메뉴 건너뛰기




Volumn 42, Issue 16, 2014, Pages 10226-10234

How the misincorporation of ribonucleotides into genomic DNA can be both harmful and helpful to cells

Author keywords

[No Author keywords available]

Indexed keywords

DEOXYRIBONUCLEOTIDE; DNA DIRECTED DNA POLYMERASE DELTA; DNA DIRECTED DNA POLYMERASE EPSILON; DNA POLYMERASE; GENOMIC DNA; RIBONUCLEASE H; RIBONUCLEASE H2; RIBONUCLEOTIDE; UNCLASSIFIED DRUG; DNA; RIBONUCLEASE HII;

EID: 84921329939     PISSN: 03051048     EISSN: 13624962     Source Type: Journal    
DOI: 10.1093/nar/gku773     Document Type: Review
Times cited : (62)

References (65)
  • 1
    • 0031042722 scopus 로고    scopus 로고
    • Choosing the right sugar: How polymerases select a nucleotide substrate
    • Joyce, C.M. Joyce, C.M. (1997) Choosing the right sugar: how polymerases select a nucleotide substrate. Proc. Natl. Acad. Sci. U.S.A., 94, 1619-1622.
    • (1997) Proc. Natl. Acad. Sci. U.S.A. , vol.94 , pp. 1619-1622
    • Joyce, C.M.1    Joyce, C.M.2
  • 5
    • 0033575087 scopus 로고    scopus 로고
    • Kinetics of RNA degradation by specific base catalysis of transesterification involving the 2′-hydroxyl group
    • Li, Y. and Breaker, R.R.Li, Y. and Breaker, R.R. (1999) Kinetics of RNA degradation by specific base catalysis of transesterification involving the 2′-hydroxyl group. J. Am. Chem. Soc., 121, 5326-5372.
    • (1999) J. Am. Chem. Soc. , vol.121 , pp. 5326-5372
    • Li, Y.1    Breaker, R.R.2    Li, Y.3    Breaker, R.R.4
  • 10
    • 84861578543 scopus 로고    scopus 로고
    • Enzymatic removal of ribonucleotides from DNA is essential for mammalian genome integrity and development
    • Reijns, M.A., Rabe, B., Rigby, R.E., Mill, P., Astell, K.R., Lettice, L.A., Boyle, S., Leitch, A., Keighren, M., and Kilanowski, F. et al. Reijns, M.A., Rabe, B., Rigby, R.E., Mill, P., Astell, K.R., Lettice, L.A., Boyle, S., Leitch, A., Keighren, M., and Kilanowski, F. (2012) Enzymatic removal of ribonucleotides from DNA is essential for mammalian genome integrity and development. Cell, 149, 1008-1022.
    • (2012) Cell , vol.149 , pp. 1008-1022
    • Reijns, M.A.1    Rabe, B.2    Rigby, R.E.3    Mill, P.4    Astell, K.R.5    Lettice, L.A.6    Boyle, S.7    Leitch, A.8    Keighren, M.9    Kilanowski, F.10
  • 12
    • 0027299690 scopus 로고
    • Conformational influence of the ribose 2′-hydroxyl group: Crystal structures of DNA-RNA chimeric duplexes
    • Egli, M., Usman, N., and Rich, A.Egli, M., Usman, N., and Rich, A. (1993) Conformational influence of the ribose 2′-hydroxyl group: crystal structures of DNA-RNA chimeric duplexes. Biochemistry, 32, 3221-3237.
    • (1993) Biochemistry , vol.32 , pp. 3221-3237
    • Egli, M.1    Usman, N.2    Rich, A.3    Egli, M.4    Usman, N.5    Rich, A.6
  • 17
    • 0025911370 scopus 로고
    • Ribonuclease H from K562 human erythroleukemia cells. Purification, characterization, and substrate specificity
    • Eder, P.S. and Walder, J.A.Eder, P.S. and Walder, J.A. (1991) Ribonuclease H from K562 human erythroleukemia cells. Purification, characterization, and substrate specificity. J. Biol. Chem., 266, 6472-6479.
    • (1991) J. Biol. Chem. , vol.266 , pp. 6472-6479
    • Eder, P.S.1    Walder, J.A.2    Eder, P.S.3    Walder, J.A.4
  • 18
    • 0033547793 scopus 로고    scopus 로고
    • Identification of the genes encoding Mn2+-dependent RNase HII and Mg2+-dependent RNase HIII from Bacillus subtilis: Classification of RNases H into three families
    • Ohtani, N., Haruki, M., Morikawa, M., Crouch, R.J., Itaya, M., and Kanaya, S.Ohtani, N., Haruki, M., Morikawa, M., Crouch, R.J., Itaya, M., and Kanaya, S. (1999) Identification of the genes encoding Mn2+-dependent RNase HII and Mg2+-dependent RNase HIII from Bacillus subtilis: classification of RNases H into three families. Biochemistry, 38, 605-618.
    • (1999) Biochemistry , vol.38 , pp. 605-618
    • Ohtani, N.1    Haruki, M.2    Morikawa, M.3    Crouch, R.J.4    Itaya, M.5    Kanaya, S.6    Ohtani, N.7    Haruki, M.8    Morikawa, M.9    Crouch, R.J.10    Itaya, M.11    Kanaya, S.12
  • 20
    • 21244451435 scopus 로고    scopus 로고
    • Crystal structures of RNase H bound to an RNA/DNA hybrid: Substrate specificity and metal-dependent catalysis
    • Nowotny, M., Gaidamakov, S.A., Crouch, R.J., and Yang, W.Nowotny, M., Gaidamakov, S.A., Crouch, R.J., and Yang, W. (2005) Crystal structures of RNase H bound to an RNA/DNA hybrid: substrate specificity and metal-dependent catalysis. Cell, 121, 1005-1016.
    • (2005) Cell , vol.121 , pp. 1005-1016
    • Nowotny, M.1    Gaidamakov, S.A.2    Crouch, R.J.3    Yang, W.4    Nowotny, M.5    Gaidamakov, S.A.6    Crouch, R.J.7    Yang, W.8
  • 21
    • 0027213005 scopus 로고
    • Substrate specificity of human RNase H1 and its role in excision repair of ribose residues misincorporated in DNA
    • Eder, P.S., Walder, R.Y., and Walder, J.A.Eder, P.S., Walder, R.Y., and Walder, J.A. (1993) Substrate specificity of human RNase H1 and its role in excision repair of ribose residues misincorporated in DNA. Biochimie, 75, 123-126.
    • (1993) Biochimie , vol.75 , pp. 123-126
    • Eder, P.S.1    Walder, R.Y.2    Walder, J.A.3    Eder, P.S.4    Walder, R.Y.5    Walder, J.A.6
  • 23
    • 0033512305 scopus 로고    scopus 로고
    • Saccharomyces cerevisiae RNase H(35) functions in RNA primer removal during lagging-strand DNA synthesis, most efficiently in cooperation with Rad27 nuclease
    • Qiu, J., Qian, Y., Frank, P., Wintersberger, U., and Shen, B.Qiu, J., Qian, Y., Frank, P., Wintersberger, U., and Shen, B. (1999) Saccharomyces cerevisiae RNase H(35) functions in RNA primer removal during lagging-strand DNA synthesis, most efficiently in cooperation with Rad27 nuclease. Mol. Cell. Biol., 19, 8361-8371.
    • (1999) Mol. Cell. Biol. , vol.19 , pp. 8361-8371
    • Qiu, J.1    Qian, Y.2    Frank, P.3    Wintersberger, U.4    Shen, B.5    Qiu, J.6    Qian, Y.7    Frank, P.8    Wintersberger, U.9    Shen, B.10
  • 24
    • 33747379083 scopus 로고    scopus 로고
    • The Forkhead transcription factor Hcm1 regulates chromosome segregation genes and fills the S-phase gap in the transcriptional circuitry of the cell cycle
    • Pramila, T., Wu, W., Miles, S., Noble, W.S., and Breeden, L.L.Pramila, T., Wu, W., Miles, S., Noble, W.S., and Breeden, L.L. (2006) The Forkhead transcription factor Hcm1 regulates chromosome segregation genes and fills the S-phase gap in the transcriptional circuitry of the cell cycle. Genes Dev., 20, 2266-2278.
    • (2006) Genes Dev. , vol.20 , pp. 2266-2278
    • Pramila, T.1    Wu, W.2    Miles, S.3    Noble, W.S.4    Breeden, L.L.5    Pramila, T.6    Wu, W.7    Miles, S.8    Noble, W.S.9    Breeden, L.L.10
  • 33
    • 84904248751 scopus 로고    scopus 로고
    • Avoidance of ribonucleotide-induced mutations by RNase H2 and Srs2-Exo1 mechanisms
    • Potenski, C.J., Niu, H., Sung, P., and Klein, H.L.Potenski, C.J., Niu, H., Sung, P., and Klein, H.L. (2014) Avoidance of ribonucleotide-induced mutations by RNase H2 and Srs2-Exo1 mechanisms. Nature, 511, 251-254.
    • (2014) Nature , vol.511 , pp. 251-254
    • Potenski, C.J.1    Niu, H.2    Sung, P.3    Klein, H.L.4    Potenski, C.J.5    Niu, H.6    Sung, P.7    Klein, H.L.8
  • 36
    • 79955097646 scopus 로고    scopus 로고
    • Mismatch repair-independent tandem repeat sequence instability resulting from ribonucleotide incorporation by DNA polymerase epsilon
    • Clark, A.B., Lujan, S.A., Kissling, G.E., and Kunkel, T.A.Clark, A.B., Lujan, S.A., Kissling, G.E., and Kunkel, T.A. (2011) Mismatch repair-independent tandem repeat sequence instability resulting from ribonucleotide incorporation by DNA polymerase epsilon. DNA Repair, 10, 476-482.
    • (2011) DNA Repair , vol.10 , pp. 476-482
    • Clark, A.B.1    Lujan, S.A.2    Kissling, G.E.3    Kunkel, T.A.4    Clark, A.B.5    Lujan, S.A.6    Kissling, G.E.7    Kunkel, T.A.8
  • 40
    • 0031310666 scopus 로고    scopus 로고
    • Site-specific ribonuclease activity of eukaryotic DNA topoisomerase i
    • Sekiguchi, J. and Shuman, S.Sekiguchi, J. and Shuman, S. (1997) Site-specific ribonuclease activity of eukaryotic DNA topoisomerase I. Mol. Cell, 1, 89-97.
    • (1997) Mol. Cell , vol.1 , pp. 89-97
    • Sekiguchi, J.1    Shuman, S.2    Sekiguchi, J.3    Shuman, S.4
  • 42
    • 0024058351 scopus 로고
    • Genetic control of intrachromosomal recombination in Saccharomyces cerevisiae. I. Isolation and genetic characterization of hyper-recombination mutations
    • Aguilera, A. and Klein, H.L.Aguilera, A. and Klein, H.L. (1988) Genetic control of intrachromosomal recombination in Saccharomyces cerevisiae. I. Isolation and genetic characterization of hyper-recombination mutations. Genetics, 119, 779-790.
    • (1988) Genetics , vol.119 , pp. 779-790
    • Aguilera, A.1    Klein, H.L.2    Aguilera, A.3    Klein, H.L.4
  • 45
    • 0029048761 scopus 로고
    • A model for topoisomerase I-mediated insertions and deletions with duplex DNA substrates containing branches, nicks, and gaps
    • Henningfeld, K.A. and Hecht, S.M.Henningfeld, K.A. and Hecht, S.M. (1995) A model for topoisomerase I-mediated insertions and deletions with duplex DNA substrates containing branches, nicks, and gaps. Biochemistry, 34, 6120-6129.
    • (1995) Biochemistry , vol.34 , pp. 6120-6129
    • Henningfeld, K.A.1    Hecht, S.M.2    Henningfeld, K.A.3    Hecht, S.M.4
  • 46
    • 79951620951 scopus 로고    scopus 로고
    • VUnlocking the sugar "steric gate" of DNA polymerases
    • Brown, J.A. and Suo, Z.Brown, J.A. and Suo, Z. (2011) Unlocking the sugar "steric gate" of DNA polymerases. Biochemistry, 50, 1135-1142.
    • (2011) Biochemistry , vol.50 , pp. 1135-1142
    • Brown, J.A.1    Suo, Z.2    Brown, J.A.3    Suo, Z.4
  • 47
    • 33746522835 scopus 로고    scopus 로고
    • Mutations in genes encoding ribonuclease H2 subunits cause Aicardi-Goutieres syndrome and mimic congenital viral brain infection
    • Crow, Y.J., Leitch, A., Hayward, B.E., Garner, A., Parmar, R., Griffith, E., Ali, M., Semple, C., Aicardi, J., and Babul-Hirji, R. et al.Crow, Y.J., Leitch, A., Hayward, B.E., Garner, A., Parmar, R., Griffith, E., Ali, M., Semple, C., Aicardi, J., and Babul-Hirji, R. (2006) Mutations in genes encoding ribonuclease H2 subunits cause Aicardi-Goutieres syndrome and mimic congenital viral brain infection. Nat. Genet., 38, 910-916.
    • (2006) Nat. Genet. , vol.38 , pp. 910-916
    • Crow, Y.J.1    Leitch, A.2    Hayward, B.E.3    Garner, A.4    Parmar, R.5    Griffith, E.6    Ali, M.7    Semple, C.8    Aicardi, J.9    Babul-Hirji, R.10
  • 48
    • 0021336060 scopus 로고
    • A progressive familial encephalopathy in infancy with calcifications of the basal ganglia and chronic cerebrospinal fluid lymphocytosis
    • Aicardi, J. and Goutieres, F.Aicardi, J. and Goutieres, F. (1984) A progressive familial encephalopathy in infancy with calcifications of the basal ganglia and chronic cerebrospinal fluid lymphocytosis. Ann. Neurol., 15, 49-54.
    • (1984) Ann. Neurol. , vol.15 , pp. 49-54
    • Aicardi, J.1    Goutieres, F.2    Aicardi, J.3    Goutieres, F.4
  • 50
    • 67649861901 scopus 로고    scopus 로고
    • Mutations involved in Aicardi-Goutieres syndrome implicate SAMHD1 as regulator of the innate immune response
    • Rice, G.I., Bond, J., Asipu, A., Brunette, R.L., Manfield, I.W., Carr, I.M., Fuller, J.C., Jackson, R.M., Lamb, T., and Briggs, T.A. et al.Rice, G.I., Bond, J., Asipu, A., Brunette, R.L., Manfield, I.W., Carr, I.M., Fuller, J.C., Jackson, R.M., Lamb, T., and Briggs, T.A. (2009) Mutations involved in Aicardi-Goutieres syndrome implicate SAMHD1 as regulator of the innate immune response. Nat. Genet., 41, 829-832.
    • (2009) Nat. Genet. , vol.41 , pp. 829-832
    • Rice, G.I.1    Bond, J.2    Asipu, A.3    Brunette, R.L.4    Manfield, I.W.5    Carr, I.M.6    Fuller, J.C.7    Jackson, R.M.8    Lamb, T.9    Briggs, T.A.10
  • 51
    • 33746581694 scopus 로고    scopus 로고
    • Mutations in the gene encoding the 3′-5′DNA exonuclease TREX1 cause Aicardi-Goutieres syndrome at the AGS1 locus
    • Crow, Y.J., Hayward, B.E., Parmar, R., Robins, P., Leitch, A., Ali, M., Black, D.N., van Bokhoven, H., Brunner, H.G., and Hamel, B.C. et al.Crow, Y.J., Hayward, B.E., Parmar, R., Robins, P., Leitch, A., Ali, M., Black, D.N., van Bokhoven, H., Brunner, H.G., and Hamel, B.C. (2006) Mutations in the gene encoding the 3′-5′DNA exonuclease TREX1 cause Aicardi-Goutieres syndrome at the AGS1 locus. Nat. Genet., 38, 917-920.
    • (2006) Nat. Genet. , vol.38 , pp. 917-920
    • Crow, Y.J.1    Hayward, B.E.2    Parmar, R.3    Robins, P.4    Leitch, A.5    Ali, M.6    Black, D.N.7    Van Bokhoven, H.8    Brunner, H.G.9    Hamel, B.C.10
  • 52
    • 84868207785 scopus 로고    scopus 로고
    • Mutations in ADAR1 cause Aicardi-Goutieres syndrome associated with a type i interferon signature
    • Rice, G.I., Kasher, P.R., Forte, G.M., Mannion, N.M., Greenwood, S.M., Szynkiewicz, M., Dickerson, J.E., Bhaskar, S.S., Zampini, M., and Briggs, T.A. et al.Rice, G.I., Kasher, P.R., Forte, G.M., Mannion, N.M., Greenwood, S.M., Szynkiewicz, M., Dickerson, J.E., Bhaskar, S.S., Zampini, M., and Briggs, T.A. (2012) Mutations in ADAR1 cause Aicardi-Goutieres syndrome associated with a type I interferon signature. Nat. Genet., 44, 1243-1248.
    • (2012) Nat. Genet. , vol.44 , pp. 1243-1248
    • Rice, G.I.1    Kasher, P.R.2    Forte, G.M.3    Mannion, N.M.4    Greenwood, S.M.5    Szynkiewicz, M.6    Dickerson, J.E.7    Bhaskar, S.S.8    Zampini, M.9    Briggs, T.A.10
  • 54
    • 77951737544 scopus 로고    scopus 로고
    • Expanding the phenotypic spectrum of lupus erythematosus in Aicardi-Goutieres syndrome
    • Ramantani, G., Kohlhase, J., Hertzberg, C., Innes, A.M., Engel, K., Hunger, S., Borozdin, W., Mah, J.K., Ungerath, K., and Walkenhorst, H. et al.Ramantani, G., Kohlhase, J., Hertzberg, C., Innes, A.M., Engel, K., Hunger, S., Borozdin, W., Mah, J.K., Ungerath, K., and Walkenhorst, H. (2010) Expanding the phenotypic spectrum of lupus erythematosus in Aicardi-Goutieres syndrome. Arthritis Rheumat., 62, 1469-1477.
    • (2010) Arthritis Rheumat. , vol.62 , pp. 1469-1477
    • Ramantani, G.1    Kohlhase, J.2    Hertzberg, C.3    Innes, A.M.4    Engel, K.5    Hunger, S.6    Borozdin, W.7    Mah, J.K.8    Ungerath, K.9    Walkenhorst, H.10
  • 55
    • 84919667874 scopus 로고    scopus 로고
    • Identification of novel genes involved in gastric carcinogenesis by suppression subtractive hybridization
    • Mottaghi-Dastjerdi, N., Soltany-Rezaee-Rad, M., Sepehrizadeh, Z., Roshandel, G., Ebrahimifard, F., and Setayesh, N. doi:10.1177/0960327114532386Mottaghi-Dastjerdi, N., Soltany-Rezaee-Rad, M., Sepehrizadeh, Z., Roshandel, G., Ebrahimifard, F., and Setayesh, N. (2014) Identification of novel genes involved in gastric carcinogenesis by suppression subtractive hybridization. Hum. Exp. Toxicol, .
    • (2014) Hum. Exp. Toxicol
    • Mottaghi-Dastjerdi, N.1    Soltany-Rezaee-Rad, M.2    Sepehrizadeh, Z.3    Roshandel, G.4    Ebrahimifard, F.5    Setayesh, N.6
  • 61
    • 43749100687 scopus 로고    scopus 로고
    • Bacterial nonhomologous end joining ligases preferentially seal breaks with a 3′-OH monoribonucleotide
    • Zhu, H. and Shuman, S.Zhu, H. and Shuman, S. (2008) Bacterial nonhomologous end joining ligases preferentially seal breaks with a 3′-OH monoribonucleotide. J. Biol. Chem., 283, 8331-8339.
    • (2008) J. Biol. Chem. , vol.283 , pp. 8331-8339
    • Zhu, H.1    Shuman, S.2    Zhu, H.3    Shuman, S.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.