Mutagenic processing of ribonucleotides in DNA by yeast topoisomerase I

Science

Volumn 332, Issue 6037, 2011, Pages 1561-1564

  Kim, Nayun ^a   Huang, Shar Yin N ^b   Williams, Jessica S ^c   Li, Yue C ^a   Clark, Alan B ^c   Cho, Jang Eun ^a   Kunkel, Thomas A ^c   Pommier, Yves ^b   Jinks Robertson, Sue ^a  

^a DUKE UNIVERSITY MEDICAL CENTER   (United States)

^b NATIONAL CANCER INSTITUTE   (United States)

^c NATIONAL INSTITUTE OF ENVIRONMENTAL HEALTH SCIENCES   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CAMPTOTHECIN; DEOXYRIBOTHYMINE; DNA TOPOISOMERASE; DOUBLE STRANDED DNA; GENOMIC DNA; RIBONUCLEOSIDE MONOPHOSPHATE; RIBONUCLEOTIDE; RIBOURACIL; THYMINE; UNCLASSIFIED DRUG; URACIL DERIVATIVE;

BIOCHEMISTRY; DNA; ENZYME ACTIVITY; METABOLISM; MUTATION; PUBLIC HEALTH; RNA; YEAST;

ARTICLE; CAN1 GENE; CELL DIFFERENTIATION; DNA FLANKING REGION; DNA REPLICATION; DNA SUPERCOILING; ENZYME ACTIVITY; ENZYME CONFORMATION; GENE; GENE DELETION; GENE MUTATION; GENETIC TRANSCRIPTION; MICROSATELLITE INSTABILITY; MISMATCH REPAIR; MUTAGENESIS; NONHUMAN; PRIORITY JOURNAL; SHORT TANDEM REPEAT; SINGLE STRANDED DNA BREAK; YEAST;

AMINO ACID TRANSPORT SYSTEMS, BASIC; BASE SEQUENCE; CAMPTOTHECIN; CANAVANINE; DNA BREAKS; DNA TOPOISOMERASES, TYPE I; DNA, FUNGAL; DNA, SINGLE-STRANDED; MICROSATELLITE REPEATS; MOLECULAR SEQUENCE DATA; MUTAGENESIS; NUCLEIC ACID CONFORMATION; RIBONUCLEASE H; RIBONUCLEOTIDES; SACCHAROMYCES CEREVISIAE; SACCHAROMYCES CEREVISIAE PROTEINS; SEQUENCE DELETION; TRANSCRIPTION, GENETIC;

SACCHAROMYCETALES;

EID: 79959504063     PISSN: 00368075     EISSN: 10959203     Source Type: Journal    
DOI: 10.1126/science.1205016     Document Type: Article

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