-
1
-
-
70449529433
-
Structure and function of the blood-brain barrier
-
Abbott N. J., Patabendige A. A., Dolman D. E., Yusof S. R., and, Begley D. J., (2010) Structure and function of the blood-brain barrier. Neurobiol. Dis. 37, 13-25.
-
(2010)
Neurobiol. Dis.
, vol.37
, pp. 13-25
-
-
Abbott, N.J.1
Patabendige, A.A.2
Dolman, D.E.3
Yusof, S.R.4
Begley, D.J.5
-
2
-
-
20544465654
-
Multidrug-resistant cancer cells contain two populations of P-glycoprotein with differently stimulated P-gp ATPase activities: Evidence from atomic force microscopy and biochemical analysis
-
DOI 10.1042/BJ20041999
-
Barakat S., Gayet L., Dayan G., Labialle S., Lazar A., Oleinikov V., Coleman A. W., and, Baggetto L. G., (2005) Multidrug-resistant cancer cells contain two populations of P-glycoprotein with differently stimulated P-gp ATPase activities: evidence from atomic force microscopy and biochemical analysis. Biochem. J. 388, 563-571. (Pubitemid 40839934)
-
(2005)
Biochemical Journal
, vol.388
, Issue.2
, pp. 563-571
-
-
Barakat, S.1
Gayet, L.2
Dayan, G.3
Labialle, S.4
Lazar, A.5
Oleinikov, V.6
Coleman, A.W.7
Baggetto, L.G.8
-
3
-
-
33947279373
-
Modulation of p-glycoprotein function by caveolin-1 phosphorylation
-
DOI 10.1111/j.1471-4159.2006.04410.x
-
Barakat S., Demeule M., Pilorget A., Regina A., Gingras D., Baggetto L. G., and, Beliveau R., (2007) Modulation of p-glycoprotein function by caveolin-1 phosphorylation. J. Neurochem. 101, 1-8. (Pubitemid 46426486)
-
(2007)
Journal of Neurochemistry
, vol.101
, Issue.1
, pp. 1-8
-
-
Barakat, S.1
Demeule, M.2
Pilorget, A.3
Regina, A.4
Gingras, D.5
Baggetto, L.G.6
Beliveau, R.7
-
4
-
-
44749088919
-
Regulation of brain endothelial cells migration and angiogenesis by P-glycoprotein/caveolin-1 interaction
-
Barakat S., Turcotte S., Demeule M., Lachambre M. P., Regina A., Baggetto L. G., and, Beliveau R., (2008) Regulation of brain endothelial cells migration and angiogenesis by P-glycoprotein/caveolin-1 interaction. Biochem. Biophys. Res. Commun. 372, 440-446.
-
(2008)
Biochem. Biophys. Res. Commun.
, vol.372
, pp. 440-446
-
-
Barakat, S.1
Turcotte, S.2
Demeule, M.3
Lachambre, M.P.4
Regina, A.5
Baggetto, L.G.6
Beliveau, R.7
-
5
-
-
80053504148
-
Blood-brain barrier p-glycoprotein function in neurodegenerative disease
-
Bartels A. L., (2011) Blood-brain barrier p-glycoprotein function in neurodegenerative disease. Curr. Pharm. Des. 17, 2771-2777.
-
(2011)
Curr. Pharm. Des.
, vol.17
, pp. 2771-2777
-
-
Bartels, A.L.1
-
6
-
-
12744253433
-
Modulation of p-glycoprotein transport function at the blood-brain barrier
-
Bauer B., Hartz A. M., Fricker G., and, Miller D. S., (2005) Modulation of p-glycoprotein transport function at the blood-brain barrier. Exp. Biol. Med. (Maywood) 230, 118-127.
-
(2005)
Exp. Biol. Med. (Maywood)
, vol.230
, pp. 118-127
-
-
Bauer, B.1
Hartz, A.M.2
Fricker, G.3
Miller, D.S.4
-
7
-
-
0030823912
-
P-glycoprotein is strongly expressed in the luminal membranes of the endothelium of blood vessels in the brain
-
Beaulieu E., Demeule M., Ghitescu L., and, Beliveau R., (1997) P-glycoprotein is strongly expressed in the luminal membranes of the endothelium of blood vessels in the brain. Biochem. J. 326, 539-544. (Pubitemid 27417234)
-
(1997)
Biochemical Journal
, vol.326
, Issue.2
, pp. 539-544
-
-
Beaulieu, E.1
Demeule, M.2
Ghitescu, L.3
Beliveau, R.4
-
8
-
-
33748949567
-
In situ localization of P-glycoprotein (ABCB1) in human and rat brain
-
DOI 10.1369/jhc.5A6870.2006
-
Bendayan R., Ronaldson P. T., Gingras D., and, Bendayan M., (2006) In situ localization of P-glycoprotein (ABCB1) in human and rat brain. J. Histochem. Cytochem. 54, 1159-1167. (Pubitemid 44434719)
-
(2006)
Journal of Histochemistry and Cytochemistry
, vol.54
, Issue.10
, pp. 1159-1167
-
-
Bendayan, R.1
Ronaldson, P.T.2
Gingras, D.3
Bendayan, M.4
-
9
-
-
33845764296
-
A guided tour into subcellular colocalization analysis in light microscopy
-
DOI 10.1111/j.1365-2818.2006.01706.x
-
Bolte S., and, Cordelieres F. P., (2006) A guided tour into subcellular colocalization analysis in light microscopy. J. Microsc. 224, 213-232. (Pubitemid 46010930)
-
(2006)
Journal of Microscopy
, vol.224
, Issue.3
, pp. 213-232
-
-
Bolte, S.1
Cordelieres, F.P.2
-
10
-
-
33646790191
-
Differential in vivo sensitivity to inhibition of P-glycoprotein located in lymphocytes, testes, and the blood-brain barrier
-
DOI 10.1124/jpet.105.099648
-
Choo E. F., Kurnik D., Muszkat M., et al. (2006) Differential in vivo sensitivity to inhibition of P-glycoprotein located in lymphocytes, testes, and the blood-brain barrier. J. Pharmacol. Exp. Ther. 317, 1012-1018. (Pubitemid 43764103)
-
(2006)
Journal of Pharmacology and Experimental Therapeutics
, vol.317
, Issue.3
, pp. 1012-1018
-
-
Choo, E.F.1
Kurnik, D.2
Muszkat, M.3
Ohkubo, T.4
Shay, S.D.5
Higginbotham, J.N.6
Glaeser, H.7
Kim, R.B.8
Wood, A.J.J.9
Wilkinson, G.R.10
-
11
-
-
0000712439
-
Multidrug-resistance gene (P-glycoprotein) is expressed by endothelial cells at blood-brain barrier sites
-
DOI 10.1073/pnas.86.2.695
-
Cordon-Cardo C., O'Brien J. P., Casals D., Rittman-Grauer L., Biedler J. L., Melamed M. R., and, Bertino J. R., (1989) Multidrug-resistance gene (P-glycoprotein) is expressed by endothelial cells at blood-brain barrier sites. Proc. Natl Acad. Sci. USA 86, 695-698. (Pubitemid 19037807)
-
(1989)
Proceedings of the National Academy of Sciences of the United States of America
, vol.86
, Issue.2
, pp. 695-698
-
-
Cordon-Cardo, C.1
O'Brien, J.P.2
Casals, D.3
Rittman-Grauer, L.4
Biedler, J.L.5
Melamed, M.R.6
Bertino, J.R.7
-
12
-
-
80055107174
-
The role of p-glycoprotein in psychiatric disorders: A reliable guard of the brain?
-
De Klerk O. L., Bosker F. J., Luurtsema G., Nolte I. M., Dierckx R., Den Boer J. A., and, Potschka H., (2011) The role of p-glycoprotein in psychiatric disorders: a reliable guard of the brain? Cent. Nerv. Syst. Agents Med. Chem. 11, 197-209.
-
(2011)
Cent. Nerv. Syst. Agents Med. Chem.
, vol.11
, pp. 197-209
-
-
De Klerk, O.L.1
Bosker, F.J.2
Luurtsema, G.3
Nolte, I.M.4
Dierckx, R.5
Den Boer, J.A.6
Potschka, H.7
-
13
-
-
0033963650
-
P-glycoprotein is localized in caveolae in resistant cells and in brain capillaries
-
DOI 10.1016/S0014-5793(00)01087-5, PII S0014579300010875
-
Demeule M., Jodoin J., Gingras D., and, Beliveau R., (2000) P-glycoprotein is localized in caveolae in resistant cells and in brain capillaries. FEBS Lett. 466, 219-224. (Pubitemid 30069829)
-
(2000)
FEBS Letters
, vol.466
, Issue.2-3
, pp. 219-224
-
-
Demeule, M.1
Jodoin, J.2
Gingras, D.3
Beliveau, R.4
-
14
-
-
75149143363
-
ABC transporters in cancer: More than just drug efflux pumps
-
Fletcher J. I., Haber M., Henderson M. J., and, Norris M. D., (2010) ABC transporters in cancer: more than just drug efflux pumps. Nat. Rev. Cancer 10, 147-156.
-
(2010)
Nat. Rev. Cancer
, vol.10
, pp. 147-156
-
-
Fletcher, J.I.1
Haber, M.2
Henderson, M.J.3
Norris, M.D.4
-
15
-
-
66249146356
-
Rhodamine inhibitors of P-glycoprotein: An amide/thioamide "switch" for ATPase activity
-
Gannon M. K. II, Holt J. J., Bennett S. M., et al. (2009) Rhodamine inhibitors of P-glycoprotein: an amide/thioamide "switch" for ATPase activity. J. Med. Chem. 52, 3328-3341.
-
(2009)
J. Med. Chem.
, vol.52
, pp. 3328-3341
-
-
Gannon, I.I.M.K.1
Holt, J.J.2
Bennett, S.M.3
-
16
-
-
77956459031
-
Expression and clinical significance of multidrug resistance proteins in brain tumors
-
Guo Z., Zhu J., Zhao L., Luo Q., and, Jin X., (2010) Expression and clinical significance of multidrug resistance proteins in brain tumors. J. Exp. Clin. Cancer Res. 29, 122.
-
(2010)
J. Exp. Clin. Cancer Res.
, vol.29
, pp. 122
-
-
Guo, Z.1
Zhu, J.2
Zhao, L.3
Luo, Q.4
Jin, X.5
-
17
-
-
0023924046
-
A new and sensitive method for measuring thermal nociception in cutaneous hyperalgesia
-
Hargreaves K., Dubner R., Brown F., Flores C., and, Joris J., (1988) A new and sensitive method for measuring thermal nociception in cutaneous hyperalgesia. Pain 32, 77-88.
-
(1988)
Pain
, vol.32
, pp. 77-88
-
-
Hargreaves, K.1
Dubner, R.2
Brown, F.3
Flores, C.4
Joris, J.5
-
18
-
-
78149477007
-
Regulation of ABC transporters at the blood-brain barrier: New targets for CNS therapy
-
Hartz A. M., and, Bauer B., (2010) Regulation of ABC transporters at the blood-brain barrier: new targets for CNS therapy. Mol. Interv. 10, 293-304.
-
(2010)
Mol. Interv.
, vol.10
, pp. 293-304
-
-
Hartz, A.M.1
Bauer, B.2
-
19
-
-
22944483792
-
The blood-brain barrier/neurovascular unit in health and disease
-
DOI 10.1124/pr.57.2.4
-
Hawkins B. T., and, Davis T. P., (2005) The blood-brain barrier/neurovascular unit in health and disease. Pharmacol. Rev. 57, 173-185. (Pubitemid 41043883)
-
(2005)
Pharmacological Reviews
, vol.57
, Issue.2
, pp. 173-185
-
-
Hawkins, B.T.1
Davis, T.P.2
-
20
-
-
77956268005
-
Rapid loss of blood-brain barrier P-glycoprotein activity through transporter internalization demonstrated using a novel in situ proteolysis protection assay
-
Hawkins B. T., Rigor R. R., and, Miller D. S., (2010) Rapid loss of blood-brain barrier P-glycoprotein activity through transporter internalization demonstrated using a novel in situ proteolysis protection assay. J. Cereb. Blood Flow Metab. 30, 1593-1597.
-
(2010)
J. Cereb. Blood Flow Metab.
, vol.30
, pp. 1593-1597
-
-
Hawkins, B.T.1
Rigor, R.R.2
Miller, D.S.3
-
21
-
-
0036784006
-
Blood-brain barrier tight junctions are altered during a 72-h exposure to lambda-carrageenan-induced inflammatory pain
-
Huber J. D., Hau V. S., Borg L., Campos C. R., Egleton R. D., and, Davis T. P., (2002) Blood-brain barrier tight junctions are altered during a 72-h exposure to lambda-carrageenan-induced inflammatory pain. Am. J. Physiol. Heart Circ. Physiol. 283, H1531-H1537.
-
(2002)
Am. J. Physiol. Heart Circ. Physiol.
, vol.283
-
-
Huber, J.D.1
Hau, V.S.2
Borg, L.3
Campos, C.R.4
Egleton, R.D.5
Davis, T.P.6
-
22
-
-
0037817385
-
Cyclooxygenase-2 is induced in the endothelial cells throughout the central nervous system during carrageenan-induced hind paw inflammation; its possible role in hyperalgesia
-
DOI 10.1046/j.1471-4159.2003.01848.x
-
Ibuki T., Matsumura K., Yamazaki Y., Nozaki T., Tanaka Y., and, Kobayashi S., (2003) Cyclooxygenase-2 is induced in the endothelial cells throughout the central nervous system during carrageenan-induced hind paw inflammation; its possible role in hyperalgesia. J. Neurochem. 86, 318-328. (Pubitemid 36842431)
-
(2003)
Journal of Neurochemistry
, vol.86
, Issue.2
, pp. 318-328
-
-
Ibuki, T.1
Matsumura, K.2
Yamazaki, Y.3
Nozaki, T.4
Tanaka, Y.5
Kobayashi, S.6
-
23
-
-
0345255950
-
P-glycoprotein in blood-brain barrier endothelial cells: Interaction and oligomerization with caveolins
-
DOI 10.1046/j.1471-4159.2003.02081.x
-
Jodoin J., Demeule M., Fenart L., Cecchelli R., Farmer S., Linton K. J., Higgins C. F., and, Beliveau R., (2003) P-glycoprotein in blood-brain barrier endothelial cells: interaction and oligomerization with caveolins. J. Neurochem. 87, 1010-1023. (Pubitemid 37444575)
-
(2003)
Journal of Neurochemistry
, vol.87
, Issue.4
, pp. 1010-1023
-
-
Jodoin, J.1
Demeule, M.2
Fenart, L.3
Cecchelli, R.4
Farmer, S.5
Linton, K.J.6
Higgins, C.F.7
Beliveau, R.8
-
24
-
-
33645830172
-
A surface glycoprotein modulating drug permeability in Chinese hamster ovary cell mutants
-
Juliano R. L., and, Ling V., (1976) A surface glycoprotein modulating drug permeability in Chinese hamster ovary cell mutants. Biochim. Biophys. Acta 455, 152-162.
-
(1976)
Biochim. Biophys. Acta
, vol.455
, pp. 152-162
-
-
Juliano, R.L.1
Ling, V.2
-
25
-
-
70349451693
-
Imaging the function of P-glycoprotein with radiotracers: Pharmacokinetics and in vivo applications
-
Kannan P., John C., Zoghbi S. S., Halldin C., Gottesman M. M., Innis R. B., and, Hall M. D., (2009) Imaging the function of P-glycoprotein with radiotracers: pharmacokinetics and in vivo applications. Clin. Pharmacol. Ther. 86, 368-377.
-
(2009)
Clin. Pharmacol. Ther.
, vol.86
, pp. 368-377
-
-
Kannan, P.1
John, C.2
Zoghbi, S.S.3
Halldin, C.4
Gottesman, M.M.5
Innis, R.B.6
Hall, M.D.7
-
26
-
-
45749138467
-
Reversal of drug resistance in ovarian cancer: Where do we go from here?
-
Kaye S. B., (2008) Reversal of drug resistance in ovarian cancer: where do we go from here? J. Clin. Oncol. 26, 2616-2618.
-
(2008)
J. Clin. Oncol.
, vol.26
, pp. 2616-2618
-
-
Kaye, S.B.1
-
27
-
-
65649122726
-
Lattices, rafts, and scaffolds: Domain regulation of receptor signaling at the plasma membrane
-
Lajoie P., Goetz J. G., Dennis J. W., and, Nabi I. R., (2009) Lattices, rafts, and scaffolds: domain regulation of receptor signaling at the plasma membrane. J. Cell Biol. 185, 381-385.
-
(2009)
J. Cell Biol.
, vol.185
, pp. 381-385
-
-
Lajoie, P.1
Goetz, J.G.2
Dennis, J.W.3
Nabi, I.R.4
-
28
-
-
4344632950
-
Mrp4 confers resistance to topotecan and protects the brain from chemotherapy
-
DOI 10.1128/MCB.24.17.7612-7621.2004
-
Leggas M., Adachi M., Scheffer G. L., et al. (2004) Mrp4 confers resistance to topotecan and protects the brain from chemotherapy. Mol. Cell. Biol. 24, 7612-7621. (Pubitemid 39121487)
-
(2004)
Molecular and Cellular Biology
, vol.24
, Issue.17
, pp. 7612-7621
-
-
Leggas, M.1
Adachi, M.2
Scheffer, G.L.3
Sun, D.4
Wielinga, P.5
Du, G.6
Mercer, K.E.7
Zhuang, Y.8
Panetta, J.C.9
Johnston, B.10
Scheper, R.J.11
Stewart, C.F.12
Schuetz, J.D.13
-
29
-
-
33845463597
-
Interaction of macrocyclic lactones with P-glycoprotein: Structure-affinity relationship
-
DOI 10.1016/j.ejps.2006.10.004, PII S0928098706002995
-
Lespine A., Martin S., Dupuy J., Roulet A., Pineau T., Orlowski S., and, Alvinerie M., (2007) Interaction of macrocyclic lactones with P-glycoprotein: structure-affinity relationship. Eur. J. Pharm. Sci. 30, 84-94. (Pubitemid 44908930)
-
(2007)
European Journal of Pharmaceutical Sciences
, vol.30
, Issue.1
, pp. 84-94
-
-
Lespine, A.1
Martin, S.2
Dupuy, J.3
Roulet, A.4
Pineau, T.5
Orlowski, S.6
Alvinerie, M.7
-
30
-
-
77956247309
-
Oxidative stress increases blood-brain barrier permeability and induces alterations in occludin during hypoxia-reoxygenation
-
Lochhead J. J., McCaffrey G., Quigley C. E., Finch J., DeMarco K. M., Nametz N., and, Davis T. P., (2010) Oxidative stress increases blood-brain barrier permeability and induces alterations in occludin during hypoxia-reoxygenation. J. Cereb. Blood Flow Metab. 30, 1625-1636.
-
(2010)
J. Cereb. Blood Flow Metab.
, vol.30
, pp. 1625-1636
-
-
Lochhead, J.J.1
McCaffrey, G.2
Quigley, C.E.3
Finch, J.4
Demarco, K.M.5
Nametz, N.6
Davis, T.P.7
-
31
-
-
0029910016
-
The minimum functional unit of human P-glycoprotein appears to be a monomer
-
DOI 10.1074/jbc.271.44.27488
-
Loo T. W., and, Clarke D. M., (1996) The minimum functional unit of human P-glycoprotein appears to be a monomer. J. Biol. Chem. 271, 27488-27492. (Pubitemid 26367310)
-
(1996)
Journal of Biological Chemistry
, vol.271
, Issue.44
, pp. 27488-27492
-
-
Loo, T.W.1
Clarke, D.M.2
-
32
-
-
0034733677
-
Drug-stimulated ATPase activity of human P-glycoprotein is blocked by disulfide cross-linking between the nucleotide-binding sites
-
DOI 10.1074/jbc.C000222200
-
Loo T. W., and, Clarke D. M., (2000) Drug-stimulated ATPase activity of human P-glycoprotein is blocked by disulfide cross-linking between the nucleotide-binding sites. J. Biol. Chem. 275, 19435-19438. (Pubitemid 30441531)
-
(2000)
Journal of Biological Chemistry
, vol.275
, Issue.26
, pp. 19435-19438
-
-
Loo, T.W.1
Clarke, D.M.2
-
33
-
-
77951877993
-
Human P-glycoprotein is active when the two halves are clamped together in the closed conformation
-
Loo T. W., Bartlett M. C., and, Clarke D. M., (2010) Human P-glycoprotein is active when the two halves are clamped together in the closed conformation. Biochem. Biophys. Res. Commun. 395, 436-440.
-
(2010)
Biochem. Biophys. Res. Commun.
, vol.395
, pp. 436-440
-
-
Loo, T.W.1
Bartlett, M.C.2
Clarke, D.M.3
-
34
-
-
22244469306
-
A simplified method for the preparation of detergent-free lipid rafts
-
Macdonald J. L., and, Pike L. J., (2005) A simplified method for the preparation of detergent-free lipid rafts. J. Lipid Res. 46, 1061-1067.
-
(2005)
J. Lipid Res.
, vol.46
, pp. 1061-1067
-
-
MacDonald, J.L.1
Pike, L.J.2
-
35
-
-
42649105392
-
Tight junctions contain oligomeric protein assembly critical for maintaining blood-brain barrier integrity in vivo
-
McCaffrey G., Staatz W. D., Quigley C. A., Nametz N., Seelbach M. J., Campos C. R., Brooks T. A., Egleton R. D., and, Davis T. P., (2007) Tight junctions contain oligomeric protein assembly critical for maintaining blood-brain barrier integrity in vivo. J. Neurochem. 103, 2540-2555.
-
(2007)
J. Neurochem.
, vol.103
, pp. 2540-2555
-
-
McCaffrey, G.1
Staatz, W.D.2
Quigley, C.A.3
Nametz, N.4
Seelbach, M.J.5
Campos, C.R.6
Brooks, T.A.7
Egleton, R.D.8
Davis, T.P.9
-
36
-
-
50849106047
-
Occludin oligomeric assembly at tight junctions of the blood-brain barrier is disrupted by peripheral inflammatory hyperalgesia
-
McCaffrey G., Seelbach M. J., Staatz W. D., Nametz N., Quigley C., Campos C. R., Brooks T. A., and, Davis T. P., (2008) Occludin oligomeric assembly at tight junctions of the blood-brain barrier is disrupted by peripheral inflammatory hyperalgesia. J. Neurochem. 106, 2395-2409.
-
(2008)
J. Neurochem.
, vol.106
, pp. 2395-2409
-
-
McCaffrey, G.1
Seelbach, M.J.2
Staatz, W.D.3
Nametz, N.4
Quigley, C.5
Campos, C.R.6
Brooks, T.A.7
Davis, T.P.8
-
37
-
-
67449128444
-
Occludin oligomeric assemblies at tight junctions of the blood-brain barrier are altered by hypoxia and reoxygenation stress
-
McCaffrey G., Willis C. L., Staatz W. D., Nametz N., Quigley C. A., Hom S., Lochhead J. J., and, Davis T. P., (2009) Occludin oligomeric assemblies at tight junctions of the blood-brain barrier are altered by hypoxia and reoxygenation stress. J. Neurochem. 110, 58-71.
-
(2009)
J. Neurochem.
, vol.110
, pp. 58-71
-
-
McCaffrey, G.1
Willis, C.L.2
Staatz, W.D.3
Nametz, N.4
Quigley, C.A.5
Hom, S.6
Lochhead, J.J.7
Davis, T.P.8
-
38
-
-
77953687856
-
Regulation of P-glycoprotein and other ABC drug transporters at the blood-brain barrier
-
Miller D. S., (2010) Regulation of P-glycoprotein and other ABC drug transporters at the blood-brain barrier. Trends Pharmacol. Sci. 31, 246-254.
-
(2010)
Trends Pharmacol. Sci.
, vol.31
, pp. 246-254
-
-
Miller, D.S.1
-
39
-
-
46949098349
-
Modulation of P-glycoprotein at the blood-brain barrier: Opportunities to improve central nervous system pharmacotherapy
-
DOI 10.1124/pr.107.07109
-
Miller D. S., Bauer B., and, Hartz A. M., (2008) Modulation of P-glycoprotein at the blood-brain barrier: opportunities to improve central nervous system pharmacotherapy. Pharmacol. Rev. 60, 196-209. (Pubitemid 351962009)
-
(2008)
Pharmacological Reviews
, vol.60
, Issue.2
, pp. 196-209
-
-
Miller, D.S.1
Bauer, B.2
Hartz, A.M.S.3
-
40
-
-
0029003904
-
P-glycoprotein stability is affected by serum deprivation and high cell density in multidrug-resistant cells
-
Muller C., Laurent G., and, Ling V., (1995) P-glycoprotein stability is affected by serum deprivation and high cell density in multidrug-resistant cells. J. Cell. Physiol. 163, 538-544.
-
(1995)
J. Cell. Physiol.
, vol.163
, pp. 538-544
-
-
Muller, C.1
Laurent, G.2
Ling, V.3
-
41
-
-
6344265573
-
Expression and immunolocalization of the multidrug resistance proteins, MRP1-MRP6 (ABCC1-ABCC6), in human brain
-
DOI 10.1016/j.neuroscience.2004.07.051, PII S0306452204007171
-
Nies A. T., Jedlitschky G., Konig J., Herold-Mende C., Steiner H. H., Schmitt H. P., and, Keppler D., (2004) Expression and immunolocalization of the multidrug resistance proteins, MRP1-MRP6 (ABCC1-ABCC6), in human brain. Neuroscience 129, 349-360. (Pubitemid 39388854)
-
(2004)
Neuroscience
, vol.129
, Issue.2
, pp. 349-360
-
-
Nies, A.T.1
Jedlitschky, G.2
Konig, J.3
Herold-Mende, C.4
Steiner, H.H.5
Schmitt, H.-P.6
Keppler, D.7
-
42
-
-
77952971657
-
The role of cerebral vascular NFkappaB in LPS-induced inflammation: Differential regulation of efflux transporter and transporting cytokine receptors
-
Pan W., Yu C., Hsuchou H., and, Kastin A. J., (2010) The role of cerebral vascular NFkappaB in LPS-induced inflammation: differential regulation of efflux transporter and transporting cytokine receptors. Cell. Physiol. Biochem. 25, 623-630.
-
(2010)
Cell. Physiol. Biochem.
, vol.25
, pp. 623-630
-
-
Pan, W.1
Yu, C.2
Hsuchou, H.3
Kastin, A.J.4
-
43
-
-
34547637590
-
Drug targeting to the brain
-
DOI 10.1007/s11095-007-9324-2
-
Pardridge W. M., (2007) Drug targeting to the brain. Pharm. Res. 24, 1733-1744. (Pubitemid 47206623)
-
(2007)
Pharmaceutical Research
, vol.24
, Issue.9
, pp. 1733-1744
-
-
Pardridge, W.M.1
-
44
-
-
76749087401
-
Regulation of BCRP (ABCG2) and P-glycoprotein (ABCB1) by cytokines in a model of the human blood-brain barrier
-
Poller B., Drewe J., Krahenbuhl S., Huwyler J., and, Gutmann H., (2010) Regulation of BCRP (ABCG2) and P-glycoprotein (ABCB1) by cytokines in a model of the human blood-brain barrier. Cell. Mol. Neurobiol. 30, 63-70.
-
(2010)
Cell. Mol. Neurobiol.
, vol.30
, pp. 63-70
-
-
Poller, B.1
Drewe, J.2
Krahenbuhl, S.3
Huwyler, J.4
Gutmann, H.5
-
45
-
-
0028203332
-
Detection of oligomeric and monomeric forms of P-glycoprotein in multidrug resistant cells
-
Poruchynsky M. S., and, Ling V., (1994) Detection of oligomeric and monomeric forms of P-glycoprotein in multidrug resistant cells. Biochemistry 33, 4163-4174. (Pubitemid 24140600)
-
(1994)
Biochemistry
, vol.33
, Issue.14
, pp. 4163-4174
-
-
Poruchynsky, M.S.1
Ling, V.2
-
46
-
-
77955316820
-
Modulating P-glycoprotein regulation: Future perspectives for pharmacoresistant epilepsies?
-
Potschka H., (2010a) Modulating P-glycoprotein regulation: future perspectives for pharmacoresistant epilepsies? Epilepsia 51, 1333-1347.
-
(2010)
Epilepsia
, vol.51
, pp. 1333-1347
-
-
Potschka, H.1
-
47
-
-
72049119592
-
Targeting regulation of ABC efflux transporters in brain diseases: A novel therapeutic approach
-
Potschka H., (2010b) Targeting regulation of ABC efflux transporters in brain diseases: a novel therapeutic approach. Pharmacol. Ther. 125, 118-127.
-
(2010)
Pharmacol. Ther.
, vol.125
, pp. 118-127
-
-
Potschka, H.1
-
48
-
-
26944437142
-
Phospho-caveolin-1 mediates integrin-regulated membrane domain internalization
-
DOI 10.1038/ncb1293, PII N1293
-
del Pozo M. A., Balasubramanian N., Alderson N. B., Kiosses W. B., Grande-Garcia A., Anderson R. G., and, Schwartz M. A., (2005) Phospho-caveolin-1 mediates integrin-regulated membrane domain internalization. Nat. Cell Biol. 7, 901-908. (Pubitemid 41486291)
-
(2005)
Nature Cell Biology
, vol.7
, Issue.9
, pp. 901-908
-
-
Del Pozo, M.A.1
Balasubramanian, N.2
Alderson, N.B.3
Kiosses, W.B.4
Grande-Garcia, A.5
Anderson, R.G.W.6
Schwartz, M.A.7
-
49
-
-
0014109002
-
Fine structural localization of a blood-brain barrier to exogenous peroxidase
-
Reese T. S., and, Karnovsky M. J., (1967) Fine structural localization of a blood-brain barrier to exogenous peroxidase. J. Cell Biol. 34, 207-217.
-
(1967)
J. Cell Biol.
, vol.34
, pp. 207-217
-
-
Reese, T.S.1
Karnovsky, M.J.2
-
50
-
-
55049106412
-
A critical overview of the influence of inflammation and infection on P-glycoprotein expression and activity in the brain
-
Roberts D. J., and, Goralski K. B., (2008) A critical overview of the influence of inflammation and infection on P-glycoprotein expression and activity in the brain. Expert Opin. Drug Metab. Toxicol. 4, 1245-1264.
-
(2008)
Expert Opin. Drug Metab. Toxicol.
, vol.4
, pp. 1245-1264
-
-
Roberts, D.J.1
Goralski, K.B.2
-
51
-
-
70349218003
-
P-glycoprotein expression in immortalised rat brain endothelial cells: Comparisons following exogenously applied hydrogen peroxide and after hypoxia-reoxygenation
-
Robertson S. J., Kania K. D., Hladky S. B., and, Barrand M. A., (2009) P-glycoprotein expression in immortalised rat brain endothelial cells: comparisons following exogenously applied hydrogen peroxide and after hypoxia-reoxygenation. J. Neurochem. 111, 132-141.
-
(2009)
J. Neurochem.
, vol.111
, pp. 132-141
-
-
Robertson, S.J.1
Kania, K.D.2
Hladky, S.B.3
Barrand, M.A.4
-
52
-
-
79961195196
-
Targeting blood-brain barrier changes during inflammatory pain: An opportunity for optimizing CNS drug delivery
-
Ronaldson P. T., and, Davis T. P., (2011) Targeting blood-brain barrier changes during inflammatory pain: an opportunity for optimizing CNS drug delivery. Ther. Deliv. 2, 1015-1041.
-
(2011)
Ther. Deliv.
, vol.2
, pp. 1015-1041
-
-
Ronaldson, P.T.1
Davis, T.P.2
-
53
-
-
24644504859
-
11α protein
-
DOI 10.1093/jb/mvi114
-
Rudajev V., Novotny J., Hejnova L., Milligan G., and, Svoboda P., (2005) Dominant portion of thyrotropin-releasing hormone receptor is excluded from lipid domains. Detergent-resistant and detergent-sensitive pools of TRH receptor and Gqalpha/G11alpha protein. J. Biochem. 138, 111-125. (Pubitemid 41265361)
-
(2005)
Journal of Biochemistry
, vol.138
, Issue.2
, pp. 111-125
-
-
Rudajev, V.1
Novotny, J.2
Hejnova, L.3
Milligan, G.4
Svoboda, P.5
-
54
-
-
0029075988
-
Oligomeric structure of caveolin: Implications for caveolae membrane organization
-
Sargiacomo M., Scherer P. E., Tang Z., Kubler E., Song K. S., Sanders M. C., and, Lisanti M. P., (1995) Oligomeric structure of caveolin: implications for caveolae membrane organization. Proc. Natl Acad. Sci. USA 92, 9407-9411.
-
(1995)
Proc. Natl Acad. Sci. USA
, vol.92
, pp. 9407-9411
-
-
Sargiacomo, M.1
Scherer, P.E.2
Tang, Z.3
Kubler, E.4
Song, K.S.5
Sanders, M.C.6
Lisanti, M.P.7
-
55
-
-
48749083091
-
Multidrug resistance-associated protein 4 regulates cAMP-dependent signaling pathways and controls human and rat SMC proliferation
-
Sassi Y., Lipskaia L., Vandecasteele G., et al. (2008) Multidrug resistance-associated protein 4 regulates cAMP-dependent signaling pathways and controls human and rat SMC proliferation. J. Clin. Invest. 118, 2747-2757.
-
(2008)
J. Clin. Invest.
, vol.118
, pp. 2747-2757
-
-
Sassi, Y.1
Lipskaia, L.2
Vandecasteele, G.3
-
56
-
-
0028229150
-
Disruption of the mouse mdr1a P-glycoprotein gene leads to a deficiency in the blood-brain barrier and to increased sensitivity to drugs
-
DOI 10.1016/0092-8674(94)90212-7
-
Schinkel A. H., Smit J. J., van Tellingen O., et al. (1994) Disruption of the mouse mdr1a P-glycoprotein gene leads to a deficiency in the blood-brain barrier and to increased sensitivity to drugs. Cell 77, 491-502. (Pubitemid 24153990)
-
(1994)
Cell
, vol.77
, Issue.4
, pp. 491-502
-
-
Schinkel, A.H.1
Smit, J.J.M.2
Van Tellingen, O.3
Beijnen, J.H.4
Wagenaar, E.5
Van Deemter, L.6
Mol, C.A.A.M.7
Van Der Valk, M.A.8
Robanus-Maandag, E.C.9
Te Riele, H.P.J.10
Berns, A.J.M.11
Borst, P.12
-
57
-
-
34547902120
-
Peripheral inflammatory hyperalgesia modulates morphine delivery to the brain: A role for P-glycoprotein
-
DOI 10.1111/j.1471-4159.2007.04644.x
-
Seelbach M. J., Brooks T. A., Egleton R. D., and, Davis T. P., (2007) Peripheral inflammatory hyperalgesia modulates morphine delivery to the brain: a role for P-glycoprotein. J. Neurochem. 102, 1677-1690. (Pubitemid 47256196)
-
(2007)
Journal of Neurochemistry
, vol.102
, Issue.5
, pp. 1677-1690
-
-
Seelbach, M.J.1
Brooks, T.A.2
Egleton, R.D.3
Davis, T.P.4
-
58
-
-
0033567425
-
Interaction of the P-glycoprotein multidrug transporter (MDR1) with high affinity peptide chemosensitizers in isolated membranes, reconstituted systems, and intact cells
-
DOI 10.1016/S0006-2952(99)00139-2, PII S0006295299001392
-
Sharom F. J., Yu X., Lu P., et al. (1999) Interaction of the P-glycoprotein multidrug transporter (MDR1) with high affinity peptide chemosensitizers in isolated membranes, reconstituted systems, and intact cells. Biochem. Pharmacol. 58, 571-586. (Pubitemid 29296877)
-
(1999)
Biochemical Pharmacology
, vol.58
, Issue.4
, pp. 571-586
-
-
Sharom, F.J.1
Yu, X.2
Lu, P.3
Liu, R.4
Chu, J.W.K.5
Szabo, K.6
Muller, M.7
Hose, C.D.8
Monks, A.9
Varadi, A.10
Seprodi, J.11
Sarkadi, B.12
-
59
-
-
0842284169
-
Multidrug resistance P-glycoprotein: Crucial significance in drug disposition and interaction
-
Sun J., He Z. G., Cheng G., Wang S. J., Hao X. H., and, Zou M. J., (2004) Multidrug resistance P-glycoprotein: crucial significance in drug disposition and interaction. Med. Sci. Monit. 10, RA5-RA14. (Pubitemid 38176014)
-
(2004)
Medical Science Monitor
, vol.10
, Issue.1
-
-
Sun, J.1
He, Z.-G.2
Cheng, G.3
Wang, S.-J.4
Hao, X.-H.5
Zou, M.-J.6
-
60
-
-
33644775686
-
Targeting multidrug resistance in cancer
-
DOI 10.1038/nrd1984, PII N1984
-
Szakacs G., Paterson J. K., Ludwig J. A., Booth-Genthe C., and, Gottesman M. M., (2006) Targeting multidrug resistance in cancer. Nat. Rev. Drug Discov. 5, 219-234. (Pubitemid 43336035)
-
(2006)
Nature Reviews Drug Discovery
, vol.5
, Issue.3
, pp. 219-234
-
-
Szakacs, G.1
Paterson, J.K.2
Ludwig, J.A.3
Booth-Genthe, C.4
Gottesman, M.M.5
-
61
-
-
77950664220
-
Transporters in the brain endothelial barrier
-
Ueno M., Nakagawa T., Wu B., Onodera M., Huang C. L., Kusaka T., Araki N., and, Sakamoto H., (2010) Transporters in the brain endothelial barrier. Curr. Med. Chem. 17, 1125-1138.
-
(2010)
Curr. Med. Chem.
, vol.17
, pp. 1125-1138
-
-
Ueno, M.1
Nakagawa, T.2
Wu, B.3
Onodera, M.4
Huang, C.L.5
Kusaka, T.6
Araki, N.7
Sakamoto, H.8
-
62
-
-
0035920130
-
Cysteines 431 and 1074 are responsible for inhibitory disulfide cross-linking between the two nucleotide-binding sites in human P-glycoprotein
-
Urbatsch I. L., Gimi K., Wilke-Mounts S., Lerner-Marmarosh N., Rousseau M. E., Gros P., and, Senior A. E., (2001) Cysteines 431 and 1074 are responsible for inhibitory disulfide cross-linking between the two nucleotide-binding sites in human P-glycoprotein. J. Biol. Chem. 276, 26980-26987.
-
(2001)
J. Biol. Chem.
, vol.276
, pp. 26980-26987
-
-
Urbatsch, I.L.1
Gimi, K.2
Wilke-Mounts, S.3
Lerner-Marmarosh, N.4
Rousseau, M.E.5
Gros, P.6
Senior, A.E.7
-
63
-
-
79955599523
-
Targeting the neurovascular unit for treatment of neurological disorders
-
Vangilder R. L., Rosen C. L., Barr T. L., and, Huber J. D., (2011) Targeting the neurovascular unit for treatment of neurological disorders. Pharmacol. Ther. 130, 239-247.
-
(2011)
Pharmacol. Ther.
, vol.130
, pp. 239-247
-
-
Vangilder, R.L.1
Rosen, C.L.2
Barr, T.L.3
Huber, J.D.4
-
64
-
-
0036936117
-
Expression of P-glycoprotein in human cerebral cortex microvessels
-
Virgintino D., Robertson D., Errede M., Benagiano V., Girolamo F., Maiorano E., Roncali L., and, Bertossi M., (2002) Expression of P-glycoprotein in human cerebral cortex microvessels. J. Histochem. Cytochem. 50, 1671-1676. (Pubitemid 36078133)
-
(2002)
Journal of Histochemistry and Cytochemistry
, vol.50
, Issue.12
, pp. 1671-1676
-
-
Virgintino, D.1
Robertson, D.2
Errede, M.3
Benagiano, V.4
Girolamo, F.5
Maiorano, E.6
Roncali, L.7
Bertossi, M.8
-
65
-
-
1642306919
-
Olanzapine penetration into brain is greater in transgenic Abcb1a P-glycoprotein-deficient mice than FVB1 (wild-type) animals
-
DOI 10.1038/sj.npp.1300372
-
Wang J. S., Taylor R., Ruan Y., Donovan J. L., Markowitz J. S., and, Lindsay De Vane C., (2004) Olanzapine penetration into brain is greater in transgenic Abcb1a P-glycoprotein-deficient mice than FVB1 (wild-type) animals. Neuropsychopharmacology 29, 551-557. (Pubitemid 38365932)
-
(2004)
Neuropsychopharmacology
, vol.29
, Issue.3
, pp. 551-557
-
-
Wang, J.-S.1
Taylor, R.2
Ruan, Y.3
Donovan, J.L.4
Markowitz, J.S.5
De Vane, C.L.6
-
66
-
-
70349203738
-
Regulation of major efflux transporters under inflammatory conditions at the blood-brain barrier in vitro
-
von Wedel-Parlow M., Wolte P., and, Galla H. J., (2009) Regulation of major efflux transporters under inflammatory conditions at the blood-brain barrier in vitro. J. Neurochem. 111, 111-118.
-
(2009)
J. Neurochem.
, vol.111
, pp. 111-118
-
-
Von Wedel-Parlow, M.1
Wolte, P.2
Galla, H.J.3
-
67
-
-
79955562995
-
H1, a novel derivative of tetrandrine reverse P-glycoprotein-mediated multidrug resistance by inhibiting transport function and expression of P-glycoprotein
-
Wei N., Sun H., Wang F., and, Liu G., (2011) H1, a novel derivative of tetrandrine reverse P-glycoprotein-mediated multidrug resistance by inhibiting transport function and expression of P-glycoprotein. Cancer Chemother. Pharmacol. 67, 1017-1025.
-
(2011)
Cancer Chemother. Pharmacol.
, vol.67
, pp. 1017-1025
-
-
Wei, N.1
Sun, H.2
Wang, F.3
Liu, G.4
-
68
-
-
0024453113
-
Biosynthesis, processing and half-life of P-glycoprotein in a human multidrug-resistant KB cell
-
DOI 10.1016/0304-4165(89)90089-5
-
Yoshimura A., Kuwazuru Y., Sumizawa T., Ikeda S., Ichikawa M., Usagawa T., and, Akiyama S., (1989) Biosynthesis, processing and half-life of P-glycoprotein in a human multidrug-resistant KB cell. Biochim. Biophys. Acta 992, 307-314. (Pubitemid 19220892)
-
(1989)
Biochimica et Biophysica Acta - General Subjects
, vol.992
, Issue.3
, pp. 307-314
-
-
Yoshimura, A.1
Kuwazuru, Y.2
Sumizawa, T.3
Ikeda, S.4
Ichikawa, M.5
Usagawa, T.6
Akiyama, S.7
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