fink, S.L.1
Cookson, B.T.2
-
22
-
-
4043088499
-
IKKbeta links inflammation and tumorigenesis in a mouse model of colitis-associated cancer
-
Greten FR, Eckmann L, Greten TF, Park JM, Li ZW, Egan LJ, Kagnoff MF, Karin M. IKKbeta links inflammation and tumorigenesis in a mouse model of colitis-associated cancer. Cell 118: 285-296, 2004.
-
(2004)
Cell
, vol.118
, pp. 285-296
-
-
Greten, F.R.1
Eckmann, L.2
Greten, T.F.3
Park, J.M.4
Li, Z.W.5
Egan, L.J.6
Kagnoff, M.F.7
Karin, M.8
-
23
-
-
84867241369
-
Toll or interleukin-1 receptor (TIR) domain-containing adaptor inducing interferon-beta (TRIF)-mediated caspase-11 protease production integrates Toll-like receptor 4 (TLR4) protein- and Nlrp3 inflammasome-mediated host defense against enteropathogens
-
Gurung P, Malireddi RK, Anand PK, Demon D, Vande Walle L, Liu Z, Vogel P, Lamkanfi M, Kanneganti TD. Toll or interleukin-1 receptor (TIR) domain-containing adaptor inducing interferon-beta (TRIF)-mediated caspase-11 protease production integrates Toll-like receptor 4 (TLR4) protein- and Nlrp3 inflammasome-mediated host defense against enteropathogens. J Biol Chem 287: 34474–34483, 2012.
-
(2012)
J Biol Chem
, vol.287
, pp. 34474-34483
-
-
Gurung, P.1
Malireddi, R.K.2
Anand, P.K.3
Demon, D.4
Vande Walle, L.5
Liu, Z.6
Vogel, P.7
Lamkanfi, M.8
Kanneganti, T.D.9
-
24
-
-
84883790050
-
Activates caspase-11: Implications in TLR4-independent endotoxic shock
-
Hagar JA, Powell DA, Aachoui Y, Ernst RK, Miao EA. Cytoplasmic LPS activates caspase-11: Implications in TLR4-independent endotoxic shock. Science 341: 1250–1253, 2013.
-
(2013)
Science
, vol.341
, pp. 1250-1253
-
-
Hagar, J.A.1
Powell, D.A.2
Aachoui, Y.3
Ernst, R.K.4
Miao, E.A.5
Cytoplasmic, L.6
-
25
-
-
79955846705
-
NLRP3 inflammasome plays a key role in the regulation of intestinal homeostasis
-
Hirota SA, Ng J, Lueng A, Khajah M, Parhar K, Li Y, Lam V, Potentier MS, Ng K, Bawa M, McCafferty DM, Rioux KP, Ghosh S, Xavier RJ, Colgan SP, Tschopp J, Muruve D, MacDonald JA, Beck PL. NLRP3 inflammasome plays a key role in the regulation of intestinal homeostasis. Inflamm Bowel Dis 17: 1359–1372, 2011.
-
(2011)
Inflamm Bowel Dis
, vol.17
, pp. 1359-1372
-
-
Hirota, S.A.1
Ng, J.2
Lueng, A.3
Khajah, M.4
Parhar, K.5
Li, Y.6
Lam, V.7
Potentier, M.S.8
Ng, K.9
Bawa, M.10
McCafferty, D.M.11
Rioux, K.P.12
Ghosh, S.13
Xavier14
Colgan, R.15
Tschopp, J.16
Muruve, D.17
Macdonald, J.A.18
Beck, P.L.19
-
26
-
-
84925022855
-
Generation of bone marrow and fetal liver chimeric mice
-
Holl EK. Generation of bone marrow and fetal liver chimeric mice. Methods Mol Biol 1032: 315–321, 2013.
-
(2013)
Methods Mol Biol
, vol.1032
, pp. 315-321
-
-
Holl, E.K.1
-
27
-
-
78650735879
-
Inflammation-induced tumorigenesis in the colon is regulated by caspase-1 and NLRC4
-
Hu B, Elinav E, Huber S, Booth CJ, Strowig T, Jin C, Eisenbarth SC, Flavell RA. Inflammation-induced tumorigenesis in the colon is regulated by caspase-1 and NLRC4. Proc Natl Acad Sci USA 107: 21635–21640, 2010.
-
(2010)
Proc Natl Acad Sci USA
, vol.107
, pp. 21635-21640
-
-
Hu, B.1
Elinav, E.2
Huber, S.3
Booth, C.J.4
Strowig, T.5
Jin, C.6
Eisenbarth, S.C.7
Flavell, R.A.8
-
28
-
-
84878971321
-
Microbiota-induced activation of epithelial IL-6 signaling links inflammasome-driven inflammation with transmissible cancer
-
Hu B, Elinav E, Huber S, Strowig T, Hao L, Hafemann A, Jin C, Wunderlich C, Wunderlich T, Eisenbarth SC, Flavell RA. Microbiota-induced activation of epithelial IL-6 signaling links inflammasome-driven inflammation with transmissible cancer. Proc Natl Acad Sci USA 110: 9862–9867, 2013.
-
(2013)
Proc Natl Acad Sci USA
, vol.110
, pp. 9862-9867
-
-
Hu, B.1
Elinav, E.2
Huber, S.3
Strowig, T.4
Hao, L.5
Hafemann, A.6
Jin, C.7
Wunderlich, C.8
Wunderlich, T.9
Eisenbarth, S.C.10
Flavell, R.A.11
-
29
-
-
0034192466
-
Dual role of caspase-11 in mediating activation of caspase-1 and caspase-3 under pathological conditions
-
Kang SJ, Wang S, Hara H, Peterson EP, Namura S, Amin-Hanjani S, Huang Z, Srinivasan A, Tomaselli KJ, Thornberry NA, Moskowitz MA, Yuan J. Dual role of caspase-11 in mediating activation of caspase-1 and caspase-3 under pathological conditions. J Cell Biol 149: 613–622, 2000.
-
(2000)
J Cell Biol
, vol.149
, pp. 613-622
-
-
Kang, S.J.1
Wang, S.2
Hara, H.3
Peterson, E.P.4
Namura, S.5
Amin-Hanjani, S.6
Huang, Z.7
Srinivasan, A.8
Tomaselli, K.J.9
Thornberry, N.A.10
Moskowitz, M.A.11
Yuan, J.12
-
30
-
-
80455176839
-
Non-canonical inflammasome activation targets caspase-11
-
Kayagaki N, Warming S, Lamkanfi M, Vande Walle L, Louie S, Dong J, Newton K, Qu Y, Liu J, Heldens S, Zhang J, Lee WP, Roose-Girma M, Dixit VM. Non-canonical inflammasome activation targets caspase-11. Nature 479: 117–121, 2011.
-
(2011)
Nature
, vol.479
, pp. 117-121
-
-
Kayagaki, N.1
Warming, S.2
Lamkanfi, M.3
Vande Walle, L.4
Louie, S.5
Dong, J.6
Newton, K.7
Qu, Y.8
Liu, J.9
Heldens, S.10
Zhang, J.11
Lee, W.P.12
Roose-Girma, M.13
Dixit, V.M.14
-
31
-
-
84883775365
-
Noncanonical inflammasome activation by intracellular LPS independent of TLR4
-
Kayagaki N, Wong MT, Stowe IB, Ramani SR, Gonzalez LC, Akashi-Takamura S, Miyake K, Zhang J, Lee WP, Muszynski A, Forsberg LS, Carlson RW, Dixit VM. Noncanonical inflammasome activation by intracellular LPS independent of TLR4. Science 341: 1246–1249, 2013.
-
(2013)
Science
, vol.341
, pp. 1246-1249
-
-
Kayagaki, N.1
Wong, M.T.2
Stowe3
Ramani, I.4
Gonzalez, L.C.5
Akashi-Takamura, S.6
Miyake, K.7
Zhang, J.8
Lee, W.P.9
Muszynski, A.10
Forsberg, L.S.11
Carlson, R.W.12
Dixit, V.M.13
-
32
-
-
84911992879
-
Noncanonical inflammasome activation of caspase-4/caspase-11 mediates epithelial defenses against enteric bacterial pathogens
-
Knodler LA, Crowley SM, Sham HP, Yang H, Wrande M, Ma C, Ernst RK, Steele-Mortimer O, Celli J, Vallance BA. Noncanonical inflammasome activation of caspase-4/caspase-11 mediates epithelial defenses against enteric bacterial pathogens. Cell Host Microbe 16: 249–256, 2014.
-
(2014)
Cell Host Microbe
, vol.16
, pp. 249-256
-
-
Knodler, L.A.1
Crowley, S.M.2
Sham, H.P.3
Yang, H.4
Wrande, M.5
Ma, C.6
Ernst, R.K.7
Steele-Mortimer, O.8
Celli, J.9
Vallance, B.A.10
-
33
-
-
77958590561
-
Ontology-based meta-analysis of global collections of high-throughput public data
-
Kupershmidt I, Su QJ, Grewal A, Sundaresh S, Halperin I, Flynn J, Shekar M, Wang H, Park J, Cui W, Wall GD, Wisotzkey R, Alag S, Akhtari S, Ronaghi M. Ontology-based meta-analysis of global collections of high-throughput public data. PloS One 5: 2010.
-
(2010)
Plos One
, pp. 5
-
-
Kupershmidt, I.1
Su2
Grewal, Q.J.A.3
Sundaresh, S.4
Halperin, I.5
Flynn, J.6
Shekar, M.7
Wang, H.8
Park, J.9
Cui, W.10
Wall, G.D.11
Wisotzkey, R.12
Alag, S.13
Akhtari, S.14
Ronaghi, M.15
-
34
-
-
84907584408
-
Reactive oxygen species regulate caspase-11 expression and activation of the noncanonical NLRP3 inflammasome during enteric pathogen infection
-
Lupfer CR, Anand PK, Liu Z, Stokes KL, Vogel P, Lamkanfi M, Kanneganti TD. Reactive oxygen species regulate caspase-11 expression and activation of the noncanonical NLRP3 inflammasome during enteric pathogen infection. PLoS Pathog 10: e1004410, 2014.
-
(2014)
Plos Pathog
, vol.10
-
-
Lupfer, C.R.1
Anand, P.K.2
Liu, Z.3
Stokes, K.L.4
Vogel, P.5
Lamkanfi, M.6
Kanneganti, T.D.7
-
35
-
-
0036671894
-
The inflammasome: A molecular platform triggering activation of inflammatory caspases and processing of proIL-beta
-
Martinon F, Burns K, Tschopp J. The inflammasome: A molecular platform triggering activation of inflammatory caspases and processing of proIL-beta. Mol Cell 10: 417–426, 2002.
-
(2002)
Mol Cell
, vol.10
, pp. 417-426
-
-
Martinon, F.1
Burns, K.2
Tschopp, J.3
-
36
-
-
0031921472
-
Expression of interleukin 1 beta and interleukin 1 beta converting enzyme by intestinal macrophages in health and inflammatory bowel disease
-
McAlindon ME, Hawkey CJ, Mahida YR. Expression of interleukin 1 beta and interleukin 1 beta converting enzyme by intestinal macrophages in health and inflammatory bowel disease. Gut 42: 214–219, 1998.
-
(1998)
Gut
, vol.42
, pp. 214-219
-
-
McAlindon, M.E.1
Hawkey, C.J.2
Mahida, Y.R.3
-
37
-
-
46749127004
-
DNA damage induced by chronic inflammation contributes to colon carcinogenesis in mice
-
Meira LB, Bugni JM, Green SL, Lee CW, Pang B, Borenshtein D, Rickman BH, Rogers AB, Moroski-Erkul CA, McFaline JL, Schauer DB, Dedon PC, Fox JG, Samson LD. DNA damage induced by chronic inflammation contributes to colon carcinogenesis in mice. J Clin Invest 118: 2516–2525, 2008.
-
(2008)
J Clin Invest
, vol.118
, pp. 2516-2525
-
-
Meira, L.B.1
Bugni, J.M.2
Green, S.L.3
Lee, C.W.4
Pang, B.5
Borenshtein, D.6
Rickman, B.H.7
Rogers, A.B.8
Moroski-Erkul, C.A.9
McFaline, J.L.10
Schauer, D.B.11
Dedon, P.C.12
Fox, J.G.13
Samson, L.D.14
-
38
-
-
34548162712
-
An inducible mouse model of colon carcinogenesis for the analysis of sporadic and inflammation-driven tumor progression
-
Neufert C, Becker C, Neurath MF. An inducible mouse model of colon carcinogenesis for the analysis of sporadic and inflammation-driven tumor progression. Nat Protoc 2: 1998–2004, 2007.
-
(2007)
Nat Protoc
, vol.2
, pp. 1998-2004
-
-
Neufert, C.1
Becker, C.2
Neurath, M.F.3
-
39
-
-
79959369355
-
Nod-like receptor pyrin domain-containing protein 6 (NLRP6) controls epithelial self-renewal and colorectal carcinogenesis upon injury
-
Normand S, Delanoye-Crespin A, Bressenot A, Huot L, Grandjean T, Peyrin-Biroulet L, Lemoine Y, Hot D, Chamaillard M. Nod-like receptor pyrin domain-containing protein 6 (NLRP6) controls epithelial self-renewal and colorectal carcinogenesis upon injury. Proc Natl Acad Sci USA 108: 9601–9606, 2011.
-
(2011)
Proc Natl Acad Sci USA
, vol.108
, pp. 9601-9606
-
-
Normand, S.1
Delanoye-Crespin, A.2
Bressenot, A.3
Huot, L.4
Grandjean, T.5
Peyrin-Biroulet, L.6
Lemoine, Y.7
Hot, D.8
Chamaillard, M.9
-
40
-
-
0036008967
-
Interleukin-1beta and tumor necrosis factor-alpha induce chemokine and matrix metalloproteinase gene expression in human co-lonic subepithelial myofibroblasts
-
Okuno T, Andoh A, Bamba S, Araki Y, Fujiyama Y, Fujiyama M, Bamba T. Interleukin-1beta and tumor necrosis factor-alpha induce chemokine and matrix metalloproteinase gene expression in human co-lonic subepithelial myofibroblasts. Scand J Gastroenterol 37: 317–324, 2002.
-
(2002)
Scand J Gastroenterol
, vol.37
, pp. 317-324
-
-
Okuno, T.1
Andoh, A.2
Bamba, S.3
Araki, Y.4
Fujiyama, Y.5
Fujiyama, M.6
Bamba, T.7
-
41
-
-
84867176929
-
IL-1 receptor antagonist ameliorates inflammasome-dependent alcoholic steatohepatitis in mice
-
Petrasek J, Bala S, Csak T, Lippai D, Kodys K, Menashy V, Barrieau M, Min SY, Kurt-Jones EA, Szabo G. IL-1 receptor antagonist ameliorates inflammasome-dependent alcoholic steatohepatitis in mice. J Clin Invest 122: 3476–3489, 2012.
-
(2012)
J Clin Invest
, vol.122
, pp. 3476-3489
-
-
Petrasek, J.1
Bala, S.2
Csak, T.3
Lippai, D.4
Kodys, K.5
Menashy, V.6
Barrieau, M.7
Min, S.Y.8
Kurt-Jones, E.A.9
Szabo, G.10
-
42
-
-
84864600268
-
TRIF licenses caspase-11-dependent NLRP3 inflammasome activation by gram-negative bacteria
-
Rathinam VA, Vanaja SK, Waggoner L, Sokolovska A, Becker C, Stuart LM, Leong JM, Fitzgerald KA. TRIF licenses caspase-11-dependent NLRP3 inflammasome activation by gram-negative bacteria. Cell 150: 606–619, 2012.
-
(2012)
Cell
, vol.150
, pp. 606-619
-
-
Rathinam, V.A.1
Vanaja, S.K.2
Waggoner, L.3
Sokolovska, A.4
Becker, C.5
Stuart, L.M.6
Leong, J.M.7
Fitzgerald, K.A.8
-
43
-
-
0027451455
-
Enhanced secretion of tumour necrosis factor-alpha, IL-6, and IL-1 beta by isolated lamina propria mononuclear cells from patients with ulcerative colitis and Crohn’s disease
-
Reinecker HC, Steffen M, Witthoeft T, Pflueger I, Schreiber S, MacDermott RP, Raedler A. Enhanced secretion of tumour necrosis factor-alpha, IL-6, and IL-1 beta by isolated lamina propria mononuclear cells from patients with ulcerative colitis and Crohn’s disease. Clin Exp Immunol 94: 174–181, 1993.
-
(1993)
Clin Exp Immunol
, vol.94
, pp. 174-181
-
-
Reinecker, H.C.1
Steffen, M.2
Witthoeft, T.3
Pflueger, I.4
Schreiber, S.5
Macdermott, R.P.6
Raedler, A.7
-
44
-
-
77955350419
-
MyD88-mediated signaling prevents development of adenocarcinomas of the colon: Role of interleukin 18
-
Salcedo R, Worschech A, Cardone M, Jones Y, Gyulai Z, Dai RM, Wang E, Ma W, Haines D, O’Huigin C, Marincola FM, Trinchieri G. MyD88-mediated signaling prevents development of adenocarcinomas of the colon: Role of interleukin 18. J Exp Med 207: 1625–1636, 2010.
-
(2010)
J Exp Med
, vol.207
, pp. 1625-1636
-
-
Salcedo, R.1
Worschech, A.2
Cardone, M.3
Jones, Y.4
Gyulai, Z.5
Dai, R.M.6
Wang, E.7
Ma, W.8
Haines9
O’Huigin, D.C.10
Marincola, F.M.11
Trinchieri, G.12
-
45
-
-
0023096624
-
Interleukin 1 in Crohn’s disease
-
Satsangi J, Wolstencroft RA, Cason J, Ainley CC, Dumonde DC, Thompson RP. Interleukin 1 in Crohn’s disease. Clin Exp Immunol 67: 594–605, 1987.
-
(1987)
Clin Exp Immunol
, vol.67
, pp. 594-605
-
-
Satsangi, J.1
Wolstencroft, R.A.2
Cason, J.3
Ainley, C.C.4
Dumonde, D.C.5
Thompson, R.P.6
-
46
-
-
84906571225
-
Inflammatory caspases are innate immune receptors for intracellular LPS
-
Shi J, Zhao Y, Wang Y, Gao W, Ding J, Li P, Hu L, Shao F. Inflammatory caspases are innate immune receptors for intracellular LPS. Nature 514: 187–192, 2014.
-
(2014)
Nature
, vol.514
, pp. 187-192
-
-
Shi, J.1
Zhao, Y.2
Wang, Y.3
Gao, W.4
Ding, J.5
Li, P.6
Hu, L.7
Shao, F.8
-
47
-
-
0036103112
-
Interleukin 18 is a primary mediator of the inflammation associated with dextran sulfate sodium induced colitis: Blocking interleu-kin 18 attenuates intestinal damage
-
Sivakumar PV, Westrich GM, Kanaly S, Garka K, Born TL, Derry JM, Viney JL. Interleukin 18 is a primary mediator of the inflammation associated with dextran sulfate sodium induced colitis: Blocking interleu-kin 18 attenuates intestinal damage. Gut 50: 812–820, 2002.
-
(2002)
Gut
, vol.50
, pp. 812-820
-
-
Sivakumar, P.V.1
Westrich, G.M.2
Kanaly, S.3
Garka, K.4
Born, T.L.5
Derry, J.M.6
Viney, J.L.7
-
48
-
-
68649088121
-
Interleukin-1 and IL-23 induce innate IL-17 production from gammadelta T cells, amplifying Th17 responses and autoimmunity
-
Sutton CE, Lalor SJ, Sweeney CM, Brereton CF, Lavelle EC, Mills KH. Interleukin-1 and IL-23 induce innate IL-17 production from gammadelta T cells, amplifying Th17 responses and autoimmunity. Immunity 31: 331–341, 2009.
-
(2009)
Immunity
, vol.31
, pp. 331-341
-
-
Sutton, C.E.1
Lalor, S.J.2
Sweeney, C.M.3
Brereton, C.F.4
Lavelle5
Mills, E.6
-
49
-
-
0035210979
-
Blockade of endogenous IL-18 ameliorates TNBS-induced colitis by decreasing local TNF-alpha production in mice
-
Ten Hove T, Corbaz A, Amitai H, Aloni S, Belzer I, Graber P, Drillenburg P, van Deventer SJ, Chvatchko Y, Te Velde AA. Blockade of endogenous IL-18 ameliorates TNBS-induced colitis by decreasing local TNF-alpha production in mice. Gastroenterology 121: 1372–1379, 2001.
-
(2001)
Gastroenterology
, vol.121
, pp. 1372-1379
-
-
Ten Hove, T.1
Corbaz, A.2
Amitai, H.3
Aloni, S.4
Belzer, I.5
Graber, P.6
Drillenburg, P.7
Van Deventer, S.J.8
Chvatchko, Y.9
Te Velde, Y.10
-
50
-
-
84894550453
-
Regulated necrosis: The expanding network of non-apoptotic cell death pathways
-
Vanden Berghe T, Linkermann A, Jouan-Lanhouet S, Walczak H, Vandenabeele P. Regulated necrosis: The expanding network of non-apoptotic cell death pathways. Nat Rev Mol Cell Biol 15: 135–147, 2014.
-
(2014)
Nat Rev Mol Cell Biol
, vol.15
, pp. 135-147
-
-
Vanden Berghe, T.1
Linkermann2
Jouan-Lanhouet, A.S.3
Walczak, H.4
Vandenabeele, P.5
-
51
-
-
0032548919
-
Murine caspase-11, an ICE-interacting protease, is essential for the activation of ICE
-
Wang S, Miura M, Jung YK, Zhu H, Li E, Yuan J. Murine caspase-11, an ICE-interacting protease, is essential for the activation of ICE. Cell 92: 501–509, 1998.
-
(1998)
Cell
, vol.92
, pp. 501-509
-
-
Wang, S.1
Miura, M.2
Jung, Y.K.3
Zhu, H.4
Li, E.5
Yuan, J.6
-
52
-
-
80055116409
-
Murine Colitis modeling using Dextran Sulfate Sodium (DSS)
-
Whittem CG, Williams AD, Williams CS. Murine Colitis modeling using Dextran Sulfate Sodium (DSS). J Vis Exp 19: 1652, 2010.
-
(2010)
J Vis Exp
, vol.19
, pp. 1652
-
-
Whittem, C.G.1
Williams, A.D.2
Williams, C.S.3
-
53
-
-
34548386663
-
Microbial pathogen-induced necrotic cell death mediated by the inflammasome components CIAS1/cryopyrin/ NLRP3 and ASC
-
Willingham SB, Bergstralh DT, O’Connor W, Morrison AC, Taxman DJ, Duncan JA, Barnoy S, Venkatesan MM, Flavell RA, Deshmukh M, Hoffman HM, Ting JP. Microbial pathogen-induced necrotic cell death mediated by the inflammasome components CIAS1/cryopyrin/ NLRP3 and ASC. Cell Host Microbe 2: 147–159, 2007.
-
(2007)
Cell Host Microbe
, vol.2
, pp. 147-159
-
-
Willingham, S.B.1
Bergstralh, D.T.2
O’Connor, W.3
Morrison, A.C.4
Taxman, D.J.5
Duncan, J.A.6
Barnoy, S.7
Venkatesan, M.M.8
Flavell, R.A.9
Deshmukh, M.10
Hoffman, H.M.11
Ting, J.P.12
-
54
-
-
34347262689
-
Chemically induced mouse models of intestinal inflammation
-
Wirtz S, Neufert C, Weigmann B, Neurath MF. Chemically induced mouse models of intestinal inflammation. Nat Protoc 2: 541–546, 2007.
-
(2007)
Nat Protoc
, vol.2
, pp. 541-546
-
-
Wirtz, S.1
Neufert, C.2
Weigmann, B.3
Neurath, M.F.4
-
55
-
-
84896691062
-
NLRP6 inflammasome orchestrates the colonic host-microbial interface by regulating goblet cell mucus secretion
-
Wlodarska M, Thaiss CA, Nowarski R, Henao-Mejia J, Zhang JP, Brown EM, Frankel G, Levy M, Katz MN, Philbrick WM, Elinav E, Finlay BB, Flavell RA. NLRP6 inflammasome orchestrates the colonic host-microbial interface by regulating goblet cell mucus secretion. Cell 156: 1045–1059, 2014.
-
(2014)
Cell
, vol.156
, pp. 1045-1059
-
-
Wlodarska, M.1
Thaiss, C.A.2
Nowarski, R.3
Henao-Mejia, J.4
Zhang, J.P.5
Brown, E.M.6
Frankel, G.7
Levy, M.8
Katz, M.N.9
Philbrick, W.M.10
Elinav, E.11
Finlay, B.B.12
Flavell, R.A.13
-
56
-
-
77950002937
-
The NLRP3 inflammasome protects against loss of epithelial integrity and mortality during experimental colitis
-
Zaki MH, Boyd KL, Vogel P, Kastan MB, Lamkanfi M, Kanneganti TD. The NLRP3 inflammasome protects against loss of epithelial integrity and mortality during experimental colitis. Immunity 32: 379–391, 2010.
-
(2010)
Immunity
, vol.32
, pp. 379-391
-
-
Zaki, M.H.1
Boyd, K.L.2
Vogel, P.3
Kastan, M.B.4
Lamkanfi, M.5
Kanneganti, T.D.6
|