메뉴 건너뛰기




Volumn 1, Issue 1, 1997, Pages 89-97

Site-specific ribonuclease activity of eukaryotic DNA topoisomerase I

Author keywords

[No Author keywords available]

Indexed keywords

DNA; DNA TOPOISOMERASE; MESSENGER RNA; PHOSPHATE; RIBONUCLEASE; THYMIDINE; TYROSINE; URIDINE;

EID: 0031310666     PISSN: 10972765     EISSN: None     Source Type: Journal    
DOI: 10.1016/S1097-2765(00)80010-6     Document Type: Article
Times cited : (140)

References (48)
  • 1
    • 0024293223 scopus 로고
    • A tetrahedral intermediate in the EPSP synthase reaction observed by rapid quench kinetics
    • Anderson, K.S., Sikorski, J.A., and Johnson, K.A. (1988). A tetrahedral intermediate in the EPSP synthase reaction observed by rapid quench kinetics. Biochemistry 27, 7395-7406.
    • (1988) Biochemistry , vol.27 , pp. 7395-7406
    • Anderson, K.S.1    Sikorski, J.A.2    Johnson, K.A.3
  • 2
    • 0025743997 scopus 로고
    • Deletion analysis of a multifunctional yeast tRNA ligase polypeptide
    • Apostol, B.L., Westaway, S.K., Abelson, J., and Greer, C.L. (1991). Deletion analysis of a multifunctional yeast tRNA ligase polypeptide. J. Biol. Chem. 266, 7445-7455.
    • (1991) J. Biol. Chem. , vol.266 , pp. 7445-7455
    • Apostol, B.L.1    Westaway, S.K.2    Abelson, J.3    Greer, C.L.4
  • 3
    • 0020740241 scopus 로고
    • Analysis of numerical methods for computer simulation of kinetic processes: Development of KINSIM - A flexible, portable system
    • Barshop, B.A., Wrenn, R.F., and Frieden, C. (1983). Analysis of numerical methods for computer simulation of kinetic processes: development of KINSIM - a flexible, portable system. Anal. Biochem. 130, 134-145.
    • (1983) Anal. Biochem. , vol.130 , pp. 134-145
    • Barshop, B.A.1    Wrenn, R.F.2    Frieden, C.3
  • 4
    • 77956940788 scopus 로고
    • Pancreatic ribonuclease
    • Blackburn, P., and Moore, S. (1982). Pancreatic ribonuclease. Enzymes 15b, 317-433.
    • (1982) Enzymes , vol.15 B , pp. 317-433
    • Blackburn, P.1    Moore, S.2
  • 5
    • 1842333250 scopus 로고    scopus 로고
    • Mutational analysis of 39 residues of vaccinia DNA topoisomerase identifies Lys-220, Arg-223, and Asn-228as important for covalent catalysis
    • Cheng, C., Wang, L.K., Sekiguchi, J., and Shuman, S. (1997). Mutational analysis of 39 residues of vaccinia DNA topoisomerase identifies Lys-220, Arg-223, and Asn-228as important for covalent catalysis. J. Biol. Chem. 272, 8263-8269.
    • (1997) J. Biol. Chem. , vol.272 , pp. 8263-8269
    • Cheng, C.1    Wang, L.K.2    Sekiguchi, J.3    Shuman, S.4
  • 6
    • 0028140256 scopus 로고
    • Characterization of intra- and intermolecular DNA ligation mediated by eukaryotic topoisomerase I
    • Christiansen, K., and Westergaard, O. (1994). Characterization of intra- and intermolecular DNA ligation mediated by eukaryotic topoisomerase I. J. Biol. Chem. 269, 721-729.
    • (1994) J. Biol. Chem. , vol.269 , pp. 721-729
    • Christiansen, K.1    Westergaard, O.2
  • 7
    • 0027211007 scopus 로고
    • Eukaryotic topoisomerase I-mediated cleavage requires bipartite DNA interaction
    • Christiansen, K., Svejstrup, A.B.D., Andersen, A.M., and Westergaard, O. (1993). Eukaryotic topoisomerase I-mediated cleavage requires bipartite DNA interaction. J. Biol. Chem. 268, 9690-9701.
    • (1993) J. Biol. Chem. , vol.268 , pp. 9690-9701
    • Christiansen, K.1    Svejstrup, A.B.D.2    Andersen, A.M.3    Westergaard, O.4
  • 8
    • 0026660190 scopus 로고
    • Escherichia coli topoisomerase III-catalyzed cleavage of RNA
    • DiGate, R.J.,and Marians, K.J. (1992). Escherichia coli topoisomerase III-catalyzed cleavage of RNA. J. Biol. Chem. 267, 20532-20535.
    • (1992) J. Biol. Chem. , vol.267 , pp. 20532-20535
    • DiGate, R.J.1    Marians, K.J.2
  • 9
    • 0026330796 scopus 로고
    • HIV-1 DNA integration: Mechanism of viral DNA cleavage and DNA strand transfer
    • Engelman, A., Mizuuchi, K., and Craigie, R. (1991). HIV-1 DNA integration: mechanism of viral DNA cleavage and DNA strand transfer. Cell 67, 1211-1221.
    • (1991) Cell , vol.67 , pp. 1211-1221
    • Engelman, A.1    Mizuuchi, K.2    Craigie, R.3
  • 10
    • 0021988616 scopus 로고
    • Cyclization of RNA 3′-terminal phosphate by cyclase from HeLa cells proceeds via formation of N(3′)pp(5′)A activated intermediate
    • Filipowicz, W., Strugala, K., Konarska, M., and Shatkin, A.J. (1985). Cyclization of RNA 3′-terminal phosphate by cyclase from HeLa cells proceeds via formation of N(3′)pp(5′)A activated intermediate. Proc. Natl. Acad. Sci. USA 82, 1316-1320.
    • (1985) Proc. Natl. Acad. Sci. USA , vol.82 , pp. 1316-1320
    • Filipowicz, W.1    Strugala, K.2    Konarska, M.3    Shatkin, A.J.4
  • 11
    • 0030926016 scopus 로고    scopus 로고
    • The human 3′-terminal phosphate cyclase is a member of a new family of proteins conserved in eukarya, bacteria, and archaea
    • Genschik, P., Billy, E., Swianiewicz, M., and Filipowicz, W. (1997). The human 3′-terminal phosphate cyclase is a member of a new family of proteins conserved in eukarya, bacteria, and archaea. EMBO J. 16, 2955-2967.
    • (1997) EMBO J. , vol.16 , pp. 2955-2967
    • Genschik, P.1    Billy, E.2    Swianiewicz, M.3    Filipowicz, W.4
  • 12
    • 0022625953 scopus 로고
    • Assembly of a tRNA splicing complex: Evidence for concerted excision and joining steps in splicing in vitro
    • Greer, C.L. (1986). Assembly of a tRNA splicing complex: evidence for concerted excision and joining steps in splicing in vitro. Mol. Cell. Biol. 6, 635-644.
    • (1986) Mol. Cell. Biol. , vol.6 , pp. 635-644
    • Greer, C.L.1
  • 13
    • 0028147370 scopus 로고
    • Mutations of vaccinia virus DNA topoisomerase I that stabilize the cleavage complex
    • Gupta, M., Zhu, C.-X., and Tse-Dinh, Y.-C. (1994). Mutations of vaccinia virus DNA topoisomerase I that stabilize the cleavage complex. J. Biol. Chem. 269, 573-578.
    • (1994) J. Biol. Chem. , vol.269 , pp. 573-578
    • Gupta, M.1    Zhu, C.-X.2    Tse-Dinh, Y.-C.3
  • 14
    • 0024324205 scopus 로고
    • On the mechanism of topoisomerase I inhibition by camptothecin: Evidence for binding to an enzyme-DNA complex
    • Hertzberg, R.P., Caranfa, M J., and Hecht, S.M. (1989). On the mechanism of topoisomerase I inhibition by camptothecin: evidence for binding to an enzyme-DNA complex. Biochemistry 28, 4629-4638.
    • (1989) Biochemistry , vol.28 , pp. 4629-4638
    • Hertzberg, R.P.1    Caranfa, M.J.2    Hecht, S.M.3
  • 15
    • 0022340594 scopus 로고
    • Camptothecin induces protein-linked DNA breaks via mammalian DNA topoisomerase I
    • Hsiang, Y., Hertzberg, R., Hecht, S., and Liu, L.F. (1985). Camptothecin induces protein-linked DNA breaks via mammalian DNA topoisomerase I. J. Biol. Chem. 260, 14873-14878.
    • (1985) J. Biol. Chem. , vol.260 , pp. 14873-14878
    • Hsiang, Y.1    Hertzberg, R.2    Hecht, S.3    Liu, L.F.4
  • 16
    • 0025719903 scopus 로고
    • Effect of local DNA sequence on topoisomerase I cleavage in the presence or absence of camptothecin
    • Jaxel, C., Capranico, G., Kerrigan, D., Kohn, K.W., and Pommier, Y. (1991). Effect of local DNA sequence on topoisomerase I cleavage in the presence or absence of camptothecin. J. Biol. Chem. 266, 20418-20423.
    • (1991) J. Biol. Chem. , vol.266 , pp. 20418-20423
    • Jaxel, C.1    Capranico, G.2    Kerrigan, D.3    Kohn, K.W.4    Pommier, Y.5
  • 17
    • 0027248517 scopus 로고
    • Mechanism of site-specific recombination: Logic of assembling recombinase catalytic site from fractional active sites
    • Lee, J., and Jayaram, M. (1993). Mechanism of site-specific recombination: logic of assembling recombinase catalytic site from fractional active sites. J. Biol. Chem. 268, 17564-17579.
    • (1993) J. Biol. Chem. , vol.268 , pp. 17564-17579
    • Lee, J.1    Jayaram, M.2
  • 18
    • 0027528787 scopus 로고
    • A novel mutation in DNA topoisomerase I of yeast causes DNA damage and RAD9-dependent cell cycle arrest
    • Levin, N.A., Bjornsti, M.A., and Fink, G.R. (1993). A novel mutation in DNA topoisomerase I of yeast causes DNA damage and RAD9-dependent cell cycle arrest. Genetics 133, 799-814.
    • (1993) Genetics , vol.133 , pp. 799-814
    • Levin, N.A.1    Bjornsti, M.A.2    Fink, G.R.3
  • 19
    • 0026565203 scopus 로고
    • Cyclic 2′, 3′-phophates and nontemplated nucleotides at the 3' end of spliceosomal U6 small nuclear RNAs
    • Lund, E., and Dahlberg, J.E. (1992). Cyclic 2′, 3′-phophates and nontemplated nucleotides at the 3' end of spliceosomal U6 small nuclear RNAs. Science 255, 327-330.
    • (1992) Science , vol.255 , pp. 327-330
    • Lund, E.1    Dahlberg, J.E.2
  • 20
    • 0030962069 scopus 로고    scopus 로고
    • Alterations in the catalytic activity of yeast DNA topoisomerase I result in cell cycle arrest and cell death
    • Megonigal, M.D., Fertala, J., and Bjoprnsti, M.A. (1997). Alterations in the catalytic activity of yeast DNA topoisomerase I result in cell cycle arrest and cell death. J. Biol. Chem. 272, 12801-12808.
    • (1997) J. Biol. Chem. , vol.272 , pp. 12801-12808
    • Megonigal, M.D.1    Fertala, J.2    Bjoprnsti, M.A.3
  • 21
    • 0020710638 scopus 로고
    • Precise excision of intervening sequences from precursor tRNAs by a membrane-associated yeast endonuclease
    • Peebles, C.L., Gegenheimer, P., and Abelson, J. (1983). Precise excision of intervening sequences from precursor tRNAs by a membrane-associated yeast endonuclease. Cell 32, 525-536.
    • (1983) Cell , vol.32 , pp. 525-536
    • Peebles, C.L.1    Gegenheimer, P.2    Abelson, J.3
  • 22
    • 0030806205 scopus 로고    scopus 로고
    • DNA strand transfer reactions catalyzed by vaccinia topoisomerase: Hydrolysis and glycerololysis of the covalent protein-DNA intermediate
    • Petersen, B.Ø., and Shuman, S. (1997a). DNA strand transfer reactions catalyzed by vaccinia topoisomerase: hydrolysis and glycerololysis of the covalent protein-DNA intermediate. Nucleic Acids Res. 25, 2091-2097.
    • (1997) Nucleic Acids Res. , vol.25 , pp. 2091-2097
    • Petersen, B.Ø.1    Shuman, S.2
  • 23
    • 0031058037 scopus 로고    scopus 로고
    • Histidine-265 is important for covalent catalysis by vaccinia topoisomerase and is conserved in all eukaryotic type I enzymes
    • Petersen, B.Ø., and Shuman, S. (1997b). Histidine-265 is important for covalent catalysis by vaccinia topoisomerase and is conserved in all eukaryotic type I enzymes. J. Biol. Chem. 272, 3891-3896.
    • (1997) J. Biol. Chem. , vol.272 , pp. 3891-3896
    • Petersen, B.Ø.1    Shuman, S.2
  • 24
    • 0030601823 scopus 로고    scopus 로고
    • Mutations within a conserved region of vaccinia topoisomerase affect the cleavage-religation equilibrium
    • Petersen, B.Ø., Wittschieben, J., and Shuman, S. (1996). Mutations within a conserved region of vaccinia topoisomerase affect the cleavage-religation equilibrium. J. Mol. Biol. 263, 181-195.
    • (1996) J. Mol. Biol. , vol.263 , pp. 181-195
    • Petersen, B.Ø.1    Wittschieben, J.2    Shuman, S.3
  • 25
    • 0031003701 scopus 로고    scopus 로고
    • Effects of uracil incorporation, DNA mismatches, and abasic sites on DNA cleavage and religation activites of mammalian topoisomerase I
    • Porquier, P., Ueng, L., Kohlhagen, G., Mazumder, A., Gupta, M., Kohn, K.W., and Pommier, Y. (1997). Effects of uracil incorporation, DNA mismatches, and abasic sites on DNA cleavage and religation activites of mammalian topoisomerase I. J. Biol. Chem. 272, 7792-7796.
    • (1997) J. Biol. Chem. , vol.272 , pp. 7792-7796
    • Porquier, P.1    Ueng, L.2    Kohlhagen, G.3    Mazumder, A.4    Gupta, M.5    Kohn, K.W.6    Pommier, Y.7
  • 26
    • 0025155503 scopus 로고
    • Yeast tRNA-splicing endonuclease is a heterotrimeric enzyme
    • Rauhut, R., Green, P.R., and Abelson, J. (1990). Yeast tRNA-splicing endonuclease is a heterotrimeric enzyme. J. Biol. Chem. 265, 18180-18184.
    • (1990) J. Biol. Chem. , vol.265 , pp. 18180-18184
    • Rauhut, R.1    Green, P.R.2    Abelson, J.3
  • 27
    • 0021832279 scopus 로고
    • The enzymatic conversion of 3′-phosphate terminated RNA chains to 2′, 3′-cyclic phosphate derivatives
    • Reinberg, D., Arenas, J., and Hurwitz, J. (1985). The enzymatic conversion of 3′-phosphate terminated RNA chains to 2′, 3′-cyclic phosphate derivatives. J. Biol. Chem. 260, 6088-6097.
    • (1985) J. Biol. Chem. , vol.260 , pp. 6088-6097
    • Reinberg, D.1    Arenas, J.2    Hurwitz, J.3
  • 28
    • 0028130224 scopus 로고
    • Vaccinia topoisomerase binds circumferentially to DNA
    • Sekiguchi, J., and Shuman, S. (1994a). Vaccinia topoisomerase binds circumferentially to DNA. J. Biol. Chem. 269, 31731-31734.
    • (1994) J. Biol. Chem. , vol.269 , pp. 31731-31734
    • Sekiguchi, J.1    Shuman, S.2
  • 29
    • 0028641159 scopus 로고
    • Requirements for noncovalent binding of vaccinia topoisomerase I to duplex DNA
    • Sekiguchi, J., and Shuman, S. (1994b). Requirements for noncovalent binding of vaccinia topoisomerase I to duplex DNA. Nucleic Acids Res. 22, 5360-5365.
    • (1994) Nucleic Acids Res. , vol.22 , pp. 5360-5365
    • Sekiguchi, J.1    Shuman, S.2
  • 30
    • 0029076737 scopus 로고
    • Proteolytic footprinting of vaccinia topoisomerase I bound to DNA
    • Sekiguchi, J., and Shuman, S. (1995). Proteolytic footprinting of vaccinia topoisomerase I bound to DNA. J. Biol. Chem. 270, 11636-11645.
    • (1995) J. Biol. Chem. , vol.270 , pp. 11636-11645
    • Sekiguchi, J.1    Shuman, S.2
  • 31
    • 0030054972 scopus 로고    scopus 로고
    • Identification of contacts between topoisomerase land its target DNA by site-specific crosslinking
    • Sekiguchi, J., and Shuman, S. (1996). Identification of contacts between topoisomerase land its target DNA by site-specific crosslinking. EMBO J. 15, 3448-3457.
    • (1996) EMBO J. , vol.15 , pp. 3448-3457
    • Sekiguchi, J.1    Shuman, S.2
  • 32
    • 0030767872 scopus 로고    scopus 로고
    • Ligation of RNA-containing duplexes by vaccinia DNA ligase
    • in press
    • Sekiguchi, J., and Shuman, S. (1997). Ligation of RNA-containing duplexes by vaccinia DNA ligase. Biochemistry, in press.
    • (1997) Biochemistry
    • Sekiguchi, J.1    Shuman, S.2
  • 33
    • 0030061445 scopus 로고    scopus 로고
    • Resolution of Holliday junctions by eukaryotic DNA topoisomerase I
    • Sekiguchi, J., Seeman, N.C., and Shuman, S. (1996). Resolution of Holliday junctions by eukaryotic DNA topoisomerase I. Proc. Natl. Acad. Sci. USA 93, 785-789.
    • (1996) Proc. Natl. Acad. Sci. USA , vol.93 , pp. 785-789
    • Sekiguchi, J.1    Seeman, N.C.2    Shuman, S.3
  • 34
    • 0030917446 scopus 로고    scopus 로고
    • Kinetic analysis of DNA and RNA strand transfer reactions catalyzed by vaccinia topoisomerase
    • Sekiguchi, J., Cheng, C., and Shuman, S. (1997). Kinetic analysis of DNA and RNA strand transfer reactions catalyzed by vaccinia topoisomerase. J. Biol. Chem. 272, 15721-15728.
    • (1997) J. Biol. Chem. , vol.272 , pp. 15721-15728
    • Sekiguchi, J.1    Cheng, C.2    Shuman, S.3
  • 35
    • 0025964516 scopus 로고
    • Site-specific DNA cleavage by vaccinia virus DNA topoisomerase I: Role of nucleotide sequence and DNA secondary structure
    • Shuman, S. (1991a). Site-specific DNA cleavage by vaccinia virus DNA topoisomerase I: role of nucleotide sequence and DNA secondary structure. J. Biol. Chem. 266, 1796-1803.
    • (1991) J. Biol. Chem. , vol.266 , pp. 1796-1803
    • Shuman, S.1
  • 36
    • 0025735876 scopus 로고
    • Site-specific interaction of vaccinia virus DNA topoisomerase I with duplex DNA: Minimal DNA substrate for strand cleavage in vitro
    • Shuman, S. (1991b). Site-specific interaction of vaccinia virus DNA topoisomerase I with duplex DNA: minimal DNA substrate for strand cleavage in vitro. J. Biol. Chem. 266, 11372-11379.
    • (1991) J. Biol. Chem. , vol.266 , pp. 11372-11379
    • Shuman, S.1
  • 37
    • 0026657545 scopus 로고
    • DNA strand transfer reactions catalyzed by vaccinia DNA topoisomerase I
    • Shuman, S. (1992a). DNA strand transfer reactions catalyzed by vaccinia DNA topoisomerase I. J. Biol. Chem. 267, 8620-8627.
    • (1992) J. Biol. Chem. , vol.267 , pp. 8620-8627
    • Shuman, S.1
  • 38
    • 0026806143 scopus 로고
    • Two classes of DNA end-joining reactions catalyzed by vaccinia topoisomerase I
    • Shuman, S. (1992b). Two classes of DNA end-joining reactions catalyzed by vaccinia topoisomerase I. J. Biol. Chem. 267, 16755-16758.
    • (1992) J. Biol. Chem. , vol.267 , pp. 16755-16758
    • Shuman, S.1
  • 39
    • 0025144958 scopus 로고
    • Specific DNA cleavage and binding by vaccinia virus DNA topoisomerase I
    • Shuman, S., and Prescott, J. (1990). Specific DNA cleavage and binding by vaccinia virus DNA topoisomerase I. J. Biol. Chem. 265, 17826-17836.
    • (1990) J. Biol. Chem. , vol.265 , pp. 17826-17836
    • Shuman, S.1    Prescott, J.2
  • 40
    • 0024828122 scopus 로고
    • Mapping the active site tyrosine of vaccinia virus DNA topoisomerase I
    • Shuman, S., Kane, E.M., and Morham, S.G. (1989). Mapping the active site tyrosine of vaccinia virus DNA topoisomerase I. Proc. Natl. Acad. Sci. USA 86, 9793-9797.
    • (1989) Proc. Natl. Acad. Sci. USA , vol.86 , pp. 9793-9797
    • Shuman, S.1    Kane, E.M.2    Morham, S.G.3
  • 41
    • 0024411478 scopus 로고
    • Interactions between eukaryotic DNA topoisomerase I and a specific binding sequence
    • Stevnser, T., Mortensen, U.H., Westergaard, O., and Bonven, B.J. (1989). Interactions between eukaryotic DNA topoisomerase I and a specific binding sequence. J. Biol. Chem. 264, 10110-10113.
    • (1989) J. Biol. Chem. , vol.264 , pp. 10110-10113
    • Stevnser, T.1    Mortensen, U.H.2    Westergaard, O.3    Bonven, B.J.4
  • 42
    • 0029986467 scopus 로고    scopus 로고
    • Biochemical and biophysical analyses of recombinant forms of human topoisomerase I
    • Stewart, L., Ireton, G.C., Parker, L.H., Madden, K.R., and Champoux, J.J. (1996). Biochemical and biophysical analyses of recombinant forms of human topoisomerase I. J. Biol. Chem. 271, 7593-7601.
    • (1996) J. Biol. Chem. , vol.271 , pp. 7593-7601
    • Stewart, L.1    Ireton, G.C.2    Parker, L.H.3    Madden, K.R.4    Champoux, J.J.5
  • 43
    • 0028091124 scopus 로고
    • Vaccinia DNA topoisomerase I: Single-turnover and steady-state kinetic analysis of the DNA strand cleavage and ligation reactions
    • Stivers, J.T., Shuman, S., and Mildvan, A.S. (1994). Vaccinia DNA topoisomerase I: Single-turnover and steady-state kinetic analysis of the DNA strand cleavage and ligation reactions. Biochemistry 33, 327-339.
    • (1994) Biochemistry , vol.33 , pp. 327-339
    • Stivers, J.T.1    Shuman, S.2    Mildvan, A.S.3
  • 44
    • 0025287261 scopus 로고
    • Minimal DNA duplex requirements for topoisomerase I-mediated cleavage in vitro
    • Svejstrup, J.Q., Christiansen, K., Andersen, A.H., Lund, K., and Westergaard, O. (1990). Minimal DNA duplex requirements for topoisomerase I-mediated cleavage in vitro. J. Biol. Chem. 265, 12529-12535.
    • (1990) J. Biol. Chem. , vol.265 , pp. 12529-12535
    • Svejstrup, J.Q.1    Christiansen, K.2    Andersen, A.H.3    Lund, K.4    Westergaard, O.5
  • 45
    • 0030730820 scopus 로고    scopus 로고
    • The yeast tRNA splicing endonuclease: A tetrameric enzyme with two active site subunits homologous to the archael tRNA endonucleases
    • Trotta, C.R., Miao, F., Arn, E.A., Stevens, S.W., Ho, C.K., Rauhut, R., and Abelson, J.N. (1997). The yeast tRNA splicing endonuclease: a tetrameric enzyme with two active site subunits homologous to the archael tRNA endonucleases. Cell 89, 849-858.
    • (1997) Cell , vol.89 , pp. 849-858
    • Trotta, C.R.1    Miao, F.2    Arn, E.A.3    Stevens, S.W.4    Ho, C.K.5    Rauhut, R.6    Abelson, J.N.7
  • 46
    • 0030014783 scopus 로고    scopus 로고
    • DNA topoisomerases
    • Wang, J.C. (1996). DNA topoisomerases. Annu. Rev. Biochem. 65, 635-692.
    • (1996) Annu. Rev. Biochem. , vol.65 , pp. 635-692
    • Wang, J.C.1
  • 48
    • 0030759204 scopus 로고    scopus 로고
    • Mechanism of DNA transesterification by vaccinia topoisomerase: Catalytic contributions of essential residues Arg-130, Gly-132, Tyr-136, and Lys-167
    • in press
    • Wittschieben, J., and Shuman, S. (1997). Mechanism of DNA transesterification by vaccinia topoisomerase: catalytic contributions of essential residues Arg-130, Gly-132, Tyr-136, and Lys-167. Nucleic Acids. Res., in press.
    • (1997) Nucleic Acids. Res.
    • Wittschieben, J.1    Shuman, S.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.