Macrophage-Derived upd3 Cytokine Causes Impaired Glucose Homeostasis and Reduced Lifespan in Drosophila Fed a Lipid-Rich Diet

Immunity

Volumn 42, Issue 1, 2015, Pages 133-144

  Woodcock, Katie J ^a   Kierdorf, Katrin ^a   Pouchelon, Clara A ^a   Vivancos, Valérie ^a   Dionne, Marc S ^a   Geissmann, Frédéric ^a  

^a KING'S COLLEGE LONDON   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

CYTOKINE; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; JANUS KINASE; JANUS KINASE 1; STAT PROTEIN; DROSOPHILA PROTEIN; MITOGEN ACTIVATED PROTEIN KINASE KINASE 4; SCAVENGER RECEPTOR; SMALL INTERFERING RNA; UPD3 PROTEIN, DROSOPHILA;

ADULT; ANIMAL CELL; ANIMAL EXPERIMENT; ARTICLE; CONTROLLED STUDY; CYTOKINE PRODUCTION; DROSOPHILA MELANOGASTER; ENZYME ACTIVATION; FOOD INTAKE; GENE; GENE SILENCING; GLUCOSE HOMEOSTASIS; HYPERGLYCEMIA; INSULIN SENSITIVITY; LIFESPAN; LIPID DIET; LIPID STORAGE; MACROPHAGE; MALE; MOLECULAR BIOLOGY; NONHUMAN; PHENOTYPE; PRIORITY JOURNAL; SIGNAL TRANSDUCTION; UPD3 GENE; ADVERSE EFFECTS; AGING, PREMATURE; ANIMAL; CELL CULTURE; DROSOPHILA; GENETICS; HUMAN; IMMUNOLOGY; INFLAMMATION; INSULIN RESISTANCE; MACROPHAGE ACTIVATION; METABOLISM; OBESITY; PHYSIOLOGY;

AGING, PREMATURE; ANIMALS; CELLS, CULTURED; DIET, HIGH-FAT; DROSOPHILA; DROSOPHILA PROTEINS; HUMANS; INFLAMMATION; INSULIN RESISTANCE; JANUS KINASES; MACROPHAGE ACTIVATION; MACROPHAGES; MAP KINASE KINASE 4; OBESITY; RECEPTORS, SCAVENGER; RNA, SMALL INTERFERING; SIGNAL TRANSDUCTION; STAT TRANSCRIPTION FACTORS;

EID: 84921403806     PISSN: 10747613     EISSN: 10974180     Source Type: Journal    
DOI: 10.1016/j.immuni.2014.12.023     Document Type: Article

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